1. 1-11 of 11
    1. Imaging of the Cornea: Topography vs Tomography

      Imaging of the Cornea: Topography vs Tomography
      At times technical advancements are significant enough to warrant a change or revision in terminology. For example, the classification and proper terminology of laser corneal surgery have been previously addressed so that surgeons and investigators around the world would “make sense in keratospeaking.” This is also the case when newer diagnostic instrumentation offers either more or different information than was previously available. It is our belief that we have reached that point with newer methods of imaging the cornea and anterior segment, thereby, revisiting the “keratospeak” regarding the terminology for corneal characterization.
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    2. Efficacy of Corneal Collagen Cross-linking Using a Custom Epithelial Debridement Technique in Thin Corneas: A Confocal Microscopy Study

      Efficacy of Corneal Collagen Cross-linking Using a Custom Epithelial Debridement Technique in Thin Corneas: A Confocal Microscopy Study
      Confocal microscopy, slit-lamp examination, and optical coherence tomography (OCT) after corneal cross-linking (CXL) combined with partial epithelium removal showed that CXL occurred in areas of epithelial debridement only whereas the thin parts of the cornea covered with epithelium did not show the effect of CXL.
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    3. Anterior Segment Optical Coherence Tomography Measurement of LASIK Flaps: Femtosecond Laser vs Microkeratome

      Anterior Segment Optical Coherence Tomography Measurement of LASIK Flaps: Femtosecond Laser vs Microkeratome

      In a series of 72 patients, a LASIK flap was made in one eye with the AMO IntraLase FS60 and in the other eye with the Moria M2 microkeratome and postoperative thickness patterns were measured with the Visante OCT in 20 locations in each eye. In the femtosecond laser group, the average deviation of flap thickness from intended was 5.54 µm, in the microkeratome eyes it was 10.28 µm, with a greater standard deviation for the Moria M2 and more uniformity of thickness across the flap for the IntraLase FS60.

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    4. Control of Femtosecond Thin-flap LASIK Using OCT in Human Donor Eyes

      PURPOSE Thin-flap keratomileusis is a procedure that minimizes LASIK flap thickness to preserve both the corneal epithelium and the maximum residual stroma. This study investigated the usefulness of optical coherence tomography (OCT) as a tool in guiding the femtosecond laser in the creation of a thin flap in human eyes in a non-randomized case series. METHODS In a private research laboratory, an in vitro investigation was performed on human autopsy eyes. Five human cadaver eyes, unsuitable for transplantation, underwent flap creation with a femtosecond laser. The laser procedure was controlled in real-time with an OCT system (Thorlabs HL AG) to ...
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    5. Central Corneal Thickness, Anterior Chamber Depth, and Pupil Diameter Measurements Using Visante OCT, Orbscan, and Pentacam

      PURPOSE To evaluate the agreement among three different optical methods in measuring anterior chamber depth (ACD), central corneal thickness (CCT), and pupil diameter. METHODS One hundred eyes of 50 healthy patients (25 men, 25 women) were enrolled in the study. Mean patient age was 25 years (range: 21 to 32 years). Exclusion criteria were history of any intraocular or corneal surgery, contact lens wear, corneal anomalies, and spherical refraction >5.00 diopters (D) or cylindrical refraction >2.00 D. All measurements were done by the same operator under mesopic light conditions and repeated using three different optical methods: Visante optical ...
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    6. Comparison of Internal Anterior Chamber Diameter Imaging Modalities: 35-MHz Ultrasound Biomicroscopy, Visante Optical Coherence Tomography, and Pentacam

      PURPOSE To compare the internal diameter of the anterior chamber among three different imaging modalities: 35-MHz ultrasound biomicroscopy (UBM), Visante optical coherence tomography (OCT), and Pentacam, and to compare the internal diameters with white-to-white (WTW) distance measured by Orbscan. METHODS The internal horizontal anterior chamber diameter was measured in 20 normal eyes using 35-MHz UBM (Optikon), Visante OCT (Carl Zeiss Meditec), and Pentacam (Oculus Inc). The mean horizontal anterior chamber diameters were compared, and the correlations between each pair of two different methods were evaluated. Horizontal WTW distance was measured by Orbscan IIz (Bausch & Lomb-Orbtek Inc) and then correlated with ...
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    7. Ciliary Sulcus Diameter and Two Anterior Chamber Parameters Measured by Optical Coherence Tomography and VHF Ultrasound

      PURPOSE To evaluate the relationship between two anterior chamber anatomical parameters, angle-to-angle and iris pigment end-to-iris pigment end distances, and sulcus-to-sulcus diameter. METHODS Twenty eyes without active ocular pathologies or previous ocular surgeries from 20 patients ranging in age from 23 to 51 years were included in this study. Mean spherical equivalent refraction ranged from +5.50 to –7.00 diopters. Angle-to-angle and iris pigment end-to-iris pigment end distances were measured in all cases three times consecutively using two technologies: optical coherence tomography (OCT) and very high-frequency ultrasonography. Sulcus-to-sulcus diameter was additionally obtained by ultrasonography. Correlation, linear regression, intrasession, and ...
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      Mentions: Jorge L. Alio
    8. Effect of a Suction Device for Femtosecond Laser on Anterior Chamber Depth and Crystalline Lens Position Measured by OCT

      PURPOSE To investigate the position and stability of the crystalline lens after application of a suction device containing a contact lens and a vacuum unit for the treatment of presbyopia using a femtosecond laser. METHODS Twenty presbyopic (44.4±4.3 years) and 5 pre-presbyopic patients (31.6±3.8 years) were included. The anterior chamber depth, along with the position of the lens, was investigated before and after application of the suction device with optical coherence tomography (Visante OCT; Carl Zeiss Meditec AG). The type of suction device is routinely used for femtosecond LASIK with the VisuMax laser (Carl ...
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    9. In Vivo Application and Imaging of Intralenticular Femtosecond Laser Pulses for the Restoration of Accommodation

      PURPOSE According to the Helmholtz theory of accommodation, one major cause of the development of presbyopia is the increasing sclerosis of the crystalline lens. One concept for regaining the elasticity of the sclerosing lens is intralenticular treatment by femtosecond laser pulses. METHODS The feasibility of applying and imaging in vivo microincisions by femtosecond laser pulses was evaluated in five rabbit lenses with a new high repetition rate (100 kHz) femtosecond laser unit. The treated eyes were monitored using optical coherence tomography (OCT) and Scheimpflug imaging for localizing and studying the tissue effects of the incisions. The rabbits were investigated preoperatively ...
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    10. Measurement of LASIK Flap Thickness With Anterior Segment Optical Coherence Tomography

      PURPOSE To assess the interobserver variability and agreement of anterior segment optical coherence tomography (OCT) in the measurement of LASIK flap thickness, and to compare the results with intraoperative ultrasound pachymetry measurements. METHODS Thirty-nine eyes of 20 consecutive patients undergoing LASIK with the XP microkeratome (Bausch & Lomb) and ALLEGRETTO Eye-Q laser system (WaveLight Inc) had corneal flap thickness measured with SP-100 ultrasound (Tomey Corp) intraoperatively and with OCT (Visante; Carl Zeiss Meditec Inc) postoperatively. Interobserver assessment was performed by comparing the flap thickness measurements obtained from the same scan by 2 masked, independent observers. Agreement of OCT scan was determined by assessment of 2 different scans of the same eye by the same observer. RESULTS Mean (±standard deviation) flap thickness measured by ultrasound ...
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    11. A Test Eye for Wavefront Eye Refractors

      A Test Eye for Wavefront Eye Refractors
      PURPOSE A multi-site study was conducted to test feasibility of a modified automatic refractor style test eye as a test device for wavefront refractors of various types and to determine whether a) they could be measured and b) when measurements could be made, to see if they were similar. This study did not attempt to assess which instrument most accurately measures the aberrations of the test eye or human eye. METHODS Three automatic refractor style test eyes were modified for use as test devices for wavefront refractors. One had a simple spherical front surface, and two had additional aberrations added ...
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