1. 1-4 of 4
    1. Image analysis in optical coherence tomography Retinal layer segmentation (Thesis)

      Image analysis in optical coherence tomography Retinal layer segmentation (Thesis)

      How do we explain the world around us? Two wise men started the search for an answer thousands of years ago and became two of the most influential philosophers. Their debate still remains with us today. Plato believed true knowledge comes from the mind, which is rational, and not from the senses, which can be fooled. In contrast, Aristotle believed the senses allow us to learn and interact with the world around us. Despite this ongoing debate, we use our senses to experience the world around us. Of all our senses, the sense of sight contributes the most to our ...

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    2. Optimization-based adaptive optics for optical coherence tomography (Thesis)

      Optimization-based adaptive optics for optical coherence tomography (Thesis)

      Optical coherence tomography (OCT) is a technique for non-invasive imaging based on low coherence interferometry. Its main application is found in ophthalmology, where it is used for 3D in vivo imaging of the cornea and the retina. OCT has evolved over the past decade as one of the most important ancillary tests in ophthalmic practice, providing great diagnostic value for disease screening and monitoring. In retinal OCT imaging, the lateral resolution is not determined by the pupil size, but instead it is limited by optical wavefront aberrations of the cornea and lens. These aberrations reduce the OCT image resolution and ...

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    3. Development of a Retinal Eye Tracker for 3D Optical Coherence Tomography (Thesis)

      Development of a Retinal Eye Tracker for 3D Optical Coherence Tomography (Thesis)

      Several eye diseases appear in the posterior part of the eye, i.e. the retina or fundus. Retinal images therefore provide valuable information to identify eye diseases. Optical Coherence Tomography (OCT) is a 3D imaging technique that can image the retina with a resolution and depth penetration that can not be achieved by any other non-invasive imaging technique. Although OCT can achieve high resolution, in vivo measurements are severely limited by eye motion. TNO developed a low-cost eye tracker with improved eye motion tracking compared to current state of the art eye trackers. The eye tracker images the retina at ...

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    4. Optical Coherence Tomography for Material Characterization (Thesis)

      Optical Coherence Tomography for Material Characterization (Thesis)

      Optical coherence tomography (OCT) is a non-invasive, contactless and high resolution imaging method, which allows the reconstruction of two or three dimensional depth-resolved images in turbid media. In the past 20 years, OCT has been extensively developed in the field of biomedical diagnostics, while OCT in the non-destructive testing (NDT) field is lagging far behind. The aim of this thesis is to use OCT as a novel NDT technique for material structure characterization and damage detection. Besides an overview of the OCT fundamentals and developments, the thesis is mainly driven by three tasks: instrument design, signal processing, and applications. An ...

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    1-4 of 4
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