1. Articles from jovr.org

  2. 1-22 of 22
    1. The effect of panretinal photocoagulation (PRP) versus intravitreal bevacizumab (IVB) plus prp on peripapillary retinal nerve fiber layer (RNFL) thickness analyzed by optical coherence tomography in patients with proliferative diabetic retinopathy

      The effect of panretinal photocoagulation (PRP) versus intravitreal bevacizumab (IVB) plus prp on peripapillary retinal nerve fiber layer (RNFL) thickness analyzed by optical coherence tomography in patients with proliferative diabetic retinopathy

      Purpose: The current study aimed to evaluate changes in peripapillary retinal nerve fiber layer (RNFL) thickness in diabetic patients with bilateral proliferative diabetic retinopathy (PDR) after receiving panretinal photocoagulation (PRP) or intravitreal bevacizumab (IVB) with PRP. Methods: Ocular examination and peripapillary optical coherent tomography (OCT) were performed for each patient at baseline, 1, 3, 6, and 10 months after treatment. Both eyes of each patient were randomized into either PRP or PRP + IVB group. Results: Sixty-four eyes (32 patients) were enrolled in this randomized clinical trial. In the PRP group, global RNFL thickness initially increased and reached statistical significance in ...

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    2. Intraoperative optical coherence tomography of a dislocated intraocular lens

      Intraoperative optical coherence tomography of a dislocated intraocular lens

      An 88-year-old female with pseudoexfoliation syndrome presented with sudden vision loss and was found to have a dislocated one piece intraocular lens (IOL) that was resting on the retina. She underwent 23-gauge pars plana vitrectomy, IOL explantation, and anterior chamber IOL insertion. Intraoperative optical coherence tomography (EnFocus iOCT; Leica, Wetzlar, Germany) was used to assess the position and vault of the IOL on the retinal surface [Figure 1] a. Utilization of iOCT enabled the surgeon to safely grasp the IOL with forceps in the location with the greatest vault in order to minimize any potential trauma to the retina [Figure ...

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    3. Peripapillary retinal nerve fiber layer thickness in normal iranian children measured with optical coherence tomography

      Peripapillary retinal nerve fiber layer thickness in normal iranian children measured with optical coherence tomography

      Purpose: This study aimed to measure the peripapillary retinal nerve fiber layer (RNFL) thickness using spectral-domain optical coherence tomography (SD-OCT) in normal Iranian children aged below 18 years. Methods: Peripapillary RNFL imaging was performed in the right eye of normal Iranian children aged below 18 years using Spectralis SD-OCT (Heidelberg Engineering; Vista, CA). The effects of age, gender, cup-to-disc ratio, and spherical equivalent (SE) on global and sectoral RNFL thicknesses were evaluated. Results: A total of 115 eyes were imaged. Approximately 51 (44.3%) of the cases were female children. The mean age was 12.44 ± 2.52 years. The ...

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    4. Foveal avascular zone and vessel density in healthy subjects: An optical coherence tomography angiography study

      Foveal avascular zone and vessel density in healthy subjects: An optical coherence tomography angiography study

      Purpose: To report the normal characteristics and correlations of the foveal microvascular networks using optical coherence tomography angiography (OCTA) in a healthy Iranian population. Methods: Enface 3x3 OCTA images were obtained using the RTVue Avanti spectral-domain optical coherence tomography with AngioVue software (Optovue, Fremont, CA, USA). Foveal avascular zone (FAZ) area, central foveal point thickness and inner retinal thickness at the foveal center and the vascular density of the superficial retinal capillary plexus (SCP) and deep retinal capillary plexus (DCP) in the fovea were recorded. Results: Seventy normal eyes of 70 subjects (range, 9 to 71 years) were studied. Mean ...

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    5. Optical coherence tomography angiography in eyes with retinal vein occlusion

      Optical coherence tomography angiography in eyes with retinal vein occlusion

      Optical coherence angiography (OCTA) is a noninvasive technique that has been introduced in recent years to detect ophthalmological pathology. The growing usage of OCTA to detect retinal abnormalities can be attributed to its advantages over the reference-standard fluorescein angiography (FA), although both of these techniques can be used in association. OCTA's advantages include its dye independency, its ability to produce depth-resolved images of retinal and choroidal vessels that yield images of different vascular layers of the retina, and the better delineation of the foveal avascular zone. OCTA's disadvantages include the lack of normalized patient data, artefactual projection issues ...

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      Mentions: Cleveland Clinic
    6. Visibility of blood flow on optical coherence tomography angiography in a case of branch retinal artery occlusion

      Visibility of blood flow on optical coherence tomography angiography in a case of branch retinal artery occlusion

      Purpose: We report the variability in flow angiogram during the course of branch retinal artery occlusion (BRAO) in a case imaged by optical coherence tomography angiography (OCTA). Case Report: OCTA was performed in a patient with BRAO at initial examination and 6 hours later. Initially, the occluded retinal artery and its branches were not detected on OCTA whereas a slow perfusion was present on fluorescein angiography. Six hours after initial examination, flow was detected on OCTA image in the previously occluded artery. Conclusion: This case confirmed the relevance of using OCTA in monitoring BRAO and showed that capillaries with a ...

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    7. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      iabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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    8. Temporal and spatial flap variability in laser in-situ keratomileusis by optical coherence tomography

      Temporal and spatial flap variability in laser in-situ keratomileusis by optical coherence tomography

      Purpose: To study changes in flap thickness made with two different microkeratome heads across different corneal locations using anterior segment optical coherence tomography (OCT). Methods: In this prospective, non-randomized, consecutive case series, subjects who had their laser in-situ keratomileusis (LASIK) flaps made using 90 μm (MSU90) or 130 μm (MSU130) disposable M2 microkeratome heads were examined using OCT. The measurements were performed at three locations (central and 2.5 mm to either side) at 1 day, 1 week, and 1 month postoperatively. Results: The central flap thickness was 123 ± 15, 130 ± 14, and 127 ± 13 μm, respectively, at 1 day ...

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    9. Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Optical coherence tomography angiography as an imaging modality for evaluation of diabetic macular edema

      Diabetic retinopathy remains a leading cause of blindness worldwide in patients aged 20–64 years. [1] Diabetic macular edema (DME) threating or involving the fovea is a common etiology for vision loss. Traditionally, treatment methods have been guided by contact and non-contact slit lamp biomicroscopy, fluorescein angiography and fundus stereo photography. [1] Fluorescein angiography (FA) is a dynamic, invasive imaging technique first described in 1961 and more thoroughly invested and popularized by Gass in 1967. [2] In principle, this technique uses a series of exciting and barrier filters to visualize fluorescein dye excursion through retinal arterial, capillary, and venous structures ...

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    10. Optical coherence tomography angiography: A new tool in glaucoma diagnostics and research

      Optical coherence tomography angiography: A new tool in glaucoma diagnostics and research

      Optical coherence tomography angiography (OCTA) is a new modality in ocular imaging which provides high resolution view of the vascular structures in the retina and optic nerve head. This technology has the advantages of being noninvasive, rapid and reproducible. OCTA is becoming a valuable tool for evaluating many retinal and optic nerve diseases. This article provides a brief introduction to the technology and its application in the field of glaucoma diagnostics.

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      Mentions: UCLA
    11. Spectral domain optical coherence tomography features of traumatic macular retinoschisis

      Spectral domain optical coherence tomography features of traumatic macular retinoschisis

      A 30-year-old man noticed acute visual loss in his left eye following explosion of a vehicle tire tube while inflating. On presentation, Snellen visual acuity (VA) was 20/20 in the right eye and 2 meters counting fingers in the left eye. Relative afferent pupillary defect was negative. A small area of temporal conjunctival hemorrhage, anterior chamber red blood cells (1+), and inferotemporal iridodialysis extending 3 clock hours were evident on slit lamp biomicroscopy. Fundus examination revealed thickening and yellow discoloration of the macula and a mild vitreous hemorrhage [Figure 1] . Figure 1: Infrar

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    12. Optical coherence tomography angiography of the optic disc; an overview

      Optical coherence tomography angiography of the optic disc; an overview

      Different diseases of the optic disc may be caused by or lead to abnormal vasculature at the optic nerve head. Optical coherence tomography angiography (OCTA) is a novel technology that provides high resolution mapping of the retinal and optic disc vessels. Recent studies have shown the ability of OCTA to visualize vascular abnormalities in different optic neuropathies. In addition, quantified OCTA measurements were found promising for differentiating optic neuropathies from healthy eyes.

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    13. Bilateral photic maculopathy following pterygium excision: Spectral domain optical coherence tomography findings

      Bilateral photic maculopathy following pterygium excision: Spectral domain optical coherence tomography findings

      Purpose: To report high resolution spectral domain optical coherence tomography (SD-OCT) findings in a case with bilateral photic maculopathy and resultant central scotoma following pterygium excision. Case Report: A 38-year-old man with a history of pterygium excision complained of visual disturbance and annoying central scotoma in both eyes. Although he had subtle funduscopic and angiographic changes, SD-OCT precisely showed disruption of the photoreceptors inner segment/outer segment in the foveal center. Conclusion: Phototoxic macular damage following ocular surgeries may be diagnosed with difficulty due to subtle funduscopic findings. SD-OCT is a precise imaging in revealing characteristic retinal alterations in different ...

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    14. Intraoperative optical coherence tomography guided bleb needling

      Intraoperative optical coherence tomography guided bleb needling

      Two patients with history of trabeculectomy presented with uncontrolled intraocular pressure (IOP) postoperatively. The first patient had a flat and vasularized bleb 10 weeks after the surgery, and the second subject developed encapsulated bleb 3 months postoperatively. Both patients were taken to the operating room and intraoperative optical coherence tomography (OCT) guided bleb needling was performed to restore aqueous egress into the subconjunctival space. Postoperatively, IOP of the operated eyes ranged 14-18 mmHg at week 6 and month 3. None of the eyes had any intraoperative or postoperative complications. This novel application of the intraoperative OCT for bleb needling facilitates ...

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    15. Optical coherence tomography angiography in retinal diseases

      Optical coherence tomography angiography in retinal diseases

      Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system that generates volumetric data of retinal and choroidal layers. It has the ability to show both structural and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithm (a vital component of OCTA software) helps to decrease the signal to noise ratio of flow detection thus enhancing visualization of retinal vasculature using motion contrast. Published studies describe potential efficacy for OCTA in the evaluation of common ophthalmologic diseases such as diabetic retinopathy, age related macular degeneration (AMD), retinal vascular occlusions and sickle cell disease. OCTA provides a detailed view of the ...

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    16. High myopic peripapillary atrophy; Spectral domain optical coherence tomography features

      High myopic peripapillary atrophy; Spectral domain optical coherence tomography features

      Pathologic myopia is defined as myopic refractive error greater than -6.00 diopters (D). [1] Axial myopia progression results in stretching of ocular layers which may be imaged by optical coherence tomography (OCT). These findings consist of dehiscence of retinal layers, retinal cysts, intrachoroidal cavitation, macular holes, posterior retinal detachment and choroidal neovascular membranes. [2] Furthermore, it has been suggested that scleral protrusion temporal to the optic disc in highly myopic eyes could cause excessive tension on the retinal nerve fiber layer which may result in visual field defects. [3] A 72-year-old woman was referred to the ophthalmology clinic complaining ...

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    17. Unilateral ischemic maculopathy associated with cytomegalovirus retinitis in patients with AIDS: Optical coherence tomography findings

      Unilateral ischemic maculopathy associated with cytomegalovirus retinitis in patients with AIDS: Optical coherence tomography findings

      To describe the clinical and optical coherence tomography (OCT) characteristics of ischemic maculopathy in two patients with acquired immunodeficiency syndrome (AIDS). Two patients with AIDS and cytomegalovirus (CMV) retinitis developed ischemic maculopathy. Both patients presented with central visual loss and active granular CMV retinitis. The presence of opacification of the superficial retina in the macular area and intraretinal edema suggested the diagnosis. Fluorescein angiography changes were similar in the two cases with enlargement of the foveal avascular zone and late staining of juxtafoveal vessels. OCT changes were suggestive of retinal ischemia: Increased reflectivity from the inner retinal layer and decreased ...

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    18. Intraoperative spectral domain optical coherence tomography; Its time has come

      Intraoperative spectral domain optical coherence tomography; Its time has come

      Vitreoretinal surgery has experienced an explosion of advances in the last decade and a half. New advances in pars plana vitrectomy systems including small-gauge instrumentation have provided many potential benefits to patients and surgeons. These include more efficient surgery; decreased postoperative inflammation leading to less pain and more patient comfort; improved cosmetic appearance following surgery; decreased astigmatic changes; and more rapid visual recovery. Pharmacotherapy and chromovitrectomy have facilitated pars plana vitrectomy and peeling of membranes. Better visualization with better microscopes and optics is also available. Advances and technology continue to add to the explosion of possibilities available in our armamentarium ...

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    19. Macular surgery using intraoperative spectral domain optical coherence tomography

      Macular surgery using intraoperative spectral domain optical coherence tomography

      Purpose: To report the use of intraoperative spectral domain optical coherence tomography (SD-OCT) for detecting anatomical changes during macular surgery. Methods: In a consecutive case series, 32 eyes of 32 patients undergoing concurrent pars plana vitrectomy and intraoperative SD-OCT for macular hole (MH), epiretinal membrane (ERM) and vitreomacular traction (VMT) were enrolled. Intraoperative changes in retinal thickness and dimensions of the macular hole were measured in patients with ERM and VMT following surgical manipulation using a hand-held SD-OCT device (iVue, Optovue Inc., Fremont, CA, USA). Results: SD-OCT images of sixteen eyes with macular hole were subjected to quantitative and qualitative ...

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    20. Multifocal electroretinogram in diabetic macular edema; Correlation with visual acuity and optical coherence tomography

      Multifocal electroretinogram in diabetic macular edema; Correlation with visual acuity and optical coherence tomography

      Purpose: To evaluate multifocal electroretinogram (mfERG) changes in eyes with diabetic macular edema (DME) and investigate any possible correlation with optical coherence tomography (OCT) features and visual acuity (VA). Methods: Twenty-nine right eyes of 29 subjects with DME due to non-proliferative diabetic retinopathy and 30 eyes of 30 normal subjects were evaluated. All patients underwent a complete ophthalmic examination. Sixty-one scaled hexagon mfERG responses were recorded. Components of thefirst order kernel of N1, N2, and P1 in five concentric rings centered on the fovea, were measured in both groups. Correlation and regression analyses were performed among VA, central macular thickness ...

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    21. Optical Coherence Tomography Features in Idiopathic Retinal Vasculitis, Aneurysms and Neuroretinitis Syndrome

      Optical Coherence Tomography Features in Idiopathic Retinal Vasculitis, Aneurysms and Neuroretinitis Syndrome

      A 15-year-old girl complaining of reduced visual acuity (VA) in both eyes since 2 months before was referred to our retina service in January 2011. Best corrected visual acuity was 5/10 in both eyes. External eye examination was normal. Biomicroscopy revealed +1 anterior chamber cells and +1 old vitreous cells bilaterally. Other anterior segment structures and intraocular pressure (IOP) were normal in both eyes. Fundus examination revealed the presence of circinate exudative maculopathy, optic disc swelling, multiple tied knot-like aneurysmal dilations of peripapillary and optic disc retinal arterioles (macro-aneurysms), and diffuse retinal vasculitis, bilaterally [Figure 1] .

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    22. Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis

      Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis

      PURPOSE: To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro). METHODS: In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interface, epithelial interaction at the keratoprosthesis edge and the keratoprosthesis-cornea interface gap. RESULTS: Ten patients including 4 male and 6 female subjects with different preoperative diagnoses, i.e. 8 multiple corneal graft failures and 2 immunological ocular surface diseases, were studied. Mean age was 62.1 ± 20.0 (range, 33.0-83.0 ...

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    1-22 of 22
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