1. 1-7 of 7
    1. Evaluating tear clearance rate with optical coherence tomography

      Evaluating tear clearance rate with optical coherence tomography

      To assess the early-phase of tear clearance rate (TCR) with anterior segment optical coherence tomography (OCT) and to determine the association between TCR and other clinical measures of the tear film in a group of young subjects with different levels of tear film quality. Methods TCR was classified as the percentage decrease of subject’s inferior tear meniscus height 30 s after instillation of 5 μl 0.9% saline solution. Fifty subjects (32F and 18M) aged (mean ± standard deviation) 25.5 ± 4.3 years volunteered for the study. It consisted of a review of medical history, Ocular Surface Disease Index ...

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    2. Scleral topography analysed by optical coherence tomography

      Scleral topography analysed by optical coherence tomography

      Purpose A detailed evaluation of the corneo-scleral-profile (CSP) is of particular relevance in soft and scleral lenses fitting. The aim of this study was to use optical coherence tomography (OCT) to analyse the profile of the limbal sclera and to evaluate the relationship between central corneal radii, corneal eccentricity and scleral radii. Methods Using OCT (Optos OCT/SLO; Dunfermline, Scotland, UK) the limbal scleral radii (SR) of 30 subjects (11 M, 19F; mean age 23.8 ± 2.0SD years) were measured in eight meridians 45° apart. Central corneal radii (CR) and corneal eccentricity (CE) were evaluated using the Oculus Keratograph ...

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      Mentions: Optos
    3. Developments in contact lens measurement: A comparative study of industry standard geometric inspection and optical coherence tomography

      Developments in contact lens measurement: A comparative study of industry standard geometric inspection and optical coherence tomography

      Purpose The aim of this study was to compare a developmental optical coherence tomography (OCT) based contact lens inspection instrument to a widely used geometric inspection instrument (Optimec JCF), to establish the capability of a market focused OCT system. Methods Measurements of 27 soft spherical contact lenses were made using the Optimec JCF and a new OCT based instrument, the Optimec is830. Twelve of the lenses analysed were specially commissioned from a traditional hydrogel (Contamac GM Advance 49%) and 12 from a silicone hydrogel (Contamac Definitive 65), each set with a range of back optic zone radius (BOZR) and centre ...

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      Mentions: Kate Sugden
    4. A program to analyse optical coherence tomography images of the ciliary muscle

      A program to analyse optical coherence tomography images of the ciliary muscle

      Purpose To describe and validate bespoke software designed to extract morphometric data from ciliary muscle Visante Anterior Segment Optical Coherence Tomography (AS-OCT) images. Method Initially, to ensure the software was capable of appropriately applying tiered refractive index corrections and accurately measuring orthogonal and oblique parameters, 5 sets of custom-made rigid gas-permeable lenses aligned to simulate the sclera and ciliary muscle were imaged by the Visante AS-OCT and were analysed by the software. Human temporal ciliary muscle data from 50 participants extracted via the internal Visante AS-OCT caliper method and the software were compared. The repeatability of the software was also ...

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    5. Repeatability of tear meniscus evaluation using spectral-domain Cirrus® HD-OCT and time-domain Visante® OCT

      Repeatability of tear meniscus evaluation using spectral-domain Cirrus® HD-OCT and time-domain Visante® OCT

      Purpose To investigate the intra-rater, inter-rater and inter-device repeatability of a spectral-domain OCT (Cirrus) and a time-domain OCT (Visante) for tear meniscus height (TMH) and area (TMA) measurements. Methods 20 participants with no known eye disease were recruited. Both eyes of participants were imaged with both OCTs under the similar conditions. The inferior tear meniscus was imaged at 6 o’clock position whereas the superior meniscus was imaged at 12 o’clock position. Data from the right eyes was analyzed. Two raters independently measured TMH and TMA using the OCT images, and one rater repeated the measurements. Intra-rater, inter-rater and ...

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    6. The palpebral conjunctival epithelium thickness in young adults measured by optical coherence tomography

      The palpebral conjunctival epithelium thickness in young adults measured by optical coherence tomography

      Objective To measure the palpebral conjunctival epithelium thickness in young adults with optical coherence tomography (OCT). Methods A Cirrus HD-OCT 4000 system was used to image the superior palpebral conjunctival with the Anterior Segment 5 Line Raster scanning protocol at the central region in 36 male and 26 female subjects aged between 20 and 30 years of age with normal, healthy eyes. The palpebral conjunctival epithelium thickness was measured according to the difference in brightness on OCT between the epithelium and its underlying substantia propria. The measurements were respectively performed in the same subjects by two operators and the Bland ...

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    7. Compare the effects of two silicone-hydrogel bandage contact lenses on epithelial healing after photorefractive keratectomy with anterior segment optical coherence tomography

      Compare the effects of two silicone-hydrogel bandage contact lenses on epithelial healing after photorefractive keratectomy with anterior segment optical coherence tomography

      Purpose To evaluate the efficacy of two silicone hydrogel bandage lenses (SiHy) on epithelial healing following photorefractive keratectomy (PRK) with anterior segment optical coherence tomography (AS-OCT). Methods Forty-two eyes of 21 patients who underwent PRK were included in a contralateral eye comparison study. At the end of the procedure, one eye of each patient was fitted with a Lotrafilcon B contact lens whereas the fellow eye was fitted with a Comfilicon A lens. Patients were examined on the day of surgery and at days 1–5 postoperatively. Main outcome measures were number of reepithelialized eyes, epithelial defect size, patient discomfort ...

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    1-7 of 7
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