1. Articles from Healio.com

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    1. Optos launches Monaco, UWF retinal imaging device with OCT

      Optos launches Monaco, UWF retinal imaging device with OCT

      Optos plc, part of Nikon Corp., announced the U.S. launch of Monaco, the first ultra-widefield imaging device combined with optical coherence tomography. Monaco is a compact desktop UWF retinal imaging device , which provides greater imaging functionality, according to a company press release. “The addition of OCT to our ultra-widefield imaging device offers a more comprehensive array of imaging tools in one machine, enabling eye care practitioners to see and treat retinal pathology earlier and more effectively,” Robert Kennedy, CEO of Optos, said in the release. The device is the company’s first combined imaging device with ultra-widefield color imaging ...

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      Mentions: Optos
    2. Optical Coherence Tomography Angiography and Ultra-Widefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti

      Optical Coherence Tomography Angiography and Ultra-Widefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti

      Incontinentia pigmenti (IP) is a rare X-linked dominant disorder that can cause retinal nonperfusion, neovascularization, and retinal detachment. Evaluation of the peripheral retinal vasculature and appropriate treatment can reduce the risk of blindness. The authors report the use of a handheld prototype optical coherence tomography angiography (OCTA) and ultra-widefield OCT (UWF-OCT) during exam under anesthesia of a 2-year-old with a history of severe early onset IP. UWF-OCT and OCTA may be used as noninvasive imaging modalities for IP and similar retinal vascular disorders in supine young children.

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    3. Choroidal Caverns: A Previously Unreported Optical Coherence Tomography Finding in Best Vitelliform Dystrophy

      Choroidal Caverns: A Previously Unreported Optical Coherence Tomography Finding in Best Vitelliform Dystrophy

      Best vitelliform macular dystrophy (VMD) is an autosomal dominant inherited dystrophy, most frequently caused by mutations in the BEST1 gene. The authors describe “choroidal caverns,” a previously unreported optical coherence tomography finding in the choriocapillary and choroid of Best VMD. Histopathologic examination in eyes with Best VDM shows extensive deposition of lipofuscin in the retinal pigment epithelium (RPE) throughout the retina and accumulation of fibrillar material under the RPE and in the choroid. This supports the hypothesis that choroidal caverns could be a sign of the degenerative process involving the choroid in eyes with Best VMD.

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    4. Study: Inexperienced operators effectively perform SD-OCT imaging

      Study: Inexperienced operators effectively perform SD-OCT imaging

      OCT imaging may be appropriate for nonprofessional photographers to administer to undilated patients and in quantitative parameters for adequate screening in a community setting, according to researchers. Researchers reported that patients with open angle glaucoma underwent OCT imaging with the Cirrus SD-OCT (Carl Zeiss Meditec Inc.) as part of their routine care on that day. A clinical examination by a glaucoma specialist was also performed to rule out other conditions that could affect the optic disc or retinal nerve fiber layer (RNFL) and to confirm that the observed disc changes and field deficits were due to glaucoma, according to researchers ...

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    5. Choroidal Vascularity Index in Retinitis Pigmentosa: An OCT Study

      Choroidal Vascularity Index in Retinitis Pigmentosa: An OCT Study

      BACKGROUND AND OBJECTIVE: To evaluate structural changes in the choroid of patients with retinitis pigmentosa (RP) using swept-source optical coherence tomography (OCT) scans. PATIENTS AND METHODS: A prospective study was conducted comparing 35 eyes of 35 patients with RP and 26 eyes of 26 normal patients. OCT images of the choroid were binarized into luminal and stromal areas to derive choroidal vascularity index (CVI). Subfoveal choroidal thickness (CT) was also measured and compared. RESULTS: There was a significant decrease in the mean CVI among eyes with RP as compared to normal eyes (56.91 ± 1.43% vs. 59.47 ± 1 ...

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    6. Swept-Source OCT Angiographic Imaging of a Central Retinal Vein Occlusion During Pregnancy

      Swept-Source OCT Angiographic Imaging of a Central Retinal Vein Occlusion During Pregnancy

      To avoid fluorescein angiography in a pregnant woman diagnosed with a central retinal vein occlusion (CRVO), swept-source optical coherence tomography angiography (SS-OCTA) was performed and showed no evidence of decreased central retinal perfusion leading to the diagnosis of a nonischemic CRVO. Five months after an intravitreal injection of steroid, both her vision and the retinal appearance had returned to normal. This case demonstrates how a noninvasive, safe, 12 mm × 12 mm SS-OCTA image of a CRVO is useful in evaluating the retinal perfusion at presentation and follow-up during pregnancy.

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    7. Retinal Arteriovenous Malformation Assessment Using Swept-Source OCT Angiography

      Retinal Arteriovenous Malformation Assessment Using Swept-Source OCT Angiography

      Swept-source optical coherence tomography angiography (SS-OCTA) is a promising new imaging modality for assessing retinal and choroidal vasculature. Faster scanning speed, large number of A-scan acquisition, and enhanced depth penetration has enhanced the detailed analysis of retinal layers. The authors discuss SS-OCTA features of a rare case of retinal arteriovenous malformation. Image analysis revealed the anomalous large-caliber vessels occupying up to the entire retinal thickness with associated echolucent changes in the inner retinal layers surrounding the retinal vessels, along with disruption of the outer retinal layers, including the inner/outer segments of photoreceptors beneath the large tortuous vessels outside the ...

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    8. Evaluation of Choroidal Hemangioma and Treatment With Photodynamic Therapy by Using Enhanced Depth Imaging Optical Coherence Tomography

      Evaluation of Choroidal Hemangioma and Treatment With Photodynamic Therapy by Using Enhanced Depth Imaging Optical Coherence Tomography

      BACKGROUND AND OBJECTIVE: To evaluate enhanced depth imaging optical coherence tomography (EDI-OCT) features of choroidal hemangioma and changes following photodynamic therapy (PDT). PATIENTS AND METHODS: Retrospective review of 21 choroidal hemangiomas. RESULTS: On EDI-OCT, choroidal hemangioma showed low internal reflectivity in 47% of lesions and high internal reflectivity in 53%. The most common associated features were normal-looking honeycomb-like pattern in choriocapillaris in all lesions, inner segment/outer segment abnormality in 62%, photoreceptor outer segment abnormality in 62%, subretinal fluid with speckles in 62%, and shaggy photoreceptors in 57% of lesions. Internal reflectivity changed from low to high in 67% of ...

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    9. Presumed Solitary Circumscribed Retinal Astrocytic Proliferation in the Fovea With OCT Angiography: A Misnomer

      Presumed Solitary Circumscribed Retinal Astrocytic Proliferation in the Fovea With OCT Angiography: A Misnomer

      The retinal lesion known as the presumed solitary circumscribed retinal astrocytic proliferation (pSCRAP) is a benign retinal tumor. Although many of the clinical characteristics of the lesion have been described, much about the pathogenesis of this uncommon tumor is not yet known. Here, the authors report a pSCRAP lesion in the fovea with secondary vision loss occurring in middle age. Structural optical coherence tomography (OCT) scans indicate that the lesion arises from the deep retina or retinal pigment epithelium (RPE), whereas OCT angiography characteristics of the lesion show a lack of intrinsic or paralesional vascular flow, indicating that this lesion ...

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    10. High-Definition Optical Coherence Tomography of the Macula in Deprivational Amblyopia

      High-Definition Optical Coherence Tomography of the Macula in Deprivational Amblyopia

      High-Definition Optical Coherence Tomography of the Macula in Deprivational Amblyopia Christiane Al-Haddad, MD; Carl-Joe Mehanna, MD; Karine Ismail, MSc Ophthalmic Surgery, Lasers and Imaging Retina. 2018;49(3):198-204 This study evaluated macular thickness in deprivational amblyopia and compared it to matched controls. PATIENTS AND METHODS: The authors present a cross-sectional study of patients with amblyopia from pediatric cataract and matched controls.

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    11. Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging

      Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging

      BACKGROUND AND OBJECTIVE: To demonstrate the feasibility of retinal and anterior segment intraoperative widefield imaging using an ultrahigh-speed, swept-source optical coherence tomography (SS-OCT) surgical microscope attachment. PATIENTS AND METHODS: A prototype post-objective SS-OCT using a 1,050-nm wavelength, 400 kHz A-scan rate, vertical cavity surface-emitting laser (VCSEL) light source was integrated to a commercial ophthalmic surgical microscope after the objective. Each widefield OCT data set was acquired in 3 seconds (1,000 × 1,000 A-scans, 12 × 12 mm 2 for retina and 10 × 10 mm 2 for anterior segment). RESULTS: Intraoperative SS-OCT was performed in 20 eyes of 20 patients ...

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    12. DISCOVER study shows feasibility, usefulness of intraoperative OCT

      DISCOVER study shows feasibility, usefulness of intraoperative OCT

      According to 3-year results of the DISCOVER study, microscope-integrated intraoperative OCT during ophthalmic surgery is feasible and useful as it relates to surgical decision-making. The large-scale study enrolled 837 eyes, of which 244 eyes were enrolled in the anterior segment arm and 593 eyes were enrolled in the posterior segment arm. In 216 patients in the anterior segment arm, intraoperative OCT provided valuable feedback, most frequently when evaluating the graft-host apposition and when assessing the extent of interface fluid in Descemet’s stripping automated endothelial keratoplasty and Descemet’s membrane endothelial keratoplasty. In 106 patients, the information resulted in changes ...

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      Mentions: Bioptigen Leica
    13. Use of Optical Coherence Tomography Angiography in Masqueraders of Wet Age-Related Macular Degeneration and Choroidal Neovascularization

      Use of Optical Coherence Tomography Angiography in Masqueraders of Wet Age-Related Macular Degeneration and Choroidal Neovascularization

      The role of optical coherence tomography angiography (OCTA) in the evaluation of the retinal and choroidal vasculature is much better understood today compared to its introduction in our clinics several years ago. Since 2015, we have seen numerous papers published comparing OCTA to conventional fluorescein angiography to evaluate various retinal disease states. Retina specialists are finally starting to process this flood of data. I asked Dimitra Skondra, MD, PhD, Sidney Schechet, MD, and Asadolah Movahedan, MD, to provide us with an overview of how OCTA can help us in the clinical setting to evaluate various choroidal diseases. Their approach to ...

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    14. Optical Coherence Tomography Angiography of the Macula in Adults With a History of Preterm Birth

      Optical Coherence Tomography Angiography of the Macula in Adults With a History of Preterm Birth

      BACKGROUND AND OBJECTIVE: To evaluate the fovea microvasculature in adult subjects with history of preterm birth using optical coherence angiography (OCTA). PATIENTS AND METHODS: In this retrospective study, macular OCTA images were obtained from adult subjects with a history of preterm birth. The presence of the foveal avascular zone (FAZ) and its size was determined. RESULTS: Ten eyes from six subjects with ages ranging from 26 years old to 65 years old were evaluated. A distinct FAZ was not observed in three eyes (30%). The FAZ was small in other eyes, ranging from 0.07 mm 2 to 0.18 ...

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    15. Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 × 9 mm 2 . The en face maximum projection was used to generate 2-D angiograms of different layers with color-coded images. Variable levels of perfusion within the lesion were identified, which correlate well ...

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    16. Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography

      Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography

      A patient previously diagnosed with Alport Syndrome was evaluated using multimodal imaging. Optical coherence tomography (OCT) demonstrated significant thinning of the inner retina within the macula, and inner retinal cysts were found in the peripheral macula. OCT angiography demonstrated loss of the choriocapillaris. Abnormal collagen appears to have multiple deleterious effects on the retinal and choroidal structure and vasculature.

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    17. Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment

      Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment

      A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy.

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    18. Optical Coherence Tomography in Children With Microtropia

      Optical Coherence Tomography in Children With Microtropia

      PURPOSE: To assess whether optical coherence tomography (OCT) could be useful for detecting and documenting fixation in patients with microtropia. METHODS: Retinal fixation observation was performed using spectral-domain OCT on amblyopic children with microtropia. The position between the retinal fixation point and the anatomical fovea was measured, in microns, using the system software tools. Only patients with a high level of cooperation, OCT scan quality signal of 7 or better, and visual acuity of 0.70 logarithm of the minimum angle of resolution (logMAR) or worse in the amblyopic eye were included. RESULTS: A total of 25 patients were included ...

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    19. Evaluation of Femtosecond Laser Versus Manual Clear Corneal Incisions in Cataract Surgery Using Spectral-Domain Optical Coherence Tomography

      Evaluation of Femtosecond Laser Versus Manual Clear Corneal Incisions in Cataract Surgery Using Spectral-Domain Optical Coherence Tomography

      PURPOSE: To investigate the wound healing changes of clear corneal incisions performed with a femtosecond laser or a steel bevel knife in cataract surgery using spectral-domain optical coherence tomography. METHODS: Prospectively, consecutive patients undergoing either femtosecond laser–assisted cataract surgery (femtosecond laser group) using the LenSx laser (Alcon Laboratories, Inc., Fort Worth, TX) or traditional cataract surgery using steel blades (control group) were enrolled. The incidence of posterior wound gape, Descemet's membrane detachment, posterior wound retraction, and the inner and outer corneal incision thicknesses were assessed. RESULTS: Compared to the control group, the femtosecond laser group had significantly lower ...

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    20. A New OCT Finding in Purtscher-Like Retinopathy

      A New OCT Finding in Purtscher-Like Retinopathy

      The authors report a new spectral-domain optical coherence tomography (SD-OCT) appearance observed in two patients with Purtscher-like retinopathy. In this prospective case series of three eyes of two patients with Purtscher-like retinopathy, the patients were assessed with biomicroscopy, fluorescein angiography (FA), and SD-OCT. The last examinations of the patients were performed at 3 months and 12 months, respectively. Both patients presented with decreased visual acuity. Fundus examination revealed a whitish-appearing parafoveal retina and scattered cotton-wool spots in the posterior retina. FA showed hypofluorescent spots that correspond to the cotton-wool spots and retinal hemorrhages seen clinically. SD-OCT scan of cotton-wool spots ...

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    21. Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography

      Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography

      A rare case of a woman in her thirties with double optic disc pits involving opposing sectors is reported. Significantly decreased vision due to macular schisis was noted. Wide-field optical coherence tomography revealed distinct laminar defects and glial tufts associated with each pit. This case illustrates a rare view into the pathogenesis of optic disc pits.

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    22. Multimodal Imaging Including Optical Coherence Tomography Angiography of a Patient With Argus II Retinal Prosthesis One Year After Implantation

      Multimodal Imaging Including Optical Coherence Tomography Angiography of a Patient With Argus II Retinal Prosthesis One Year After Implantation

      A 58-year-old man with end-stage retinitis pigmentosa (RP) and visual acuity of light perception in both eyes received simultaneous phacoemulsification with intraocular lens implantation and implantation of the Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA) to his right eye 1 year ago. He accomplished the fitting and rehabilitation sessions, and no extraocular or intraocular complications were encountered perioperatively, postoperatively, or during the follow-up. The patient used the prosthesis actively for 2.5 to 3 hours per day. In this report, the authors compare the multimodal imaging findings including optical coherence tomography angiography of the chronic electrically ...

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    1-24 of 281 1 2 3 4 ... 10 11 12 »
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