1. Articles from aip.scitation.org

  2. 1-4 of 4
    1. Longitudinal shear wave imaging for elasticity mapping using optical coherence elastography

      Longitudinal shear wave imaging for elasticity mapping using optical coherence elastography

      Shear wave measurements for the determination of tissue elastic properties have been used in clinical diagnosis and soft tissue assessment. A shear wave propagates as a transverse wave where vibration is perpendicular to the wave propagation direction. Previous transverse shear wave measurements could detect the shear modulus in the lateral region of the force; however, they could not provide the elastic information in the axial region of the force. In this study, we report the imaging and quantification of longitudinal shear wave propagation using optical coherence tomography to measure the elastic properties along the force direction. The experimental validation and ...

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    2. Dynamically focused optical coherence tomography for endoscopic applications

      Dynamically focused optical coherence tomography for endoscopic applications

      We report a demonstration of a small liquid-filled polymer lens that may be used to dynamically provide scanning depth focus for endoscopic optical coherence tomography (OCT) applications. The focal depth of the lens is controlled by changing the hydraulic pressure within the lens, enabling dynamic focal depth control without the need for articulated parts. The 1 mm diameter lens is shown to have resolving power of 5 μm, and can enable depth scans of 2.5 mm, making it suitable for use with OCT-enabled optical biopsy applications.

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    3. Geometric & radiometric vignetting associated with a 72-facet, off-axis, polygon mirror for swept source optical coherence tomography (SS-OCT)

      Geometric & radiometric vignetting associated with a 72-facet, off-axis, polygon mirror for swept source optical coherence tomography (SS-OCT)

      Optical Coherence Tomography (OCT) has a broad range of applications in 2D and volumetric imaging of micron scale structures typically used on inaccessible objects such as the retina of the eye. This report focuses on Swept Source OCT (SS-OCT), favoured for its faster scanning speeds and therefore faster data acquisition (highly favourable when imaging live patients). SS-OCT relies on the scanning of a narrow laser line at speeds typically in excess of 100 kHz. We have employed Zemax TM ray tracing software to simulate one method of splitting the spectrum of a broadband, near-infrared source, into its component wavelengths by ...

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    4. Volumetric Doppler angle correction for ultrahigh-resolution optical coherence Doppler tomography

      Volumetric Doppler angle correction for ultrahigh-resolution optical coherence Doppler tomography

      Ultrahigh-resolution optical coherence Doppler tomography (μODT) demonstrates great potential for quantitative blood flow imaging owing to its large field of view and capillary resolution. However, μODT only detects the axial flow velocity and requires Doppler angle correction to retrieve the absolute velocity. Although methods for Doppler angle tracking of single or few large vessels have been reported, a method that enables angle correction of the entire 3D microvascular networks remains a challenge. Here, we present a method based on eigenvalue analysis of 3D Hessian matrix to retrieve the orientation of each tubular vessel. As the algorithm is voxel based, it ...

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    1-4 of 4
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