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    1. Interferometric Synthetic Aperture Microscopy: Microscopic Laser Radar

      Interferometric Synthetic Aperture Microscopy: Microscopic Laser Radar
      Combining optical coherence tomography instrumentation and the principles of synthetic aperture radar, researchers have developed a new method for reconstructing 3-D optical images—even in regions that are out of focus in the raw data. Doctors may soon be able to use this approach as a noninvasive diagnostic tool in clinical settings. Microscopic 3-D optical imaging provides guidance to tomorrow’s doctors during surgical interventions. In many clinical scenarios, doctors require high-resolution visualization of tissues and their underlying cellular structures. Perhaps the most common example is for the identification, diagnosis and treatment of cancer. In such cases, clinicians typically take ...
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    2. Optical Biopsy with Confocal Microendoscopy

      Optical Biopsy with Confocal Microendoscopy
      Using optical biopsy methods, doctors can potentially identify cancer and other conditions more accurately, in less time, and earlier in the course of disease than they can with standard screening techniques. Advanced medical imaging procedures such as computed tomography, ultrasound and magnetic resonance imaging have greatly improved physicians’ ability to detect cancer and other diseases. However, in order to make a definitive diagnosis, doctors often need to extract one or more tissue samples from a patient. This process is not only invasive, but can lead to high rates of misdiagnoses, especially when the disease is diffuse or at an early ...
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