1. Articles mentioning both Daniël M. de Bruin and University of Twente

    1-12 of 12
    1. Learning curve and interobserver variance in quantification of the optical coherence tomography attenuation coefficient

      Learning curve and interobserver variance in quantification of the optical coherence tomography attenuation coefficient
      The learning curve and interobserver variance of attenuation coefficient ( OCT ) determination from optical coherence tomography (OCT) images were quantified. The OCT of normal and diseased vulvar tissues was determined at five time points by three novice students and three OCT experts who reached consensus for reference. Students received feedback between time points. Eventually, variance in OCT was smaller in images of diseased tissue than in images of normal vulvar tissue ...
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    2. Optical coherence tomography accurately identifies patients with penile (pre) malignant lesions: A single center prospective study

      Optical coherence tomography accurately identifies patients with penile (pre) malignant lesions: A single center prospective study
      Introduction: Currently, (multiple) biopsies are taken to obtain histopathological diagnosis of suspicious lesions of the penile skin. Optical coherence tomography (OCT) provides noninvasive in vivo images from which epidermal layer thickness and attenuation coefficient (m oct ) can be quantified. We hypothesize that qualitative (image assessment) and quantitative (epidermal layer thickness and attenuation coefficient, m oct ) analysis of penile skin with OCT is possible and may differentiate benign penile tissue from ...
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    3. Functional optical coherence tomography of pigmented lesions

      Functional optical coherence tomography of pigmented lesions
      Background Cutaneous melanomas are diagnosed worldwide in 231 130 patients per year. The sensitivity and specificity of melanoma diagnosis expresses the need for an additional diagnostic method. Optical coherence tomography (OCT) has shown that it allows morphological (qualitative) description of image features and quantitative analysis of pathology related light scattering by means of the attenuation coefficient ( oct ). Objective We hypothesize that OCT images of nevi will differ qualitatively and quantitatively ...
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    4. Functional optical coherence tomography of pigmented lesions

      Functional optical coherence tomography of pigmented lesions
      Background Cutaneous melanomas are diagnosed worldwide in 231 130 patients per year. The sensitivity and specificity of melanoma diagnosis expresses the need for an additional diagnostic method. Optical coherence tomography (OCT) has shown that it allows morphological (qualitative) description of image features and quantitative analysis of pathology related light scattering by means of the attenuation coefficient ( oct ). Objective We hypothesize that OCT images of nevi will differ qualitatively and quantitatively ...
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    5. Optical biopsy of epithelial cancers by optical coherence tomography (OCT)

      Optical biopsy of epithelial cancers by optical coherence tomography (OCT)
      Optical coherence tomography (OCT) is an optical technique that measures the backscattering of near-infrared light by tissue. OCT yields in 2D and 3D images at micrometer-scale resolution, thus providing optical biopsies, approaching the resolution of histopathological imaging. The technique has shown to allow in vivo differentiation between benign and malignant epithelial tissue, through qualitative assessment of OCT images, as well as by quantitative evaluation, e.g., functional OCT. This study ...
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    6. Optical coherence tomography in vulvar intraepithelial neoplasia

      Optical coherence tomography in vulvar intraepithelial neoplasia
      Vulvar squamous cell carcinoma (VSCC) is a gynecological cancer with an incidence of two to three per 100,000 women. VSCC arises from vulvar intraepithelial neoplasia (VIN), which is diagnosed through painful punch biopsy. In this study, optical coherence tomography (OCT) is used to differentiate between normal and VIN tissue. We hypothesize that (a) epidermal layer thickness measured in OCT images is different in normal tissue and VIN, and (b ...
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    7. Comparison of retinal nerve fiber layer thickness measurements by spectral-domain optical coherence tomography systems using a phantom eye model

      Comparison of retinal nerve fiber layer thickness measurements by spectral-domain optical coherence tomography systems using a phantom eye model
      To quantify differences in nerve fiber layer thickness measurements by various spectral-domain optical coherence tomography (SD-OCT) systems, we developed a phantom eye model. We tested twelve SD-OCT systems of four manufacturers. All systems combined overestimated the 49 m thick phantom RNFL thickness on average by 18 m. Within brands, thickness measurements differed statistically significant for one Topcon, one RTVue and one Cirrus. Between brands, thickness determined with RTVue and Topcon ...
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    8. Differentiation between normal renal tissue and renal tumours using functional optical coherence tomography: a phase I in vivo human study

      Differentiation between normal renal tissue and renal tumours using functional optical coherence tomography: a phase I in vivo human study
      ...msterdam, Amsterdam, the Netherlands 4. ^4 Mira Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, the Netherlands 1. ^† Both authors contributed equally to this paper. ^*Kurdo ...
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    9. Advanced Diagnostics in Renal Mass Using Optical Coherence Tomography: A Preliminary Report

      Advanced Diagnostics in Renal Mass Using Optical Coherence Tomography: A Preliminary Report
      Objective: To avoid unnecessary surgical treatment of small renal masses (≤4cm), a more accurate diagnostic method would be desirable since radiological differentiation between malignant and benign is difficult and nondiagnostic biopsies account from 9% to 37%. Optical coherence tomography (OCT) measures backscattered light versus depth, with an attenuation coefficient (μt) that may vary among different histological types. We hypothesize that quantitative measurements of μt using OCT can differentiate between normal ...
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    10. Quantitative measurement of attenuation coefficients of bladder biopsies using optical coherence tomography for grading urothelial carcinoma of the bladder

      Quantitative measurement of attenuation coefficients of bladder biopsies using optical coherence tomography for grading urothelial carcinoma of the bladder
      ...Medical Center, Department of Urology, P. O. Box 22660, 1100 DD Amsterdam, The Netherlands Ton G. van Leeuwen University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Biomedical Photonic ...
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    11. Optical phantoms of varying geometry based on thin building blocks with controlled optical properties

      Optical phantoms of varying geometry based on thin building blocks with controlled optical properties
      ...Academic Medical Center, Department of Biomedical Engineering and Physics, Amsterdam, 1100 DE Netherlands and University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Biomedical Photonic Ima...
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  2. Organizations in the News

    1. (11 articles) Academic Medical Center at the University of Amsterdam
    2. (1 articles) VU University Amsterdam
  3. People in the News

    1. (12 articles) Ton G. van Leeuwen
    2. (10 articles) Dirk J. Faber
    3. (3 articles) Jean J. M. C. H. de la Rosette
    4. (2 articles) Evelyne C. C. Cauberg
    5. (2 articles) Roy de Kinkelder
    6. (1 articles) Theo M. de Reijke
    7. (1 articles) Mike Visser
    8. (1 articles) Frank D. Verbraak
  4. OCT Companies in the News

    1. (2 articles) Topcon Medical Systems
    2. (1 articles) Optovue
    3. (1 articles) Santec
    4. (1 articles) Carl Zeiss Meditec
    5. (1 articles) Heidelberg Engineering