Purpose To evaluate semiautomated surgical lens extraction procedures using the optical coherence tomography (OCT)–integrated Intraocular Robotic Interventional Surgical System. Setting Stein Eye Institute and Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, USA. Design Experimental study. Methods Semiautomated lens extraction was performed on postmortem pig eyes using a robotic platform integrated with an OCT imaging system. Lens extraction was performed using a series of automated steps including robot-to-eye alignment, irrigation/aspiration (I/A) handpiece insertion, anatomic modeling, surgical path planning, and I/A handpiece navigation. Intraoperative surgical supervision and human intervention were enabled by real-time OCT ...

In a recent article, Ouanezar et al.1 studied 134 keratoconus cases to define a new anatomic criterion for progressive keratoconus based on corneal optical coherence tomography (OCT). The authors stated that corneal thickness was better evaluated by OCT than by scanning-slit corneal topography on the basis of an interobserver repeatability comparison between the Orbscan IIz topographer (Bausch + Lomb Surgical, Inc.) and the RTVue Fourier-domain OCT device (Optovue, Inc.).

Purpose To determine the efficacy of femtosecond integrated anterior segment optical coherence tomography (ASOCT) for the detection of posterior capsular dehiscence in posterior polar cataracts (PPC). To evaluate the safety of phacoemulsification in these eyes undergoing Femtosecond Laser Assisted Cataract Surgery (FLACS). Setting Centre For Sight Group of Eye Hospitals, a chain of tertiary eye care hospitals in India. Design Prospective, interventional case series Methods The study included eyes with PPC undergoing FLACS using the Catalys femtosecond platform (Optimedica, CA, USA). Real time OCT guidance was utilized to image the posterior capsule (PC), which was then classified as “intact” or ...

Purpose To analyze the results of intraocular lens (IOL) power calculation using measurements by a swept-source optical coherence tomography (SS-OCT) optical biometer. Setting IRCCS G.B. Bietti Foundation, Rome, Italy. Design Evaluation of a diagnostic test instrument. Methods Preoperative measurements by the OA-2000 (Tomey Inc.) were taken in a consecutive series of patients undergoing cataract surgery with one IOL model (AcrySof SN60WF, Alcon Laboratories, Inc.). Measurements were entered into the following formulas: Barrett Universal II, EVO, Haigis, Hoffer Q, Holladay 1, Holladay 2, Holladay 2 with axial length adjustment, Kane, Olsen, Panacea, SRK/T, T2 and VRF. When refraction was ...

Purpose To confirm the presence of incomplete vitreo-lenticular adhesion via microscope-integrated intraoperative optical coherence tomography (iOCT) during cataract surgery and via diagnostic spectral-domain OCT postoperatively. Setting S. Fyodorov Eye Microsurgery Complex State Institution, Moscow, Russia; Design Prospective, non-interventional, single-center study. Methods Clinical characteristics and surgical videos of 27 patients (28 eyes) who underwent cataract surgery were documented. Real-time iOCT integrated into the surgical microscope was directed to view the retro-lenticular anatomy at the end of the surgery. Postoperatively, spectral-domain OCT was also performed. Results Berger’s space could be identified in 21 cases (75%) intraoperatively via iOCT and in 23 ...

Purpose To assess an upgraded version of our objective cataract grading method based on lens densitometry on Swept-Source Optical Coherence Tomography (SS-OCT) scans provided by the IOLMaster 700. Settings Single centre study at the Rothschild Foundation, Paris, France. Design Prospective cross-sectional study Methods All patients consulting for cataract evaluation and consenting to study participation were included. History of previous ocular surgery, cornea or retina disorders, and ocular dryness were exclusion criteria. The average lens densitometry (ALD) was measured on SS-OCT scans provided by the IOLMaster 700 using our algorithm developed on MATLAB® software. The ocular scatter index (OSI) was measured ...

After cataract surgery, a frequent challenge faced by the anterior segment surgeon is posterior capsule opacification (PCO). Therefore, it is necessary to tackle this intraoperatively by thoroughly removing the lens capsule epithelial cells. 1 A square-edged intraocular lens (IOL) optic has also been shown to reduce the occurrence of PCO. 1 Determining the actual changes along the square edges of the IOL and the capsule junction is important in understanding why PCO develops.

P urpose To examine the repeatability and reproducibility of biometry provided by a new anterior-posterior segment spectral-domain optical coherence tomography (SD-OCT) device (Revo NX, Optopol Technology Sp. z o.o., Zawiercie, Poland), and to compare them to those provided by a validated low-coherence optical reflectometry (LCOR) biometer, the Lenstar LS 900. Setting Hygeia Clinic, Gdańsk, Poland Design Prospective evaluation of diagnostic test. Methods Axial length (AL), lens thickness (LT), central corneal thickness (CCT) and anterior chamber depth (ACD, corneal epithelium to lens) were measured in 63 eyes of 63 patients. Two skilled operators, in random order, obtained three measurements with ...

The stated purpose of the study by Brás et al. 1 was to develop and evaluate a cataract quantification method using a swept-source optical coherence tomography (SS-OCT) device (IOLMaster 700, Carl Zeiss Meditec AG). We were disappointed that the authors failed to cite our article published in your journal in December 2017, 2 well before the submission of their paper at the end of March 2018. Our abstract explicitly states the purpose of our study: “To assess a new objective cataract grading method based on lens densitometry on swept-source optical coherence tomography…scans provided by the IOLMaster 700.” We ...

In the study by Pavan Kumar et al., 1 the authors addressed an important issue for clinical practice and reported that anterior segment optical coherence tomography (AS-OCT) has high sensitivity (100%) and specificity (94.9%) for predicting posterior capsule rupture during phacoemulsification surgery in eyes with posterior polar cataract.

We modified the posterior segment optical coherence tomography (OCT) process to image anterior segment structures by keeping a 20.0 diopter lens along its aperture (Figure 1, A ). We were measuring the central corneal thickness using this technique and we noticed some empty pockets within the anterior lens matter. We discuss these findings in 2 cases.

Purpose To report the level of agreement, repeatability and correlation of two swept-source optical coherence tomography (SS-OCT) biometers, the IOLMaster 700 (Carl Zeiss Meditec AG, Germany) (reference biometer) and the Argos (Movu, Inc.) (new biometer), in terms of axial length (AL), keratometric mean (mean K), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and corneal diameter (CD). Setting Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. Design Retrospective, comparative case-series. Methods Each participant underwent SS-OCT biometry with the reference and new biometer. In addition to reporting the statistical results derived from both eyes, this study included ...

Purpose To investigate the safety and efficacy of the intra-operative use of a triphasic polymeric gel as corneal coating during cataract surgery and its effect on postoperative ocular comfort Setting Eye Clinic, University of Florence, Italy Design Longitudinal observational retrospective study Methods Data of 25 patients who received an application of polysaccharide blend on corneal surface (EyeDro – Alchimia s.r.l., hydroxypropyl methylcellulose, xanthan gum and carrageenan) and of 27 eyes who received balanced salt solution (BSS) during phacoemulsification surgery were analyzed. Central Corneal Thickness (CCT) and Epithelial Thickness (ET) were examined using Anterior Segment Optical Coherence Tomography (AS-OCT) and ...

Purpose To assess the repeatability and agreement of anterior segment measurements between an optical biometer (IOLMaster 700) using swept-source optical coherence tomography and a Scheimpflug–Placido tomographer (Sirius) in patients scheduled for corneal refractive surgery. Setting Eye Hospital of Wenzhou Medical University, Zhejiang, China. Design Prospective case series. Methods The parameters, including the central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, keratometry (K) values, astigmatism, J0 (Jackson cross-cylinder with axes at 180 degree and 90 degrees) and J45 vectors (Jackson cross-cylinder with axes at 45 degrees and 135 degrees), and horizontal corneal diameter, were measured 3 times per ...

Purpose The aim of this retrospective study was to determine if the vault measurement, after hole implantable collamer lens (hole ICL, KS-AquaPORT) surgery, can be predicted by angle-to-angle (ATA) and white-to-white (WTW) measurements on anterior segment (AS) optical coherence tomography (OCT). Setting Sanno Hospital, Tokyo, Japan. Design Retrospective case series. Methods The study included 44 eyes (23 patients) that were observed for 3 months following hole ICL implantation for myopia or myopic astigmatism. The mean patient age and preoperative spherical equivalent, ATA, and WTW values were 36.2±8.8 years, -6.23±3.41 D, 12.03±0.40 ...

Purpose To assess the prevalence of macular abnormalities not suspected by the biomicroscopic fundus exam and identified only by macular optical coherence tomography (OCT) in the preoperative evaluation for cataract surgery in a large series of Brazilian patients. Setting Private practice, Recife, Brazil. Design Retrospective case series. Methods All eyes that underwent cataract surgery by a single physician between August 2014 and July 2016 were eligible. We excluded eyes with a previous diagnosis of macular abnormalities, with a suspicious biomicroscopic fundus exam, and those without OCT results. Based on the preoperative macular OCT, patients were subdivided in two groups: those ...

Purpose Role of anterior segment optical coherence tomography for safer management of mature white cataracts Setting Patients with mature white cataract attending the outpatient department of a tertiary eye care hospital, aspiring to get cataract surgery done, were scheduled for elective phacoemulsification and intraocular lens implantation by two surgeons during the time period of October 2017 till March 2018. Design A prospective interventional study of 30 patients. Methods All patients with mature cataracts and absence of any retinal pathology, underwent anterior segment optical coherence tomography (ASOCT) to assess the presence or absence of intra-lenticular subcapsular fluid pockets. The patients with ...

Purpose To develop and evaluate a cataract quantification method using a swept-source optical coherence tomography (SS-OCT) device (IOLMaster 700). Setting Hanusch Hospital, Vienna, Austria. Design Prospective multicenter case series. Methods This study included patients with cataract in at least 1 eye. Two independent examiners performed Lens Opacities Classification System II (LOCS II) grading at the slitlamp independently. Corrected distance visual acuity, contrast sensitivity, and SS-OCT measurements were also performed. In addition, the phacoemulsification energy and time were recorded. To develop an objective SS-OCT-based cataract quantification system, all SS-OCT scans were segmented and the local pixel intensity unit of the lens ...

Purpose To determine the anatomic criteria for diagnosing keratoconus progression by corneal optical coherence tomography (OCT). Setting Quinze-Vingts National Ophthalmology Hospital, Paris, France. Design Prospective case series Methods Scanning-slit corneal topography (Orbscan II) and Fourier-domain corneal OCT (RTVue) were performed in eyes with mild to moderate keratoconus (progressive or nonprogressive [stable] ectasia) at each examination to assess the keratoconus. Disease progression was defined as an increase of at least 1.0 diopter (D) in the steepest keratometry (K) measurement over 6 months. Results Of the 134 eyes of 134 patients with mild to moderate keratoconus, 98 had had progressive ectasia ...

Purpose To evaluate the accuracy of a swept-source optical coherence tomography (SS-OCT) biometer compared with a standard partial coherence interferometry (PCI) biometer in terms of phacovitrectomy for vitreomacular pathology and cataract. Setting Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany. Design Prospective, nonrandomized, single center consecutive case series. Methods Patients with age-related cataract, regular corneal astigmatism less than 1.25 diopters (D) and a clinically significant vitreomacular pathology (epiretinal membrane [ERM], macular hole, or vitreomacular traction [VMT] syndrome) who had combined phacovitrectomy with internal limiting membrane peeling were enrolled. Objective and manifest refraction, corrected distance visual acuity, SS-OCT biometry, and PCI biometry ...

Purpose To evaluate crystalline lens and intraocular lens (IOL) tilt using a swept-source optical coherence tomography (SS-OCT) biometer (IOLMaster 700). Setting Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA. Design Retrospective case series. Methods The study patients were evaluated for 1) repeatability of the crystalline lens tilt measurement, 2) preoperative crystalline lens and postoperative IOL tilt in right eyes, 3) mirror symmetry between right eyes and left eyes, 4) the correlation between preoperative crystalline lens and postoperative IOL tilt, and 5) the correlation between the magnitude of lens tilt and ocular parameters. Results The study comprised 333 patients ...

Purpose To characterize the effect of incision size on corneal incision repair and remodeling over 3 months after cataract surgery. Setting Department of Ophthalmology, Auckland District Health Board, Auckland, New Zealand. Design Prospective case series. Methods Eyes having routine cataract surgery were randomized to receive 2.20 mm or 2.85 mm uniplanar clear corneal incisions. Anterior segment optical coherence tomography of incision thickness, length, width, gaping, and angle and specular microscopy of endothelial cell density (ECD), polymegathism, and pleomorphism were completed at baseline and 1, 7, 30, and 90 days postoperatively. Results Each incision group comprised 50 eyes (50 ...

Zhao et al. 1 describe changes in retinal vessel density and foveal avascular zone area after routine cataract surgery. These parameters were evaluated using optical coherence tomography (OCT) angiography, an exciting new imaging technology for noninvasive evaluation of the retinal microvasculature. 2 It has been reported that the foveal avascular zone, both in the superficial and deep retinal capillary plexus, varies significantly in size, even in normal healthy adults. 3

We read with interest the article by Abdelmassih et al.1 regarding the role and cost-effectiveness of preoperative spectral-domain optical coherence tomography (SD-OCT) in patients having cataract surgery. In their study, the macular SD-OCT was abnormal in 26.7% of eyes overall and in 17.5% of eyes when only anomalies not seen on fundus examination were taken into consideration.1 These results are somewhat different from those in previous studies reporting only pathological macular findings in patients having routine cataract surgery.