1. High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye

      High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye
      This study reports the development of prototype swept-source optical coherence tomography (SS-OCT) technology for imaging the anterior eye. Advances in vertical-cavity surface-emitting laser (VCSEL) light sources, signal processing, optics and mechanical designs, enable a unique combination of high speed, long range, and deep penetration that addresses the challenges of anterior eye imaging. We demonstrate SS-OCT with a 325 kHz A-scan rate, 12.2 m axial resolution (in air), and 15 ...
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    2. Historic Effort to 'End Blindness" Marks a Major Milestone with Leading Scientist Recognized for Pioneering Work at VIP Ceremony Featuring Tribute To Ruth Bader Ginsburg

      Historic Effort to 'End Blindness" Marks a Major Milestone with Leading Scientist Recognized for Pioneering Work at VIP Ceremony Featuring Tribute To Ruth Bader Ginsburg
      .... Eric Swanson, Department of Electrical Engineering and Computer Science Research Laboratory of Electronics, Massachusetts Institute of Technology Dr. Zhigang He, Boston Children’s Hospital F.M. Kirby Neurobiology Cente...
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    3. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

      Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
      Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT makes it very sensitive to the pulsatile bulk motion noise in the axial direction. To overcome this limitation, we developed split-spectrum amplitude-decorrelation angiography (SSADA) to improve the signal-to-noise ratio (SNR) of flow detection. The full OCT spectrum was split into several narrower ...
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    4. Application of Corneal Optical Coherence Tomography Angiography for Assessment of Vessel Depth in Corneal Neovascularization

      Application of Corneal Optical Coherence Tomography Angiography for Assessment of Vessel Depth in Corneal Neovascularization
      Purpose: To map and measure the depths of corneal neovascularization (NV) using 3-dimensional optical coherence tomography angiography (OCTA) at 2 different wavelengths. Methods: Corneal NV of varying severity, distribution, and underlying etiology was examined. Average NV depth and vessel density were measured using 840-nm spectral-domain OCTA and 1050-nm swept-source OCTA. The OCTA results were compared with clinical slit-lamp estimation of NV depth. Results: Twelve eyes with corneal NV from 12 ...
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    5. "Nobel prize for engineering sciences" goes to MedUni Vienna researchers

      "Nobel prize for engineering sciences" goes to MedUni Vienna researchers
      Christoph Hitzenberger and Adolf Fercher from MedUni Vienna have been awarded this years Fritz J. and Dolores H. Russ Prize. The prize is awarded by the United States National Academy of Engineering (NAE) for technological developments that "have had a significant impact on society and have helped to improve human well-being". The two researchers from Vienna played a major role in the development of Optical Coherence Tomography (OCT), an examination ...
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    6. Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors

      Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors
      Purpose To evaluate tumor vasculature with optical coherence tomography angiography (OCTA) in malignant iris melanomas and benign iris lesions. Design Cross-sectional observational clinical study. Participants Patients with iris lesions and healthy volunteers. Methods Eyes were imaged using OCTA systems operating at 1050- and 840-nm wavelengths. Three-dimensional OCTA scans were acquired. Iris melanoma patients treated with radiation therapy were imaged again after I-125 plaque brachytherapy at 6 and 18 months. Main ...
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    7. OCT - catching macular degeneration before vision loss

      OCT - catching macular degeneration before vision loss
      Growing old leads to a growing number of health problems, including those that challenge our ability to see. Age-related macular degeneration (AMD) is a disease that -- until recently -- robbed the elderly of the ability to read, drive and see the faces of their loved ones. Thanks to the invention of OCT, doctors can catch the disease before vision is lost. And with the aid of new drugs, AMD can be ...
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    8. Foreword: 25 Years of Optical Coherence Tomography

      Foreword: 25 Years of Optical Coherence Tomography
      This special issue commemorates the 25th anniversary of the development of optical coherence tomography (OCT). OCT has had a transformative impact in the field of ophthalmology and vision research, contributing to fundamental understanding of disease pathogenesis, drug discovery and development, and everyday clinical decision making in all ophthalmic subspecialties. The role of OCT in research and clinical care continues to accelerate, as judged by the cumulative number of publications in ...
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    9. Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye

      Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye
      ...3. ^cDepartment of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139 1. Edited by Morton Goldberg, The Johns Hopkins W...
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    10. Postprocessing algorithms to minimize fixed-pattern artifact and reduce trigger jitter in swept source optical coherence tomography

      Postprocessing algorithms to minimize fixed-pattern artifact and reduce trigger jitter in swept source optical coherence tomography
      ...on, USA ^2Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA ^*Corresponding author: liga@ohsu.edu ...
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    11. Clinical Guide to Angio-OCT (Non Invasive, Dyeless OCT Angiography) (Textbook)

      Clinical Guide to Angio-OCT (Non Invasive, Dyeless OCT Angiography)  (Textbook)
      The book discusses the clinical possibilities of Angio-OCT. Most imaging in the book (77 figures in Chapters 5, 7.1 and 10) has been performed with XR-Avanti Optovue SD-OCT device using SSADA algorithm. A few figures in chapters 3, 7.2 and 8 have been performed with a swept source OCT prototype using SSADA algorithm. Another technique is described in chapter 11, using ultrahigh speed, SS-OCT and its applications to ...
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    12. Optical Coherence Tomography Angiography of Optic Disc Perfusion in Glaucoma

      Optical Coherence Tomography Angiography of Optic Disc Perfusion in Glaucoma
      ...liations * Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts , PhD , David Huang x David Huang Search for a...
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    13. Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis

      Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis
      .... ^4Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 5. ^5Pattern Recognition Lab and Scho...
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    14. Optical Coherence Tomography Angiography of Optic Disc Perfusion in Glaucoma

      Optical Coherence Tomography Angiography of Optic Disc Perfusion in Glaucoma
      ...liations + Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts , * David Huang, MD, PhD Affiliations + Casey ...
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    15. En Face OCT Imaging of the Eye - Special Interest Group for the 2014 ARVO Annual Meeting May 2014

      En Face OCT Imaging of the Eye - Special Interest Group  for the 2014 ARVO Annual Meeting May 2014
      The Association for Research in Vision and Ophthalmology (ARVO)has approved a new Special Interest Group (SIG) for the 2014 ARVO Annual Meeting, May 4-8, 2014, in Orlando, Florida. The SIG is titled: En Face OCT imaging of the Eye SIG, Session Number: 355. The Organizer is Andre Romano and includes the following speakers: David Huang, James Fujimoto, Philip Rosenfeld. Bruno Lumbroso, Gabriel Coscas, Min Wang, Richard Rosen. More can ...
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    16. ARVO Champalimaud Award Lecture Videos By James G. Fujimoto and David R. Williams

      ARVO Champalimaud Award Lecture Videos By James G. Fujimoto and David R. Williams
      The 2012 Antnio Champalimaud Vision Award recognized the development of two novel approaches to visualising the living human retina in health and disease: OCT and adaptive optics. The award citation for OCT states, "Optical Coherence Tomography, or OCT, was developed by merging interferometric methodologies with insights for their clinical ocular applicantion by a multidisciplinary effort of engineers, scientists, and physicians accomplished by James Fujimoto, Eric Swanson, David Huang, Carmen Puliafito ...
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    17. Champalimaud Vision Award 2012 Highlights

      Champalimaud Vision Award 2012 Highlights
      Champalimaud Vision Award 2012 Highlights Carmen A. Puliafito, Dean of the Keck School of Medicine of USC, is honored along with James Fujimoto, Eric A. Swanson, David Huang and Joel S. Schuman with the prestigious 2012 Champalimaud Vision Award on Sept. 14 in Lisbon, Portugal. The team received the award for the development of Optical Coherence Tomography (OCT), a technology that has revolutionized the diagnosis and treatment of patients with ...
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      Jobs & Studentships, Student Theses, Textbooks
  2. Organizations in the News

    1. (39 articles) Oregon Health & Science University
    2. (16 articles) University of Southern California
    3. (11 articles) University of Pittsburgh
    4. (11 articles) Tufts University
    5. (7 articles) University of Erlangen
    6. (6 articles) University of Miami
    7. (5 articles) Medical University of Vienna
    8. (4 articles) Harvard University
    9. (3 articles) National Institutes of Health
    10. (3 articles) Massachusetts Eye and Ear Infirmary
    11. (3 articles) Baylor College of Medicine
    12. (2 articles) National Eye Institute
  3. OCT Companies in the News

    1. (9 articles) Thorlabs
    2. (7 articles) Visionix
    3. (4 articles) Carl Zeiss Meditec
    4. (3 articles) Abbott
    5. (2 articles) NinePoint Medical
    6. (1 articles) Optopol Technology
    7. (1 articles) Topcon Medical Systems
    8. (1 articles) Praevium Research
    9. (1 articles) Leica
    10. (1 articles) Heidelberg Engineering
    11. (1 articles) Tomey Corporation
    12. (1 articles) Optos