1. Articles from HCPLive

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    1. Daily Self-Imaging with Home OCT Viable Among Patients with nAMD

      Daily Self-Imaging with Home OCT Viable Among Patients with nAMD

      New findings suggest daily home optical coherence tomography (OCT) imaging has feasibility among patients with neovascular age-related macular degeneration (nAMD) . The home OCT additionally allowed for detailed graphical and mathematical analyses of retinal fluid volume trajectories, including novel parameters in order to inform clinical decision making. “It demonstrated good agreement with human expert grading for retinal fluid identification and excellent agreement with the in-clinic OCT scans,” wrote study author Jeffrey Heier, MD, Ophthalmic Consultants of Boston. The prospective, observational study aimed to validate the performance of a home OCT system (Notal Vision Home OCT) for daily self-imaging at home and ...

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      Mentions: Notal Vision
    2. RNFL Thinning Linked to Poor Visual Acuity in Preterm Infants

      RNFL Thinning Linked to Poor Visual Acuity in Preterm Infants

      Findings from a recent observational study suggest the evaluation of retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) may help identify preterm infants at risk for poor vision outcomes. Data show the thinning of the RNFL across the papillomacular bundle (PMB) had associations with poorer 9-month visual acuity, found independent of birth weight, gestational age, need for retinopathy of prematurity (ROP) treatment, and macular microanatomy. “Our findings suggest that RNFL thinning across the PMB may be an early biomarker of global disruptions in neurodevelopment that put preterm infants at risk for poorer vision outcomes,” wrote study author ...

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      Mentions: Duke University
    3. Predictive AI Model Identifies nAMD Treatment Response Biomarkers

      Predictive AI Model Identifies nAMD Treatment Response Biomarkers

      An artificial intelligence (AI) method designed to predict visual outcomes via a treat-and-extend (T&E) regimen of anti-VEGF therapy ranibizumab in patients with neovascular age-related macular degeneration (nAMD) showed particular benefit of defined—and easily accessible—biomarkers. The new data, presented at the Association for Research in Vision and Ophthalmology (ARVO) 2022 Meeting this week, may contribute the developing field of AI and machine learning for optimizing chronic retinal disease management. Led by Hrvoje Bogunovic, PhD, director of the Christian Doppler Lab for Artificial Intelligence in Retina and associates director of the Laboratory for Ophthalmic Image Analysis at the Medical ...

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    4. Rapid Vessel Density Loss Linked to Faster Rate of Visual Field Loss

      Rapid Vessel Density Loss Linked to Faster Rate of Visual Field Loss

      Rapid vessel density loss was associated with a higher concurrent and subsequent rates of visual field loss during an extended period in patients with suspected glaucoma and primary-open angle glaucoma (POAG). After dividing the eyes into fast and slow optical coherence tomography angiography (OCTA), these findings in a recent cohort study found a signficantly greater rate of visual field mean deviation loss was faster for fast OCTA progressors during a 4-year follow-up period. “This finding is clinically relevant if subsequent prospective studies confirm that fast progressors identified by OCTA are at higher risk of functional loss and may need more ...

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      Mentions: UCSD
    5. Deep Learning Could Transform Ophthalmology

      Deep Learning Could Transform Ophthalmology

      Ophthalmology could be the next specialty to look into utilizing new deep learning technology to screen and diagnose patients with ocular disorders. Nihaal Mehta, MD A team, led by Nihaal Mehta, MD, New England Eye Center, Tufts Medical Center, determined whether a model-to-data deep learning approach without needing to transfer any data can be applied in ophthalmology. In the single-center cross-sectional study, the investigators examined patients with active exudative age-related macular degeneration (AMD) who underwent optical coherence tomography (OCT) at the New England Eye Center between August 2018 and February 2019

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