1. 1-22 of 22
    1. SD-OCT useful in monitoring glaucoma

      SD-OCT useful in monitoring glaucoma

      Researchers in India have found a way to monitor early and moderate glaucoma using spectral domain optical coherence tomography (SD-OCT): examine the amplitude of the first peak (P1) to the second trough (N2) on a multifocal electroretinogram (mfERG). This, they reported in the British Journal of Ophthalmology , correlates well with retinal nerve fibre layer thickness-full circle (RNFL-FC) and RNFL-superior temporal (RNFL-ST). Between November 2012 and January 2013, the investigators screened patients in whom primary open-angle glaucoma, primary angle-closure glaucoma or normal tension glaucoma had been diagnosed. They evaluated 97 eyes using automated perimetry (Humphrey, Carl Zeiss Meditec), OCT imaging (Cirrus ...

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    2. OCT can characterize corneoscleral junction

      OCT can characterize corneoscleral junction

      Optical coherence tomography (OCT) can be used to characterize the angle and topography of the corneoscleral junction, according to research published in Optometry and Vision Science . The novel, quantitative method used by the researchers also established differences among quadrants of the ocular surface, and between ethnic groups. The researchers recruited a total of 48 subjects (16 Asian, 16 White and 16 Latino), and took OCT images in both eyes of the subjects' nasal, temporal, superior and inferior quadrants. Custom image analysis software allowed selection of a point defining the centre of the corneoscleral junction, and 20 concentric circles were drawn ...

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    3. Swept-source OCT better for imaging posterior sclera, not lamina cribrosa

      Swept-source OCT better for imaging posterior sclera, not lamina cribrosa

      Swept-source optical coherence tomography (OCT) may be superior to enhanced depth imaging (EDI)-OCT in imaging the posterior sclera, but not in imaging the lamina cribrosa, according to a study published on-line in the American Journal of Ophthalmology . Researchers from The Catholic University of Korea, Seoul, obtained both EDI-OCT and swept-source OCT images in 32 myopic patients with glaucoma. B-scan images were used to obtain subfoveal choroidal, subfoveal scleral, and central laminar thicknesses, performed at three locations by two masked observers. With EDI-OCT, the posterior border of the sclera was visible in 31% of eyes, compared with 53% using swept-source ...

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    4. AS-OCT, IVCM find and track epithelial downgrowth after penetrating keratoplasty

      AS-OCT, IVCM find and track epithelial downgrowth after penetrating keratoplasty

      Non-invasive imaging modalities, such as high-resolution anterior-segment optical coherence tomography (AS-OCT) and in-vivo confocal microscopy (IVCM) imaging, may be more sensitive to identifying and monitoring epithelial downgrowth, compared with routine light biomicroscopy in patients undergoing penetrating keratoplasty, and will perhaps replace more invasive diagnostics in these patients, according to a recent case review retrospective study published in the November issue of Cornea. Michael C. Chen, MD, of the University of California, Davis, and fellow researchers, conducted a retrospective case review on two eyes in two patients who had a history of multiple penetrating keratoplasties that developed epithelial downgrowth 4 and ...

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    5. SD-OCT measurements of RNFL thickness may help predict likelihood of glaucoma diagnosis

      SD-OCT measurements of RNFL thickness may help predict likelihood of glaucoma diagnosis

      Researchers have developed a methodology for calculating likelihood ratios for glaucoma diagnosis using continuous retinal nerve fiber layer (RNFL) thickness measurements taken with spectral-domain optical coherence tomography (SD-OCT), and found that average RNFL thickness values < 86 μm were associated with negative likelihood ratios of such a diagnosis. For this observational cohort study, researchers from the Hamilton Glaucoma Center at the University of California, San Diego, recruited a total of 187 patients (262 eyes) with glaucoma and 100 controls (190 eyes) from the Diagnostic Innovations Glaucoma Study. In the glaucoma group, eyes with preperimetric and perimetric glaucomatous damage were included, while ...

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      Mentions: UCSD
    6. Retinal silicone oil emulsification found with SD-OCT

      Retinal silicone oil emulsification found with SD-OCT

      According to recent data small hyperreflective areas found intraretinally, subretinally and underneath the epiretinal membranes with spectral domain optical coherence tomography (SD-OCT) could be small bubbles of emulsified silicone. In this study, the authors (Dr Marie-Hélène Errera et al. , Moorfields Eye Hospital, London, UK, and Centre Hospitalier National des Quinze-Vingts, Paris, France) performed a retrospective case study on 11 eyes of 11 patients. Patients who had undergone vitrectomy and silicone oil tamponade whose SD-OCT imaging had shown silicone oil emulsion manifestations were identified. Out of these 11 patients, 9 had undergone treatment as a result of rhegmatogenous retinal ...

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    7. AF and SD-OCT useful in diagnosis of AIR

      AF and SD-OCT useful in diagnosis of AIR

      Autofluorescence (AF) and spectral domain optical coherence tomography (SD-OCT) can detect structural abnormalities in patients with autoimmune retinopathy (AIR), according to a recent study. Dr Prithvi Mruthyunjaya et al. , Department of Ophthalmology, Duke Eye Centre, Durham, North Carolina, USA, completed a retrospective, observational case series of 14 eyes of seven patients wit AIR. The team collected colour fundus photographs, fundus AF images and SD-OCT at presentation. Six patients had a history of cancer and were diagnosed with cancer-associated retinopathy or melanoma-associated retinopathy. Abnormalities, including loss of outer retinal layers, were found in six patients. One patient presented with cancer-associated retinopathy ...

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    8. Clever combo: multi-modality imaging developed by novel optics

      Clever combo: multi-modality imaging developed by novel optics

      Funding novel optics and imaging software encourages the evolution of multi-modality imaging and provides more business opportunities, according to the latest analysis from Frost and Sullivan. The publication, "Emerging Trends in Optical Imaging Techniques for Drug Discovery, Clinical Diagnostics and Molecular Imaging (Technical Insights)", demonstrates that the development of novel optics, data acquisition methods and image processing software has significantly encouraged the evolution of optical imaging technologies. Optical imaging, at both macroscopic and microscopic levels, are frequently used by clinicians to image tissues with enhanced contrast and resolution capabilities. Prasanna Vadhana Kannan, Senior Research Analyst at Technical Insights, said, "Technology ...

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    9. New imaging modalities give insight into deeper eye structures

      New imaging modalities give insight into deeper eye structures

      New anatomic characteristics of peripapillary intrachoroidal cavitation have been identified using optical coherence tomography (OCT), according to a paper in Retina. Dr Richard Spaide and his team, Manhattan Eye, Ear and Throat Hospital, New York, USA, included 16 eyes of 13 patients in the study. Swept-source OCT was used to image consecutive eyes with peripapillary intrachoroidal cavitation. One eye was subjected to a 1 mm light source whilst the other eye was administered enhanced depth imaging SD-OCT and 3D rendering. The mean spherical refraction of the patients was -12.5 D in the affected eyes. The lesions appeared as yellow-orange ...

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    10. FD-OCT is reliable for epithelial thickness at vertex

      FD-OCT is reliable for epithelial thickness at vertex

      Fourier domain anterior segment optical coherence tomography (FD-OCT) is reliable and reproducible when measuring epithelial thickness at vertex, according to a study in the journal Investigative Ophthalmology and Visual Science. Dr Amar Agarwal and his team, Dr. Agarwal’s Eye Hospital and Eye Research Centre, Chennair, India, conducted a consecutive cross-sectional case series on 210 eyes of 210 patients who underwent anterior segment FD-OCT. Corneal thickness was measured by a calliper software tool. Two professionals completed the examinations within 30 minutes of each other. The outcome measures included total corneal thickness, epithelial thickness, and corneal thickness excluding the epithelium. Mean ...

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      Mentions: Amar Agarwal
    11. Advantages of OCT for both patient and doctor

      Advantages of OCT for both patient and doctor

      "One of the major advantages of spectral-domain optical coherence tomography (SD-OCT) is the ability to create three dimensional (3D) samples of the tissue showing us much more detail so we can get a much better insight and understanding," according to Professor Albert Augustin (Department of Ophthalmology, Klinikum Karlsruhe, Germany) during the Carl Zeiss Meditec evening symposium at the 2011 annual ESCRS congress.

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    12. OCT for glaucoma: Today and tomorrow

      OCT for glaucoma: Today and tomorrow

      Spectral-domain optical coherence tomography (SD-OCT) is now an established diagnostic tool for optic nerve diseases such as glaucoma. Since the first studies on glaucomatous eyes were published a decade ago using time-domain OCT (TD-OCT), remarkable advances have been realized. Today ophthalmologists can use SD-OCT to investigate several parameters in cases with any degree of glaucoma. These are derived from the peripapillary retinal nerve fibre layer (RNFL), the optic nerve head (ONH) and the macular ganglion cells (GC). Comprehensive analysis of these data help the clinician in making the diagnosis and following patients up

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    13. AS-OCT produces better results after long-term dark adaptation

      AS-OCT produces better results after long-term dark adaptation
      A paper published in the Journal of Glaucoma has announced the increased reliability of anterior-segment optical coherence tomography (AS-OCT) when used on patients after long-term dark adaptation. Dr Dejiao Li et al., Optoelectronics Research Centre, University of Southampton, Hampshire, UK, split 110 participants into 2 groups a study group and a control group. In the study group there were 70 suspects of primary angle closure and in the control group there were 40 normal participants. AS-OCT was used to measure the anterior chamber angle configuration and pupil diameter at both 3 minutes and 1.5 hours of dark adaptation. The ...
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    14. Frontiers and Controversies in Structural and Functional Ocular Imaging

      Frontiers and Controversies in Structural and Functional Ocular Imaging

      Heidelberg Engineering has designed, manufactured and distributed diagnostic instruments for eye care professionals for 20 years. In celebration of this milestone the company held a two-day symposium in Heidelberg, Germany, demonstrating the integral part the company has played and continues to play in worldwide research and clinical practice. “Frontiers and controversies in structural and functional ocular imaging” featured a plethora of experts from all over the world discussing their research and results in imaging and diagnostics. In this supplement Ophthalmology Times Europe and Heidelberg Engineering present the highlights of the 20th Anniversary symposium.

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    15. SD-OCT provides better quality images of chorodial osteoma

      SD-OCT provides better quality images of chorodial osteoma

      Spectral domain-optical coherence tomography (SD-OCT) provides higher resolution images of chorodial osteoma compared with time domain-OCT, reveals a study published in the British Journal of Ophthalmology.Dr Paul T. Finger et al., The New York Eye Cancer Center, New York, USA, studied 11 chorodial osteoma patients in a retrospective chart review. The review included patient, clinical, ultrasonographic, photographic and SD-OCT imaging.The results demonstrated that the mean basal diameters of tumours recorded by fundus photography and ultrasound imaging were 5.2 mm and 6.4 mm respectively. In two cases, tumours were SD-OCT hyporeflective, hyperreflective in two cases and SD-OCT ...

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      Mentions: Paul T. Finger
    16. Optical coherence tomography (Article by Dr. Sebastian Wolf)

      Optical coherence tomography (Article by Dr. Sebastian Wolf)
      The introduction of optical coherence tomography (OCT) in 1991 by Huang and associates,1 has become a tremendous turning point in the development of the ophthalmic imaging field. Clinical application of OCT in ophthalmology has undergone rapid evolution especially with the introduction spectral domain OCT (SD-OCT).
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    17. Fourier-domain OCT gives consistent results for flap-thickness measurements

      Fourier-domain OCT gives consistent results for flap-thickness measurements
      A recent study published in the Journal of Cataract and Refractive Surgery has established that Fourier-domain optical coherence tomography (OCT) gives the highly repeatable flap-thickness measurements. A team led by Dr Yan Li, Doheny Eye Institute, University of Southern California, Los Angeles, California, USA, conducted a case series evaluation of the repeatability of Fourier-domain OCT on 21 patients. One week after LASIK, Fourier-domain OCT was used to measure flap thickness at 6 positions over the corneal flap. Pooled standard deviations (SDs) were used to calculate within-grade flap thickness repeatability and between-grader reproducibility. The results demonstrated that the mean flap thickness ...
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    18. Cataracts affect RNFL and OCT output

      Cataracts affect RNFL and OCT output
      The presence of cataracts could influence optical coherence tomography (OCT) signal strength (SS) and peripapillary retinal nerve fibre layer (RNFL) thickness measurements, according to a study published in the Journal of Glaucoma. Dr Jean Mwanza et al., Basom Palmer Eye Institute, University of Miami, Leonard Miller School of Medicine, Miami, Florida, USA, studied 45 cataract patients, 23 of which had glaucoma. Cataracts were graded with the Lens Opacities Classification System III. Stratus OCT scans were used to measure peripapillary RNFL before and after cataract surgery. The results revealed a significant postoperative difference in RNFL thickness in patients with a lower ...
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    19. Scatter Matters

      Advances in intraocular lens (IOL) design have improved the visual outcomes of cataract surgery considerably. Multifocal IOLs attempt to provide the patient with distance and near vision by increasingthe depth-of-field, showing improved optical quality and near vision which further improves with time. They take advantage of the brain’s natural ability to adapt to near and far vision, as the different opticalelements of the lens can be used as required, depending on the distance of fixation. This means that, when viewing a distant object, a sharp retinal image is provided by those parts of the lens within the pupillary area ...

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    20. Investigating late onset decentration in iris-fixated pIOLs

      Investigating late onset decentration in iris-fixated pIOLs
      An investigation into late-onset shifting of the haptics through the iris tissue. Previous studies have demonstrated that irisfixated phakic intraocular lenses (pIOLs) show stable and predictable visual results, when strict inclusion criteria for implantation are applied.1-3 It is important that these pIOLs stay in position after implantation, to prevent damage to intraocular tissues and retain a good quality of vision. Anterior segment optical coherence tomography (AS-OCT) is a new imaging device, which allows a rapid, noncontact examination, and the software includes a measuring system capable of calculating distances between two points.
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    21. Distinct DME patterns seen on OCT

      Optical coherence tomography (OCT) is valuable in managing diabetic macular oedema (DME), more so than fluorescein angiography, in which the degree of leakage is not correlated with visual acuity and outcomes, according to Peter Kaiser, MD. In addition, angiography does not show vitreoretinal abnormalities that may require a different treatment. OCT provides a retinal thickness map that correlates well with leakage clinically, fluorescein leakage, and more importantly, with decreased visual acuity. The maps can be used to track progression and treatment efficacy, according to Dr Kaiser, of the Cole Eye Institute, Cleveland Clinic, Ohio, US. The OCT single scan tomograms ...
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    1-22 of 22
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