1. Articles from e-ceo.org

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    1. Future Directions of Optical Coherence Tomography in Otology: A Morphological and Functional Approach

      Future Directions of Optical Coherence Tomography in Otology: A Morphological and Functional Approach

      Optical coherence tomography (OCT) is a real-time optical imaging modality that enables tomographic imaging at the submicron scale. Basic research into applications of OCT systems in the field of otology has been conducted. For instance, Oh et al. [1] recently reported that OCT provided noninvasive, nondestructive two-dimensional cross-sectional and three-dimensional volumetric images of middle-ear and inner ear structures in rodents. Anatomical depth-resolved imaging has shown promising potential for morphological measurements of the middle and inner ear in chinchillas [2] and mice with blast trauma [3]. Moreover, OCT has demonstrated its capability as a functional analytical tool by characterizing the vibration ...

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    2. Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography

      Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography

      Objectives. This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic technology in ear imaging. Method. Five rats and mice were included, and the swept-source OCT system was applied to confirm the extent of visibility of the middle and inner ear and measure the length or thickness of the microstructures in the ear. The cochlea was subsequently dissected following OCT and histologically evaluated to compare with the OCT images. Results. The middle ear microstructures such as ...

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    3. In Vivo Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study

      In Vivo Vibration Measurement of Middle Ear Structure Using Doppler Optical Coherence Tomography: Preliminary Study

      Objectives Doppler optical coherence tomography (DOCT) is useful for both, the spatially resolved measurement of the tympanic membrane (TM) oscillation and high-resolution imaging. We demonstrated a new technique capable of providing real-time two-dimensional Doppler OCT image of rapidly oscillatory latex mini-drum and in vivo rat TM and ossicles. Methods Using DOCT system, the oscillation of sample was measured at frequency range of 1–4 kHz at an output of 15 W. After the sensitivity of the DOCT system was verified using a latex mini-drum consisting of a 100 μm-thick latex membrane, changes in displacement of the umbo and contacted area ...

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    1-3 of 3
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