1. 1-13 of 13
    1. Comparative study of anterior segment measurement with Pentacam and anterior segment optical coherence tomography

      Comparative study of anterior segment measurement with Pentacam and anterior segment optical coherence tomography

      Objective: To evaluate the repeatability of central corneal thickness (CCT), anterior chamber volume (ACV), and central anterior chamber depth (CACD) measurements obtained using a Pentacam rotating Scheimpflug camera, and to examine their agreement with measurements obtained using an anterior segment optical coherence tomography (AS-OCT) imaging system.Design: Observational cross-sectional study.Participants: Fifty eyes from 50 healthy subjects were recruited.Methods: CCT, CACD, and ACV were measured. Subjects were re-examined twice within a week of the first measurements. Intrasession and intersession within-subject SD (Sw), precision (1.96 × Sw), coefficient of variation (CVw: 100 × Sw / overall mean), and intraclass correlation coefficient (ICC ...

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    2. Using retinal architecture to help characterize multiple sclerosis patients

      Using retinal architecture to help characterize multiple sclerosis patients

      Objective: We compared retinal nerve fibre layer (RNFL) thickness and visual function in a heterogeneous multiple sclerosis (MS) cohort to determine whether optical coherence tomography (OCT) may complement the existing methods used to characterize MS patients. Design: Cross-sectional cohort study. Participants: One hundred and ninety-three patients with optic neuritis (ON) as a clinically isolated syndrome (CIS) (n = 63), relapsing-remitting MS (RRMS) (n = 108), secondary progressive MS (SPMS) (n = 13), and primary progressive MS (PPMS) (n = 9). Methods: All patients underwent standardized ophthalmic, neurological, and OCT testing at a single academic institution. Results: RNFL values were reduced in PPMS (94.3 ...

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    3. Relation between blue-on-yellow perimetry and optical coherence tomography in normal tension glaucoma

      Relation between blue-on-yellow perimetry and optical coherence tomography in normal tension glaucoma
      Objective: To assess the relation between blue-on-yellow perimetry (B/YP) indices and optical coherence tomography (OCT) parameters in normal tension glaucoma (NTG) patients and to investigate the diagnostic ability of B/YP and OCT in discriminating NTG from normal eyes. Design: Cross-sectional study. Participants: Eighty normal subjects (80 eyes) and 80 NTG patients (80 eyes) were enrolled in the study. Methods: All patients underwent white-on-white perimetry, B/YP, and OCT measurement. The correlation between B/YP indices and OCT parameters was analyzed. The area of the receiver operating characteristic (ROC) curve was calculated to discriminate NTG patients from normal subjects ...
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    4. Progressive changes from idiopathic macular telangiectasia seen with spectral domain optical coherence tomography

      Progressive changes from idiopathic macular telangiectasia seen with spectral domain optical coherence tomography

      Idiopathic macular telangiectasia causes bilateral gradual vision loss, usually with an onset between 40 and 60 years of age. Diagnosis is made by clinical examination and fluorescein angiography (FA), which demonstrates late frame leakage from incompetent retinal vessels temporal to the fovea. In addition, parafoveal pigmentary changes are visible, particularly temporal to the fovea, and optical coherence tomography (OCT) often demonstrates hyporeflective spaces within the retina.

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    5. Spontaneous resolution of foveal cysts associated with X-linked retinoschisis as observed by optical coherence tomography

      Spontaneous resolution of foveal cysts associated with X-linked retinoschisis as observed by optical coherence tomography
      X-linked retinoschisis (XLRS) is an inherited disorder characterized by splitting of the retinal layer. There are no known effective therapeutic interventions for patients with XLRS. In recent years, however, the use of carbonic anhydrase inhibitors and vitrectomy have been reported to be effective in reducing foveal retinoschisis. We encountered a case of XLRS in which spontaneous regression was observed by means of optical coherence tomography (OCT). A 22-year-old male presented with a chief complaint of decreased visual acuity that had been present since childhood. The best-corrected visual acuity (BCVA) was 20/125, and refractive error was 2 D myopia OU ...
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      Mentions: Jung-Yeul Kim
    6. Usefulness of anterior segment optical coherence tomography in the demonstration of intralenticular foreign body in traumatic cataract

      Usefulness of anterior segment optical coherence tomography in the demonstration of intralenticular foreign body in traumatic cataract
      Usefulness of anterior segment optical coherence tomography in the demonstration of intralenticular foreign body in traumatic cataract. Penetrating injury with intraocular foreign body (IOFB) is a common condition presenting in emergency services. Most of the time, accurate ocular assessment may not be possible in these cases. We report a case of retained intralenticular foreign body with clinical features, anterior segment photograph, and anterior segment optical coherence tomography (OCT) scan.
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    7. Can preoperative anterior chamber angle width predict magnitude of intraocular pressure change after cataract surgery?

      Can preoperative anterior chamber angle width predict magnitude of intraocular pressure change after cataract surgery?
      Objective: To determine whether preoperative anterior chamber angle width, captured by anterior segment optical coherence tomography (AS-OCT), can be a predictor of intraocular pressure (IOP) change following cataract surgery. Design: Prospective comparative observational study. Participants: Fifty-three eyes of 53 patients awaiting cataract surgery were included. Methods: Measurement of anterior chamber angle width and IOP using AS-OCT and Goldmann’s applanation tonometry, respectively, were performed before and 6 months after phacoemulsification and intraocular lens implantation. Preoperative and postoperative measurements were compared using paired t test. The prediction rule defined success as ≥20% IOP reduction from the baseline preoperative IOP measurement. Multivariate ...
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    8. Anterior segment imaging using optical coherence tomography in atypical pigment dispersion syndrome

      Anterior segment imaging using optical coherence tomography in atypical pigment dispersion syndrome
      We describe the usefulness of anterior segment optical coherence tomography (OCT) for documenting an atypical case of pigment dispersion syndrome associated with unilateral dense annular pigmentation of the posterior lens capsule. A 56-year-old man reported a slowly decreasing visual acuity in the left eye. He denied a history of ocular problems. Visual acuity was 20/20 OD and 20/40 OS; intraocular pressure was 19 and 22 mm Hg in the 2 eyes, respectively. After pupil dilation, heavy annular pigment deposition on the posterior lens surface without lens opacity was observed by slit-beam biomicroscopy and retroillumination (Figs. 1A, 1B). Examination ...
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    9. Documentation of optic disc melanocytoma by spectral and time domain optical coherence tomography

      Documentation of optic disc melanocytoma by spectral and time domain optical coherence tomography

      Melanocytoma is a benign melanocytic lesion that usually occurs in the inferotemporal area of the optic nerve head.1 The uveal melanocytes emanating from the neural crest during embryogenesis are believed to be the cells of origin. These cells are present in the lamina choroidalis, the portion of the optic nerve adjacent to the choroid.2 The tumour is typically unilateral and stationary, and rarely undergoes a malignant transformation. The condition is usually asymptomatic except when the tumour undergoes extensive necrosis or malignant transformation, or is associated with the choroidal neovascular membrane.1,2 Optical coherence tomography (OCT) is increasingly ...

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    10. Comparison of retinal nerve fibre layer measurements from time domain and spectral domain optical coherence tomography systems

      Comparison of retinal nerve fibre layer measurements from time domain and spectral domain optical coherence tomography systems
      Objective: To compare retinal nerve fibre layer (RNFL) thickness measurements acquired using spectral domain (SD) and time domain (TD) optical coherence tomography (OCT) systems. Study Design: Prospective clinical study. Participants: Twenty eyes of 20 healthy volunteers. Methods: All patients underwent 3 sets of circular OCT scans around the optic disc using both a TD OCT system, and a new SD OCT system. RNFL thickness measures within each of 4 quadrants, as well as overall mean RNFL thickness, were compared. Bland-Altman plots were also used to assess agreement. Results: Using the RTVue-100, RNFL measurements in the superior quadrant were, on average ...
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    11. Nerve fibre layer thinning in patients with preclinical retinopathy

      Objective: To compare retinal nerve fibre layer thickness (RNFLT) obtained by optical coherence tomography (OCT) between patients with preclinical diabetic retinopathy (DR) and healthy subjects. Study Design:Cross-sectional study. Participants: Ninety-nine type I or II diabetic patients with no visible funduscopic retinal alteration and 77 healthy subjects were included in this study. Methods: All participants were evaluated for peripapillary RNFLT by Stratus OCT. In diabetic patients, levels of blood sugar and glycosylated hemoglobin were examined. Results: The mean RNFLT in diabetic patients and healthy subjects was significantly different (104.2 [SD 10.4] and 108.6 [SD 9.2] µm ...
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    12. Nerve fibre layer changes in highly myopic eyes by optical coherence tomography

      Objective: The purpose of this study was to investigate any correlations that may exist between retinal nerve fibre layer (RNFL) thickness and high myopia by optical coherence tomography (OCT). Design: Case-control study. Participants: Ten patients (20 eyes) with high myopia and 10 control patients (20 eyes) matched for age and sex were recruited from a database search of 1 vitreoretinal practice in Regina, Sask. Methods: The RNFL thickness of 10 highly myopic patients and 10 control patients matched for age and sex from a clinical practice was determined using the Stratus OCT. All 10 highly myopic patients selected for the ...
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    13. Discriminating ability of optical coherence tomography data in staging glaucomatous damage

      Objective: To evaluate the ability of retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) measurements, as determined by optical coherence tomography (OCT), to discriminate between normal eyesight and glaucoma and also among the different stages of glaucoma. Design: Observational cross-sectional study. Participants: Eighty-one controls and 213 glaucoma patients were enrolled in the study. Methods: The discriminating powers of OCT parameters for the detection of glaucoma and subgroups were compared by the area under the receiver operating characteristic (AUROC) curves. Results: The best RNFL thickness parameters for discriminating between early glaucoma and control eyes were inferior (0.74 ...
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    1-13 of 13
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