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    1. Swept-Source Optical Coherence Tomography Angiography Findings in Torpedo Maculopathy

      Swept-Source Optical Coherence Tomography Angiography Findings in Torpedo Maculopathy

      Torpedo maculopathy is a rare congenital anomaly of the retinal pigment epithelium (RPE). Various imaging modalities have been used to assess cases of torpedo maculopathy, including optical coherence tomography (OCT) and fundus autofluorescence (FAF). OCT angiography (OCTA) offers combined structural and flow characteristics of imaged lesions. The authors present OCTA findings in two cases of torpedo maculopathy. Common features include loss of RPE and choriocapillaris allowing greater visualization of larger vessels in the outer choroid. This confirms the potential of OCTA to provide greater detail of retinal and choroidal architecture and elucidate the histopathology of retino-choridal lesions.

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    2. OCT screening in internal medicine increases disease detection

      OCT screening in internal medicine increases disease detection

      It is no surprise that patients without a significant refractive error may wait until their 50s or even 60s before obtaining a comprehensive eye exam. Presbyopia in an emmetrope in some cases is a curse because it can be treated with store-bought reading glasses for decades. Jerome Sherman Some of the top glaucoma specialists in both optometry and ophthalmology now recommend optical coherence tomography screenings on everyone beginning at age 40. Glaucoma specialist George Cioffi, MD, chairman of the department of ophthalmology at Columbia University in New York, stated at the SUNY Glaucoma Symposium earlier this year that he supports ...

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    3. DualTrack Technology Improves Optical Coherence Tomography Angiography Image Quality

      DualTrack Technology Improves Optical Coherence Tomography Angiography Image Quality

      BACKGROUND AND OBJECTIVE: To evaluate the effects of DualTrack Motion Correction Technology on the performance of AngioVue optical coherence tomography angiography (Optovue, Freemont, CA). PATIENTS AND METHODS: Fifty subjects underwent two consecutive examinations with AngioVue. The operator inactivated the eye-tracking (ET) technology before the second examination. Two operators measured execution time, excluded low-quality images, and counted the number of motion artifacts per image. RESULTS: The mean execution time was lower without ET in all the groups ( P < .05), regardless of retinal diseases. Percentages of available images and low-quality images were 75.0% and 25.0%, respectively, with ET and 63 ...

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    4. Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis

      Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis

      BACKGROUND AND OBJECTIVE: To describe spectral-domain optical coherence tomography (SD-OCT) findings in eyes with endogenous fungal chorioretinitis and endophthalmitis. PATIENTS AND METHODS: Retrospective, observational case series of subjects at Wills Eye Hospital and William Beaumont Hospital were identified by screening OCT billing data and cross-referencing with patient charts. Clinical and imaging data were collected for each patient and reviewed. RESULTS: Twelve eyes of seven consecutive patients were identified, demonstrating two patterns of posterior ocular involvement: chorioretinal infiltration and superficial retinal/retinal vascular infiltration without choroidal involvement. Six of 12 eyes had follow-up imaging performed after antifungal treatment, which demonstrated decreased ...

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    5. Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography

      Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVES: To compare choriocapillaris perfusion of the fovea between patients with idiopathic epiretinal membrane (iERM) and normal controls and determine whether surgery affects it. PATIENTS AND METHODS: Both eyes of 45 patients with iERM and 28 healthy subjects were scanned by optical coherence tomography angiography (OCTA) preoperatively, and 25 of the patients were scanned postoperatively. Central parameters measured included flow area and parafovea vessel density of the foveal choriocapillaris. RESULTS: Both parameters were significantly lower in eyes with iERM (both P < .001) compared with both the unaffected fellow eyes and the normal control eyes (both P < .001) preoperatively ...

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    6. Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      PURPOSE: To report successful lenticule extraction using intraoperative optical coherence tomography (OCT) in a case of cap–lenticule adhesion during small incision lenticule extraction (SMILE). METHODS: Case report. RESULTS: A 22-year-old patient with a refractive error of −5.00 −0.50 × 120° and −5.00 −0.75 × 60° in the right and left eyes, respectively, was scheduled for SMILE. The lenticule was created using the VisuMax femtosecond laser system (Carl Zeiss Meditec, Jena, Germany). The surgeon experienced difficulty while extracting the lenticule in the right eye. The patient was immediately shifted under the surgical microscope integrated with intraoperative OCT. The ...

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    7. Noninvasive, High-Resolution Functional Macular Imaging in Subjects With Retinal Vein Occlusion

      Noninvasive, High-Resolution Functional Macular Imaging in Subjects With Retinal Vein Occlusion

      BACKGROUND AND OBJECTIVES: Several imaging modalities have been developed to characterize ischemia inherent in retinal vascular diseases. This study aims to predict the impact and to better establish the mechanisms of visual deterioration. A high-resolution functional imaging device is used, yielding quantitative data for macular blood flow and capillary network features in healthy eyes and in eyes with central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO). PATIENTS AND METHODS: This prospective, cross-sectional, comparative case series measured blood flow velocities (BFVs) and noninvasive capillary perfusion maps (nCPMs) in macular vessels in patients with BRVO/CRVO and in healthy ...

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    8. Optical Coherence Tomography Angiography Findings in Punctate Inner Choroidopathy

      Optical Coherence Tomography Angiography Findings in Punctate Inner Choroidopathy

      BACKGROUND AND OBJECTIVE: Punctate inner choroidopathy (PIC) is an inflammatory chorioretinopathy characterized by multiple punctate, hypopigmented fundus lesions. Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables high-resolution visualization of the retinal and choroidal vasculature. The objective of this study is to examine the OCTA findings in PIC. PATIENTS AND METHODS: Observational, retrospective review of five patients with PIC. RESULTS: OCTA revealed several features in PIC lesions: distinctly visible choroidal neovascular membranes when present, as well as flow voids within the choroid and choriocapillaris layers that correspond with hypocyanescent lesions on indocyanine green angiography. CONCLUSION: OCTA may ...

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    9. Presenter: Always image both eyes with OCT

      Presenter: Always image both eyes with OCT

      Eye care providers may have the opportunity to identify neurodegenerative diseases earlier through the use of high-resolution optical coherence tomography, according to Robert Sergott, MD, of Wills Eye Hospital. Sergott participated in the American Academy of Optometry’s plenary session, which was co-sponsored by Primary Care Optometry News. “In Alzheimer’s disease, 99% of clinical trials fail because there’s nothing left to treat. It’s diagnosed too late,” Sergott said. “This is the case for high-resolution OCT in your practice. It gives you objective vs. subjective data.” Sergott presented a number of case reports to illustrate his “rules” for ...

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    10. Accuracy of a New Swept-Source Optical Coherence Tomography Biometer for IOL Power Calculation and Comparison to IOLMaster

      Accuracy of a New Swept-Source Optical Coherence Tomography Biometer for IOL Power Calculation and Comparison to IOLMaster

      PURPOSE: To investigate the accuracy of the measurements provided by a new optical biometer (OA-2000, Tomey Corporation, Nagoya, Japan) for calculating the intraocular lens (IOL) power and to compare the refractive outcomes to those obtained with the IOLMaster 500 (Carl Zeiss Meditec, Jena, Germany). METHODS: In this interventional multicenter study, consecutive patients having cataract surgery were enrolled. Only the IOL model used in the largest sample of patients was selected and the eyes implanted with that IOL were subsequently analyzed. The OA-2000, an optical biometer based on swept-source optical coherence tomography (SS-OCT), was used to measure axial length and corneal ...

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    11. Optovue adds angiography to AngioVue Essential

      Optovue adds angiography to AngioVue Essential

      Optovue debuted its optical coherence tomography angiography capability for the AngioVue Essential at Vision Expo West . The AngioVue Essential offers high-resolution, noninvasive imaging of retinal vasculature to help clinicians visualize ocular disease, the company said in a press release. The new OCT-A feature offers a single-page report that displays OCT B-scans and individual layers of retinal vasculature. The system offers the addition of ocular health screening to a basic eye exam. Optovue also announced that its iWellness scan will be added to the Avanti System, an OCT imaging platform. Dubbed Avanti Wellness, the combination allows optometrists to identify the signs ...

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      Mentions: Optovue
    12. Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      Multi-Modal Imaging Including Optical Coherence Tomography Angiography in Patients With Posterior Multifocal Placoid Pigment Epitheliopathy

      ACKGROUND AND OBJECTIVE: New imaging methods provide novel insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Four patients (eight eyes) in acute, subacute, and late phases of the disease were analyzed with multi-modal imaging methods including optical coherence tomography angiography (OCTA), structural OCT, fundus photography, and fundus autofluorescence. One patient was observed during the entire disease course. RESULTS: In acute and subacute phases of the disease, an early blockage in fluorescein angiography was found. OCTA showed perfusion defects in choriocapillaris and choroid slabs. During the course of disease, perfusion deficits observed in OCTA ...

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    13. Quantitative and Qualitative Features of Spectral-Domain Optical Coherence Tomography Provide Prognostic Indicators for Visual Acuity in Patients With Choroideremia

      Quantitative and Qualitative Features of Spectral-Domain Optical Coherence Tomography Provide Prognostic Indicators for Visual Acuity in Patients With Choroideremia

      BACKGROUND AND OBJECTIVE: To identify qualitative and quantitative features of spectral-domain optical coherence tomography (SD-OCT) as prognostic indicators of visual acuity (VA) loss in patients with choroideremia (CHM). . PATIENTS AND METHODS: Retrospective study of 57 male patients with CHM. Central foveal thickness (CFT), subfoveal choroidal thickness (SCT), fundus autofluorescence area, and evidence of outer retinal and choroidal degeneration were analyzed by SD-OCT. RESULTS: Best-corrected VA logMAR at baseline was associated with CFT at baseline (r = −0.47; P < .01), CFT at most recent follow-up (r = −0.27; P < .01), and SCT at baseline (r = −0.31; P < .01). Ellipsoid zone ...

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    14. En Face Optical Coherence Tomography Angiography Imaging Versus Fundus Photography in the Measurement of Choroidal Nevi

      En Face Optical Coherence Tomography Angiography Imaging Versus Fundus Photography in the Measurement of Choroidal Nevi

      BACKGROUND AND OBJECTIVES: Choroidal nevi are common benign intraocular tumors with a small risk of malignant transformation. This retrospective study investigates the use of en face spectral-domain optical coherence tomography angiography (SD-OCTA) in determining the clinical features and measurement of choroidal nevi. PATIENTS AND METHODS: Patients with choroidal nevi were imaged with both OCTA and a fundus photography device. Greatest longitudinal dimension (GLD), perpendicular dimension (PD), and the GLD/PD ratio were assessed on each device. Inter-device variation and intra- and inter-rater reliability analyses were performed. RESULTS: Fourteen patients with choroidal nevi were included. No significant difference between the GLD ...

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    15. Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma

      Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma

      etinal cavernous hemangioma is a rare, benign, retinal tumor characterized by angiomatous proliferation of vessels within the inner retina or the optic disc.1 Here we report a case of retinal cavernous hemangioma on the margin of the optic disc in the right eye of a 61-year-old asymptomatic female. The lesion was studied with multimodal imaging which included structural optical coherence tomography, fluorescein angiography, blue fundus auto-fluorescence, optical coherence tomography angiography (OCTA) (DRI OCT Triton; Topcon, Tokyo, Japan) and visual field examination. Blood circulation inside retinal cavernous hemangioma lesion is typically low-stagnant.2 However, OCTA demonstrated blood flow inside the ...

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    16. Torpedo Maculopathy in a 6-Month-Old Infant: Early Clinical and Optical Coherence Tomography Findings

      Torpedo Maculopathy in a 6-Month-Old Infant: Early Clinical and Optical Coherence Tomography Findings

      A 6-month-old male infant presented for routine ophthalmologic examination. Indirect ophthalmoscopy revealed a flat, oval, hypopigmented lesion located in the temporal macula in the right eye with the tip pointing toward the fovea, which was compatible with torpedo maculopathy. Optical coherence tomography (OCT) was performed at the time of diagnosis. OCT scans of the lesion revealed slight retinal pigment epithelium hyperreflectivity. This case serves as the earliest OCT finding of the youngest patient diagnosed as having torpedo maculopathy in the literature.

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    17. Quantitative Features of the Choriocapillaris in Healthy Individuals Using Swept-Source Optical Coherence Tomography Angiography

      Quantitative Features of the Choriocapillaris in Healthy Individuals Using Swept-Source Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To quantify vessel density (VD) and grey value (GV) as a measure of flow in the choriocapillaris (CC) in healthy subjects with optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: In this prospective, noncomparative case series, 3 mm × 3 mm OCTA images of 36 eyes of 22 healthy individuals were obtained using a swept-source instrument. VD and GV levels were calculated on CC en face slabs in the central 1-mm (subfoveal field) and surrounding 2.5-mm parafoveal ring. VD was calculated as a ratio of vessel area over nonvessel area following image binarization. GV was computed as ...

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    18. Evaluation of Macular Perfusion in Healthy Smokers by Using Optical Coherence Tomography Angiography

      Evaluation of Macular Perfusion in Healthy Smokers by Using Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To investigate the macular perfusion changes in healthy smokers by using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: OCTA measurements were taken for the right eyes of 40 smokers (Group 1) and age- and sex-matched control cases (Group 2). Group 1 underwent OCTA scanning with the XR Avanti AngioVue OCTA (Optovue, Fremont, CA) at baseline and at 5 minutes, 30 minutes, and 60 minutes after one standard cigarette smoking. The same scanning protocol was applied without smoking in Group 2. Macular vessel area density, flow index of the choriocapillaris, foveal avascular zone (FAZ), and central macular ...

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      Mentions: Optovue
    19. Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis

      Swept-Source Optical Coherence Tomography Angiography in West Nile Virus Chorioretinitis and Associated Occlusive Retinal Vasculitis

      A 65-year-old man with diabetes and a history of fever of unknown origin 2 weeks earlier complained of sudden decreased vision in the left eye. The patient was diagnosed with bilateral West Nile virus (WNV) chorioretinitis associated with occlusive retinal vasculitis in the left eye. Swept-source optical coherence tomography angiography (SS-OCTA) of the left eye showed extensive, well-delineated, hypointense non-perfusion areas and perifoveal capillary arcade disruption in the superficial capillary plexus, as well as larger non-perfusion areas, capillary rarefaction, and diffuse capillary network attenuation and disorganization in the deep capillary plexus. OCTA may be a valuable tool for noninvasively assessing ...

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    20. Distinguishing White Dot Syndromes With Patterns of Choroidal Hypoperfusion on Optical Coherence Tomography Angiography

      Distinguishing White Dot Syndromes With Patterns of Choroidal Hypoperfusion on Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVE: To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected. This study was approved by the institutional review board at Massachusetts Eye and Ear. RESULTS: Unique patterns of choroidal ...

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      Mentions: Optovue
    21. Advances in glaucoma management blur the barriers between subspecialties

      Advances in glaucoma management blur the barriers between subspecialties

      Glaucoma management has undergone significant advancements in recent years. New minimally invasive surgical options have become available, filling in the gap between medical management and major surgeries such as trabeculectomy and tubes. On the diagnostic side, OCT technology has allowed a better understanding of the pathophysiology of glaucoma and more accurate monitoring of the effects of treatment, and has broadened the view to new imaging markers for progression. Glaucoma has opened up as a subspecialty to share areas of interest with other subspecialties and even other branches of medicine. “The life of a glaucoma specialist has become a lot busier ...

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    22. Real-time imaging adds interactive dimension to vitreoretinal surgery, training

      Real-time imaging adds interactive dimension to vitreoretinal surgery, training

      First introduced in the early 1990s, OCT is a noninvasive imaging technique that obtains high-resolution, cross-sectional images of the retina and other ophthalmic tissues. In recent years, this technology has transitioned from being only available in the clinic to being able to be utilized in the operating room. Intraoperative OCT has allowed ophthalmologists to access real-time imaging of vitreoretinal surgery for the first time, adding a new dimension to surgery and education, according to a 2016 study published in Eye (London) by Justis P. Ehlers, MD. There are several FDA-approved systems with optional add-ons to improve performance. Companies such as ...

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    23. Diagnosing Choroidal Neovascularization in Asymptomatic Individuals Using Optical Coherence Tomography Angiography

      Diagnosing Choroidal Neovascularization in Asymptomatic Individuals Using Optical Coherence Tomography Angiography

      Optical coherence tomography angiography (OCTA) is a noninvasive, rapid imaging technique that generates angiographic images without intravenous dye injections. Cross-sectional studies have described the presence of asymptomatic choroidal neovascularization (CNV) in patients with intermediate age-related macular degeneration (AMD). This case report describes the OCT features on longitudinal follow-up of a patient who started with unilateral asymptomatic CNV and eventually developed symptomatic exudative AMD.

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    1-24 of 254 1 2 3 4 ... 9 10 11 »
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