Margin Assessment in Renal Surgery Using a Handheld Optical Coherence Tomography Probe
Objective To assess the use of a handheld optical coherence tomography (OCT) probe for the evaluation of intraoperative surgical margins during partial nephrectomy (PN). Methods In an initial feasibility study, a radical nephrectomy specimen with a 9-cm tumor was cut into 19 sections, exposing 0 mm (n=8), 1 mm (n=6), and 2 mm (n=5) gross margins. OCT was used to determine the margin width in each specimen. Second, a prospective ex vivo assessment of 15 PN tumor specimens was performed with OCT to determine margin status and to measure the attenuation coefficient (AC) of tumor and renal ...
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