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    1. Optical coherence tomography in imaging of peripheral pulmonary arteries

      Optical coherence tomography in imaging of peripheral pulmonary arteries

      Background: To establish an optical coherence tomography (OCT)-based method for imaging peripheral pulmonary arteries. Methods: We recruited eight patients (five men; average age, 48±12 years; peripheral pulmonary artery thrombosis, three patients; idiopathic pulmonary hypertension, three patients; interstitial lung disease, two patients) who underwent OCT of the peripheral pulmonary arteries in the First Affiliated Hospital of Guangzhou Medical University and Guangzhou Institute of Respiratory Diseases, between September 2009 and September 2010. OCT was performed using both the conventional OCT imaging method (COI) and the improved pulmonary artery imaging method (IPI). In the IPI, contrast agent was used as an ...

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    2. Optical coherence tomography- vs. intravascular ultrasound-guided percutaneous coronary intervention (Editorial)

      Optical coherence tomography- vs. intravascular ultrasound-guided percutaneous coronary intervention (Editorial)

      Coronary angiography is routinely used to guide percutaneous coronary interventions (PCI) despite obvious limitations of this lumen based approach. Intravascular imaging including intravascular ultrasound (IVUS) and optical coherence tomography (OCT) represent two techniques that provide essential information on pre-procedural lesion characteristics (i.e., lesion severity, landing zone, and plaque composition) and the result after stent implantation (i.e., stent expansion and eccentricity, strut apposition, lesion coverage, tissue protrusion, and dissections). A total of 11 randomized controlled trials investigated the effect of IVUS-guided PCI with mixed results ( 1 - 11 ). Of note, studies including patients with an increased complexity [i.e., chronic ...

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    3. Re-crossing the distal cell in bifurcation verified by using an enhanced stent visualization system and optical coherence tomography: a report of two cases

      Re-crossing the distal cell in bifurcation verified by using an enhanced stent visualization system and optical coherence tomography: a report of two cases

      The coronary guidewire re-crossing position before the final kissing balloon post-dilation is important to reduce the incidence of incomplete stent apposition in bifurcation lesions. Angiography and intravascular ultrasonography are unreliable at detecting the site of wire re-crossing. The high resolution of optical coherence tomography (OCT) offers the advantage of precise assessment of construction in bifurcation. However, the OCT technique still has some limitations, including the requirement for additional contrast and expense. We present two cases where the ClearStent Live system technique was used to estimate the wire location, which was verified by using OCT. In conclusion, ClearStent can be used ...

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    4. Shedding light on the mechanisms of stent thrombosis with optical coherence tomography

      Shedding light on the mechanisms of stent thrombosis with optical coherence tomography

      Since the introduction of mechanical devices for the treatment of stenotic coronary artery disease, stent thrombosis (ST) has been an issue of major clinical concern. It is an uncommon but serious complication with high mortality and morbidity that almost always presents as death or myocardial infarction (MI), usually with electrocardiographic ST-segment elevation ( 1 ). Inadequate stent expansion and undersizing of a stent has been recognized as the main reason for acute and subacute ST ( 2 ) following stent implantation. Souteyrand et al . ( 3 ) have done a great job at confirming these findings with the use of optical coherence tomography (OCT). It is ...

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    5. Mechanisms of stent thrombosis: insights from optical coherence tomography

      Mechanisms of stent thrombosis: insights from optical coherence tomography

      Although the improvement of coronary stents and medical agents has reduced adverse cardiac events in patients undergoing percutaneous coronary intervention (PCI), stent thrombosis (ST) still remains one of fatal complications of stent therapy. However, the pathophysiology of ST has not been sufficiently established yet, and factors including comorbidities such as diabetes mellitus, stent design, and patients’ response or adherence to antiplatelet therapy have had the association with ST occurrence (1,2). Recently, a large prospective registry study investigating the intravascular morphologies of coronary stents in patients suffering from ST was published (3). Using optical coherence tomography (OCT) that had higher ...

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    6. Clinical perspective of Optical Coherence Tomography and Intravascular Ultrasound in STEMI patients

      Clinical perspective of Optical Coherence Tomography and Intravascular Ultrasound in STEMI patients

      In the last years, the Intravascular Ultrasound Study (IVUS) and further the Optical Coherence Tomography (OCT) became two helpful tools to characterize of the atherosclerotic plaque. These new technologies made possible to analyse in vivo the pathophysiologic mechanisms that previously were just speculated or observed post-mortem (1). Recently Dr. Higum and Prof. Jang published an interesting article named “A combined OCT and IVUS on plaque rupture, plaque erosion and calcified nodule in patients with STEMI”, useful to describe the different presentation of culprit lesions in STelevation myocardial infarction (2). In this paper the authors describe the findings about 112 STEMI ...

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