1. Articles mentioning both Dresden University of Technology and Maria Gaertner

    1-25 of 25
    1. Optical Coherence Tomography (OCT) for Time-Resolved Imaging of Alveolar Dynamics in Mechanically Ventilated Rats

      Optical Coherence Tomography (OCT) for Time-Resolved Imaging of Alveolar Dynamics in Mechanically Ventilated Rats
      Though artificial ventilation is an essential life-saving treatment, the mechanical behavior of lung tissue at the alveolar level is still unknown. Therefore, we need to understand the tissue response during artificial ventilation at this microscale in order to develop new and more protective ventilation methods. Optical coherence tomography (OCT) combined with intravital microscopy (IVM) is a promising tool for visualizing lung tissue dynamics with a high spatial and temporal resolution ...
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    2. Imaging of nanoparticle-labeled stem cells using magnetomotive optical coherence tomography, laser speckle reflectometry, and light microscopy

      Imaging of nanoparticle-labeled stem cells using magnetomotive optical coherence tomography, laser speckle reflectometry, and light microscopy
      Cell transplantation and stem cell therapy are promising approaches for regenerative medicine and are of interest to researchers and clinicians worldwide. However, currently, no imaging technique that allows three-dimensional in vivo inspection of therapeutically administered cells in host tissues is available. Therefore, we investigate magnetomotive optical coherence tomography (MM-OCT) of cells labeled with magnetic particles as a potential noninvasive cell tracking method. We develop magnetomotive imaging of mesenchymal stem cells ...
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    3. Investigation Of Rat Lung Tissue Geometry During Total Liquid Ventilation With 4D- Optical Coherence Tomography (OCT) And Intravital Microscopy (IVM)

      Investigation Of Rat Lung Tissue Geometry During Total Liquid Ventilation With 4D- Optical Coherence Tomography (OCT) And Intravital Microscopy (IVM)
      ...erts * RSS (What is this?) Search for Other Articles Google Scholar By author * * Christian Schnabel * Maria Gaertner * Edmund Koch Search in * (_) thoracic * (_) Google Scholar Search Previous Chapter Next...
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    4. Towards a comprehensive eye model for zebrafish retinal imaging using full range spectral domain optical coherence tomography

      Towards a comprehensive eye model for zebrafish retinal imaging using full range spectral domain optical coherence tomography
      ...ensive eye model for zebrafish retinal imaging using full range spectral domain optical coherence tomography Maria Gaertner ; Anke Weber ; Peter Cimalla ; Felix Köttig ; Michael Brand ; Edmund Koch; Towards a comprehens...
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    5. Characterization of Light Lesion Paradigms and Optical Coherence Tomography as Tools to Study Adult Retina Regeneration in Zebrafish

      Characterization of Light Lesion Paradigms and Optical Coherence Tomography as Tools to Study Adult Retina Regeneration in Zebrafish
      Light-induced lesions are a powerful tool to study the amazing ability of photoreceptors to regenerate in the adult zebrafish retina. However, the specificity of the lesion towards photoreceptors or regional differences within the retina are still incompletely understood. We therefore characterized the process of degeneration and regeneration in an established paradigm, using intense white light from a fluorescence lamp on swimming fish (diffuse light lesion). We also designed a new ...
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    6. High-resolution optical coherence tomography in mouse models of genetic and induced retinal degeneration

      High-resolution optical coherence tomography in mouse models of genetic and induced retinal degeneration
      ... and induced retinal degeneration Peter Cimalla ; Madalena Carido ; Sheik Pran Babu ; Tiago Santos-Ferreira ; Maria Gaertner ; Simon Kordowich ; Dierk Wittig ; Marius Ader ; Mike Karl ; Edmund Koch; High-resolution optic...
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    7. An advanced algorithm for dispersion encoded full range frequency domain optical coherence tomography

      An advanced algorithm for dispersion encoded full range frequency domain optical coherence tomography
      Dispersion encoded full range (DEFR) optical coherence tomography (OCT) has become highly attractive as it is a simple way to increase the measurement range of OCT systems. Full range OCT is especially favorable as it does not only increase the measurement range but also shifts the highest sensitivity into the center of the measurement range. While the early versions of DEFR were highly computational expensive, new versions reduce the number ...
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    8. Four-dimensional optical coherence tomography imaging of subpleural alveoli in mice

      Four-dimensional optical coherence tomography imaging of subpleural alveoli in mice
      The development of protective ventilation strategies for patients suffering from life-threatening lung diseases and the promotion of numerical simulation of lung tissue mechanics requires detailed knowledge about the three-dimensional alveolar micro-structure, their dynamics and elastic properties. Subpleural lung tissue can be observed in animal models utilizing optical coherence tomography (OCT) with a high spatial resolution. We present four-dimensional high-speed OCT imaging of single alveoli as a suitable technique for the ...
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    9. A hybrid imaging system for simultaneous ophthalmic optical coherence tomography and dual-channel fluorescence detection in small animal models

      A hybrid imaging system for simultaneous ophthalmic optical coherence tomography and dual-channel fluorescence detection in small animal models
      We present a novel hybrid system that allows simultaneous high-resolution spectral domain optical coherence tomography (OCT) in the near-infrared and single-photon excited fluorescence (SPEF) detection in the green and red visible wavelength range for non-invasive multimodal imaging of the retina in small in vivo animal models such as zebrafish.
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    10. Three-dimensional simultaneous optical coherence tomography and confocal fluorescence microscopy for investigation of lung tissue

      Three-dimensional simultaneous optical coherence tomography and confocal fluorescence microscopy for investigation of lung tissue
      Although several strategies exist for a minimal-invasive treatment of patients with lung failure, the mortality rate of acute respiratory distress syndrome still reaches 30% at minimum. This striking number indicates the necessity of understanding lung dynamics on an alveolar level. To investigate the dynamical behavior on a microscale, we used three-dimensional geometrical and functional imaging to observe tissue parameters including alveolar size and length of embedded elastic fibers during ventilation ...
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    11. Feature Of The Week 5/20/12: Dresden University of Technology Investigates Precision Lung Dynamics Using Four-Dimensional OCT

      Feature Of The Week 5/20/12: Dresden University of Technology Investigates Precision Lung Dynamics Using Four-Dimensional OCT
      ...olar tissue dynamics in animal models.For more information see recent Article. Courtesy Lars Kirsten from the Dresden University of Technology. The treatment of urgent lung diseases, such as the acute respiratory distres...
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    12. Multimodal imaging of lung tissue using optical coherence tomography and two photon microscopy

      Multimodal imaging of lung tissue using optical coherence tomography and two photon microscopy
      In the context of protective artificial ventilation strategies for patients with severe lung diseases, the contribution of ventilator settings to tissue changes on the alveolar level of the lung is still a question under debate. To understand the impact of respiratory settings as well as the dynamic process of respiration, high-resolution monitoring and visualization of the dynamics of lung alveoli are essential. An instrument allowing 3D imaging of lung tissue ...
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    13. Quantitative investigation of alveolar structures with OCT using total liquid ventilation during mechanical ventilation

      Quantitative investigation of alveolar structures with OCT using total liquid ventilation during mechanical ventilation
      To develop new treatment possibilities for patients with severe lung diseases it is crucial to understand the lung function on an alveolar level. Optical coherence tomography (OCT) in combination with intravital microscopy (IVM) are used for imaging subpleural alveoli in animal models to gain information about dynamic and morphological changes of lung tissue during mechanical ventilation. The image content suitable for further analysis is influenced by image artifacts caused by ...
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    14. Three-dimensional functional imaging of lung parenchyma using optical coherence tomography combined with confocal fluorescence microscopy

      Three-dimensional functional imaging of lung parenchyma using optical coherence tomography combined with confocal fluorescence microscopy
      ...ntal procedure but also contribute to a thorough description of tissue's morphology and chemical composition. Maria Gaertner, Peter Cimalla, Lilla Knels, Sven Meissner and Edmund Koch, "Three-dimensional functional imagi...
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  2. Organizations in the News

    1. (3 articles) University of Toronto
  3. People in the News

    1. (25 articles) Edmund Koch
    2. (16 articles) Peter Cimalla
    3. (14 articles) Sven Meissner
    4. (7 articles) Lars Kirsten
    5. (5 articles) Julia Walther