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    1. Cataract quantification using swept-source optical coherence tomography

      Cataract quantification using swept-source optical coherence tomography

      The stated purpose of the study by Brás et al. 1 was to develop and evaluate a cataract quantification method using a swept-source optical coherence tomography (SS-OCT) device (IOLMaster 700, Carl Zeiss Meditec AG). We were disappointed that the authors failed to cite our article published in your journal in December 2017, 2 well before the submission of their paper at the end of March 2018. Our abstract explicitly states the purpose of our study: “To assess a new objective cataract grading method based on lens densitometry on swept-source optical coherence tomography…scans provided by the IOLMaster 700.” We ...

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    2. Using preoperative anterior segment optical coherence tomography to highly predict posterior capsule dehiscence in posterior polar cataract with simple image adjustments

      Using preoperative anterior segment optical coherence tomography to highly predict posterior capsule dehiscence in posterior polar cataract with simple image adjustments

      In the study by Pavan Kumar et al., 1 the authors addressed an important issue for clinical practice and reported that anterior segment optical coherence tomography (AS-OCT) has high sensitivity (100%) and specificity (94.9%) for predicting posterior capsule rupture during phacoemulsification surgery in eyes with posterior polar cataract.

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    3. Intralenticular changes on optical coherence tomography in eyes with mature brown cataract

      Intralenticular changes on optical coherence tomography in eyes with mature brown cataract

      We modified the posterior segment optical coherence tomography (OCT) process to image anterior segment structures by keeping a 20.0 diopter lens along its aperture (Figure 1, A ). We were measuring the central corneal thickness using this technique and we noticed some empty pockets within the anterior lens matter. We discuss these findings in 2 cases.

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    4. A comparative analysis of two swept-source optical coherence tomography biometers

      A comparative analysis of two swept-source optical coherence tomography biometers

      Purpose To report the level of agreement, repeatability and correlation of two swept-source optical coherence tomography (SS-OCT) biometers, the IOLMaster 700 (Carl Zeiss Meditec AG, Germany) (reference biometer) and the Argos (Movu, Inc.) (new biometer), in terms of axial length (AL), keratometric mean (mean K), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and corneal diameter (CD). Setting Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. Design Retrospective, comparative case-series. Methods Each participant underwent SS-OCT biometry with the reference and new biometer. In addition to reporting the statistical results derived from both eyes, this study included ...

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    5. Triphasic polymeric corneal coating gel versus balanced salt solution irrigation during cataract surgery: a postoperative anterior segment optical coherence tomography analysis and confocal microscopy evaluation

      Triphasic polymeric corneal coating gel versus balanced salt solution irrigation during cataract surgery: a postoperative anterior segment optical coherence tomography analysis and confocal microscopy evaluation

      Purpose To investigate the safety and efficacy of the intra-operative use of a triphasic polymeric gel as corneal coating during cataract surgery and its effect on postoperative ocular comfort Setting Eye Clinic, University of Florence, Italy Design Longitudinal observational retrospective study Methods Data of 25 patients who received an application of polysaccharide blend on corneal surface (EyeDro – Alchimia s.r.l., hydroxypropyl methylcellulose, xanthan gum and carrageenan) and of 27 eyes who received balanced salt solution (BSS) during phacoemulsification surgery were analyzed. Central Corneal Thickness (CCT) and Epithelial Thickness (ET) were examined using Anterior Segment Optical Coherence Tomography (AS-OCT) and ...

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    6. Comparison of anterior segment measurements obtained using a swept-source optical coherence tomography biometer and a Scheimpflug–Placido tomographer

      Comparison of anterior segment measurements obtained using a swept-source optical coherence tomography biometer and a Scheimpflug–Placido tomographer

      Purpose To assess the repeatability and agreement of anterior segment measurements between an optical biometer (IOLMaster 700) using swept-source optical coherence tomography and a Scheimpflug–Placido tomographer (Sirius) in patients scheduled for corneal refractive surgery. Setting Eye Hospital of Wenzhou Medical University, Zhejiang, China. Design Prospective case series. Methods The parameters, including the central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, keratometry (K) values, astigmatism, J0 (Jackson cross-cylinder with axes at 180 degree and 90 degrees) and J45 vectors (Jackson cross-cylinder with axes at 45 degrees and 135 degrees), and horizontal corneal diameter, were measured 3 times per ...

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    7. Predictability of the vault after posterior chamber phakic intraocular lens implantation using anterior segment optical coherence tomography

      Predictability of the vault after posterior chamber phakic intraocular lens implantation using anterior segment optical coherence tomography

      Purpose The aim of this retrospective study was to determine if the vault measurement, after hole implantable collamer lens (hole ICL, KS-AquaPORT) surgery, can be predicted by angle-to-angle (ATA) and white-to-white (WTW) measurements on anterior segment (AS) optical coherence tomography (OCT). Setting Sanno Hospital, Tokyo, Japan. Design Retrospective case series. Methods The study included 44 eyes (23 patients) that were observed for 3 months following hole ICL implantation for myopia or myopic astigmatism. The mean patient age and preoperative spherical equivalent, ATA, and WTW values were 36.2±8.8 years, -6.23±3.41 D, 12.03±0.40 ...

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    8. Prevalence Of Macular Abnormalities Identified Only By Optical Coherence Tomography In Brazilian Patients With Cataract

      Prevalence Of Macular Abnormalities Identified Only By Optical Coherence Tomography In Brazilian Patients With Cataract

      Purpose To assess the prevalence of macular abnormalities not suspected by the biomicroscopic fundus exam and identified only by macular optical coherence tomography (OCT) in the preoperative evaluation for cataract surgery in a large series of Brazilian patients. Setting Private practice, Recife, Brazil. Design Retrospective case series. Methods All eyes that underwent cataract surgery by a single physician between August 2014 and July 2016 were eligible. We excluded eyes with a previous diagnosis of macular abnormalities, with a suspicious biomicroscopic fundus exam, and those without OCT results. Based on the preoperative macular OCT, patients were subdivided in two groups: those ...

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    9. Role of anterior segment optical coherence tomography for safer management of mature white cataracts

      Role of anterior segment optical coherence tomography for safer management of mature white cataracts

      Purpose Role of anterior segment optical coherence tomography for safer management of mature white cataracts Setting Patients with mature white cataract attending the outpatient department of a tertiary eye care hospital, aspiring to get cataract surgery done, were scheduled for elective phacoemulsification and intraocular lens implantation by two surgeons during the time period of October 2017 till March 2018. Design A prospective interventional study of 30 patients. Methods All patients with mature cataracts and absence of any retinal pathology, underwent anterior segment optical coherence tomography (ASOCT) to assess the presence or absence of intra-lenticular subcapsular fluid pockets. The patients with ...

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    10. Cataract quantification using swept-source optical coherence tomography

      Cataract quantification using swept-source optical coherence tomography

      Purpose To develop and evaluate a cataract quantification method using a swept-source optical coherence tomography (SS-OCT) device (IOLMaster 700). Setting Hanusch Hospital, Vienna, Austria. Design Prospective multicenter case series. Methods This study included patients with cataract in at least 1 eye. Two independent examiners performed Lens Opacities Classification System II (LOCS II) grading at the slitlamp independently. Corrected distance visual acuity, contrast sensitivity, and SS-OCT measurements were also performed. In addition, the phacoemulsification energy and time were recorded. To develop an objective SS-OCT-based cataract quantification system, all SS-OCT scans were segmented and the local pixel intensity unit of the lens ...

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      Mentions: Oliver Findl
    11. Contribution of Fourier-domain optical coherence tomography to the diagnosis of keratoconus progression

      Contribution of Fourier-domain optical coherence tomography to the diagnosis of keratoconus progression

      Purpose To determine the anatomic criteria for diagnosing keratoconus progression by corneal optical coherence tomography (OCT). Setting Quinze-Vingts National Ophthalmology Hospital, Paris, France. Design Prospective case series Methods Scanning-slit corneal topography (Orbscan II) and Fourier-domain corneal OCT (RTVue) were performed in eyes with mild to moderate keratoconus (progressive or nonprogressive [stable] ectasia) at each examination to assess the keratoconus. Disease progression was defined as an increase of at least 1.0 diopter (D) in the steepest keratometry (K) measurement over 6 months. Results Of the 134 eyes of 134 patients with mild to moderate keratoconus, 98 had had progressive ectasia ...

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    12. Accuracy of SS-OCT biometry compared with partial coherence interferometry biometry for combined phacovitrectomy with internal limiting membrane peeling

      Accuracy of SS-OCT biometry compared with partial coherence interferometry biometry for combined phacovitrectomy with internal limiting membrane peeling

      Purpose To evaluate the accuracy of a swept-source optical coherence tomography (SS-OCT) biometer compared with a standard partial coherence interferometry (PCI) biometer in terms of phacovitrectomy for vitreomacular pathology and cataract. Setting Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany. Design Prospective, nonrandomized, single center consecutive case series. Methods Patients with age-related cataract, regular corneal astigmatism less than 1.25 diopters (D) and a clinically significant vitreomacular pathology (epiretinal membrane [ERM], macular hole, or vitreomacular traction [VMT] syndrome) who had combined phacovitrectomy with internal limiting membrane peeling were enrolled. Objective and manifest refraction, corrected distance visual acuity, SS-OCT biometry, and PCI biometry ...

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    13. Evaluation of crystalline lens and intraocular lens tilt using a swept-source optical coherence tomography biometer

      Evaluation of crystalline lens and intraocular lens tilt using a swept-source optical coherence tomography biometer

      Purpose To evaluate crystalline lens and intraocular lens (IOL) tilt using a swept-source optical coherence tomography (SS-OCT) biometer (IOLMaster 700). Setting Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA. Design Retrospective case series. Methods The study patients were evaluated for 1) repeatability of the crystalline lens tilt measurement, 2) preoperative crystalline lens and postoperative IOL tilt in right eyes, 3) mirror symmetry between right eyes and left eyes, 4) the correlation between preoperative crystalline lens and postoperative IOL tilt, and 5) the correlation between the magnitude of lens tilt and ocular parameters. Results The study comprised 333 patients ...

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    14. Effect of phacoemulsification incision size on incision repair and remodeling: Optical coherence tomography assessment

      Effect of phacoemulsification incision size on incision repair and remodeling: Optical coherence tomography assessment

      Purpose To characterize the effect of incision size on corneal incision repair and remodeling over 3 months after cataract surgery. Setting Department of Ophthalmology, Auckland District Health Board, Auckland, New Zealand. Design Prospective case series. Methods Eyes having routine cataract surgery were randomized to receive 2.20 mm or 2.85 mm uniplanar clear corneal incisions. Anterior segment optical coherence tomography of incision thickness, length, width, gaping, and angle and specular microscopy of endothelial cell density (ECD), polymegathism, and pleomorphism were completed at baseline and 1, 7, 30, and 90 days postoperatively. Results Each incision group comprised 50 eyes (50 ...

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    15. Changes in retinal vasculature after phacoemulsification evaluated using optical coherence tomography angiography

      Changes in retinal vasculature after phacoemulsification evaluated using optical coherence tomography angiography

      Zhao et al. 1 describe changes in retinal vessel density and foveal avascular zone area after routine cataract surgery. These parameters were evaluated using optical coherence tomography (OCT) angiography, an exciting new imaging technology for noninvasive evaluation of the retinal microvasculature. 2 It has been reported that the foveal avascular zone, both in the superficial and deep retinal capillary plexus, varies significantly in size, even in normal healthy adults. 3

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    16. Preoperative spectral-domain optical coherence tomography in cataract surgery

      Preoperative spectral-domain optical coherence tomography in cataract surgery

      We read with interest the article by Abdelmassih et al.1 regarding the role and cost-effectiveness of preoperative spectral-domain optical coherence tomography (SD-OCT) in patients having cataract surgery. In their study, the macular SD-OCT was abnormal in 26.7% of eyes overall and in 17.5% of eyes when only anomalies not seen on fundus examination were taken into consideration.1 These results are somewhat different from those in previous studies reporting only pathological macular findings in patients having routine cataract surgery.

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    17. Can preoperative anterior segment optical coherence tomography predict posterior capsule rupture during phacoemulsification in patients with posterior polar cataract?

      Can preoperative anterior segment optical coherence tomography predict posterior capsule rupture during phacoemulsification in patients with posterior polar cataract?

      Purpose To determine whether preoperative assessment of posterior capsule integrity using anterior segment optical coherence tomography (AS-OCT) can predict posterior capsule dehiscence in patients with posterior polar cataract having phacoemulsification. Setting Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Pondicherry, India. Design Prospective observational study. Methods Patients with posterior polar cataract who had phacoemulsification between October 2012 and November 2013 were included in the study. Preoperative AS-OCT imaging was performed to assess the integrity of the posterior capsule. Anterior segment OCT images of the posterior capsule were graded as “intact” or “dehiscent.” Phacoemulsification was performed by the same surgeon who ...

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    18. Intraoperative optical coherence tomography measurements of aphakic eyes to predict postoperative position of 2 intraocular lens designs

      Intraoperative optical coherence tomography measurements of aphakic eyes to predict postoperative position of 2 intraocular lens designs

      Purpose To evaluate intraoperative anterior chamber depth (ACD) measurements of the aphakic eye to predict the postoperative ACD and compare 2 intraocular lens (IOL) designs. Setting Hanusch Hospital, Vienna, Austria. Design Prospective study. Methods In this prospective study, patients scheduled for cataract surgery received a plate-haptic IOL (Asphina, Carl Zeiss Meditec AG) or an open-loop haptic IOL (ZCB00, Johnson & Johnson). Preoperatively, optical biometry (IOLMaster 700, CZM, or Lenstar, Haag-Streit) was performed. Intraoperatively, a prototype setup was used to perform time-domain OCT scans of the anterior eye segment (Visante connected to OPMI Lumera 200, both CZM). The intraoperative ACD was measured ...

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      Mentions: Oliver Findl
    19. Preoperative spectral-domain optical coherence tomography in patients having cataract surgery

      Preoperative spectral-domain optical coherence tomography in patients having cataract surgery

      Purpose To evaluate the role and cost-effectiveness of preoperative spectral-domain optical coherence tomography (SD-OCT) in patients having cataract surgery. Setting Fondation Opthalmologique Adolphe de Rothschild, Paris, France. Design Retrospective case series. Methods All patients who had cataract surgery had macular and retinal nerve fiber layer SD-OCT preoperatively. A complete ophthalmologic examination was performed, including corrected near (CNVA) and corrected distance visual acuities, intraocular pressure (IOP), and a fundus examination. Results The study comprised 245 patients (401 eyes) with a mean age of 73.5 years ± 9.81 and a mean IOP of 15.6 ± 3.04 mm Hg. Of 107 ...

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    20. Changes in macular vasculature after uncomplicated phacoemulsification surgery: Optical coherence tomography angiography study

      Changes in macular vasculature after uncomplicated phacoemulsification surgery: Optical coherence tomography angiography study

      Purpose To use optical coherence tomography (OCT) angiography and a split-spectrum amplitude–decorrelation angiography algorithm to evaluate the changes in the macular vascular system after uncomplicated phacoemulsification. Setting Department of Ophthalmology, Eye and and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China. Design Prospective case series. Methods Patients with senile cataracts were included. Retinal vessel density and thickness at the macular area were checked by OCT at baseline and at 1 week, 1 month, and 3 months after cataract surgery. Results Thirty-two eyes (32 patients) were included in the final analysis. There was a significant increase in retinal ...

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      Mentions: Chunhui Jiang
    21. Corneal stromal demarcation line after 4 protocols of corneal crosslinking in keratoconus determined with anterior segment optical coherence tomography

      Corneal stromal demarcation line after 4 protocols of corneal crosslinking in keratoconus determined with anterior segment optical coherence tomography

      Purpose To use anterior segment optical coherence tomography (AS-OCT) to compare corneal stromal demarcation line depth after 4 treatment protocols of corneal crosslinking (CXL). Setting Eye Clinic, Sapienza University of Rome, Terracina (Latina), Italy. Design Prospective case series. Methods Patients with progressive keratoconus were delegated to one of the following CXL treatments: (1) conventional epithelium (epi)-off 3 mW/cm 2 according to the standard Dresden protocol (C-CXL group), (2) accelerated epi-off 10 mW/cm 2 (A-CXL group), (3) transepithelial epi-on 3 mW/cm 2 (TE-CXL group), or (4) transepithelial epi-on by iontophoresis 10 mW/cm 2 (I-CXL group). Two ...

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    22. New objective lens density quantification method using swept-source optical coherence tomography technology: Comparison with existing methods

      New objective lens density quantification method using swept-source optical coherence tomography technology: Comparison with existing methods

      Purpose To assess a new objective cataract grading method based on lens densitometry on swept-source optical coherence tomography (SS-OCT) scans provided by the IOLMaster 700. Settings Rothschild Foundation, Paris, France. Design Prospective case series. Methods All patients consulting for cataract evaluation who provided their consent to participate in the study were included. A history of eye surgery, corneal or retinal disorders, and ocular dryness were exclusion criteria. The average lens densitometry was measured with SS-OCT scans using ImageJ software. The ocular scatter index (OSI) measured with a double-pass aberrometer (Optical Quality Analysis System), the Pentacam nucleus staging (hereafter referred to ...

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    23. Microscope-integrated intraoperative optical coherence tomography-guided small-incision lenticule extraction: New surgical technique

      Microscope-integrated intraoperative optical coherence tomography-guided small-incision lenticule extraction: New surgical technique

      We describe the surgical technique of microscope-integrated intraoperative optical coherence tomography (OCT)-guided small-incision lenticule extraction. The technique enables manual tracking of surgical instruments and identification of the desired dissection plane. It also helps discern the relation between the dissector and the intrastromal lenticule. The dissection plane becomes hyperreflective on dissection, ensuring complete separation of the intrastromal lenticule from the overlying and underlying stroma. Inadvertent posterior plane entry, cap–lenticule adhesion, incomplete separation of the lenticule, creation of a false plane, and lenticule remnants may be recognized intraoperatively so corrective steps can be taken immediately. In cases with a hazy ...

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    24. New perspectives on the detection and progression of keratoconus

      New perspectives on the detection and progression of keratoconus

      Laser refractive surgery has increased markedly in recent years, making the detection of corneal abnormalities extremely relevant. For this reason, an accurate diagnosis of clinical or subclinical keratoconus is critical. Corneal topography is the primary diagnostic tool for keratoconus detection, and pachymetry data and corneal aberrations are also commonly used. Recently, tomographic measurements using optical coherence tomography and corneal biomechanical indices have been used. In incipient and subclinical keratoconus, the use of a single parameter as a diagnostic factor is not sufficiently accurate. In these cases, the use of algorithms and predictive models is necessary. In addition, determining whether the ...

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