Real-Time Identification of In Situ Pulmonary Nodule and Pathology Using Optical Coherence Tomography
The incidence of indeterminate pulmonary nodules (IPN) and ground glass opacities (GGO) is increasing. Small IPN may be difficult to localize in the operating room using a minimally invasive approach. Optical coherence tomography (OCT) utilizes interference of light waves to provide high-resolution, cross-sectional images of the internal microstructure by measuring back-reflected light. This approach can deliver video rate images of tissue structure on the micron scale and can be used to identify nodules and provide realtime histology-like images without actual removal of tissue to detect lung lesions.