1. 49-72 of 1640 « 1 2 3 4 5 6 ... 67 68 69 »
    1. Optical coherence tomography confirms the pathomechanism of acute fluid misdirection syndrome

      Optical coherence tomography confirms the pathomechanism of acute fluid misdirection syndrome

      We have read the article by Anisimova et al. with great interest, and we believe that some discussion is required. 1 In this very original investigation, the authors have imaged the Berger's space with intraoperative optical coherence tomography to assess the risk factors for intraoperative complications during phacoemulsification. This study established evidence on migration of lens microfragments, triamcinolone, or cellular material into the Berger's space during cataract surgery. The discontinuity of both the lenticular zonules and Wieger's ligament attachment is presented as the key mechanism for developing fluid misdirection. 2,3 The authors use different terms, including ...

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    2. Evaluation Using Spectral-Domain Optical Coherence Tomography of the Effects of Malnutrition on Ocular Parameters in Pediatric Patients

      Evaluation Using Spectral-Domain Optical Coherence Tomography of the Effects of Malnutrition on Ocular Parameters in Pediatric Patients

      SIGNIFICANCE We determined decreases in choroidal thickness and retinal nerve fiber layer (RNFL) thickness in all quadrants. Our findings show that the choroid and RNFL are affected before the emergence of ocular symptoms in malnourished children. PURPOSE We aimed to determine whether the RNFL, a component of the neuronal structure, and the choroid, supplying the retina, are affected in children with malnutrition using spectral-domain optical coherence tomography. METHODS One hundred twenty-six malnourished patients without ocular symptoms, aged between 5 and 10 years, and 116 healthy children were included in the study. Age, sex, weight-for-age (WFA) z score, height-for-age z score ...

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    3. Efficacy of Swept-source Optical Coherence Tomography in Axial Length Measurement for Advanced Cataract Patients

      Efficacy of Swept-source Optical Coherence Tomography in Axial Length Measurement for Advanced Cataract Patients

      SIGNIFICANCE A major limitation of standard time-domain optical coherence tomography–based biometers (TD-OCT) is an inability to measure the axial length (AL) in advanced cataract. A new device that uses swept-source optical coherence tomography (SS-OCT) allows better light penetration. Hence, a considerable number of cataract patients who failed AL measurement by TD-OCT can be recovered by SS-OCT. PURPOSE The purposes of this study were to evaluate the efficacy of an SS-OCT for AL measurement in advanced cataract patients and to identify characteristics of lens opacity that impede the AL measurement. METHODS Advanced cataract patients who were unable to obtain AL ...

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    4. Tear Meniscus Imaging by Anterior Segment-optical Coherence Tomography in Medically Controlled Glaucoma

      Tear Meniscus Imaging by Anterior Segment-optical Coherence Tomography in Medically Controlled Glaucoma

      Purpose: To investigate the tear meniscus (TM) in medically controlled glaucoma patients (MCGP) using Anterior Segment-Optical Coherence Tomography (AS-OCT). Methods: Fifty-six MCGP, twenty-four patients with evaporative dry eye (EDE), and thirty healthy subjects (Controls), were enrolled. MCGP were divided into Group 1 (14 eyes): ß-blockers; Group 2 (14 eyes): prostaglandin analogs; Group 3 (28 eyes) ≥2 drugs. Ocular Surface Disease Index (OSDI) questionnaire, tear film break-up time (TBUT), corneal fluorescein staining (CFS), Schirmer Test I (STI), and tear meniscus height (lower and upper: L-TMH, U-TMH) and area (L-TMA, U-TMA) using AS-OCT, were performed. Results: OSDI score was higher ( P <0 ...

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    5. Peripapillary and Macular Vessel Density Measurement by Optical Coherence Tomography Angiography in Pseudoexfoliation and Primary Open Angle Glaucoma

      Peripapillary and Macular Vessel Density Measurement by Optical Coherence Tomography Angiography in Pseudoexfoliation and Primary Open Angle Glaucoma

      Precis: Pseudoexfoliation glaucoma eyes had a similar level of peripapillary and superficial macular vessel densities compared with primary open-angle glaucoma eyes matched for age and glaucoma severity when assessed by optical coherence tomography angiography. Purpose: To compare vessel density (VD) measured by optical coherence tomography angiography (OCT-A) between primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG) in the peripapillary and macular areas. Methods: The circumpapillary (cpVD), parafoveal (pfVD), and perifoveal vessel densities (perifVD) were obtained using OCT-A (AngioVue/RTVue-XR) in 98 eyes from 98 subjects (age, visual acuity (VA), visual field (VF) mean deviation (MD) matched 49 POAG and 49 ...

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    6. SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study

      SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study

      Purpose: To develop an optical coherence tomography angiography ( OCTA )-based framework for quantitatively analyzing the spatial distribution of choriocapillaris (CC) impairment around choroidal neovascularization ( CNV ) secondary to age-related macular degeneration. Methods: In a retrospective, cross-sectional study, 400-kHz swept-source OCTA images from 7 eyes of 6 patients with CNV secondary to age-related macular degeneration were quantitatively analyzed using custom software. A lesion-centered zonal OCTA analysis technique—which portioned the field-of-view into zones relative to CNV boundaries—was developed to quantify the spatial dependence of CC flow deficits. Results: Quantitative, lesion-centered zonal analysis of CC OCTA images revealed highest flow-deficit percentages near ...

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    7. A Deep Learning Approach in Rebubbling After Descemet's Membrane Endothelial Keratoplasty

      A Deep Learning Approach in Rebubbling After Descemet's Membrane Endothelial Keratoplasty

      Purpose: To evaluate the efficacy of deep learning in judging the need for rebubbling after Descemet's endothelial membrane keratoplasty (DMEK). Methods: This retrospective study included eyes that underwent rebubbling after DMEK ( rebubbling group: RB group) and the same number of eyes that did not require rebubbling (non-RB group), based on medical records. To classify the RB group, randomly selected images from anterior segment optical coherence tomography at postoperative day 5 were evaluated by corneal specialists. The criterion for rebubbling was the condition where graft detachment reached the central 4.0-mm pupil area. We trained nine types of deep neural ...

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    8. Axial length measurement and detection rates using a swept-source optical coherence tomography based biometer in the presence of a dense vitreous hemorrhage

      Axial length measurement and detection rates using a swept-source optical coherence tomography based biometer in the presence of a dense vitreous hemorrhage

      Purpose: To evaluate axial length (AL) measurements and detection rates using a swept-source optical coherence tomography (SS-OCT) biometer (OA-2000, Tomey, Japan) compared with the IOLMaster (v5.4, Carl Zeiss Meditec AG, Germany), Lenstar (v2.1, Haag-Streit, Switzerland) and ultrasound (US) measurements in eyes with vitreous hemorrhage (VH). Setting: Eye Hospital of Wenzhou Medical University, Wenzhou, China. Design: Comparative evaluation of a diagnostic test or technology. Methods: The main outcomes were AL measurement failure rate and agreement in AL measurements in patients with VH. The Bland-Altman method was used to assess the agreement between devices. Results: In total, 40 eyes were ...

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    9. Diagnosing Glaucoma with Spectral-domain Optical Coherence Tomography Using Deep Learning Classifier

      Diagnosing Glaucoma with Spectral-domain Optical Coherence Tomography Using Deep Learning Classifier

      Précis: An SD-OCT based deep learning system detected glaucomatous structural change with high sensitivity and specificity. It outperformed the clinical diagnostic parameters in discriminating glaucomatous eyes from healthy eyes. Purpose: To assess the performance of a deep learning classifier for detection of glaucomatous change based on spectral-domain optical coherence tomography (SD-OCT). Methods: Three hundred and fifty image sets of ganglion cell-inner plexiform layer (GCIPL) and retinal nerve fiber layer (RNFL) SD-OCT for 86 glaucomatous eyes and 307 SD-OCT image sets of 196 healthy participants were recruited and split into training (197 eyes) and test (85 eyes) datasets based on ...

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    10. Optical coherence tomography and fractional flow reserve guided treatment of woven coronary artery anomaly presenting as acute myocardial infarction

      Optical coherence tomography and fractional flow reserve guided treatment of woven coronary artery anomaly presenting as acute myocardial infarction

      Rationale: Woven coronary artery is a very rare congenital anomaly which may lead to acute coronary syndrome in previous literatures. At present, there is no consensus on the treatment of this coronary artery abnormality. Patient concerns: A 48-year-old male was admitted to the other hospital because of persistent chest pain. The electrocardiogram showed an ST-segment elevation in the v1-v5 lead and the patient was diagnosed with acute anterior myocardial infarction. Coronary angiography revealed 2 lumens in the proximal segment of the left anterior descending artery. Then the patient was transferred to our hospital for further diagnosis and treatment. Diagnoses: The ...

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    11. The 360° circumferential opening of Schlemm's canal in normal individuals detected by enhanced depth imaging optical coherence tomography

      The 360° circumferential opening of Schlemm's canal in normal individuals detected by enhanced depth imaging optical coherence tomography

      We aimed to observe the opening status and morphological parameters of Schlemm's canal (SC) in normal eyes using enhanced depth imaging optical coherence tomography (EDI-OCT). Consecutive EDI-OCT scans were used to examine the right eye of 20 normal individuals . EDI-OCT was performed clockwise for 8 regions (at the 12:00, 1:30, 3:00, 4:30, 6:00, 7:30, 9:00 and 10:30 o’clock positions). Image processing and analysis in java software was used to measure the area, perimeter, and diameter of SC. Twenty-one serial scans of each region were evaluated and a total of 168 ...

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    12. Real-Time Intraoperative Dynamics of White Cataract- Intraoperative Optical Coherence Tomography Guided Classification & Management

      Real-Time Intraoperative Dynamics of White Cataract- Intraoperative Optical Coherence Tomography Guided Classification & Management

      Purpose: To evaluate morphological characteristics and intraoperative dynamics of different types of white cataract using intraoperative optical coherence tomography (iOCT) Setting: Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India Design: Prospective interventional study Methods: Fifty eyes with white cataract undergoing phacoemulsification were evaluated. Primary outcome measure was classification of white cataract based on morphology and intraoperative dynamics on iOCT. Secondary outcome measure was rhexis related complications. Results: We identified four types of white cataract based on iOCT - Type I (18%), II (6%), III (48%) and IV (28%). Type I had regularly arranged lamellar ...

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    13. MULTIMODAL IMAGING IN HELLP-RELATED CHORIORETINOPATHY

      MULTIMODAL IMAGING IN HELLP-RELATED CHORIORETINOPATHY

      Purpose: To illustrate with multimodal imaging a case of HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) complicated by bilateral multifocal serous retinal detachments, subretinal exudation, and papilledema. Methods: Case report. Fundus photography, spectral domain optical coherence tomography (SD-OCT), fluorescein angiography , and indocyanine green angiography were performed at presentation and the day after. We also present the SD-OCT follow-up at 8 days, 1 year, and 4 years. Results: A 25-year-old 5-month-pregnant Guinean woman complained about decreased visual acuity in the right eye. Eye fundus and multimodal imaging were abnormal in both eyes. Spectral domain optical coherence tomography showed the presence ...

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    14. Optimization of Implantable Collamer Lens Sizing based on Swept-source Anterior Segment Optical Coherence Tomography

      Optimization of Implantable Collamer Lens Sizing based on Swept-source Anterior Segment Optical Coherence Tomography

      Purpose: To optimize the implantable collamer lens (ICL) sizing method using anterior segment optical coherence tomography (AS-OCT). Setting: Nagoya Eye Clinic, Nagoya, Japan Design: Interventional case series Methods: Stepwise multiple regression analysis was performed using the optimal ICL size as a dependent variable and preoperative AS-OCT parameters as explanatory variables for 81 eyes of 41 patients, and the NK-formula version 2 (NK-formula V2) was obtained. Thereafter, 68 eyes of 42 patients were implanted with the ICL selected as closest to the optimal ICL size calculated by the NK-formula V2. At 3 months postoperatively, the achieved vault was measured by AS-OCT ...

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    15. DIAGNOSIS OF VORTEX VARIX USING OPTICAL COHERENCE TOMOGRAPHY AND SCLERAL INDENTATION

      DIAGNOSIS OF VORTEX VARIX USING OPTICAL COHERENCE TOMOGRAPHY AND SCLERAL INDENTATION

      Purpose: We report a case of a vortex vein varix diagnosed with optical coherence tomography under globe compression. Methods: To illustrate the dynamical behavior of a vortex vein varix , optical coherence tomography was performed with and without gentle globe indentation with a cotton swab. Results: A 51-year-old woman was referred by her optician for an incidental finding of a nonpigmented choroidal mass in the right eye. The patient was asymptomatic with a best-corrected visual acuity of 20/16 in both eyes. On fundoscopy, a prominent smooth pink lesion at the level of the superonasal equatorial retina could be observed in ...

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    16. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY CAN CATEGORIZE DIFFERENT SUBGROUPS OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY CAN CATEGORIZE DIFFERENT SUBGROUPS OF CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION

      Purpose: Choroidal neovascularization ( CNV ) is a common complication of patients affected by age-related macular degeneration , showing a highly variable visual outcome. The main aim of the study was, at baseline, to perform a quantitative optical coherence tomography angiography assessment of CNV secondary to age-related macular degeneration and to assess posttreatment outcomes. Methods: Seventy-eight naïve age-related macular degeneration -related CNV patients (39 men, mean age 78 ± 8 years) were recruited and underwent complete ophthalmologic evaluation and multimodal imaging. Several OCT and optical coherence tomography angiography parameters were collected, including vessel tortuosity and vessel dispersion (VDisp), measured for each segmented CNV ...

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    17. ULTRA-WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY FOR RETINAL DETACHMENT WITH PROLIFERATIVE VITREORETINOPATHY

      ULTRA-WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY FOR RETINAL DETACHMENT WITH PROLIFERATIVE VITREORETINOPATHY

      Purpose: To evaluate the efficacy of using preoperative and postoperative ultra-widefield optical coherence tomography ) images in the treatment of proliferative vitreoretinopathy . Methods: The preoperative and postoperative images of a 62-year-old man with proliferative vitreoretinopathy accompanied by a rhegmatogenous retinal detachment were analyzed. Patient: At the initial examination, the vision was 20/400. It was difficult to obtain clear images of the fundus by color fundus photography because of synechia iridis posterior and mild vitreal opacities. Three-dimensional ultra-widefield optical coherence tomography images showed that the posterior hyaloid membrane was adherent to the retinal surface at a region superior to the macula ...

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    18. Optical Vaginal Biopsy Using Optical Coherence Tomography

      Optical Vaginal Biopsy Using Optical Coherence Tomography

      Objective Optical coherence tomography is a noninvasive technology that visualizes tissue microstructure with high spatial resolution. We designed a novel vaginal system that demonstrates a clear distinction between vaginal tissues planes. In this study, we sought to compare vaginal tomographic images of premenopausal, perimenopausal, and postmenopausal women, demonstrate feasibility of tracking vaginal tissue changes after treatment with fractional-pixel CO 2 laser therapy, and obtain a histologic correlation of these findings. Methods Enrolled subjects underwent imaging and were divided into 3 groups based on menopausal status. Women with genitourinary syndrome of menopause who received fractional-pixel CO 2 laser therapy were assessed ...

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    19. TWO-YEAR FOLLOW-UP OF A RETINAL ASTROCYTIC HAMARTOMA IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      TWO-YEAR FOLLOW-UP OF A RETINAL ASTROCYTIC HAMARTOMA IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To report a case of retinal astrocytic hamartoma imaged by optical coherence tomography angiography (OCTA), followed for 2 years. Methods: Observational case report. Results: A 25-year-old woman was referred for an incidental retinal lesion in the left eye (LE). At baseline, the best-corrected visual acuity in the LE was 20/32, and fundus examination showed the presence of a round, pigmented lesion in juxtafoveal region, corresponding, on spectral domain OCT, to a hyperreflective lesion within nerve fiber layer. Optical coherence tomography angiography revealed the presence of a high-flow lesion in the superficial capillary plexus segmentation. The patient was followed ...

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    20. DIAGNOSTIC CHARACTERISTICS OF POLYPOIDAL CHOROIDAL VASCULOPATHY BASED ON B-SCAN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AND ITS INTERRATER AGREEMENT COMPARED WITH INDOCYANINE GREEN ANGIOGRAPHY

      DIAGNOSTIC CHARACTERISTICS OF POLYPOIDAL CHOROIDAL VASCULOPATHY BASED ON B-SCAN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY AND ITS INTERRATER AGREEMENT COMPARED WITH INDOCYANINE GREEN ANGIOGRAPHY

      Purpose: To examine the characteristics of polypoidal choroidal vasculopathy using B-scan optical coherence tomography angiography (OCTA), and determine the diagnostic criteria of polypoidal choroidal vasculopathy based on OCTA. Methods: This retrospective case series included patients diagnosed with treatment-naïve polypoidal choroidal vasculopathy who underwent indocyanine green angiography (ICGA) and swept-source OCTA at baseline. We compared the characteristics of the polyps detected using B-scan OCTA and ICGA. Then, the diagnostic concordance of each polypoidal lesion between ICGA and OCTA was evaluated. Results: Among 54 eyes of 52 patients, all 54 eyes showed flow signals indicating polyps on both ICGA and B-scan ...

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    21. MASSIVE RETINAL NEOVASCULARIZATION IN VON HIPPEL–LINDAU DISEASE ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR, VITRECTOMY, IMMUNOHISTOCHEMISTRY, AND OPTICAL COHERENCE TOMOGRAPHY FEATURES

      MASSIVE RETINAL NEOVASCULARIZATION IN VON HIPPEL–LINDAU DISEASE ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR, VITRECTOMY, IMMUNOHISTOCHEMISTRY, AND OPTICAL COHERENCE TOMOGRAPHY FEATURES

      Purpose: To report a rare presentation of ocular von Hippel–Lindau disease associated with a massive epiretinal vascular proliferation over the macula removed by vitrectomy and submitted to histological analysis. Methods: Interventional case report. Results: A 13-year-old woman with von Hippel–Lindau disease reported progressive visual loss in the right eye over the preceding 6 months. Best-corrected visual acuity was 20/100 in the right eye. Fundoscopy showed retinal neovascularization (RNV) with macular traction and a small superotemporal hemangioblastoma. Spectral-domain optical coherence tomography confirmed increased macular thickness and macular traction secondary to RNV. Bevacizumab was injected intravitreally, resulting in partial ...

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    22. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF FOCAL CHOROIDAL EXCAVATION AND THE CHOROIDAL STROMA VARIATIONS WITH OCCURRENCE OF EXCAVATION

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF FOCAL CHOROIDAL EXCAVATION AND THE CHOROIDAL STROMA VARIATIONS WITH OCCURRENCE OF EXCAVATION

      Purpose: To describe retinal and choroidal vascular changes and choroidal stroma variations occurring in focal choroidal excavation (FCE). Methods: Study design was a cross-sectional case series. Consecutive patients affected by FCE and healthy controls were recruited. All patients underwent complete ophthalmologic assessment and multimodal imaging, including structural optical coherence tomography and optical coherence tomography angiography. Choroidal thickness and stromal index were calculated from structural optical coherence tomography images. Moreover, we measured vessel density values of superficial capillary plexus, deep capillary plexus, and choriocapillaris at the level of the macula. Results: Twenty-two patients (28 eyes; mean age 57.2 ± 16.4 ...

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    23. Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes

      Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes

      Précis: There is diagnostic information in the outer region of OCTA macula scans not available in the inner region, and this information is especially useful in the early stages of glaucoma . Purpose: To evaluate the diagnostic accuracy of 3×3▒mm 2 and 6×6▒mm 2 macula OCT-A scans for classifying healthy, mild glaucoma , and moderate to severe glaucoma eyes. Methods: Participants enrolled in the Diagnostic Innovations in Glaucoma Study (DIGS) with good quality 3×3▒mm 2 and 6×6▒mm 2 OCT-A images of the macula (AngioVue; Optovue, Freemont, CA) acquired on the same day were ...

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    49-72 of 1640 « 1 2 3 4 5 6 ... 67 68 69 »
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