1. 1-7 of 7
    1. Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography (Thesis)

      Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography (Thesis)

      Vision is worsening on a global scale. Myopia, a visual condition where distant objects appear blurry, is increasing in prevalence at an alarming rate. This condition typically starts during childhood and progressively worsens, potentially leading to more severe visual conditions if left unchecked. Currently, the best treatment method to slow myopic progression is heavily debated as the etiology of myopia is not fully understood. The development of effective long-term solutions require a better understanding of how vision changes with age. The cornea and lens, the length of the human eye, and the surrounding ocular media dictate visual quality. Extensive studies ...

      Read Full Article
    2. Quantification of Ciliary Muscle Function through Morphological Analysis of Optical Coherence Tomography Images (Thesis)

      Quantification of Ciliary Muscle Function through Morphological Analysis of Optical Coherence Tomography Images (Thesis)

      s we grow older, we lose our ability to accommodate, or focus from far to near, in a condition called presbyopia. Presbyopia is an issue in our everyday life, complicating routine tasks such as using smartphones or reading street signs while driving. To develop effective therapies to treat presbyopia, we need to understand the changes in the eye that occur with age. We need to be able to observe the eye in vivo as accommodation occurs. The present dissertation focuses on the part of the eye responsible for starting the mechanics of accommodation, the ciliary muscle. Imaging of the muscle ...

      Read Full Article
    3. High Resolution Wide Field-of-View Optical Coherence Tomography For 3D Imaging (Thesis)

      High Resolution Wide Field-of-View Optical Coherence Tomography For 3D Imaging (Thesis)

      Optical coherence tomography (OCT) is a noninvasive, cross-sectional, and three-dimensional (3D) tomographic imaging modality. It offers subsurface deeper penetration depth and larger scan area than confocal microscopy as well as higher resolution than ultrasound imaging, very suitable for 3D in vivo imaging of eyes, skins, blood vessels, and other non-biomedical samples. However, there is a trade-off problem among lateral resolution, lateral field of view (FOV), and axial imaging depth, limiting the performance of OCT systems. In this dissertation, we report our studies to solve these problems and to make the OCT a competitive tool for a variety of 3D imaging ...

      Read Full Article
    4. Reflectometry and Optical Coherence Tomography for Non-invasive High Resolution Tear Film Thickness Evaluation and Ophthalmic Imaging (Thesis)

      Reflectometry and Optical Coherence Tomography for Non-invasive High Resolution Tear Film Thickness Evaluation and Ophthalmic Imaging (Thesis)

      Dry eye debilitates the patients physically, limit their ability to perform daily tasks, cause clinical depression, and compromise quality of life. Accurate diagnosis of the dry eye and the research on the pathological mechanism and treatment both depend largely on the available measurement techniques. The development of new measurement techniques helps better understanding of the disease and paves the way for accurate early diagnosis and better treatment. The purpose of this study was to develop additional tools in ophthalmic study for non-invasive high resolution tear film thickness evaluation and eye imaging. Optical coherence tomography (OCT) is a non-invasive imaging technology ...

      Read Full Article
    5. Evaluation of the Crystalline Lens Gradient Refractive Index using Laser Ray Tracing and Optical Coherence Tomography (Thesis)

      Evaluation of the Crystalline Lens Gradient Refractive Index using Laser Ray Tracing and Optical Coherence Tomography (Thesis)

      The human crystalline lens is a complex and intricate structure that continuously grows throughout our lifetime. The crystalline lens has a non-uniform distribution of protein concentrations which produces an optical gradient within the lens in both the optical and equatorial axes. This gradient refractive index is a unique property of the crystalline lens that significantly contributes to its optical power and aberrations. The objective of this dissertation is to gain a better understanding of the relationship between the crystalline lens shape, its non-uniform gradient refractive index, the lens optical power and aberrations, and their changes with accommodation and age. The ...

      Read Full Article
    6. Design and Fabrication of Optical Polymer Waveguide Devices for Optical Interconnects and Integrated Optical Coherence Tomography (Thesis)

      Design and Fabrication of Optical Polymer Waveguide Devices for Optical Interconnects and Integrated Optical Coherence Tomography (Thesis)

      Optical interconnects is a promising technique to boost the speed of electronic systems through replacing high speed electrical data buses using optical ones. Optical coherence tomography is an attractive imaging technique that has been widely used in medical imaging applications with capability of high resolution subsurface cross sectional imaging in living tissues. Both the optical interconnects and the optical coherence tomography imaging may benefit from the use of integrated optics technology in particular polymer waveguides that can be designed and fabricated to improve the device capability, system compactness, and performance reliability. In this dissertation, we first present our innovative design ...

      Read Full Article
    7. Improving the Quantitative Assessment of Intraretinal Features by Determining both Structural and Optical Properties of the Retinal Tissue with Optical Coherence Tomography (Thesis)

      Improving the Quantitative Assessment of Intraretinal Features by Determining both Structural and Optical Properties of the Retinal Tissue with Optical Coherence Tomography (Thesis)

      The goal of this project is to obtain quantitative assessments of intraretinal features by determining the structural and optical properties of retinal tissue with optical coherence tomography. To accomplish this goal, structural and optical properties, in addition to thickness measurements, were extracted from OCT-based images and were used for the discrimination of DM eyes with and without DR from healthy eyes. First, structural parameters including the thickness, fractal dimension, energy, entropy, correlation and contrast were evaluated for each intraretinal layer using various image processing techniques such as speckle noise removal, retinal segmentation and blood vessel shadow removal. In addition, optical ...

      Read Full Article
    1-7 of 7
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks