1. Articles mentioning both Aquyre Biosciences and ESPCI ParisTech

    1-24 of 28 1 2 »
    1. Full-field optical coherence tomography: novel imaging technique for extemporaneous high-resolution analysis of mucosal architecture in human gut biopsies

      Full-field optical coherence tomography: novel imaging technique for extemporaneous high-resolution analysis of mucosal architecture in human gut biopsies
      Full-field optical coherence tomography (FFOCT) is an imaging technique of biological tissue based on tissue light reflectance analysis. We evaluated the feasibility of imaging fresh digestive mucosal biopsies after a quick mounting procedure (5min) using two distinct modalities of FFOCT. In static FFOCT mode, we gained high-resolution images of general gut tissue-specific architecture, such as oesophageal papillae, gastric pits, duodenal villi and colonic crypts. In dynamic FFOCT mode, we imaged ...
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    2. Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT

      Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT
      We describe recent technological progress in multimodal en face full-field optical coherence tomography that has allowed detection of slow and fast dynamic processes in the eye. We show that by combining static, dynamic and fluorescence contrasts we can achieve label-free high-resolution imaging of the retina and anterior eye with temporal resolution from milliseconds to several hours, allowing us to probe biological activity at subcellular scales inside 3D bulk tissue. Our ...
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    3. In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography

      In vivo imaging through the entire thickness of human cornea by full-field optical coherence tomography
      Despite obvious improvements in visualization of the in vivo cornea through the faster imaging speeds and higher axial resolutions, cellular imaging stays unresolvable task for OCT, as en face viewing with a high lateral resolution is required. The latter is possible with FFOCT, a method that relies on a camera, moderate numerical aperture (NA) objectives and an incoherent light source to provide en face images with a micrometer-level resolution. Recently ...
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    4. Full-Field Optical Coherence Tomography as a Diagnosis Tool: Recent Progress with Multimodal Imaging

      Full-Field Optical Coherence Tomography as a Diagnosis Tool: Recent Progress with Multimodal Imaging
      Full-field optical coherence tomography (FF-OCT) is a variant of OCT that is able to register 2D en face views of scattering samples at a given depth. Thanks to its superior resolution, it can quickly reveal information similar to histology without the need to physically section the sample. Sensitivity and specificity levels of diagnosis performed with FF-OCT are 80% to 95% of the equivalent histological diagnosis performances and could therefore benefit ...
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    5. Appearance of the Retina With Full-Field Optical Coherence Tomography

      Appearance of the Retina With Full-Field Optical Coherence Tomography
      Purpose : To interpret full-field optical coherence tomography (FFOCT) images of ex vivo retina. Methods : Flatmounted retinas of human, primate, pig, sheep, rat, and mouse were imaged using FFOCT. To identify retinal ganglion and amacrine cells, fixed samples immunolabeled against Tuj1 and Brn3a or live samples labeled in vitro with green fluorescent protein (GFP) were analyzed by combining FFOCT, fluorescence confocal microscopy (FCM), and fluorescence-FFOCT. To investigate postmortem tissue changes, time ...
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    6. Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis

      Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis
      We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals signals linked with local activity of the endogenous scattering elements which can reveal cells where other OCT-based techniques fail or need exogenous contrast agents. We benefit from the micrometric transverse resolution of full field OCT to ...
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    7. High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography

      High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography
      Full-field optical coherence tomography (FF-OCT) is a powerful tool for nondestructive assessment of biological tissue, i.e., for the structural examination of tissue in depth at a cellular resolution. Mostly known as a microscopy device for ex vivo analysis, FF-OCT has also been adapted to endoscopy setups since it shows good potential for in situ cancer diagnosis and biopsy guidance. Nevertheless, all the attempts to perform endoscopic FF-OCT imaging did ...
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    8. Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas

      Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas
      Purpose : To evaluate the performance of a full-field optical coherence tomography (FF-OCT) system in the study of human donor and pathological corneas and assess its suitability for use in eye banks. Methods : Our study was carried out using an FF-OCT system developed for non-invasive imaging of tissue structures in depth with ultrahigh resolution (1m in all directions). Images were acquired from eight stored human donor corneas (either edematous or after ...
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    9. High resolution in-vivo imaging of skin with full field optical coherence tomography

      High resolution in-vivo imaging of skin with full field optical coherence tomography
      Full-field OCT (FFOCT) has the ability to provide en-face images with a very good axial sectioning as well as a very high transverse resolution (about 1 microns in all directions). Therefore it offers the possibility to visualize biological tissues with very high resolution both on the axial native view, and on vertical reconstructed sections. Here we investigated the potential dermatological applications of in-vivo skin imaging with FFOCT. A commercial FFOCT ...
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    10. Feature Of The Week: Feature Of The Week 1/26/14: ESPCI-ParisTech Investigates Full-Field Optical Coherence Tomograpy (FF-OCT) Shear Wave Elastography

      Feature Of The Week: Feature Of The Week 1/26/14: ESPCI-ParisTech Investigates Full-Field Optical Coherence Tomograpy (FF-OCT) Shear Wave Elastography
      ... ESPCI ParisTech.

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    11. 3D static elastography at the micrometer scale using Full Field OCT

      3D static elastography at the micrometer scale using Full Field OCT
      Full-Field OCT (FF-OCT) is able to image biological tissues in 3D with micrometer resolution. In this study we add elastographic contrast to the FF-OCT modality. By combining FF-OCT with elastography, we create a virtual palpation map at the micrometer scale. We present here a proof of concept on multi-layer phantoms and preliminary results on ex vivo biological samples such as porcine cornea, human breast tissues and rat heart. The 3D ...
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    12. Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography

      Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography
      A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of full-field optical coherence tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1 m resolution in 3D to a penetration depth of around 200 m. A 1 cm 2 specimen is scanned at a single depth and processed in about 5 min. This rapid imaging process is non-invasive ...
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    13. Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment

      Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment
      We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) was used to image human breast tissue and is evaluated to assess its ability to aid the pathologists management of intra-operative diagnoses. FF-OCT imaging safety was investigated and agreement between FF-OCT and routinely prepared histopathological images was evaluated. The compact setup used for this study provides 1 mm3 resolution and 200 mm imaging depth, and a ...
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    14. Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe

      Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe
      ...inal tracts.For more information see recent Article. Courtesy Anne Latrive from Langevin Institute, ESPCI and LLTech.    References1. Dubois and A.C. Boccara, “Full-field optical coherence tomography” in Optical cohe...
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    15. Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award

      Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award
      ...tructive 3D imaging of Stem Cell. http://www.lltechimaging.com/products-applications/products About LLTech LLTech is a privately owned company founded in 2007. LLTech vision is to become the leader in real time, safe,...
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    16. 1-24 of 28 1 2 »
      1. Categories

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          Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
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          Broadband Sources, Probes, Tunable Sources
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          Jobs & Studentships, Student Theses, Textbooks
      2. Organizations in the News

        1. (3 articles) National Institutes of Health
        2. (2 articles) Institute of Applied Physics
        3. (2 articles) UC Irvine
        4. (2 articles) University of Illinois at Urbana-Champaign
        5. (2 articles) University of Texas at Austin
        6. (2 articles) Case Western Reserve University
        7. (2 articles) Cornell University
        8. (2 articles) Nicolaus Copernicus University
        9. (2 articles) Massachusetts Institute of Technology
        10. (2 articles) Duke University
        11. (2 articles) Massachusetts General Hospital
        12. (2 articles) University of Pittsburgh
      3. OCT Companies in the News

        1. (2 articles) Solianis Monitoring AG
        2. (2 articles) Thorlabs
        3. (2 articles) Visionix
        4. (2 articles) Nidek
        5. (2 articles) Newton Photonics
        6. (2 articles) Topcon Medical Systems
        7. (2 articles) Terumo Corporation
        8. (2 articles) Tomey Corporation
        9. (2 articles) Physical Sciences Incorporated
        10. (2 articles) Optos
        11. (2 articles) Michelson Diagnostics
        12. (2 articles) Optiphase