1. 1-4 of 4
    1. Multianalysis with optical coherence tomography and vasomotion in everolimus-eluting stents and everolimus-eluting biovascular scaffolds: the MOVES trial

      Multianalysis with optical coherence tomography and vasomotion in everolimus-eluting stents and everolimus-eluting biovascular scaffolds: the MOVES trial

      Aims To compare endothelium-dependent vasomotor function and vascular healing 15 months after implantation of two new-generation drug-eluting stents and biovascular scaffolds (BVS). Methods and results A total of 28 patients previously treated with a SYNERGY stent (bioabsorbable polymer everolimus-eluting stents (BP-EES)), a PROMUS stent (persistent polymer everolimus-eluting stents (PP-EES)) or an ABSORB (BVS) underwent control coronary angiography, 15 months after implantation, coupled with optical coherence tomography imaging and supine bicycle exercise. Intracoronary nitroglycerin was administered after exercise testing. Coronary vasomotor response was assessed using quantitative coronary angiography at rest, during supine bicycle exercise and after nitroglycerin. The primary end point ...

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    2. FD-OCT and IVUS for detection of incomplete stent apposition in heavily calcified vessels: novel insights

      FD-OCT and IVUS for detection of incomplete stent apposition in heavily calcified vessels: novel insights

      In the present issue of Open Heart , Gudmundsdottir and colleagues compare two intracoronary imaging modalities, intravascular ultrasound (IVUS) and FD-optical coherence tomography (FD-OCT), in patients undergoing complex percutaneous coronary intervention (PCI) with rotablation for calcific coronary lesions. In particular, this study sought to detect incomplete stent apposition (ISA) using these different imaging modalities. ISA may play a role in the risk of target vessel failure, for example, stent thrombosis. 1 Intracoronary imaging has become widely available with the advent of IVUS in the early 1990s. 2 IVUS-derived images with an axial resolution down to 150 µm have given novel insights ...

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    3. Optical coherence tomography versus intravascular ultrasound to evaluate stent implantation in patients with calcific coronary artery disease -- Gudmundsdottir et al. 2 (1) -- Open Heart

      Optical coherence tomography versus intravascular ultrasound to evaluate stent implantation in patients with calcific coronary artery disease -- Gudmundsdottir et al. 2 (1) -- Open Heart

      Aims Stent underexpansion and malapposition are associated with adverse outcomes following percutaneous coronary intervention, but detection and treatment can be challenging in the presence of extensive coronary artery calcification. Frequency domain optical coherence tomography (FD-OCT) is a novel intravascular imaging technique with greater spatial resolution than intravascular ultrasound (IVUS) but its role in the presence of extensive coronary calcification remains unclear. We sought to determine the utility of FD-OCT compared to IVUS imaging to guide percutaneous coronary intervention in patients with severe calcific coronary artery disease. Methods 18 matched IVUS and FD-OCT examinations were evaluated following coronary stent implantation in ...

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    4. Optical coherence tomography for serial in vivo imaging of aortic plaque in the rabbit: a preliminary experience

      Optical coherence tomography for serial in vivo imaging of aortic plaque in the rabbit: a preliminary experience

      Background In this pilot feasibility study, we aimed to establish a reproducible means of performing serial optical coherence tomography (OCT) procedures in the abdominal aorta of the cholesterol-fed rabbit. Methods Eight cholesterol-fed New Zealand White rabbits were assigned to abdominal aortic balloon injury at baseline (n=6) or as controls (n=2). Three of the balloon injured rabbits received statins from weeks 6 to 12 post balloon injury. OCT of the abdominal aorta in each rabbit was performed at baseline±week 6±week 12 via alternate vascular access points (left or right femoral artery or left carotid artery). OCT sequences ...

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    1-4 of 4
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