1. 1-4 of 4
    1. Coronary Plaque Rupture in Stable Coronary Artery Disease and Non-ST Segment Elevation Myocardial Infarction: An Optical Coherence Tomography Study

      Coronary Plaque Rupture in Stable Coronary Artery Disease and Non-ST Segment Elevation Myocardial Infarction: An Optical Coherence Tomography Study

      Background. Plaque rupture (PR) is the main cause of coronary thrombosis in non-ST segment elevation myocardial infarction (NSTEMI), but can be found in stable coronary artery disease (CAD). Our study compared the morphology and local inflammatory activity of ruptured plaques between stable CAD and NSTEMI patients using frequency-domain optical coherence tomography (FD-OCT). Methods. We retrospectively evaluated 70 plaques with PR at the FD-OCT (25 in stable CAD patients and 45 in NSTEMI patients). Main clinical, angiographic, and morphological features were compared. Results. Besides an overall equivalence in clinical and angiographic features (except for more smokers among NSTEMI patients), some important ...

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    2. Atherogenesis in Native Coronary Segments and In-Stent Neoatherogenesis Beyond Three Years After First-Generation Drug-Eluting Stent Implantation: Angiographic and Optical Coherence Tomography Study

      Atherogenesis in Native Coronary Segments and In-Stent Neoatherogenesis Beyond Three Years After First-Generation Drug-Eluting Stent Implantation: Angiographic and Optical Coherence Tomography Study

      Objectives: The mechanisms underlying the development of neoatherosclerosis following stent implantation remain to be further elucidated. The aim of this study was to investigate the association between subclinical in-stent neoatherosclerosis (NA) and atherosclerosis progression of native coronary segments in patients with chronic coronary syndrome 3 and 9 years after first-generation drug-eluting stent implantation. Methods: This is a prespecified analysis of the prospective cohort study evaluating long-term neointimal healing in consecutive patients undergoing elective percutaneous coronary intervention with sirolimus-eluting stent (SES) or paclitaxel-eluting stent (PES) implantation. Quantitative coronary angiography (QCA) was evaluated in non-stented coronary segments. Results: Forty-three patients underwent optical ...

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    3. Longitudinal Stent Deformation: Insights Provided by Optical Coherence Tomography

      Longitudinal Stent Deformation: Insights Provided by Optical Coherence Tomography

      A 60-year-old man underwent elective percutaneous coronary intervention (PCI) for stable coronary artery disease. The angiogram showed Medina 1,1,1 disease at the bifurcation of the mid left anterior descending (LAD) coronary artery and major diagonal and provisional bifurcation stenting was planned. The diagonal branch was protected with a guidewire and a 2.75 x 32 mm drug-eluting stent was implanted in the mid LAD. Proximal optimization was done using a 3 mm non-compliant (NC) balloon. The sidebranch was recrossed through the distal stent strut. During removal of the trapped sidebranch guidewire, the guide catheter was inadvertently sucked into ...

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    4. Complete Coronary Stent Removal After Optical Coherence Tomography Performance 8 Months Later for Device Entrapment: A Scary Challenge

      Complete Coronary Stent Removal After Optical Coherence Tomography Performance 8 Months Later for Device Entrapment: A Scary Challenge

      A 62-year-old man presented with unstable angina 8 months earlier. The patient underwent percutaneous coronary intervention (PCI) of the proximal left anterior descending coronary artery with a 2.75 x 15 mm cobalt-chromium sirolimus-eluting stent (Biotronik AG) ( Figures 1A-1C ). The patient was discharged uneventfully on aspirin and clopidogrel. Eight months later, the patient was admitted for non-ST segment elevation myocardial infarction (STEMI). Coronary angiography showed late stent thrombosis at the origin of the first septal branch ( Figure 1D ), probably due to turbulent flow at the level of the septal and diagonal branches and proximal stent malapposition. Optical coherence tomography (OCT ...

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    1-4 of 4
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