1. 25-48 of 1644 « 1 2 3 4 5 ... 67 68 69 »
    1. Characteristic findings of acute spontaneous coronary artery dissection by cardiac computed tomography

      Characteristic findings of acute spontaneous coronary artery dissection by cardiac computed tomography

      Background: Spontaneous coronary artery dissection (SCAD) is an infrequent cause of acute coronary syndrome (ACS); however, its detection carries relevant clinical implications. Cardiac computed tomography (CCT) has been found to be useful for follow-up, but data during the acute phase are scarce. Thus, our aim was to evaluate the early diagnostic ability of CCT to detect SCAD. Methods: We retrospectively analyzed all the in-hospital CCT performed in a prospective cohort of patients with SCAD from 2012 to 2016. An independent expert blindly evaluated the studies and described the radiologic characteristics of the lesions. These features were compared with the invasive ...

      Read Full Article
    2. Optic Neuropathy in Charcot–Marie–Tooth Disease

      Optic Neuropathy in Charcot–Marie–Tooth Disease

      Background: Charcot–Marie–Tooth disease Type 2A (CMT2A) presents with optic atrophy in a subset of patients, but the prevalence and severity of optic nerve involvement in relation to other CMT subtypes has not been explored. Methods: Patients with genetically confirmed CMT2A (n = 5), CMT1A (n = 9) and CMTX1 (n = 10) underwent high- and low-contrast acuity testing using Sloan letter charts, and circumpapillary retinal nerve fiber layer (RNFL) and macular total retinal, RNFL, and ganglion cell layer/inner plexiform layer thickness was measured using spectral domain optical coherence tomography (OCT). We used age- and gender-adjusted linear regression to compare contrast ...

      Read Full Article
    3. THE INCIDENCE OF NEOVASCULARIZATION IN CENTRAL SEROUS CHORIORETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      THE INCIDENCE OF NEOVASCULARIZATION IN CENTRAL SEROUS CHORIORETINOPATHY BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To evaluate the incidence of neovascularization (NV) secondary to central serous chorioretinopathy (CSC)—a condition belonging to the spectrum of pachychoroid disorders by means of optical coherence tomography angiography . Methods: One hundred and seventy five eyes with CSC were evaluated in this retrospective observational study. The eyes with acute or chronic CSC with no NV were included in Group 1, and those with NV were evaluated in Group 2. Only eyes that had undergone structural optical coherence tomography and optical coherence tomography angiography were included. Age, best-corrected visual acuity, and subfoveal choroidal thickness were evaluated in all eyes. In ...

      Read Full Article
    4. EPIDEMIOLOGY OF VITREOMACULAR INTERFACE ABNORMALITIES USING MACULAR SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN AN ELDERLY POPULATION (THE MONTRACHET STUDY)

      EPIDEMIOLOGY OF VITREOMACULAR INTERFACE ABNORMALITIES USING MACULAR SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN AN ELDERLY POPULATION (THE MONTRACHET STUDY)

      Purpose: The aim of this study was to investigate the prevalence of vitreomacular interface abnormalities (VMIAs) and to identify associated factors in an elderly population in Europe. Methods: The MONTRACHET (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases) Study is a population-based study, conducted in subjects older than 75 years. Vitreomacular adhesions, vitreomacular tractions, macular holes, epiretinal membranes, and macular cysts were assessed on spectral-domain optical coherence tomography examinations. The prevalence of VMIAs was estimated. We studied the association of demographic and clinical factors with VMIAs. Results: The mean age of the participants was 82.3 (SD, 3.8) years ...

      Read Full Article
    5. QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF INACTIVE MACULAR NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION

      QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF INACTIVE MACULAR NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION

      Purpose: To compare quantitative optical coherence tomography angiography parameters between treatment-naïve quiescent macular neovascularizations (MNVs) and previously treated nonexudative Type 1 MNVs, in patients with age-related macular degeneration . Methods: The eyes included in the study were analyzed by fluorescein angiography, indocyanine green angiography, spectral-domain optical coherence tomography, and optical coherence tomography angiography. According to their medical history and multimodal imaging evaluation, Type 1 MNVs were divided into 2 groups: 1) treatment-naïve quiescent MNVs; 2) previously treated nonexudative Type 1 MNVs. Quantitative optical coherence tomography angiography parameters , including perfusion density (PD), fractal dimension (FD), and lacunarity (LAC) were calculated ...

      Read Full Article
    6. ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY IN A CASE OF ACUTE ZONAL OCCULT OUTER RETINOPATHY

      ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY IN A CASE OF ACUTE ZONAL OCCULT OUTER RETINOPATHY

      Purpose: To report a case of acute zonal occult outer retinopathy in which adaptive optics (AO) facilitated visualization of abnormal photoreceptors previously thought to be in an area of normal retina on conventional optical coherence tomography ( OCT ). Methods: Case report. Results: A 51-year-old woman presents with 11-month history of photopsias and scotoma in the temporal visual field of her left eye. Ocular imaging including fluorescein angiography, fundus autofluorescence and OCT suggested the diagnosis of acute zonal occult outer retinopathy in the left eye. Adaptive optics optical coherence tomography (AO- OCT ) revealed photoreceptor abnormalities not previously identified in conventional OCT , in ...

      Read Full Article
    7. REVISED CLASSIFICATION OF THE OPTICAL COHERENCE TOMOGRAPHY OUTER RETINAL BANDS BASED ON CENTRAL SEROUS CHORIORETINOPATHY ANALYSIS

      REVISED CLASSIFICATION OF THE OPTICAL COHERENCE TOMOGRAPHY OUTER RETINAL BANDS BASED ON CENTRAL SEROUS CHORIORETINOPATHY ANALYSIS

      Purpose: To evaluate the optical coherence tomography ( OCT ) imaging findings in recent onset neurosensory retinal detachments induced by central serous chorioretinopathy and to attempt to corroborate these findings with proposed anatomical correlates. Methods: Retinal detachments due to central serous chorioretinopathy of less than 3 months' duration and the surrounding area were scanned with OCT . The imaging of the outer retinal bands was evaluated according to proposals by Cuenca et al and the IN• OCT Consensus classification. Results: Optical coherence tomography findings in 11 eyes (11 patients) with CSC showed that all hyperreflective bands above Band 4 were variably continuous within ...

      Read Full Article
    8. ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY

      ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY

      Purpose: To determine which spectral domain optical coherence tomography biomarkers of idiopathic macular hole (MH) correlate with the postoperative best-corrected visual acuity (BCVA) in anatomically closed MH. Methods: Retrospective analysis of spectral domain optical coherence tomography scans of 44 patients presenting with MH followed for a mean of 17 months. Widths of MH aperture, base, and ellipsoid zone disruption were calculated from presenting foveal spectral domain optical coherence tomography B-scans. Macular hole base area and ellipsoid zone disruption area were calculated through the custom in-house software. Results: Poorer postoperative BCVA correlated with increased preoperative choroidal hypertransmission (r = 0.503, P ...

      Read Full Article
    9. Anatomical features and clinical outcome of a honeycomb-like structure in the coronary artery: reports from 16 consecutive patients

      Anatomical features and clinical outcome of a honeycomb-like structure in the coronary artery: reports from 16 consecutive patients

      Background: Recanalization of thrombus in coronary artery tree is defined as a honeycomb-like structure . However, the anatomic features and appropriate treatment of honeycomb-like structure still remain largely unclear. Methods and results: Between 2014 July and 2017 December, 17 honeycomb-like structure in 16 patients based on optical coherence tomography and intravascular ultrasound were included. Fractional flow reserve was measured for patients who had thrombolysis in myocardial infarction flow grade 3. Angiographic and optical coherence tomography /intravascular ultrasound-derived variables were studied. Clinical events (until to 2018 December) were collected. Honeycomb-like structures mostly involved left anterior descending artery (68.8%) and localized at ...

      Read Full Article
    10. Use of En Face Optical Coherence Tomography to Monitor Papilledema in Idiopathic Intracranial Hypertension: A Pilot Study

      Use of En Face Optical Coherence Tomography to Monitor Papilledema in Idiopathic Intracranial Hypertension: A Pilot Study

      Background: En face optical coherence tomography (OCT) uses the data acquired during OCT of the optic disc, which typically is used to determine measurements of the peripapillary retinal nerve fiber layer (ppRNFL), to generate a coronal composite fundus image rather than a cross-sectional image. En face OCT has been reported to identify retinal changes related to papilledema in idiopathic intracranial hypertension (IIH) but has not been evaluated for monitoring papilledema. This study aimed to assess the reliability and validity of en face OCT for monitoring papilledema. Methods: Using the Pearson correlation coefficient (R), these measurements were compared with ppRNFL thickness ...

      Read Full Article
    11. Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study

      Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study

      Precis: Angle closure worsens with pharmacological dilatation in about 50.0% of the subjects diagnosed as primary angle closure suspects. Purpose: To evaluate the changes in angle configuration with swept source anterior segment optical coherence tomography before and after pharmacological pupil dilatation in untreated primary angle closure suspects. Patients & Methods: 106 subjects over the age of 50 years and diagnosed as primary angle closure suspects were included in this cross-sectional cohort study.360-degree scans of the angles were captured using swept source optical coherence tomography (SS-1000, Tomey Corporation, Nagoya, Japan) before and 1 hour after pharmacological dilatation . The angle scans ...

      Read Full Article
    12. “Virtual Biopsies” of Normal Skin and Thermal and Chemical Burn Wounds

      “Virtual Biopsies” of Normal Skin and Thermal and Chemical Burn Wounds

      The search for noninvasive methods to image and measure the mechanical properties of skin has been a frequent subject of research for many years. Although suction testing, elastography, and other testing can be noninvasive, these tests fail to yield comparable results to destructive tests such as uniaxial tensile testing. Accordingly, researchers have developed a technique to combine optical coherence tomography with vibrational analysis ( vibrational optical coherence tomography ) to image and analyze the biomechanical properties of tissues noninvasively and nondestructively. The result of this analysis is a “ virtual biopsy ” of skin , along with a physical analysis of the major components of ...

      Read Full Article
    13. Utility of Optical Coherence Tomography (OCT) in Centers For Medicare and Medicaid Services (CMS)-defined Severe Glaucoma Patients

      Utility of Optical Coherence Tomography (OCT) in Centers For Medicare and Medicaid Services (CMS)-defined Severe Glaucoma Patients

      Precis: Patients with Centers For Medicare and Medicaid Services (CMS)-defined severe glaucoma often have clinically useful remaining retinal nerve fiber layer (RNFL), suggesting that structurally based rather than functionally based criteria would be more appropriate to use as guidelines for the utilization of optical coherence tomography (OCT) imaging. Purpose: RNFL OCT in glaucomatous eyes with advanced structural damage can reach a floor after which there is no further detectable thinning of RNFL. Insurers are considering limiting coverage for OCT in “severe stage glaucoma” defined by CMS. However, CMS definitions of severe glaucoma are based primarily on visual field criteria ...

      Read Full Article
    14. Foveal Avascular Zone Measurement Via Optical Coherence Tomography Angiography and its Relationship with the Visual Field in Eyes with Open-angle Glaucoma

      Foveal Avascular Zone Measurement Via Optical Coherence Tomography Angiography and its Relationship with the Visual Field in Eyes with Open-angle Glaucoma

      Précis: The foveal avascular zone in optical coherence tomography angiography is significantly correlated with retinal inner layer thickness, Humphrey field analyzer 10-2 sensitivity threshold, and mean deviation value in open-angle glaucoma patients. Purpose: To measure the foveal avascular zone (FAZ) area using optical coherence tomography angiography (OCTA) and investigate its relationship with retinal inner layer thickness and visual field defects in eyes with open-angle glaucoma (OAG). Participants and Methods: A total of 52 eyes with OAG from 52 patients. FAZ area was measured using OCTA in angio-macula mode. Thicknesses of retinal nerve fiber layer (RNFL), ganglion cell layer plus ...

      Read Full Article
    15. HYPERREFLECTIVE FOVEAL SPOTS IN PATIENTS WITH VITREORETINAL ANOMALIES A Qualitative and Quantitative Analysis

      HYPERREFLECTIVE FOVEAL SPOTS IN PATIENTS WITH VITREORETINAL ANOMALIES A Qualitative and Quantitative Analysis

      Purpose: To describe structural optical coherence tomography (OCT) and OCT angiography features in patients who have developed hyperreflective foveal spots with or without vitreomacular interface abnormalities or with vitreous adhesion alone. Methods: The study design was observational and cross sectional. The presence of defined epiretinal membrane was considered an exclusion criterion. All patients underwent complete ophthalmologic examination, with structural OCT and OCT angiography acquisitions. Both qualitative and quantitative analyses of OCT angiography reconstructions were performed for superficial capillary plexus, deep capillary plexus, and choriocapillaris. Results: Thirty patients (20 men; mean age, 55.2 years) showing hyperreflective foveal spots on structural ...

      Read Full Article
    16. Spectral Domain Optical Coherence Tomography Features

      Spectral Domain Optical Coherence Tomography Features

      Purpose: To investigate the long-term incidence and risk factors of macular hole (MH) development in the fellow eyes of patients with unilateral idiopathic MH. Methods: The retrospective case–control study involved the fellow eyes of 215 consecutive patients with idiopathic MH. The patients were classified into two groups according to the presence or development of MH in the fellow eye. The spectral domain optical coherence tomography features and clinical characteristics of each group were compared. Results: Twelve (5.6%) patients presented with bilateral MH at the initial visit, whereas 20 (9.3%) initially unilateral patients developed MH in the fellow ...

      Read Full Article
    17. OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG

      OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG

      Background/Purpose: Poretti-Boltshauser syndrome is a rare, nonprogressive neurologic syndrome with characteristic cerebellar cysts on neuroimaging due to mutations in LAMA1 . The ophthalmic findings in Poretti-Boltshauser syndrome are not well described. Here, we report the ophthalmic findings from multimodal imaging and electrophysiology of a patient with genetically confirmed Poretti-Boltshauser syndrome . Methods: A 3-year-old boy with confirmed mutations in LAMA1 underwent examination under anesthesia with electroretinography and multimodal imaging including fundus photography, fluorescein angiography , optical coherence tomography , and optical coherence tomography angiography . Results: Dilated fundus examination was notable for retinal vascular anomalies, including a large area of nonperfusion in the temporal ...

      Read Full Article
    18. QUANTITATIVE ASSESSMENT OF THE FOVEAL AVASCULAR ZONE USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY BEFORE AND AFTER SURGERY FOR IDIOPATHIC EPIRETINAL MEMBRANE

      QUANTITATIVE ASSESSMENT OF THE FOVEAL AVASCULAR ZONE USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY BEFORE AND AFTER SURGERY FOR IDIOPATHIC EPIRETINAL MEMBRANE

      Purpose: To investigate, using optical coherence tomography angiography , the foveal avascular zone (FAZar), the FAZ perimeter (FAZp), the acircularity index of the FAZ (FAZai), and the density of vessels surrounding the FAZ (FAZvd) before and after idiopathic epiretinal membrane surgery, and associations of these parameters with postoperative best-corrected visual acuity, letter score gain, and central foveal thickness. Methods: We retrospectively reviewed preoperative and postoperative (sixth month) medical records of 28 eyes of 28 patients who undergone epiretinal membrane surgery and had an intact ellipsoid zone. Results: There were significant increases in best-corrected visual acuity, FAZar, and FAZp and decreases in ...

      Read Full Article
    19. INTRAOPERATIVE OPTICAL COHERENCE TOMOGRAPHY AND ENDOSCOPY-GUIDED EXPLANTATION OF ARGUS II DEVIC

      INTRAOPERATIVE OPTICAL COHERENCE TOMOGRAPHY AND ENDOSCOPY-GUIDED EXPLANTATION OF ARGUS II DEVIC

      Purpose: To describe a surgical approach using intraoperative optical coherence tomography and endoscopy for successful Argus II retinal prosthesis system removal. Methods: Retrospective review of a patient undergoing Argus II explantation 8 months after initial implantation. Results: Successful explantation of the Argus II device was performed in this patient. Conclusion: Explantation of the Argus II device can be a difficult surgery, and intraoperative optical coherence tomography and endoscopy can be used to help avoid potential complications.

      Read Full Article
      Mentions: Duke University
    20. Recent developments in pediatric retina

      Recent developments in pediatric retina

      Purpose of review Pediatric retina is an exciting, but also challenging field, where patient age and cooperation can limit ease of diagnosis of a broad range of congenital and acquired diseases, inherited retinal degenerations are mostly untreatable and surgical outcomes can be quite different from those for adults. This review aims to highlight some recent advances and trends that are improving our ability to care for children with retinal conditions. Recent findings Studies have demonstrated the feasibility of multimodal imaging even in nonsedated infants, with portable optical coherence tomography (OCT) and OCT angiography in particular offering structural insights into diverse ...

      Read Full Article
      Mentions: Duke University
    21. Visual Field Cluster Map Corresponding to Bruch’s Membrane Opening-Minimum Rim Area Sectors in Open-Angle Glaucoma

      Visual Field Cluster Map Corresponding to Bruch’s Membrane Opening-Minimum Rim Area Sectors in Open-Angle Glaucoma

      Précis: We generated a new visual field cluster map corresponding to Bruch’s membrane opening-minimum rim area sectors, which described in detail the structure-function relationships between the optic nerve head and visual field in patients with open-angle glaucoma . Purpose: To investigate the structure-function relationship between Bruch’s membrane opening-minimum rim area (BMO-MRA) and visual field (VF) in patients with open-angle glaucoma . Methods: We retrospectively reviewed 67 eyes of 50 patients with open-angle glaucoma who underwent spectral-domain optical coherence tomography for BMO-MRA and Humphrey VF test. BMO-MRA of the glaucomatous optic nerve head was divided into 12 sectors. The correlation ...

      Read Full Article
    25-48 of 1644 « 1 2 3 4 5 ... 67 68 69 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks