1. Articles from Healio.com

    healio.com

  2. 1-24 of 268 1 2 3 4 ... 10 11 12 »
    1. Use of Optical Coherence Tomography Angiography in Masqueraders of Wet Age-Related Macular Degeneration and Choroidal Neovascularization

      Use of Optical Coherence Tomography Angiography in Masqueraders of Wet Age-Related Macular Degeneration and Choroidal Neovascularization

      The role of optical coherence tomography angiography (OCTA) in the evaluation of the retinal and choroidal vasculature is much better understood today compared to its introduction in our clinics several years ago. Since 2015, we have seen numerous papers published comparing OCTA to conventional fluorescein angiography to evaluate various retinal disease states. Retina specialists are finally starting to process this flood of data. I asked Dimitra Skondra, MD, PhD, Sidney Schechet, MD, and Asadolah Movahedan, MD, to provide us with an overview of how OCTA can help us in the clinical setting to evaluate various choroidal diseases. Their approach to ...

      Read Full Article
    2. Optical Coherence Tomography Angiography of the Macula in Adults With a History of Preterm Birth

      Optical Coherence Tomography Angiography of the Macula in Adults With a History of Preterm Birth

      BACKGROUND AND OBJECTIVE: To evaluate the fovea microvasculature in adult subjects with history of preterm birth using optical coherence angiography (OCTA). PATIENTS AND METHODS: In this retrospective study, macular OCTA images were obtained from adult subjects with a history of preterm birth. The presence of the foveal avascular zone (FAZ) and its size was determined. RESULTS: Ten eyes from six subjects with ages ranging from 26 years old to 65 years old were evaluated. A distinct FAZ was not observed in three eyes (30%). The FAZ was small in other eyes, ranging from 0.07 mm 2 to 0.18 ...

      Read Full Article
    3. Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma

      Optical coherence tomography angiography (OCTA) is a new imaging technology capable of providing three-dimensional (3-D) retinal and choroidal microvascular maps without a need for exogenous dye. In this study, the authors evaluate the retinal and choroidal microvascular architecture of the macula in a patient with choroidal hemangioma using OCTA. Widefield OCTA with tracking capability and segmentation was performed to provide images with a field of view at 9 × 9 mm 2 . The en face maximum projection was used to generate 2-D angiograms of different layers with color-coded images. Variable levels of perfusion within the lesion were identified, which correlate well ...

      Read Full Article
    4. Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography

      Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography

      A patient previously diagnosed with Alport Syndrome was evaluated using multimodal imaging. Optical coherence tomography (OCT) demonstrated significant thinning of the inner retina within the macula, and inner retinal cysts were found in the peripheral macula. OCT angiography demonstrated loss of the choriocapillaris. Abnormal collagen appears to have multiple deleterious effects on the retinal and choroidal structure and vasculature.

      Read Full Article
    5. Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment

      Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment

      A 30-year-old woman with photopsias and decreased vision was diagnosed with multiple evanescent white dot syndrome (MEWDS) with an atypical inflammatory subfoveal retinal pigment epithelial detachment (PED) and imaged using swept-source optical coherence tomography (SS-OCT) during several visits. SS-OCT imaging revealed a focal area of attenuated choriocapillaris underneath the PED. An attempt to treat the presumed macular inflammatory lesion with corticosteroids resulted in bilateral exudation consistent with central serous chorioretinopathy.

      Read Full Article
    6. Optical Coherence Tomography in Children With Microtropia

      Optical Coherence Tomography in Children With Microtropia

      PURPOSE: To assess whether optical coherence tomography (OCT) could be useful for detecting and documenting fixation in patients with microtropia. METHODS: Retinal fixation observation was performed using spectral-domain OCT on amblyopic children with microtropia. The position between the retinal fixation point and the anatomical fovea was measured, in microns, using the system software tools. Only patients with a high level of cooperation, OCT scan quality signal of 7 or better, and visual acuity of 0.70 logarithm of the minimum angle of resolution (logMAR) or worse in the amblyopic eye were included. RESULTS: A total of 25 patients were included ...

      Read Full Article
    7. Evaluation of Femtosecond Laser Versus Manual Clear Corneal Incisions in Cataract Surgery Using Spectral-Domain Optical Coherence Tomography

      Evaluation of Femtosecond Laser Versus Manual Clear Corneal Incisions in Cataract Surgery Using Spectral-Domain Optical Coherence Tomography

      PURPOSE: To investigate the wound healing changes of clear corneal incisions performed with a femtosecond laser or a steel bevel knife in cataract surgery using spectral-domain optical coherence tomography. METHODS: Prospectively, consecutive patients undergoing either femtosecond laser–assisted cataract surgery (femtosecond laser group) using the LenSx laser (Alcon Laboratories, Inc., Fort Worth, TX) or traditional cataract surgery using steel blades (control group) were enrolled. The incidence of posterior wound gape, Descemet's membrane detachment, posterior wound retraction, and the inner and outer corneal incision thicknesses were assessed. RESULTS: Compared to the control group, the femtosecond laser group had significantly lower ...

      Read Full Article
    8. A New OCT Finding in Purtscher-Like Retinopathy

      A New OCT Finding in Purtscher-Like Retinopathy

      The authors report a new spectral-domain optical coherence tomography (SD-OCT) appearance observed in two patients with Purtscher-like retinopathy. In this prospective case series of three eyes of two patients with Purtscher-like retinopathy, the patients were assessed with biomicroscopy, fluorescein angiography (FA), and SD-OCT. The last examinations of the patients were performed at 3 months and 12 months, respectively. Both patients presented with decreased visual acuity. Fundus examination revealed a whitish-appearing parafoveal retina and scattered cotton-wool spots in the posterior retina. FA showed hypofluorescent spots that correspond to the cotton-wool spots and retinal hemorrhages seen clinically. SD-OCT scan of cotton-wool spots ...

      Read Full Article
    9. Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography

      Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography

      A rare case of a woman in her thirties with double optic disc pits involving opposing sectors is reported. Significantly decreased vision due to macular schisis was noted. Wide-field optical coherence tomography revealed distinct laminar defects and glial tufts associated with each pit. This case illustrates a rare view into the pathogenesis of optic disc pits.

      Read Full Article
    10. Multimodal Imaging Including Optical Coherence Tomography Angiography of a Patient With Argus II Retinal Prosthesis One Year After Implantation

      Multimodal Imaging Including Optical Coherence Tomography Angiography of a Patient With Argus II Retinal Prosthesis One Year After Implantation

      A 58-year-old man with end-stage retinitis pigmentosa (RP) and visual acuity of light perception in both eyes received simultaneous phacoemulsification with intraocular lens implantation and implantation of the Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA) to his right eye 1 year ago. He accomplished the fitting and rehabilitation sessions, and no extraocular or intraocular complications were encountered perioperatively, postoperatively, or during the follow-up. The patient used the prosthesis actively for 2.5 to 3 hours per day. In this report, the authors compare the multimodal imaging findings including optical coherence tomography angiography of the chronic electrically ...

      Read Full Article
    11. Characteristics of the Choriocapillaris Layer in Optical Coherence Tomography Angiography of Acute Central Serous Chorioretinopathy

      Characteristics of the Choriocapillaris Layer in Optical Coherence Tomography Angiography of Acute Central Serous Chorioretinopathy

      BACKGROUND AND OBJECTIVE: To describe the vascular characteristics of the choriocapillaris layer in acute central serous chorioretinopathy (CSC) imaged by optical coherence tomography angiography (OCTA), and to analyze the vascular density. PATIENTS AND METHODS: Retrospective, observational case series. In the study, 20 eyes of patients with acute CSC and 20 normal individuals were selected. All underwent OCTA, and 3 mm × 3 mm scanning mode was chosen for analyzing vascular density and morphological characteristics on the choriocapillaris layer. RESULTS: A dark region with some hyperreflective signal spots on the choriocapillaris layer was found in all affected eyes' OCTA images. The choroidal ...

      Read Full Article
    12. Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS

      Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS

      BACKGROUND AND OBJECTIVE: The aim of this study was to assess changes in retinal structure and thickness after subretinal implantation of the Retina Implant Alpha IMS (Retina Implant AG, Reutlingen, Germany). PATIENTS AND METHODS: Spectral-domain optical coherence tomography (SD-OCT) imaging was performed to assess the structure and thickness of the retina anterior to the microphotodiode array preoperatively, within 6 weeks and 6 months ± 1 month after implantation. Thickness measurements were performed using the distance tool of the built-in software. Three thickness measurements were performed in each of the four quadrants of the retina on the microchip within 6 weeks and ...

      Read Full Article
    13. Outer Retinal Changes on Spectral-Domain Optical Coherence Tomography Pre- and Post-Silicone Oil Removal

      Outer Retinal Changes on Spectral-Domain Optical Coherence Tomography Pre- and Post-Silicone Oil Removal

      BACKGROUND AND OBJECTIVE: To evaluate outer retinal changes present on spectral-domain optical coherence tomography (SD-OCT) in eyes pre- and post-silicone oil (SiO) removal (SOR). PATIENTS AND METHODS: Retrospective case series of patients who underwent pars plana vitrectomy with SiO instillation and had SD-OCT completed pre- and post-SOR. SD-OCT parameters included presence of subretinal fluid, epiretinal membrane, ellipsoid zone disruption (EZD), external limiting membrane disruption, central subfield thickness (CST), and choroidal thickness. Visual acuities (VAs) and duration of SiO instillation were recorded. RESULTS: Thirty eyes of 30 patients were included. Mean Snellen VA pre- and post-SOR was 20/762 and 20 ...

      Read Full Article
    14. Swept-Source Optical Coherence Tomography Angiography Findings in Torpedo Maculopathy

      Swept-Source Optical Coherence Tomography Angiography Findings in Torpedo Maculopathy

      Torpedo maculopathy is a rare congenital anomaly of the retinal pigment epithelium (RPE). Various imaging modalities have been used to assess cases of torpedo maculopathy, including optical coherence tomography (OCT) and fundus autofluorescence (FAF). OCT angiography (OCTA) offers combined structural and flow characteristics of imaged lesions. The authors present OCTA findings in two cases of torpedo maculopathy. Common features include loss of RPE and choriocapillaris allowing greater visualization of larger vessels in the outer choroid. This confirms the potential of OCTA to provide greater detail of retinal and choroidal architecture and elucidate the histopathology of retino-choridal lesions.

      Read Full Article
    15. OCT screening in internal medicine increases disease detection

      OCT screening in internal medicine increases disease detection

      It is no surprise that patients without a significant refractive error may wait until their 50s or even 60s before obtaining a comprehensive eye exam. Presbyopia in an emmetrope in some cases is a curse because it can be treated with store-bought reading glasses for decades. Jerome Sherman Some of the top glaucoma specialists in both optometry and ophthalmology now recommend optical coherence tomography screenings on everyone beginning at age 40. Glaucoma specialist George Cioffi, MD, chairman of the department of ophthalmology at Columbia University in New York, stated at the SUNY Glaucoma Symposium earlier this year that he supports ...

      Read Full Article
    16. DualTrack Technology Improves Optical Coherence Tomography Angiography Image Quality

      DualTrack Technology Improves Optical Coherence Tomography Angiography Image Quality

      BACKGROUND AND OBJECTIVE: To evaluate the effects of DualTrack Motion Correction Technology on the performance of AngioVue optical coherence tomography angiography (Optovue, Freemont, CA). PATIENTS AND METHODS: Fifty subjects underwent two consecutive examinations with AngioVue. The operator inactivated the eye-tracking (ET) technology before the second examination. Two operators measured execution time, excluded low-quality images, and counted the number of motion artifacts per image. RESULTS: The mean execution time was lower without ET in all the groups ( P < .05), regardless of retinal diseases. Percentages of available images and low-quality images were 75.0% and 25.0%, respectively, with ET and 63 ...

      Read Full Article
    17. Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis

      Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis

      BACKGROUND AND OBJECTIVE: To describe spectral-domain optical coherence tomography (SD-OCT) findings in eyes with endogenous fungal chorioretinitis and endophthalmitis. PATIENTS AND METHODS: Retrospective, observational case series of subjects at Wills Eye Hospital and William Beaumont Hospital were identified by screening OCT billing data and cross-referencing with patient charts. Clinical and imaging data were collected for each patient and reviewed. RESULTS: Twelve eyes of seven consecutive patients were identified, demonstrating two patterns of posterior ocular involvement: chorioretinal infiltration and superficial retinal/retinal vascular infiltration without choroidal involvement. Six of 12 eyes had follow-up imaging performed after antifungal treatment, which demonstrated decreased ...

      Read Full Article
    18. Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography

      Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography

      BACKGROUND AND OBJECTIVES: To compare choriocapillaris perfusion of the fovea between patients with idiopathic epiretinal membrane (iERM) and normal controls and determine whether surgery affects it. PATIENTS AND METHODS: Both eyes of 45 patients with iERM and 28 healthy subjects were scanned by optical coherence tomography angiography (OCTA) preoperatively, and 25 of the patients were scanned postoperatively. Central parameters measured included flow area and parafovea vessel density of the foveal choriocapillaris. RESULTS: Both parameters were significantly lower in eyes with iERM (both P < .001) compared with both the unaffected fellow eyes and the normal control eyes (both P < .001) preoperatively ...

      Read Full Article
    19. Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      Intraoperative Optical Coherence Tomography–Guided Management of Cap–Lenticule Adhesion During SMILE

      PURPOSE: To report successful lenticule extraction using intraoperative optical coherence tomography (OCT) in a case of cap–lenticule adhesion during small incision lenticule extraction (SMILE). METHODS: Case report. RESULTS: A 22-year-old patient with a refractive error of −5.00 −0.50 × 120° and −5.00 −0.75 × 60° in the right and left eyes, respectively, was scheduled for SMILE. The lenticule was created using the VisuMax femtosecond laser system (Carl Zeiss Meditec, Jena, Germany). The surgeon experienced difficulty while extracting the lenticule in the right eye. The patient was immediately shifted under the surgical microscope integrated with intraoperative OCT. The ...

      Read Full Article
    20. Noninvasive, High-Resolution Functional Macular Imaging in Subjects With Retinal Vein Occlusion

      Noninvasive, High-Resolution Functional Macular Imaging in Subjects With Retinal Vein Occlusion

      BACKGROUND AND OBJECTIVES: Several imaging modalities have been developed to characterize ischemia inherent in retinal vascular diseases. This study aims to predict the impact and to better establish the mechanisms of visual deterioration. A high-resolution functional imaging device is used, yielding quantitative data for macular blood flow and capillary network features in healthy eyes and in eyes with central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO). PATIENTS AND METHODS: This prospective, cross-sectional, comparative case series measured blood flow velocities (BFVs) and noninvasive capillary perfusion maps (nCPMs) in macular vessels in patients with BRVO/CRVO and in healthy ...

      Read Full Article
    21. Optical Coherence Tomography Angiography Findings in Punctate Inner Choroidopathy

      Optical Coherence Tomography Angiography Findings in Punctate Inner Choroidopathy

      BACKGROUND AND OBJECTIVE: Punctate inner choroidopathy (PIC) is an inflammatory chorioretinopathy characterized by multiple punctate, hypopigmented fundus lesions. Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables high-resolution visualization of the retinal and choroidal vasculature. The objective of this study is to examine the OCTA findings in PIC. PATIENTS AND METHODS: Observational, retrospective review of five patients with PIC. RESULTS: OCTA revealed several features in PIC lesions: distinctly visible choroidal neovascular membranes when present, as well as flow voids within the choroid and choriocapillaris layers that correspond with hypocyanescent lesions on indocyanine green angiography. CONCLUSION: OCTA may ...

      Read Full Article
    22. Presenter: Always image both eyes with OCT

      Presenter: Always image both eyes with OCT

      Eye care providers may have the opportunity to identify neurodegenerative diseases earlier through the use of high-resolution optical coherence tomography, according to Robert Sergott, MD, of Wills Eye Hospital. Sergott participated in the American Academy of Optometry’s plenary session, which was co-sponsored by Primary Care Optometry News. “In Alzheimer’s disease, 99% of clinical trials fail because there’s nothing left to treat. It’s diagnosed too late,” Sergott said. “This is the case for high-resolution OCT in your practice. It gives you objective vs. subjective data.” Sergott presented a number of case reports to illustrate his “rules” for ...

      Read Full Article
    23. Accuracy of a New Swept-Source Optical Coherence Tomography Biometer for IOL Power Calculation and Comparison to IOLMaster

      Accuracy of a New Swept-Source Optical Coherence Tomography Biometer for IOL Power Calculation and Comparison to IOLMaster

      PURPOSE: To investigate the accuracy of the measurements provided by a new optical biometer (OA-2000, Tomey Corporation, Nagoya, Japan) for calculating the intraocular lens (IOL) power and to compare the refractive outcomes to those obtained with the IOLMaster 500 (Carl Zeiss Meditec, Jena, Germany). METHODS: In this interventional multicenter study, consecutive patients having cataract surgery were enrolled. Only the IOL model used in the largest sample of patients was selected and the eyes implanted with that IOL were subsequently analyzed. The OA-2000, an optical biometer based on swept-source optical coherence tomography (SS-OCT), was used to measure axial length and corneal ...

      Read Full Article
    1-24 of 268 1 2 3 4 ... 10 11 12 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks