1. 1-4 of 4
    1. Cumulative Sum Analysis of the Learning Curve for Optical Coherence Tomography Assisted Diagnosis of Basal Cell Carcinoma

      Cumulative Sum Analysis of the Learning Curve for Optical Coherence Tomography Assisted Diagnosis of Basal Cell Carcinoma

      The amount of training needed to correctly interpret optical coherence tomography scans of the skin is undefined. The aim of this study was to illustrate how cumulative sum charts can be used to determine how many optical coherence tomography scans novice assessors should evaluate in order to obtain competence in diagnosing basal cell carcinoma. Four hundred lesions suspect for non-melanoma skin cancer were evaluated by optical coherence tomography in combination with clinical photographs, using a 5-point confidence scale. The diagnostic error rate (sum of false-negative and false-positive optical coherence tomography results/total number of cases) was used to evaluate performance ...

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      Mentions: Julia Welzel
    2. Non-invasive Imaging of Localised Scleroderma for Assessment of Skin Blood Flow and Structure

      Non-invasive Imaging of Localised Scleroderma for Assessment of Skin Blood Flow and Structure

      xtensive morphoea causes major morbidity, disability and disfigurement; pathophysiology is poorly understood. The aim of this study was to investigate, with non-invasive imaging, the relationship between localised abnormalities of skin structure and perfusion, which characterise morphoea. Thirty-two patients with mor­phoea underwent imaging at affected and unaffected sites. Skin thickness was imaged with optical coherence tomography (OCT) and high-frequency ultrasound (HFUS). Perfusion was imaged with dual-wavelength laser Doppler imaging (LDI) and thermography. Epidermal thickness showed a small increase from affected to unaffected site (OCT, active and inactive plaques [ p = 0.005 and p = 0.004], HFUS active plaques only [ p ...

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    3. Preoperative Characterization of Basal Cell Carcinoma Comparing Tumour Thickness Measurement by Optical Coherence Tomography, 20-MHz Ultrasound and Histopathology

      Preoperative Characterization of Basal Cell Carcinoma Comparing Tumour Thickness Measurement by Optical Coherence Tomography, 20-MHz Ultrasound and Histopathology
      Optical coherence tomography (OCT) is a new imaging method with promising results for several dermatological indications, including preoperative skin tumour characterization. While high-frequency ultrasound (HFUS) is frequently used for this purpose, overestimation of tumour thickness is a problem, due to subtumoral inflammatory infiltration that cannot be differentiated from tumour tissue. The aim of this single-centre study was to describe OCT features of basal cell carcinoma (BCC) and to determine vertical tumour thickness accurately, including a comparison with HFUS and histopathology. Tumour thickness values of 10 BCCs measured by OCT did not differ significantly from those measured by histopathology (median difference ...
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    1-4 of 4
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