1. Articles from Resolve a DOI

    dx.doi.org

  2. 1-14 of 14
    1. Optical Coherence Tomography Transecting an Omega Retinal Venous Loop en Face in a Patient With Diabetic Retinopathy

      Optical Coherence Tomography Transecting an Omega Retinal Venous Loop en Face in a Patient With Diabetic Retinopathy

      The image depicts a woman in her mid-40s with poorly controlled insulin-dependent diabetes and bilateral proliferative diabetic retinopathy. Fundus photography of the left eye with corresponding spectral-domain optical coherence tomography captured an omega retinal venous loop en face ( Figure , A). This image demonstrates that the venous loop is located in the preretinal plane and is in direct contact with the posterior hyaloid face ( Figure , B).

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    2. The Quantitative Measurements of Vascular Density and Flow Area of Optic Nerve Head Using Optical Coherence Tomography Angiography

      The Quantitative Measurements of Vascular Density and Flow Area of Optic Nerve Head Using Optical Coherence Tomography Angiography

      Purpose: The purpose of this study was to evaluate the vascular density (VD) and the flow area on optic nerve head (ONH) and peripapillary area, and the impact of age and sex using optical coherence tomography angiography (OCTA) in healthy human subjects. Methods: Both eyes of each volunteer were scanned by an RTVue XR Avanti; Optovue with OCTA using the split-spectrum amplitude-decorrelation angiography algorithm technique. Masked graders evaluated enface angiodisc OCTA data. The flow area of ONH and the VD were automatically calculated. Results: A total of 79 eyes of patients with a mean age of 37.03+/-11.27 ...

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    3. Resolution characteristics of optical coherence tomography for dental use

      Resolution characteristics of optical coherence tomography for dental use

      OBJECTIVES: The purpose of this study was to clarify resolution characteristics of optical coherence tomography (OCT) for dental use. METHODS: Two types of swept-source OCT machines (SS-OCTs) were employed in this study. To clarify their resolution characteristics, we newly developed a glass chart device with a ladder pattern of wavelengths, which ranged from (4 x 2) µm to (1024 x 2) µm, as well as a star-target pattern, a grid pattern, and a spatial frequency response pattern. The resolving powers and characteristics of the OCTs were subjectively evaluated. RESULTS: The Santec OCT had a resolving power of 64 µm in ...

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    4. Extinction measurement of dense media by an optical coherence tomography technique

      Extinction measurement of dense media by an optical coherence tomography technique

      he optical coherence tomography will make progress as the next stage toward a spectroscopic analysis technique. The spectroscopic analysis is based on the Beer-Lambert law. The absorption and scattering coefficients even for the dense medium can be measured by the Beer-Lambert law because the OCT can detect only the light keeping the coherency which propagated rectilinearly and retro-reflected from scatters. This study is concerned with the quantitative verification of Beer-Lambert law in the OCT imaging.

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      Mentions: Toshiaki Iwai
    5. Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Purpose To compare signal penetration depth and deep structure-visualization of swept source (SS) and spectral domain (SD)-optical coherence tomography (OCT) with and without enhanced depth imaging (EDI) and B-scan averaging modes. Methods Volume scans were obtained from 20 eyes of healthy volunteers by DRI OCT-1, Spectralis using EDI and B-scan averaging, and Cirrus HD-OCT. The signal penetration depth was measured as the distance between the retinal pigment epithelium and the deepest visible anatomical structure at the foveal center. Visibility and contrast of the choroidoscleral junction and of vascular details within the choroid were assessed across the entire volume using ...

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    6. Analysis of optimum conditions of depolarization imaging by polarization-sensitive optical coherence tomography in the human retina

      Analysis of optimum conditions of depolarization imaging by polarization-sensitive optical coherence tomography in the human retina

      Measurement and imaging of depolarization by polarization-sensitive optical coherence tomography (PS-OCT) requires averaging of Stokes vector elements within two- or three-dimensional (3-D) evaluation windows to obtain the degree of polarization uniformity (DOPU). By use of a PS-OCT system with an integrated retinal tracker, we analyze optimum conditions for depolarization imaging, data processing, and segmentation of depolarizing tissue in the human retina. The trade-offs between figures of merit like DOPU imaging sensitivity, efficiency, and susceptibility are evaluated in terms of 3-D resolution. The results are used for a new, detailed interpretation of PS-OCT high-resolution images of the human retinal pigment epithelium ...

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    7. Detection of retinal nerve fibre layer degeneration in patients with Alzheimer's disease using optical coherence tomography: searching new biomarkers

      Detection of retinal nerve fibre layer degeneration in patients with Alzheimer's disease using optical coherence tomography: searching new biomarkers

      PURPOSE: To explore the features of filtering blebs exhibiting transconjunctival oozing via three-dimensional anterior segment optical coherence tomography (3D AS-OCT). METHODS: In this cross-sectional study, 131 eyes of 131 patients exhibiting filtering blebs were examined. Of those, 20 eyes were excluded as flat-shaped, non-functioning bleb. Transconjunctival oozing was defined as transconjunctival aqueous egress evident on the bleb surface, in the absence of any point leak observable using a slit-lamp, as confirmed by application of digital pressure. Total bleb height, the height of the fluid-filled cavity, and bleb wall thickness and density were measured using 3D AS-OCT. Patient age, the etiology ...

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    8. Monitoring of Cerebral Hemodynamics Post Optogenetic Stimulation via Optical Coherence Tomography

      Monitoring of Cerebral Hemodynamics Post Optogenetic Stimulation via Optical Coherence Tomography

      In this article Spectral Domain Optical Coherence Tomography is used to measure the hemodynamic response induced by optogenetic stimulation in the somatosensory cortex of transgenic mice. By analyzing the 3D angiograms and Doppler measurements produced by coherence tomography, we observed significant increase in blood flow as a result of increased vessel diameter and blood velocity following optical stimulation of cortical neurons. Such distinct responses were not observed in control experiments where the brain of wildtype mice were exposed to the same light pulses.

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    9. Macular Hole Formation Secondary to Bacterial Septic Embolism Demonstrated by Serial Spectral-domain Optical Coherence Tomography Imaging

      Macular Hole Formation Secondary to Bacterial Septic Embolism Demonstrated by Serial Spectral-domain Optical Coherence Tomography Imaging

      Purpose : To describe a case of macular hole (MH) formation secondary to bacterial septic embolism and demonstrate the changing thereof using serial spectral-domain optical coherence tomography (SD-OCT) images. Methods : A single case report. Results : A 69-year-old woman who had been diagnosed with Klebsiella pneumonia septicemia was referred for decreased vision in her left eye. Impending MH was detected by SD-OCT and retinitis with multiple retinal hemorrhages by funduscopy. One week after the initial visit, a full-thickness MH had formed, and 13 weeks after the initial visit, we were able to close the MH following vitrectomy and gas tamponade. The MH ...

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    10. Prevalence of optical coherence tomography-diagnosed postoperative cystoid macular oedema in patients following uncomplicated phaco-emulsification cataract surgery

      Prevalence of optical coherence tomography-diagnosed postoperative cystoid macular oedema in patients following uncomplicated phaco-emulsification cataract surgery

      Background:  Postoperative cystoid macular oedema is a complication of uneventful cataract surgery. Whereas improved surgical techniques have decreased the incidence of cystoid macular oedema, it remains a cause of unfavourable visual outcome following surgery. Fundus fluorescein angiography has been the ‘gold standard’ for diagnosing subclinical cystoid macular oedema; however, non-invasive cross-sectional imaging of the retina with optical coherence tomography may be equally effective at detecting the condition and offers the ability to quantify and repeat results over time.Design:  Prospective pre–post case series of patients undergoing routine phaco-emulsification surgery.Participants:  Eighty consecutive patients (100 eyes) with cataracts and an ...

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    11. Optical coherence tomography of the retina and optic nerve – a review

      Optical coherence tomography (OCT) is a rapid non-contact method that allows in vivo imaging of the retina, optic nerve head and retinal nerve fibre layer (RNFL). Since its introduction in Ophthalmology approximately a decade ago, the use of this technology has disseminated into the clinical practice. OCT has proven to be a useful ancillary tool for assessing retinal diseases because of its capability to provide cross-sectional images of the retina, and also to perform quantitative analysis of retinal morphology. In glaucoma, the OCT represents one of the methods capable of documenting and analysing optic disc and RNFL morphology in attempt ...
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    12. Clinical use and research applications of Heidelberg retinal angiography and spectral-domain optical coherence tomography - a review

      Fluorescein angiography (FA) was discovered by Nowotny and Alvis in the 1960s of the 20th century and has evolved to become the 'Gold standard' for macular diagnostics. Scanning laser imaging technology achieved enhancement of contrast and resolution. The combined Heidelberg retina angiograph (HRA2) adds novel innovative features to established fundus cameras. The principle of confocal scanning laser imaging provides a high resolution of retinal and choroidal vasculature with low light exposure providing comfort and safety for the patient. Enhanced contrast, details and image sharpness image are generated using confocality. For the visualization of the choroid an indocyanine green angiography (ICGA ...
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    13. Imaging the vitreous: optical coherence tomography and ultrasound imaging

      Imaging the vitreous in optically transparent and translucent ocular media using OCT and in optically opaque ocular media using ultrasound is discussed. Optical coherence tomography and colour flow mapping are briefly described. Images of tomograms, B-mode sections, and colour flow maps illustrate the use of these techniques in imaging the vitreous.
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    14. Optical coherence tomography permits detailed characterization of vulnerable plaques

      Intravascular optical coherence tomography (OCT) is an optical analog of intravascular ultrasonography (IVUS)—the current standard invasive method for diagnosing coronary artery disease. OCT has a markedly higher resolution than IVUS, and can resolve microstructures of atherosclerotic plaques that are thought to be associated with plaque vulnerability, such as thin fibrous caps, lipid cores and intracoronary thrombi. To determine whether OCT is superior to IVUS and coronary angioscopy for the evaluation of atherosclerotic plaques, Kubo et al. enrolled 30 patients with acute myocardial infarction and used each modality to analyze the culprit lesions.
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    1-14 of 14
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