1. 73-96 of 114 « 1 2 3 4 5 »
    1. Tear Meniscus Evaluation Using Optical Coherence Tomography in Dry Eye Patients

      Tear Meniscus Evaluation Using Optical Coherence Tomography in Dry Eye Patients

      Purpose To evaluate the tear meniscus in aqueous tear-deficient dry eye patients using Fourier-domain optical coherence tomography (FD-OCT) and to investigate the clinical usefulness of tear meniscus values. Methods The present study included 79 aqueous tear-deficient dry eyes and 50 normal eyes. Tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA) were imaged using FD-OCT and measured with computer calipers. Schirmer's test, tear break-up time, and corneal fluorescein staining were also performed and the correlations between the tests were analyzed. Additionally, the diagnostic power of tear meniscus values was compared using area under the receiver ...

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    2. Optical coherence tomography for the diagnosis and evaluation of human otitis media

      Optical coherence tomography for the diagnosis and evaluation of human otitis media

      We report the application of optical coherence tomography (OCT) to the diagnosis and evaluation of otitis media (OM). Whereas conventional diagnostic modalities for OM, including standard and pneumatic otoscopy, are limited to visualizing the surface of the tympanic membrane (TM), OCT effectively reveals the depth-resolved microstructure below the TM with very high spatial resolution, with the potential advantage of its use for diagnosing different types of OM. We examined the use of 840-nm spectral domain-OCT (SD-OCT) clinically, using normal ears and ears with the adhesive and effusion types of OM. Specific features were identified in two-dimensional OCT images of abnormal ...

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    3. Detecting the Progression of Normal Tension Glaucoma: A Comparison of Perimetry, Optic Coherence Tomography, and Heidelberg Retinal Tomography

      Detecting the Progression of Normal Tension Glaucoma: A Comparison of Perimetry, Optic Coherence Tomography, and Heidelberg Retinal Tomography

      Purpose We compared the abilities of Stratus optical coherence tomography (OCT), Heidelberg retinal tomography (HRT) and standard automated perimetry (SAP) to detect the progression of normal tension glaucoma (NTG) in patients whose eyes displayed localized retinal nerve fiber layer (RNFL) defect enlargements. Methods One hundred four NTG patients were selected who met the selection criteria: a localized RNFL defect visible on red-free fundus photography, a minimum of five years of follow-up, and a minimum of five reliable SAP, Stratus OCT and HRT tests. Tests which detected progression at any visit during the 5-year follow-up were identified, and patients were further ...

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    4. Structural Analysis of Different Incision Sizes and Stromal Hydration in Cataract Surgery Using Anterior Segment Optical Coherence Tomography

      Structural Analysis of Different Incision Sizes and Stromal Hydration in Cataract Surgery Using Anterior Segment Optical Coherence Tomography

      Purpose To analyze healing changes of corneal wounds of different corneal incision sizes with or without stromal hydration in cataract surgery using anterior segment optical coherence tomography. Methods Cataract surgeries were performed by a single surgeon and 2.2- and 2.8-mm corneal incisions were made using a diamond blade (ME-759; Meyco, Biel-Bienne, Swiss). Patients were divided into four groups according to incision size (2.2 and 2.8 mm), and with/without stromal hydration. Fifteen eyes were assigned to each group and incision wounds were measured using anterior segment optical coherence tomography at 2 hours, 1 day, 1 week ...

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    5. The Evaluation of Prognostic Factors after Vitrectomy for Lamellar Macular Hole Using Optical Coherence Tomography

      The Evaluation of Prognostic Factors after Vitrectomy for Lamellar Macular Hole Using Optical Coherence Tomography

      Purpose To evaluate the prognostic factors that predict visual outcome after vitrectomy for lamellar macular hole using optical coherence tomography (OCT). Methods This study included 26 eyes that underwent pars plana vitrectomy, epiretinal membrane removal, and internal limiting membrane peeling for lamellar macular hole. The maximum parafoveal thickness, maximum height and diameter of lamellar macular hole, maximum height and diameter of intraretinal splitting, thinnest foveal floor thickness, and inner segment/outer segment disruption length on preoperative OCT image were investigated for prognostic factors that predict visual outcome. Results The mean follow-up period was 32.2 months and the mean best ...

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    6. Difference of GCIPL Thickness of Diabetes and Normal Eyes in Spectral Domain OCT

      Difference of GCIPL Thickness of Diabetes and Normal Eyes in Spectral Domain OCT

      Purpose To analyze the difference of the ganglion cell-inner plexiform layer (GCIPL) thickness in diabetic and normal eyes of patients using spectral domain optical coherence tomography (OCT) (Carl Zeiss Meditec, Dublin, CA, USA). Methods The authors compared and analyzed the difference of the GCIPL thickness measured with spectral domain optical coherence tomography (OCT) in 42 diabetic and 92 normal subjects. Results The study subjects were divided into 3 groups: 92 normal subjects, 22 diabetic patients without diabetic retinopathy, and 26 diabetic patients with diabetic retinopathy. Presence of diabetes mellitus (DM) or diabetic retinopathy did not influence the retinal nerve fiber ...

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    7. Foveal Shape According to Age and Gender Using Spectral Domain Optical Coherence Tomography

      Foveal Shape According to Age and Gender Using Spectral Domain Optical Coherence Tomography

      Purpose To compare foveal shapes in Koreans according to age and gender using spectral domain optical coherence tomography (SD-OCT). Methods This study included 230 eyes of 115 healthy adults. The subjects were divided into three groups: group 1 (20-39 years of age), group 2 (40-59 years of age) and group 3 (60-79 years of age). Using spectralis OCT, we measured central foveal thickness (CFT), regional maximal retinal thickness (MRT), pit diameter and pit depth and compared the differences between the groups. Results The MRT of the superior, inferior and nasal sides in group 1 was higher than in groups 2 ...

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    8. Predictive Findings of Visual Outcome in Spectral Domain Optical Coherence Tomography after Ranibizumab Treatment in Age-related Macular Degeneration

      Predictive Findings of Visual Outcome in Spectral Domain Optical Coherence Tomography after Ranibizumab Treatment in Age-related Macular Degeneration

      Purpose To investigate which spectral domain optical coherence tomography (SD-OCT) findings predict visual outcome after anti-vascular endothelial growth factor (VEGF) treatment in neovascular age-related macular degeneration (NV-AMD). Methods We reviewed the medical records of patients with treatment-naïve NV-AMD who underwent three or more consecutive anti-VEGF injections. The patients were divided into three groups according to their changes of visual acuity (VA); improved (group I), static (group S), or worsened (group W). We assessed the incidences and values of all available SD-OCT findings of these groups, compared these findings between the three groups and compared the initial values with the ...

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    9. Choroid in Myopic Choroidal Neovascularization Measured Using SD-OCT

      Choroid in Myopic Choroidal Neovascularization Measured Using SD-OCT

      Purpose Using the spectral domain optical coherence tomography (SD-OCT), we studied the difference in the choroidal morphology between the choroidal neovascularization (CNV) area and the area surrounding CNV. Methods This retrospective study consisted of 19 patients with myopic CNV lesion in eye; fellow eyes were used as controls. All eyes were analyzed by measuring the choroidal thickness and large choroidal vessel size using SD-OCT. Eyes with CNV were divided into groups; the neovascular lesion was defined as group 1, the surrounding area as group 2. Subfovea of the fellow eye was defined as group 3. Results The choroidal thickness was ...

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    10. Difference in Subfoveal Choroidal Thickness between Two Spectral-Domain Optical Coherence Tomography Systems

      Difference in Subfoveal Choroidal Thickness between Two Spectral-Domain Optical Coherence Tomography Systems

      Purpose To determine the difference in subfoveal choroidal thickness between two spectral-domain optical coherence tomography (SD-OCT) systems in normal eyes and eyes with retinal diseases. Methods Thirty-three normal eyes and 49 eyes with retinal disease (13 eyes with diabetic retinopathy, 28 eyes with epiretinal membrane and eight eyes with macular hole) were enrolled in the study. Subfoveal choroidal thicknesses were measured by 3 observers using the enhanced depth imaging technique of Heidelberg Spectralis® and the high-definition five-line raster scan of Cirrus HD-OCT® using calipers within the program. Differences between the measured values were analyzed with a paired t -test in ...

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    11. Influence of Image Compression on the Interpretation of Optical Coherence Tomography in Diabetic Macular Edema

      Influence of Image Compression on the Interpretation of Optical Coherence Tomography in Diabetic Macular Edema

      Purpose To evaluate the influence of image compression on optical coherence tomography (OCT) images in eyes with diabetic macular edema (DME). Methods Twenty eyes of 30 patients diagnosed with DME were included in this retrospective observational case series. Horizontal OCT scans centered at the center of the fovea were conducted using spectral-domain OCT (Spectral OCT/SLO®). The images were exported to Tag Image File Format (TIFF) and then transformed to 10, 5, and 1 quality of Joint Photographic Experts Group (JPEG) format using Photoshop. OCT images were taken before and after intravitreal bevacizumab injection. The presence of intraretinal fluid, foveolar ...

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    12. Optical Coherence Tomography to Evaluate Dengue

      Optical Coherence Tomography to Evaluate Dengue

      The recent report you published on the use of optical coherence tomography (OCT) to evaluate dengue was very interesting [ 1 ]. Rhee and Han [ 1 ] concluded that "Follow-up examination of individuals with dengue fever and associated visual impairment should involve the use of OCT to evaluate visual acuity and visual field change." In fact, the ocular complications of dengue are typically overlooked, as a proper examination is rarely performed. As Mendes et al. [ 2 ] noted, "Dengue fever can lead to visual impairment detectable by ophthalmological exams such as angiography, retinography, and OCT imaging, as well as retinal and cortical electrophysiology." Severe ...

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    13. Efficacy of Intravitreal Anti-vascular Endothelial Growth Factor or Steroid Injection in Diabetic Macular Edema According to Fluid Turbidity in Optical Coherence Tomography

      Efficacy of Intravitreal Anti-vascular Endothelial Growth Factor or Steroid Injection in Diabetic Macular Edema According to Fluid Turbidity in Optical Coherence Tomography

      Purpose To determine if short term effects of intravitreal anti-vascular endothelial growth factor or steroid injection are correlated with fluid turbidity, as detected by spectral domain optical coherence tomography (SD-OCT) in diabetic macular edema (DME) patients. Methods A total of 583 medical records were reviewed and 104 cases were enrolled. Sixty eyes received a single intravitreal bevacizumab injection (IVB) on the first attack of DME and 44 eyes received triamcinolone acetonide treatment (IVTA). Intraretinal fluid turbidity in DME patients was estimated with initialintravitreal SD-OCT and analyzed with color histograms from a Photoshop program. Central macular thickness and visual acuity using ...

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    14. Optical coherence tomographic observation of morphological features of neointimal tissue after drug-eluting stent implantation

      Optical coherence tomographic observation of morphological features of neointimal tissue after drug-eluting stent implantation

      Purpose The impacts of different time courses and the degree of neointimal growth on neointimal morphology have not yet been sufficiently investigated. Therefore, we evaluated the morphological features of neointimal tissue after drug-eluting stent (DES) implantation using optical coherence tomography (OCT). Materials and Methods The morphological features of neointimal tissue in stented segments with a maximal percentage of cross-sectional area (CSA) stenosis of neointima were evaluated in 507 DES-treated lesions with >100 µm mean neointimal thickness on follow-up OCT. Neointimal tissue was categorized as homogeneous, heterogeneous, layered, or neoatherosclerotic. Results In lesions with <50% of neointimal CSA stenosis, homogeneous neointima ...

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    15. Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Relationship between the Lamina Cribrosa, Outer Retina, and Choroidal Thickness as Assessed Using Spectral Domain Optical Coherence Tomography

      Purpose To evaluate the characteristics and relationship between peripapillary choroidal thickness (pCT), lamina cribrosa thickness (LCT), and peripapillary outer retinal layer thickness (pORT) as determined using spectral domain optical coherence tomography (SD-OCT) enhanced depth imaging (EDI). Methods In total, 255 participants were included (87 healthy subjects, 87 glaucoma suspects (GS), and 81 glaucoma cases). The pORT, defined as the thickness between the posterior outer plexiform layer and the retinal pigment epithelium (RPE) interface, and the pCT, between the outer margin of the RPE and the choroidal-scleral interface, were manually measured using EDI scanning of the circumpapillary retinal nerve fiber layer ...

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    16. Detection of early changes in caries lesion using QLF-D and OCT

      Detection of early changes in caries lesion using QLF-D and OCT

      Objectives We aimed to compare the differences in caries lesion changes when measured by QLF-D as fluorescence loss and by SS-OCT as lesion depth with respect to demineralized time, during formation of artificial early caries lesion. We also demonstrated that QLF-D and SS-OCT can be used effectively in monitoring the longitudinal progression of simulated caries lesions. Methods Ten bovine incisors were sectioned (5×4 mm) and embedded in epoxy resin. An acid-resistant nail varnish was applied to a part of the tooth surfaces to protect sound enamel (2×4 mm). To generate lesions, each specimen was immersed in 40 ml ...

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    17. Reproducibility of Peripapillary Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Pseudophakic Eyes

      Reproducibility of Peripapillary Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Pseudophakic Eyes

      Purpose To assess the reproducibility of circumpapillary retinal nerve fiber layer (cpRNFL) thickness measurement (measurement agreement) and its color-coded classification (classification agreement) by Cirrus spectral domain optical coherence tomography (OCT) in pseudophakic eyes. Methods Two-hundred five participants having glaucoma or glaucoma suspected eyes underwent two repeated Cirrus OCT scans to measure cpRNFL thickness (optic disc cube 200 × 200). After classifying participants into three different groups according to their lens status (clear media, cataract, and pseudophakic), values of intra-class coefficient (ICC), coefficient of variance, and test-retest variability were compared between groups for average retinal nerve fiber layer (RNFL) thicknesses and that ...

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    18. Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

      Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

      Abstract Purpose To evaluate the characteristics of choroidal nevus using the enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT), with a comparison to the B scan ultrasound (BUS) findings. Methods Medical records of 124 eyes of 124 choroidal nevus patients were reviewed retrospectively. All patients underwent fundus photography (FP), EDI SD-OCT, and BUS. Results Of 124 eyes with choroidal nevus examined by EDI SD-OCT, 43 eyes (35%) displayed good images to study. The most common EDI-OCT imaging features included choroidal shadowing, choriocapillary thinning, retinal pigment epithelial changes, and overlying subretinal fluid. The mean nevus thickness was 817 µm ...

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    19. Advanced Imaging Technologies for the Detection of Dysplasia and Early Cancer in Barrett Esophagus

      Advanced Imaging Technologies for the Detection of Dysplasia and Early Cancer in Barrett Esophagus

      Abstract Advanced esophageal adenocarcinomas arising from Barrett esophagus (BE) are tumors with an increasing incidence and poor prognosis. The aim of endoscopic surveillance of BE is to detect dysplasia, particularly high-grade dysplasia and intramucosal cancers that can subsequently be treated endoscopically before progression to invasive cancer with lymph node metastases. Current surveillance practice standards require the collection of random 4-quadrant biopsy specimens over every 1 to 2 cm of BE (Seattle protocol) to detect dysplasia with the assistance of white light endoscopy, in addition to performing targeted biopsies of recognizable lesions. This approach is labor-intensive but should currently be considered ...

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    20. Use of optical coherence tomography to evaluate visual acuity and visual field changes in dengue Fever

      Use of optical coherence tomography to evaluate visual acuity and visual field changes in dengue Fever

      Dengue fever is a viral disease that is transmitted by mosquitoes and affects humans. In rare cases, dengue fever can cause visual impairment, which usually occurs within 1 month after contracting dengue fever and ranges from mild blurring of vision to severe blindness. Visual impairment due to dengue fever can be detected through angiography, retinography, optical coherence tomography (OCT) imaging, electroretinography, event electroencephalography (visually evoked potentials), and visual field analysis. The purpose of this study is to report changes in the eye captured using fluorescein angiography, indocyanine green, and OCT in 3 cases of dengue fever visual impairment associated with ...

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    21. Comparison of Diagnostic Power Among OCT Parameters According to Peripapillary Atrophy in High Myopic Glaucoma

      Comparison of Diagnostic Power Among OCT Parameters According to Peripapillary Atrophy in High Myopic Glaucoma

      Purpose To evaluate diagnostic power to detect glaucoma in high myopic eyes with peripapillary atrophy among optical coherence tomography (OCT) parameters. Methods Fifty eyes of 31 glaucoma patients with myopia of -6.00 diopters or less and a peripapillary atrophy (PPA) were classified into a group with a PPA located beyond the circumpapillary OCT scan circle (group A) and a group with a PPA confined within the scan circle (group B). Circumpapillary retinal nerve fiber layer (cpRNFL), total macula (TM), and ganglion cell-inner plexiform layer (GCIPL) thickness were measured in each group and the diagnostic power of each measurement was ...

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    22. Comparison of Choroidal Thickness in Patients with Diabetes by Spectral-domain Optical Coherence Tomography

      Comparison of Choroidal Thickness in Patients with Diabetes by Spectral-domain Optical Coherence Tomography

      Purpose To evaluate choroidal thickness in diabetes patients using spectral-domain optical coherence tomography. Methods We examined 203 eyes of 203 diabetic participants and 48 eyes of 48 healthy controls. The choroidal thickness at the foveal lesion was measured by enhanced-depth imaging optical coherence tomography. The participants were grouped according to diabetic retinopathy grade: no diabetic change, mild-to-moderate or severe non-proliferative, or proliferative diabetic retinopathy. The study parameters included history, age, axial length, intraocular pressure, central retinal thickness, fasting glucose, and blood pressure. Results The subfoveal choroidal thickness was thinner in eyes with non-proliferative or proliferative diabetic retinopathy than in normal ...

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    23. Anti-VEGF-refractory Exudative Age-related Macular Degeneration: Differential Response According to Features on Optical Coherence Tomography

      Anti-VEGF-refractory Exudative Age-related Macular Degeneration: Differential Response According to Features on Optical Coherence Tomography

      Purpose To describe optical coherence tomography (OCT) characteristics of neovascular age-related macular degeneration (AMD) patients refractory to intravitreal anti-vascular endothelial growth factor (VEGF) injections (ranibizumab, bevacizumab) and their responses to alternative anti-VEGF agents or photodynamic therapy (PDT). Methods A retrospective review of 267 neovascular AMD patients treated with intravitreal anti-VEGF injections. Results Twenty patients (7.5%) were refractory to anti-VEGF injections (stationary or increased retinal exudation despite three or more monthly injections). They were grouped into either the extensive intraretinal fluid group (IRF group, 9 patients) or the subretinal fluid only group (SRF group, 11 patients) according to OCT findings ...

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    24. Analysis of Peripapillary Atrophy According to the Optic Disc Shape Using Spectral Domain OCT

      Analysis of Peripapillary Atrophy According to the Optic Disc Shape Using Spectral Domain OCT

      Purpose To analyze the structural changes in the β-zone of peripapillary atrophy (PPA-β) using cross-sectional image of the optic disc head from spectral-domain optical coherence tomography (SD-OCT) according to the optic disc shape. Methods One hundred thirty-seven eyes in 137 patients with glaucoma having PPA-β and 31 normal eyes (control group) were evaluated retrospectively. Cross-sectional images of the optic disc were taken using the Cirrus HD-OCT. We classified optic disc patterns into normal, focal, myopic, generalized enlargement and senile sclerotic appearance types and analyzed the shape of Bruch's membrane (BM), composition of retinal layer and retinal slope according to ...

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    73-96 of 114 « 1 2 3 4 5 »
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