1. Articles mentioning both Azienda Ospedaliera San Paolo and Giulio Guagliumi

    1-11 of 11
    1. Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)

      Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)
      Objectives The purpose of this study was to assess neoatherosclerosis in a registry of prospectively enrolled patients presenting with stent thrombosis using optical coherence tomography . Background In-stent neoatherosclerosis was recently identified as a novel disease manifestation of atherosclerosis after coronary stent implantation. Methods Angiography and intravascular optical coherence tomography were used to investigate etiologic factors of neoatherosclerosis in patients presenting with stent thrombosis 1 year after implantation (very late stent ...
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    2. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium
      Background Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed ...
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    3. Suboptimal agreement between optical coherence tomography and near-infrared spectroscopy for identification of lipid-laden plaque

      Suboptimal agreement between optical coherence tomography and near-infrared spectroscopy for identification of lipid-laden plaque
      Recently developed intracoronary imaging techniques allow real-time, in vivo identification of lipid in atherosclerotic plaques. Optical coherence tomography (OCT), a light-based imaging technique with high axial resolution (10-20 m), identifies lipid-laden plaques as signal-poor regions with diffuse borders. A validation study performed versus histopathology confirmed the high sensitivity (90% to 94%) and specificity (90% to 92%) of OCT to identify lipid-laden plaques 1 . Near-infrared spectroscopy (NIRS) detects lipid-laden plaque by ...
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    4. The OPTIS Integrated System: real-time, co-registration of angiography and optical coherence tomography

      The OPTIS Integrated System: real-time, co-registration of angiography and optical coherence tomography
      The efficacy of an IVUS-guided stent implantation strategy to improve acute results and clinical outcome has been described previously. OCT is another technique which allows high-resolution intracoronary imaging. However, the use of invasive imaging modalities to guide PCI has, as yet, played a limited role in current clinical practice. This may be partly explained by the expertise required for interpretation and clinical decision making. We present a novel technology which ...
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    5. Optical Coherence Tomography for Online Guidance of Complex Coronary Interventions

      Optical Coherence Tomography for Online Guidance of Complex Coronary Interventions
      Decision making on lesion preparation and stent/scaffold optimization are cornerstones of patient outcome. Intravascular imaging recently emerged as a critical modality to achieve better results of stent/scaffold implantation and superior clinical outcomes compared with coronary angiography alone. Optical coherence tomography (OCT), a light-based intravascular imaging modality with high frame rate in acquisition and very high speed pullback, can interrogate the target vessel in a couple of seconds, and ...
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    6. Impact of Culprit Plaque and Atherothrombotic Components on Incomplete Stent Apposition in Patients With ST-Elevation Myocardial Infarction Treated With Everolimus-Eluting Stents – An OCTAVIA Substudy –

      Impact of Culprit Plaque and Atherothrombotic Components on Incomplete Stent Apposition in Patients With ST-Elevation Myocardial Infarction Treated With Everolimus-Eluting Stents – An OCTAVIA Substudy –
      Background: The role of culprit plaque and related atherothrombotic components on incomplete stent apposition (ISA) occurrence after primary percutaneous coronary intervention (p-PCI) is unknown. Methods and Results: ST-segment elevation myocardial infarction (STEMI) patients undergoing p-PCI with an everolimus-eluting stent were prospectively investigated with optical coherence tomography (OCT) of the infarct-related artery before, after stenting and at 9 months. OCT data, aspirated thrombus and serum inflammatory biomarkers were analyzed. 114 patients ...
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    7. Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction : Results of the OCTAVIA (Optical Coherence Tomography Assessment of Gender Diversity in Primary Angiop

      Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction : Results of the OCTAVIA (Optical Coherence Tomography Assessment of Gender Diversity in Primary Angiop
      Objectives This study sought to assess in vivo sex differences in the pathophysiology of ST-segment elevation myocardial infarction (STEMI) and vascular response to primary percutaneous coronary intervention (PCI). Background There is no consensus on whether differences in the pathophysiology of STEMI and response to primary PCI between women and men reflect biological factors as opposed to differences in age. Methods In this prospective, multicenter study, 140 age-matched men and women ...
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    8. The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging

      The impact of an eccentric intravascular ImageWire during coronary optical coherence tomography imaging
      Optical Coherence Tomography (OCT) provides high-resolution imaging which enables characterisation of atherosclerosis and vascular response to injury, but to ensure optimal analysis, one must realise potential sources of image distortion. We designed a series of analysesl, using coronary stents as a model, to investigate the influence of wire position on OCT-derived vascular images.
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    9. Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations

      Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations
      Aims: We sought to evaluate the vascular response of stent struts deployed in bifurcation segments using optical coherence tomography (OCT). Conclusions: This study demonstrates a variable patter of strut coverage in the bifurcation among stent technologies, with a high percentage of PES floating struts remaining uncovered at 6-month follow-up.
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    10. Assessment of Heterogeneity of Strut-Level Neointima Hyperplasia After Stent Implantation by Optical Coherence Tomography

      Background: Optical coherence tomography (OCT) permits a highly accurate NIH assessment at each strut level within a cross-section. The aim of this study is to evaluate heterogeneity of NIH among different stents. Methods: Patients enrolled in ODESSA were assessed. ODESSA was a prospective randomized trial designed to evaluate strut coverage of overlapped (OLP) vs. non-OLP stent segments for the treatment of de-novo, native coronary artery stenosis with four different stent ...
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    11. Unhealed Plaque Ruptures After Stenting in Acute Myocardial Infarction Assessed by Intracoronary Optical Coherence Tomography: Incidence, Predictors, and Clinical Implication

      Backgrounds: Non healing after stenting a ruptured thin capped fibroatheroma in acute myocardial infarction (AMI) has been suggested to be a possible cause of late stent thrombosis. Optical coherence tomography (OCT) provides detailed information of ruptured plaques and stent strut coverage. We used OCT to assess the incidence, predictors, and implications of residual plaque rupture after stenting in AMI. Methods: The HORIZONS-AMI trial was a prospective, multicenter, dual arm factorial ...
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  2. Organizations in the News

    1. (5 articles) Case Western Reserve University
    2. (4 articles) Ospedali Riuniti di Bergamo
    3. (2 articles) Ludwig Maximilian University of Munich
    4. (2 articles) Sapienza University of Rome
    5. (2 articles) University of Bologna
    6. (2 articles) K. U. Leuven
    7. (2 articles) University of Catania
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    10. (1 articles) Erasmus University
    11. (1 articles) Cardiovascular Research Foundation
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  3. People in the News

    1. (8 articles) Vasile Sirbu
    2. (5 articles) Marco A. Costa
    3. (5 articles) Giuseppe Musumeci
    4. (4 articles) Hiram G. Bezerra
    5. (2 articles) Giuseppe Biondi-Zoccai
    6. (2 articles) Tom Adriaenssens
    7. (2 articles) Michael Joner
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    9. (2 articles) Kenichi Komukai
    10. (2 articles) Walter Desmet
    11. (2 articles) Takashi Kubo
    12. (2 articles) Orazio Valsecchi
  4. OCT Companies in the News

    1. (3 articles) St. Jude Medical
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