1. 1-4 of 4
    1. Performance of the “Rule of 5” for Detecting Glaucoma Progression Between Visits with Optical Coherence Tomography

      Performance of the “Rule of 5” for Detecting Glaucoma Progression Between Visits with Optical Coherence Tomography

      Purpose To evaluate whether loss of 5 μm in global retinal nerve fiber layer (RNFL) thickness on spectral-domain optical coherence tomography (SDOCT) between two consecutive visits is specific for glaucoma progression. Design Prospective cohort. Participants 92 eyes in 49 controls and 300 eyes in 210 glaucoma subjects. Methods Study subjects completed at least five standard automated perimetry and SDOCT examinations at 6-month intervals over at least 2 years. Eyes were categorized as progressing from glaucoma if the average RNFL declined by 5 μm between two consecutive visits. The false positive proportion was estimated by two methods: 1) 5 μm loss ...

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    2. Comparative Intraoperative Anterior Segment Optical Coherence Tomography Findings in Pediatric Patients with and without Glaucoma

      Comparative Intraoperative Anterior Segment Optical Coherence Tomography Findings in Pediatric Patients with and without Glaucoma

      Purpose To compare the angle structures intraoperatively using anterior segment optical coherence tomography (AS OCT) in children with and without glaucoma. Design Prospective comparative study, with single masked grader evaluating AS OCT images. Participants This study included a total of 44 eyes of 8 children with glaucoma and 14 children without glaucoma undergoing ophthalmic surgery under general anesthesia. The median age for the glaucoma group was 6 months (range 0.5-108 months), and for the non-glaucoma group was 42 months (range 14-95 months). Methods An Envisu C2300 handheld OCT with a high resolution anterior segment lens was used to capture ...

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    3. En face optical coherence tomography imaging of beta and gamma parapapillary atrophy in high myopia

      En face optical coherence tomography imaging of beta and gamma parapapillary atrophy in high myopia

      Objective Recent studies have suggested that optical coherence tomography (OCT)-based classification of parapapillary atrophy (PPA) may be helpful in distinguishing glaucomatous from myopic optic disc changes. However, the pathological implications of PPA may be different in highly myopic eyes that exhibit optic disc deformations distinct from low to moderate myopia. Therefore, we conducted the current study to investigate factors associated with OCT-defined PPA zones measured in en face reconstructed swept source OCT (SS OCT) images in highly myopic eyes. Design Retrospective, cross-sectional study. Participants Seventy-seven eyes of 55 subjects with high myopia (spherical equivalent refractive error ≤ -8 diopters or ...

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    4. Gray Optic Disc Crescent: Evaluation of Anatomical Correlate by Spectral Domain Optical Coherence Tomography

      Gray Optic Disc Crescent: Evaluation of Anatomical Correlate by Spectral Domain Optical Coherence Tomography

      Purpose To test the hypothesis that the anatomical correlate of the gray optic disc crescent is pigmentation of externally oblique border tissue of Elschnig. Design Observational cross-sectional study. Participants African American adult males with or without clinically apparent gray optic disc crescents. Methods McNemar’s test for paired data and kappa statistic with 95% confidence intervals were used to examine the relationships between eyes with or without gray optic disc crescents and corresponding spectral domain-optical coherence tomography (SD-OCT) images with Enhanced Depth Imaging (EDI). Main Outcome Measures Correlation between clinical gray optic disc crescents and hyperreflectivity of externally oblique border ...

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    1-4 of 4
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