1. Articles from annals.com

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    1. Combined Optical Coherence Tomography and Endobronchial Ultrasonography for Laser-Assisted Treatment of Postintubation Laryngotracheal Stenosis

      Combined Optical Coherence Tomography and Endobronchial Ultrasonography for Laser-Assisted Treatment of Postintubation Laryngotracheal Stenosis

      We describe the use of combined optical coherence tomography (OCT) and endobronchial ultrasonography (EBUS) to identify the residual hypertrophic tissues and persistent inflammation that are known contributors to stricture recurrence after laser-assisted mechanical dilation (LAMD) of laryngotracheal stenosis (LTS). Methods : Commercially available high-frequency EBUS (approximately 100-μm resolution) and time-domain OCT (approximately 10- to 20-μm resolution) systems were used to visualize airway wall microstructures in the area of hypertrophic tissue formation before and after LAMD in 2 patients with complex circumferential postintubation LTS. Results : Before LAMD, EBUS revealed a homogeneous layer consistent with hypertrophic tissue overlying a hyperechogenic layer ...

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      Mentions: UC Irvine
    2. Quantitative Distinction of Unique Vocal Fold Subepithelial Architectures Using Optical Coherence Tomography

      Quantitative Distinction of Unique Vocal Fold Subepithelial Architectures Using Optical Coherence Tomography

      Objectives : The primary objective of this study was to quantitatively analyze ex vivo porcine, fetal human, and adult human vocal folds by use of optical coherence tomography (OCT). A secondary objective was to quantitatively discriminate among 1-, 2-, and 3-layer lamina propria structures. Methods : We performed an analysis of the vocal folds of 10 adult pig, 3 adult human, and 2 fetal human vocal fold specimens using OCT and histologic techniques. We present a quantitative comparison of the OCT results and histologic findings. Results : We found that OCT allowed for the visualization of the subepithelial vocal fold architecture of all ...

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    3. Optical Coherence Tomography–Enhanced Microlaryngoscopy: Preliminary Report of a Noncontact Optical Coherence Tomography System Integrated With a Surgical Microscope

      Objectives: Optical coherence tomography (OCT) is a new imaging modality that uses near-infrared light to produce cross-sectional images of tissue with a resolution approaching that of light microscopy. We have previously reported use of OCT imaging of the vocal folds (VFs) during direct laryngoscopy with a probe held in contact or near-contact with the VFs. This aim of this study was to develop and evaluate a novel OCT system integrated with a surgical microscope to allow hands-free OCT imaging of the VFs, which could be performed simultaneously with microscopic visualization. Methods: We performed a prospective evaluation of a new method ...
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    4. Optical Coherence Tomography Imaging of the Inner Ear: A Feasibility Study With Implications for Cochlear Implantation

      Cochlear implantation is now being performed in ears with residual hearing. Those implant recipients who keep residual hearing may benefit from improved pitch resolution through both electrical and acoustic hearing. Preservation of cochlear function after implantation is a challenging task for the surgeon. Current topics of hearing preservation research include electrode design and surgical technique. To maintain hearing, surgeons strive to create a cochleostomy and place the electrode in a minimally traumatic fashion. In this study, we examine a novel catheter-based real-time imaging modality with 10- to 15-μm resolution, optical coherence tomography (OCT), on the inner ear. We demonstrate the ...
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    5. Optical Coherence Tomography of the Newborn Airway

      Objectives: Acquired subglottic stenosis in a newborn is often associated with prolonged endotracheal intubation. This condition is generally diagnosed during operative endoscopy after airway injury has occurred. Unfortunately, endoscopy is unable to characterize the submucosal changes observed in such airway injuries. Other modalities, such as magnetic resonance imaging, computed tomography, and ultrasound, do not possess the necessary level of resolution to differentiate scar, neocartilage, and edema. Optical coherence tomography (OCT) is an imaging modality that produces high-resolution, cross-sectional images of living tissue (8 to 20 μm). We examined the ability of this noninvasive technique to characterize the newborn airway in ...
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    1-5 of 5
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