1. Articles from osa-opn.org

  2. 1-9 of 9
    1. Macro-Scale OCT-on-a-Chip

      Macro-Scale OCT-on-a-Chip

      A U.S. industry-academic collaboration, led by OSA Fellow James Fujimoto, Massachusetts Institute of Technology (MIT; USA), reports a proof-of-principle demonstration of cubic-meter volume optical coherence tomography (OCT). The researchers used advanced photonics integrated circuits (PICs) and MEMS technology to boost OCT performance on multiple scales over long ranges. Specifically, the team demonstrated 3-D subsurface tomographic imaging on a meter scale at a 100-kHz axial scan rate with 15-µm depth resolution ( Optica , doi: 10.1364/OPTICA.3.001496 ). OCT is a 3-D imaging technology commonly used in ophthalmology to get micron-scale images of small structures in the human eye ...

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    2. Optical Modalities for Embryonic Imaging

      Optical Modalities for Embryonic Imaging

      tudies of disease etiology often rely on the murine (mouse) model, which provides valuable genotypic information. Yet associated phenotypic information from murine embryos is often lacking. Of the various techniques that have been proposed for imaging such embryos, optical modalities may provide the best compromise among speed, penetration depth and resolution. This year, we developed approaches to improve embryonic imaging with optical coherence tomography (OCT), 1 and also provided a detailed comparison of OCT and another modality, optical projection tomography (OPT), in murine-embryo studies. 2 Most commonly used for ophthalmological imaging, 3 OCT has proved a powerful embryonic-imaging modality as ...

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    3. A 4-D OCT Engine with 1 GVoxel/s

      A 4-D OCT Engine with 1 GVoxel/s

      Optical coherence tomography (OCT) is a depth-resolved imaging modality that provides micrometer-scale cross-sectional and 3-D information on the scattering properties of biological samples. 1 Video rate real-time 3-D volumetric OCT (4-D-OCT) could generate a new class of optical tools in clinical practice, like surgical guidance. 2 This challenge requires us to combine a high-speed OCT imaging setup, ultrafast data acquisition and adequate real-time data processing to process and visualize the vast amount of data. Although 4-D-OCT has long been a dream for researchers, only a few groups have successfully implemented 4-D volumetric OCT imaging with real-time visualization—usually with low ...

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    4. MR-OCT: Affordable Tomographic Imaging Applications

      MR-OCT: Affordable Tomographic Imaging Applications

      The application of optical coherence tomography (OCT) in the field of biomedical imaging has increased rapidly in recent years and may continue on this trajectory with growth potential in clinical diagnostics. 1 Integration of OCT for affordable point-of-care (POC) diagnostic applications and personal-care monitoring should lead to miniature, inexpensive, portable, robust optical instrumentation that is accurate and simple to use. However, the current embodiments of OCT systems are highly expensive, utilize large-form-factor optical design, and require accurate alignment of complex optics, making them impractical for the POC environment. In recent years, there has been an increasing interest in the development ...

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    5. Expanding OCT: Quanitifying the Cornea’s Optical Performance

      Expanding OCT: Quanitifying the Cornea’s Optical Performance

      Optical coherence tomography, a well-known method for imaging the retina, may allow physicians to perform quantitative metrology of the eye’s own optics. Swept-source OCT allows for simultaneous imaging of the cornea, iris and retina in living patients. Laser refractive surgeries such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) have brought better vision to tens of millions worldwide. But these techniques also exact a cost: because they work by reshaping the eye’s cornea, they make accurate measurement of the cornea’s optical parameters after surgery unreliable using conventional tools. That’s important, not only because inaccurate ...

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    6. U.S. Patent Reform and Photonics Companies

      U.S. Patent Reform and Photonics Companies

      A new law represents the most significant patent reform that the United States has seen in over 50 years. Joseph Gortych explains what optical entrepreneurs need to know about the America Invents Act. As those familiar with the patent process know, the U.S. Patent and Trademark Organization (USPTO) has until recently employed a “first-to-invent” system. That means that different inventors who filed patent applications on the same invention at different times could find themselves embroiled in an “interference proceeding” to determine who was first to invent and thus entitled to the patent. That changed on 16 March of this ...

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    7. Optics in 2012: The Best of the Best from Optics and Photonics News (VIDEO)

      Optics in 2012: The Best of the Best from Optics and Photonics News (VIDEO)

      This special issue of Optics & Photonics News highlights the most exciting peer-reviewed optics research to have emerged over the past 12 months. Our panel of editors reviewed close to 80 submitted summaries from scientists all over the globe. They selected for publication the 30 stories that they felt most clearly communicated breakthroughs of interest to the optics community.

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    8. U.S. Science Funding in Jeopardy

      U.S. Science Funding in Jeopardy

      The U.S. Office of Management and Budget (OMB) released a report in mid-September detailing the potential funding reductions of the automatic across-the-board $1.2 trillion spending cuts slated to go into effect 2 January 2013, barring an agreement in Congress on deficit reduction. The decreases were mandated under the Budget Control Act of 2011. The report was meant to encourage Congress to reach an agreement in 2012 on reducing the deficit, since the cuts will only go into effect if a deal is not made. To date, no legislation has been passed to prevent these reductions, which the OMB ...

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    9. OPN Talks with Dr. James Fujimoto - OCT Pioneer and CLEO:2011 Plenary Speaker

      OPN Talks with Dr. James Fujimoto - OCT Pioneer and CLEO:2011 Plenary Speaker
      Optical coherence tomography (OCT) is a relatively new technology, but is it having a significant impact in biomedical research. It was first demonstrated just 20 years ago, and it has already emerged as a powerful imaging tool in the biomedical world. In fact, OCT has become so widespread in the medical field that a journal keyword search on "optical coherence tomography" retrieves more than 10,000 references. The commercial market is estimated at several hundred million dollars. OPN recently caught up with James G. Fujimoto of the Massachusetts Institute of Technology, whose group and collaborators developed OCT. Fujimoto will deliver ...
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    1-9 of 9
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