1. 1-4 of 4
    1. Optical coherence tomography findings in a patient with type 1 sialidosis

      Optical coherence tomography findings in a patient with type 1 sialidosis

      Type 1 sialidosis is a metabolic storage disorder characterised by the accumulation of sialylated oligosaccharides. The condition is also known as macular cherry-red spot and myoclonus syndrome due to the characteristic macular appearance in affected individuals. This case outlines the presentation of a patient with type 1 sialidosis, including ophthalmological assessment with retinal photography and spectral domain optical coherence tomography (OCT). OCT scans showed thickening of the perimacular and peripapillary retinal nerve fibre layer, thought to be due to the abnormal accumulation of metabolic products. The cherry-red spot appearance is due to the normal appearing macula being seen in contrast ...

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    2. Optical coherence tomography of the optic nerve head detects acute changes in intracranial pressure

      Optical coherence tomography of the optic nerve head detects acute changes in intracranial pressure

      We aimed to determine if there are measurable objective changes in the optic nerve head (ONH) immediately after cerebrospinal fluid (CSF) drainage in a prospective case-series of five patients undergoing a clinically indicated lumbar puncture (LP) for diagnosis of idiopathic intracranial hypertension. A Cirrus high-definition optical coherence tomography machine (Carl Zeiss Meditec, Dublin, CA, USA) was used to acquire images in the lateral decubitus position. Optic disc cube and high-definition line raster scans centered on the ONH were obtained immediately before and after draining CSF, while the patient maintained the lateral decubitus position. Measured parameters included retinal nerve fiber layer ...

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    3. Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia

      Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia

      We report four patients with monocular visual loss for whom optical coherence tomography (OCT) was helpful in distinguishing the sequelae of retinal artery occlusion from those of primary optic neuropathy. Determinations of the peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular retinal layer thicknesses and architecture were used. The major findings in our patients show that changes in the inner retinal layers (including ganglion cell and inner plexiform layer) with disruption of normal macular architecture supports a diagnosis of retinal artery occlusion. Our results support the use of OCT imaging for patients with monocular visual loss of ...

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      Mentions: Laura J. Balcer
    4. Optical coherence tomography predicts visual outcome for pituitary tumors

      Optical coherence tomography predicts visual outcome for pituitary tumors

      We evaluate if the relationship between optical coherence tomography (OCT) of the retinal nerve fibre layer (RNFL) continued over long-term visual recovery in 107 patients undergoing pituitary decompression. Recently, it has been recognized that OCT of RNFL has prognostic value in predicting visual outcomes after surgery for chiasmal compression caused by pituitary tumours. Patients were followed up at three time points: pre-operative (visit 1), 6 –10 weeks post-operative (visit 2) and 9–15 months follow-up (visit 3). We found that patients with thin pre-operative RNFL had more severe visual field defects (mean deviation [MD] -9.22 versus -3.96 decibels ...

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    1-4 of 4
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