1. Articles mentioning both Bernhard Baumann and Ursula Schmidt-Erfurth

    1-24 of 27 1 2 »
    1. IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY

      IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To examine the involvement of the retinal pigment epithelium (RPE) in the presence of vitelliform macular lesions (VML) in Best vitelliform macular dystrophy (BVMD), autosomal recessive bestrophinopathy, and adult-onset vitelliform macular degeneration using polarization-sensitive optical coherence tomography (PS-OCT). Methods: A total of 35 eyes of 18 patients were imaged using a PS-OCT system and blue light fundus autofluorescence imaging. Pathogenic mutations in the BEST1 gene, 3 of which were ...
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    2. Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics

      Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics
      The purpose of this work is to investigate the benefits of adaptive optics (AO) technology for optical coherence tomography angiography (OCTA). OCTA has shown great potential in non-invasively enhancing the contrast of vessels and small capillaries. Especially the capability of the technique to visualize capillaries with a lateral extension that is below the transverse resolution of the system opens unique opportunities in diagnosing retinal vascular diseases. However, there are some ...
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    3. Automated Identification and Quantification of Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration Using Polarization-Sensitive OCT

      Automated Identification and Quantification of Subretinal Fibrosis in Neovascular Age-Related Macular Degeneration Using Polarization-Sensitive OCT
      Purpose : To identify and quantify subretinal fibrosis in eyes with advanced neovascular age-related macular degeneration (nAMD) using polarization-sensitive optical coherence tomography (PS-OCT). Methods : Eyes of patients with subretinal fibrosis secondary to nAMD were included in this case series. All patients underwent a complete ophthalmic examination to clearly identify advanced nAMD lesions with fibrosis. Examinations of PS-OCT were performed using a novel system with an integrated eye tracker. Areas of fibrosis ...
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    4. Retinal Pigment Epithelial Features in Central Serous Chorioretinopathy Identified by Polarization-Sensitive Optical Coherence Tomography

      Retinal Pigment Epithelial Features in Central Serous Chorioretinopathy Identified by Polarization-Sensitive Optical Coherence Tomography
      Purpose : To determine the subclinical RPE lesions detected by tissue selective polarization-sensitive optical coherence tomography (PS-OCT) in eyes with central serous chorioretinopathy (CSC) and to compare PS-OCT findings to current imaging standards. Methods : In this prospective observational case series, individuals with unilateral or bilateral active CSC were imaged using PS-OCT at baseline and after resolution of serous retinal detachment. Features seen on PS-OCT were compared with corresponding lesions as seen ...
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    5. Spectral degree of polarization uniformity for polarization-sensitive OCT

      Spectral degree of polarization uniformity for polarization-sensitive OCT
      Depolarization of light can be measured by polarization-sensitive optical coherence tomography (PS-OCT) and has been used to improve tissue discrimination as well as segmentation of pigmented structures. Most approaches to depolarization assessment for PS-OCT such as the degree of polarization uniformity (DOPU) rely on measuring the uniformity of polarization states using spatial evaluation kernels. In this article, we present a different approach which exploits the spectral dimension. We introduce the ...
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    6. Polarization-Sensitive Optical Coherence Tomography and Conventional Retinal Imaging Strategies in Assessing Foveal Integrity in Geographic Atrophy

      Polarization-Sensitive Optical Coherence Tomography and Conventional Retinal Imaging Strategies in Assessing Foveal Integrity in Geographic Atrophy
      Purpose : To compare current imaging methods with respect to their ability to detect the condition of the fovea in patients with geographic atrophy (GA). Methods : The retinas of 176 eyes with GA were imaged using two spectral-domain optical coherence tomography (SD-OCT) systems, Cirrus HD-OCT and Spectralis HRA+OCT, and fundus autofluorescence (FAF) and infrared imaging (IR) was used in the scanning laser ophthalmoscope (SLO) mode. Polarization-sensitive OCT (PS-OCT), which selectively ...
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    7. Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD

      Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD
      Background/aims To examine the reproducibility of lesion dimensions of the retinal pigment epithelium (RPE) in neovascular age-related macular degeneration (AMD) with polarisation-sensitive optical coherence tomography (PS-OCT), specifically imaging the RPE. Methods Twenty-six patients (28 eyes) with neovascular AMD were included in this study, and examined by a PS-OCT prototype. Each patient was scanned five times at a 1-day visit. The PS-OCT B-scan located closest to the macular centre presenting ...
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    8. Identification of Drusen Characteristics in Age-related Macular Degeneration by Polarization-Sensitive Optical Coherence Tomography

      Identification of Drusen Characteristics in Age-related Macular Degeneration by Polarization-Sensitive Optical Coherence Tomography
      ...r articles by this author , Stefan Sacu x Stefan Sacu Search for articles by this author , Bernhard Baumann x Bernhard Baumann Search for articles by this author , Matthias Bolz x Matthias Bolz Search for articles by thi...
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    9. RETINAL PIGMENT EPITHELIUM FINDINGS IN PATIENTS WITH ALBINISM USING WIDE-FIELD POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY

      RETINAL PIGMENT EPITHELIUM FINDINGS IN PATIENTS WITH ALBINISM USING WIDE-FIELD POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To investigate pigmentation characteristics of the retinal pigment epithelium (RPE) in patients with albinism using wide-field polarization-sensitive optical coherence tomography compared with intensity-based spectral domain optical coherence tomography and fundus autofluorescence imaging. Methods: Five patients (10 eyes) with previously genetically diagnosed albinism and 5 healthy control subjects (10 eyes) were imaged by a wide-field polarization-sensitive optical coherence tomography system (scan angle: 40 x 40[degrees] on the retina), sensitive ...
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    10. Detection and Analysis of Hard Exudates by Polarization-Sensitive Optical Coherence Tomography in Patients with Diabetic Maculopathy

      Detection and Analysis of Hard Exudates by Polarization-Sensitive Optical Coherence Tomography in Patients with Diabetic Maculopathy
      Purpose: To image and analyze hard exudates (HE) and their precursors in patients with diabetic macular edema (DME) using polarization sensitive optical coherence tomography (PS-OCT). Methods: Twenty-two eyes of 16 patients with DME were imaged using color fundus photography (CF) and PS-OCT. In PS-OCT, HE were automatically detected based on their distinct polarization-scrambling qualities. CF images were manually graded for the presence of HE by two masked graders and correlated ...
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    11. Imaging Retinal Pigment Epithelial Proliferation Secondary to PASCAL Photocoagulation In Vivo by Polarization-sensitive Optical Coherence Tomography

      Imaging Retinal Pigment Epithelial Proliferation Secondary to PASCAL Photocoagulation In Vivo by Polarization-sensitive Optical Coherence Tomography
      ...ns + Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria , * Ursula Schmidt-Erfurth Affiliations + Department of Ophthalmology, Medical University of Vienna, Vienna, Austr...
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    12. Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques

      Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques
      Purpose: To investigate the reproducibility of automated lesion size detection in patients with geographic atrophy (GA) using polarization-sensitive spectral domain-OCT (PS-OCT) and to compare findings with scanning laser ophthalmoscopy (SLO), fundus autofluorescence (FAF), and intensity based SD-OCT. Methods: 29 eyes of 22 patients with GA were examined by PS-OCT, selectively identifying the retinal pigment epithelium (RPE). A novel segmentation algorithm was applied, automatically detecting and quantifying areas of RPE atrophy ...
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    13. Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology

      Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology
      We present a novel spectral domain polarization sensitive OCT system (PS-OCT) that operates at an A-scan rate of 70 kHz and supports scan angles of up to 40° × 40°. The high-speed imaging allows the acquisition of up to 1024 × 250 A-scans per 3D scan, which, together with the large field of view, considerably increases the informative value of the images. To demonstrate the excellent performance of the new PS-OCT system ...
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    14. Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization

      Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization
      Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of OCT. In addition to imaging based on tissue reflectivity, PS-OCT also enables depth-resolved mapping of sample polarization properties such as phase-retardation, birefringent axis orientation, Stokes vectors, and degree of polarization uniformity (DOPU). In this study, PS-OCT was used to investigate the polarization properties of melanin. In-vitro measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization ...
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    15. Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography

      Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography
      Purpose: Idiopathic juxtafoveal telangiectasia (IJT) is characteristically associated with pigmentary changes. Polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) enables imaging of the retinal pigment epithelium (RPE) and similar melanin-containing structures based on specific polarization properties. This study examined IJT with the latest-generation SD-OCT and PS-SD-OCT, identifying pathophysiologically relevant characteristics of the retinal layers and RPE. Methods: Twenty-two eyes of 12 patients with IJT were examined by PS-SD-OCT, with special focus on ...
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    16. Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography

      Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography
      Purpose: To estimate the potential of polarization-sensitive optical coherence tomography (PS-OCT) for quantitative assessment of drusen in patients with early age-related macular degeneration (AMD). Methods: Fifteen eyes of thirteen patients presenting drusen consistent with AREDS 2 and 3 classification were examined ophthalmoscopically, followed by fundus photography, autofluorescence imaging and three-dimensional scanning using a PS-OCT. For the automated evaluation of drusen location, area and volume, a novel segmentation algorithm was developed ...
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    17. Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography

      Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography
      ..., Währinger Straße 13, A–1090 Vienna, Austria Christopher Schütze, Ferdinand Schlanitz, Christian Ahlers, and Ursula Schmidt-Erfurth Medical University of Vienna, Department of Ophthalmology, Währinger Gürtel 18-20, A–10...
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    18. Method For Determining Exudates In The Retina

      Method For Determining Exudates In The Retina
      The present invention relates to a method for detecting exudates and/or micro-exudates in the retina of an eye by imaging said retina with a polarisation sensitive optical coherence tomography (OCT) technique comprising the steps of a) illuminating the retina of said eye with light produced by a polarisation sensitive optical coherence tomography light source, b) scanning the retina with said light and collecting the reflection light or backscattered light ...
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    19. Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization sensitive optical coherence tomography

      ...Isabelle Golbaz,^4 Franz Prager,^5 Christopher Schütze,^6 Bernhard Baumann,^7 Christoph Hitzenberger,^8 and Ursula Schmidt-Erfurth^9 ^^1Department of Ophthalmology, Medival University Vienna, 1090 Vienna, Austria^ ^2Ce...
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    20. Quantitative measurement of the degree of polarization uniformity of light backscattered by retinal layers by polarization sensitive OCT

      We report on an extension of our previously presented polarization sensitive optical coherence tomography (PS-OCT) technique towards quantitative measurements and imaging of depolarization of light backscattered by the various layers of the human ocular fundus in vivo. We use a state of the art spec ... [Proc. SPIE 7168, 716814 (2009)] published Tue Feb 24, 2009.
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    21. 1-24 of 27 1 2 »
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  3. People in the News

    1. (27 articles) Michael Pircher
    2. (25 articles) Christoph K. Hitzenberger
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