1. Articles mentioning both Alexander V. Bykov and University of Oulu

    1-17 of 17
    1. Noninvasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

      Noninvasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles
      The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive ...
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    2. Quantification of cell-free layer thickness and cell distribution of blood by optical coherence tomography

      Quantification of cell-free layer thickness and cell distribution of blood by optical coherence tomography
      A high-speed optical coherence tomography (OCT) with 1 - m axial resolution was applied to assess the thickness of a cell-free layer (CFL) and a spatial distribution of red blood cells (RBC) next to the microchannel wall. The experiments were performed in vitro in a plain glass microchannel with a width of 2 mm and height of 0.2 mm. RBCs were suspended in phosphate buffered saline solution at the hematocrit ...
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    3. Optical clearing of articular cartilage: a comparison of clearing agents

      Optical clearing of articular cartilage: a comparison of clearing agents
      Optical clearing technique was applied to the problem of OCT imaging of articular cartilage and subchondral bone. We show that optical clearing significantly enhances visualization of articular cartilage and cartilage-bone interface. The effect of different clearing agents was analyzed. For the clearing, iohexol solution and propylene glycol (PG) were used. Clearing was performed in vitro at room temperature by immersion method. Cylindrical osteochondral samples (d=4.8mm) were drilled from ...
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    4. Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage

      Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage
      Optical clearing is an effective method to reduce light scattering of biological tissues that provides significant enhancement of light penetration into the biological tissues making non-invasive diagnosis more feasible. In current report Optical Coherence Tomography (OCT) in conjunction with optical clearing is applied for assessment of deep cartilage layers and cartilage-bone interface. The solution of Iohexol in water has been used as an optical clearing agent. The cartilage-bone boundary becomes ...
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    5. Evaluation of Freshness of Soft Tissue Samples with Optical Coherence Tomography Assisted by Low Frequency Electric Field

      Evaluation of Freshness of Soft Tissue Samples with Optical Coherence Tomography Assisted by Low Frequency Electric Field
      We present an optical coherence tomography based methodology to determine freshness of soft tissue samples by evaluation of their interaction with low frequency electric field. Various biological tissues samples of different stages of freshness were exposed by low frequency electric current. The influence of the low frequency electric field on tissues was observed and quantified by the double correlation optical coherence tomography (dcOCT) approach developed in house. The quantitative evaluation ...
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    6. Determination of suspension viscosity from the flow velocity profile measured by Doppler Optical Coherence Tomography

      Determination of suspension viscosity from the flow velocity profile measured by Doppler Optical Coherence Tomography
      In this paper we present, for the first time to our knowledge, the experimental results for determining suspension viscosity in a capillary type viscometer from flow velocity profiles measured by Doppler Optical Coherence Tomography. The suspension of 0.3?m polystyrene microspheres in a glycerol-water solution was used as a model fluid. The viscosity of the suspension was controlled by glycerol concentration. The shear rate and the shear stress at ...
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    7. Experimental study of the multiple scattering effect on the flow velocity profiles measured in intralipid phantoms by DOCT

      Experimental study of the multiple scattering effect on the flow velocity profiles measured in intralipid phantoms by DOCT
      Abstract  Time domain Doppler Optical Coherence Tomography (DOCT) technique was applied to measure flow velocity profiles in highly scattering media. We analyzed the distortions of the measured velocity profiles of the 1% Intralipid solution flow embedded into the scattering medium at different embedding depths. For this purpose a tissue phantom consisting of a plain glass capillary (inner diameter 0.3 mm) embedded into a slab of Intralipid solution mimicking human ...
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    8. Multiple and dependent scattering effects in Doppler optical coherence tomography

      Multiple and dependent scattering effects in Doppler optical coherence tomography
      Doppler optical coherence tomography (OCT) is a technique to image tissue morphology and to measure flow in turbid media. In its most basic form, it is based on single (Mie) scattering. However, for highly scattering and dense media multiple and concentration dependent scattering can occur. For Intralipid solutions with varying scattering strength, the effect of multiple and dependent scattering on the OCT signal attenuation and Doppler flow is investigated. We ...
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    9. Doppler OCT imaging of cytoplasm shuttle flow in Physarum polycephalum

      The Doppler optical coherence tomography technique was applied to image the oscillatory dynamics of protoplasm in the strands of the plasmodium of slime mould Physarum polycephalum. Radial contractions of the gel-like walls of the strands and the velocity distributions in the sol-like endoplasm streaming along the plasmodial strands are imaged. The motility inhibitor effect of carbon dioxide on the cytoplasm shuttle flow and strand-wall contraction is shown. The optical attenuation ...
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    10. Monte Carlo simulation of the optical coherence Doppler tomography signals from blood flows in light scattering media: problem of flow velocity profile reconstruction

      Optical Coherence Tomography (OCT) and Optical Coherence Doppler Tomography (OCDT) signals from one and two plain flows of a non-aggregating particulate suspension mimicking blood embedded into a stationary light scattering medium (2% Intralipid solution) with optical properties close to those of human skin were simulated implementing the Monte Carlo method. The role of multiple scattering in the OCT signals was analyzed. The maximal visualization depths for OCT imaging of different ...
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    11. Effect of multiple scattering on the accuracy of velocity profile reconstruction from the Monte-Carlo simulated OCDT signal in a model of biological tissues

      Using the Monte-Carlo method we simulated the Optical Coherence Doppler Tomography (OCDT) signals at the wavelength of 1 = 822 nm from one and two plain flows of a non-aggregating particulate suspension mimicking blood embedded into a stationary light scattering medium (2% Intralipid solution) with optical properties close to those of human skin. The dependences of statistical characteristics such as mean value and standard deviation of the stochastic fluctuations of the ...
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    12. 1-17 of 17
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  2. Organizations in the News

    1. (8 articles) Moscow State University
    2. (2 articles) Academic Medical Center at the University of Amsterdam
    3. (1 articles) University of Otago
    4. (1 articles) University of Twente
    5. (1 articles) Saratov State University
  3. People in the News

    1. (9 articles) Risto A. Myllylä
    2. (8 articles) Alexander V. Priezzhev
    3. (6 articles) Janne Lauri
    4. (4 articles) Matti Kinnunen
    5. (3 articles) Valery V. Tuchin
    6. (3 articles) Igor V. Meglinski
    7. (2 articles) Mikhail Y. Kirillin
    8. (2 articles) Ton G. van Leeuwen
    9. (2 articles) Jeroen Kalkman
    10. (1 articles) Dirk J. Faber
    11. (1 articles) Tapio E. J. Fabritius