1. Articles mentioning both Anton F. W. van der Steen and Evelyn Regar

    1-16 of 16
    1. EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging

      EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging
      Aims: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo . High optical attenuation coefficient t has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo , specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability ...
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    2. Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study

      Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study
      Lipid-core atherosclerotic plaques are associated with disease progression, procedural complications, and cardiac events. Coronary plaque lipid can be quantified in optical coherence tomography (OCT) pullbacks by measurement of lipid arcs and lipid lengths; parameters frequently used in clinical research, but labor intensive and subjective to analyse. In this study, we investigated the ability of quantitative attenuation, derived from intravascular OCT, to detect plaque lipid. Lipid cores are associated with a ...
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    3. Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy

      Heartbeat OCT and Motion-Free 3D In Vivo Coronary Artery Microscopy
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of coronary artery pathologies and interventions (1) . In contrast to the cross-sectional view, longitudinal sections and 3-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements (2) . We developed Heartbeat OCT, a new OCT method that achieves up to 4,000 frames/s imaging speed for isotropically ...
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    4. Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography

      Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of the coronary artery pathologies and interventions. In contrast to the cross-sectional view, longitudinal sections and three-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements. We developed Heartbeat OCT, a new OCT method that overcomes these issues. This study aims to demonstrate in vivo Heartbeat OCT ...
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    5. Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

      Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography
      Cardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging system that we called Heartbeat OCT, combining a fast Fourier Domain Mode Locked laser, fast pullback, and a micromotor actuated catheter, designed to examine a coronary vessel in less than one ...
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    6. Tiny Camera Sees Inside Blood Vessels

      Tiny Camera Sees Inside Blood Vessels
      Ahead of any surgical procedure, doctors try to learn as much as possible about the state of the organs they plan to operate on. A new camera developed in the Netherlands can now make that easier - giving surgeons an incredibly detailed look inside blood vessels, all the way to the patients heart. Blockages in coronary arteries, caused by the buildup of plaque, are the main cause of heart attacks. In ...
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    7. Effect of temperature and fixation on the optical properties of atherosclerotic tissue: a validation study of an ex-vivo whole heart cadaveric model

      Effect of temperature and fixation on the optical properties of atherosclerotic tissue: a validation study of an ex-vivo whole heart cadaveric model
      ...,^1 Stephen White,^2 Simon Scoltock,^2 Giovanni J Ughi,^4 Andreas Baumbach,^2 Antonius FW van der Steen,^1,^3 Evelyn Regar,^1 and Thomas W Johnson^2 ^1Department of Biomedical Engineering, Erasmus Medical Center, PO Bo...
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    8. Frequency domain multiplexing for speckle reduction in optical coherence tomography

      Frequency domain multiplexing for speckle reduction in optical coherence tomography
      Quantitative analysis of optical coherence tomography data can be strongly hampered by speckle. Here, we introduce a new method to reduce speckle, which leverages from Fourier-domain configurations and operates on individual axial scans. By subdividing the digitized spectrum into a number of distinct narrower windows, each with a different center frequency, several independent speckle patterns result. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The ...
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    9. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ...clinicians who use IVOCT and analyze IVOCT data Guillermo J. Tearney, MD, PhD, Writing Committee Co-Chair*,*, Evelyn Regar, MD, PhD, Writing Committee Co-Chair, Takashi Akasaka, MD, Writing Committee Co-Chair, Tom Adriae...
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    10. Wavelength multiplexing for FD-OCT speckle averaging

      Wavelength multiplexing for FD-OCT speckle averaging
      Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be ...
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    11. NIRS and IVUS for Characterization of Atherosclerosis in Patients Undergoing Coronary Angiography

      NIRS and IVUS for Characterization of Atherosclerosis in Patients Undergoing Coronary Angiography
      ..., RN^, Roberto Diletti, MD^, Joanna Wykrzykowska, MD^^,||, Robert-Jan van Geuns, MD, PhD^, Carl Schultz, MD^, Evelyn Regar, MD, PhD^, Henricus J. Duckers, MD, PhD^, Nicolas van Mieghem, MD^, Peter de Jaegere, MD, PhD^, S...
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    12. Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro

      Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro
      This study was performed to characterize coronary plaque types by optical coherence tomography (OCT) and intravascular ultrasound (IVUS) radiofrequency (RF) data analysis, and to investigate the possibility of error reduction by combining these techniques. Intracoronary imaging methods have greatly enhanced the diagnostic capabilities for the detection of high-risk atherosclerotic plaques. IVUS RF data analysis and OCT are two techniques focusing on plaque morphology and composition. Regions of interest were selected ...
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    13. Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

      Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography
      Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient mu(t) distinguishes different ...
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    14. 1-16 of 16
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  2. Organizations in the News

    1. (16 articles) Erasmus University
    2. (5 articles) Massachusetts General Hospital
    3. (4 articles) Delft University of Technology
    4. (4 articles) Harvard University
    5. (3 articles) Academic Medical Center at the University of Amsterdam
    6. (2 articles) University of Lübeck
    7. (2 articles) Ludwig Maximilian University of Munich
    8. (2 articles) Chinese Academy of Sciences
    9. (1 articles) Tohoku University
    10. (1 articles) Case Western Reserve University
    11. (1 articles) Massachusetts Institute of Technology
    12. (1 articles) K. U. Leuven
  3. People in the News

    1. (14 articles) Gijs van Soest
    2. (6 articles) Patrick W. Serruys
    3. (5 articles) Nieves Gonzalo
    4. (4 articles) Guillermo J. Tearney
    5. (4 articles) Heleen M. M. Van Beusekom
    6. (4 articles) Brett E. Bouma
    7. (4 articles) Hector M. Garcia-Garcia
    8. (3 articles) Tianshi Wang
    9. (3 articles) Tom Pfeiffer
    10. (3 articles) Geert Springeling
    11. (3 articles) Robert A. Huber
    12. (3 articles) Wolfgang Wieser
  4. OCT Companies in the News

    1. (2 articles) Abbot
    2. (1 articles) InfraReDx
    3. (1 articles) Optores