1. Articles from uspto.gov

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  2. 1-24 of 2070 1 2 3 4 ... 85 86 87 »
    1. Multichannel optical receivers

      Multichannel optical receivers

      Methods and apparatus are presented for multichannel optical coherence tomography. Light from a wavelength tuneable or steppable optical source is separated into one or more sample beams and one or more reference beams, and the one or more sample beams directed onto a sample to form one or more interaction regions. A plurality of returning probe beams are collected and mixed with the one or more reference beams to form an interference pattern comprising a plurality of interferograms having at least two distinct carrier frequencies. The multichannel optical apparatus can be provided with polarisation discrimination by mixing the returning probe ...

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      Mentions: Cylite
    2. System and method for characterizing tissue organization using polarization sensitive optical coherence tomography

      System and method for characterizing tissue organization using polarization sensitive optical coherence tomography

      Abstract A system and method for characterizing tissue organization using polarization sensitive optical coherence (PSOCT) tomography is provided. A PSOCT device is controlled, by a computing device, to obtain PSOCT A-line scans across a sample. For each of the PSOCT A-line scans, the computing device determines a frequency characteristic of any banding present in a respective PSOCT A-line retardance scan. The computing device controls display device to render a map of the frequency characteristic.

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    3. Guidewire detection systems, methods, and apparatuses

      Guidewire detection systems, methods, and apparatuses

      In part, the disclosure relates to methods of guidewire detection in intravascular data sets such as scan lines, frames, images and combinations thereof. Methods of generating one or more indicia of a guidewire in a representation of blood vessel are also features of the disclosure. A carpet view is generated in one embodiment and regions of relatively higher contrast are detected as candidate guidewire regions. In one embodiment, the disclosure relates to selective removal of guidewire segments from a set of intravascular data and the display of a representation of a blood vessel via a user interface. Representations of a ...

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      Mentions: Abbot
    4. Methods and systems for OCT guided glaucoma surgery

      Methods and systems for OCT guided glaucoma surgery

      Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured ...

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    5. Optical coherence tomography for orthodontic aligners

      Optical coherence tomography for orthodontic aligners

      Methods and apparatuses for 3D imaging (including 3D optical coherence tomography imaging) to measure the shape of orthodontic aligners, teeth, and other oral structures simultaneously, in-vivo or in-vitro. These methods and apparatuses may be used to determine contact locations of aligners with teeth and/or teeth with other teeth with very high precision, including determining the size of gaps where they are not in contact. These measurements may be used design, modify or replace an aligner and/or to verify aligner fit. 3D models of the whole aligner and teeth may be generated.

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    6. Optical imaging and measurement systems and methods for cataract surgery and treatment planning

      Optical imaging and measurement systems and methods for cataract surgery and treatment planning

      An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

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    7. Systems and methods for variable-range fourier domain imaging

      Systems and methods for variable-range fourier domain imaging

      An optical system includes a light source, an interferometer, and a detector. The interferometer includes a scanner and a lens system disposed downstream of the scanner. The scanner is configured to direct a portion of the optical beam along one of a plurality of different directions within a scanning range. The lens system is configured to project the portion of optical beam to an imaging area defined by a field of view of the optical system, the lens system comprising a first lens, wherein an aspect of the first lens is adjustable so as to render the field of view ...

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    8. Efficient sampling of optical coherence tomography data for explicit ranging over extended depth

      Efficient sampling of optical coherence tomography data for explicit ranging over extended depth

      An efficient OCT data collection and processing method for obtaining a high-axial-resolution image with explicit ranging over an extended depth is described. The method includes collecting a first dataset at a transverse location of the sample. The first dataset comprises spectra of a bandwidth (.DELTA.k.sub.1) sampled at a spectral sampling interval (dk.sub.1). A second dataset comprising spectra of a bandwidth (.DELTA.k.sub.2) sampled at a spectral sampling interval (dk.sub.2) is collected. The bandwidth .DELTA.k.sub.2 is less than .DELTA.k.sub.1 and spectral sampling interval dk.sub.2 ...

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    9. Methods, systems and apparatus for temporal calibration of an intravascular imaging system

      Methods, systems and apparatus for temporal calibration of an intravascular imaging system

      In part, the disclosure relates to systems for imaging a blood vessel using intravascular image data and extravascular image data and methods to calibrate such systems. In one embodiment, multiple calibration trials are performed to determine a plurality of time lag values. A minimum time lag value is used to align intravascular image data and extravascular time lag data in one embodiment.

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      Mentions: Desmond C. Adler
    10. Apparatus and methods for optical coherence tomography and two-photon luminescence imaging

      Apparatus and methods for optical coherence tomography and two-photon luminescence imaging

      Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.

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    11. Surface emitting laser, information obtaining apparatus, and imaging apparatus

      Surface emitting laser, information obtaining apparatus, and imaging apparatus

      The present invention provides a surface emitting laser the wavelength-tunable band of which is wide. The wavelength-tunable surface emitting laser includes a first reflector (101), an active layer (103) disposed on the first reflector (101), a beam portion (110) disposed over the active layer (103) with an air gap therebetween, and a second reflector (120) disposed on the beam portion (110). The second reflector (120) has a distributed Bragg reflector consisting of a stack of dielectric layers. The beam portion (110) has a distributed Bragg reflector consisting of a stack of conductive semiconductor layers.

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    12. Processing optical coherency tomography scans

      Processing optical coherency tomography scans

      A method of processing optical coherence tomography (OCT) scans through a subject's skin, the method comprising: receiving at least one OCT scan through the subject's skin, each scan representing an OCT signal in a slice through the subject's skin; processing each OCT scan so as to determine a set of parameters comprising at least a measure of the atrophy of the vascular structure in the epidermis; in which the processing produces a measurement of skin condition dependent upon each of the set of parameters, and the method comprises outputting the measurement of skin condition.

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    13. Method for signal processing in optical coherence tomography by means of a tunable light source

      Method for signal processing in optical coherence tomography by means of a tunable light source

      The invention relates to a method for signal processing in optical coherence tomography by means of a tunable light source (swept source), comprising the following steps: tuning the light source and sensing a signal intensity of the light source in linear dependence on the respective wave number (k) of the tunable light source and producing a signal intensity distribution in dependence on k; applying a window function to the sensed signal intensity distribution and producing a weighted signal intensity distribution; and applying a fast Fourier transform (FFT) to the weighted signal intensity distribution; and characterized in that, in the tuning ...

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    14. Frequency down conversion optical coherence tomography system and method

      Frequency down conversion optical coherence tomography system and method

      An optical coherence tomography (OCT) system for imaging a sample is provided. The OCT system includes an optical circuit and a digitization circuit. The optical circuit includes an interferometer and is configured to probe the sample and generate an analog OCT signal representative of the sample. The digitization circuit includes a frequency down converter and an analog-to-digital converter. The digitization circuit is configured to receive, down convert and digitize the analog OCT signal, thereby outputting a digitized down converted signal. A method for imaging a sample is also provided. The method includes steps of optically probing the sample to generate ...

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    15. Optical coherence tomography (OCT) system having integrated detector and analysis systems

      Optical coherence tomography (OCT) system having integrated detector and analysis systems

      An optical detector system comprises a hermetic optoelectronic package, an optical bench installed within the optoelectronic package, a balanced detector system installed on the optical bench. The balanced detector system includes at least two optical detectors that receive interference signals. An electronic amplifier system installed within the optoelectronic package amplifies an output of at least two optical detectors. Also disclosed is an integrated optical coherence tomography system. Embodiments are provided in which the amplifiers, typically transimpedance amplifiers, are closely integrated with the optical detectors that detect the interference signals from the interferometer. Further embodiments are provided in which the interferometer ...

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    16. Quantification of local circulation with OCT angiography

      Quantification of local circulation with OCT angiography

      Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for imaging microcirculation within different intraocular regions. A method to quantify SSADA results was developed and used to detect perfusion changes in early stage ocular disease. Associated embodiments relating to methods ...

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    17. System and method for imaging subsurface of specimen

      System and method for imaging subsurface of specimen

      There is a need for robust and portable system, apparatus and method for imaging subsurface of specimens. We have described a modular OCDR-OCT system and OFDR-OCT system to obtain high quality images. The instant application also discusses proprietary algorithms that have been modified from existing algorithms and their use as a combination to suit a particular system. The imaging of stationary, moving and combination of both subsurface structures such as retina for diabetic patients is described.

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    18. Apparatus and method for generating 3-D data for an anatomical target using optical fiber shape sensing

      Apparatus and method for generating 3-D data for an anatomical target using optical fiber shape sensing

      A fiber housing includes multiple shape sensing cores and a single optical core. A distal end of the fiber housing is positionable to direct the single optical core to a current point of an anatomical target. Collimated light over a first range of frequencies is projected from the single optical core to the current point. OFDR is used to detect reflected light scattered from the current point and to process the detected light to determine a distance to the current point. Light over a second range of frequencies is projected through the multiple shape sensing optical cores to the distal ...

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    19. Polarization sensitive optical coherence tomography using multiple polarization sensitive semiconductor optical amplifiers

      Polarization sensitive optical coherence tomography using multiple polarization sensitive semiconductor optical amplifiers

      This disclosure relates to an OCT apparatus configured to generate to electromagnetic (e.g., optical) signals having two different polarization states. Two or more silicon optical amplifiers (SOAs) can be configured to maintain a respective polarization state in an optical input signal provided from a light source (e.g., a broadband light source). The different polarization states can be combined by an optical combiner (e.g., a polarization maintaining fiber coupler) and provided to drive a reference arm and a sample arm implemented in an OCT system.

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    20. Speckle reduction in optical coherence tomography images

      Speckle reduction in optical coherence tomography images

      An optical coherence tomography (OCT) image composed of a plurality of A-scans of a structure is analyzed by defining, for each A-scan, a set of neighboring A-scans surrounding the A-slices scan. Following an optional de-noising step, the neighboring A-scans are aligned in the imaging direction, then a matrix X is formed from the aligned A-scans, and matrix completion is performed to obtain a reduced speckle noise image.

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    21. Jones matrix OCT system and program for carrying out image processing on measured data obtained by said OCT

      Jones matrix OCT system and program for carrying out image processing on measured data obtained by said OCT

      A Jones matrix OCT offers improved image stability, image quality, and depth range of image, wherein light from a wavelength-scanning light source is split into two optical paths, and a reference arm is provided along one optical path, while a probe arm that irradiates and reflects light onto the measuring target to generate object light is provided along the other optical path. The probe arm has a polarization delay unit that linearly polarizes the light and then splits it into S-wave component and P-wave component, where the S-wave component and P-wave component are superimposed through optical paths of different optical ...

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    22. Microscope having an optical coherence tomography device

      Microscope having an optical coherence tomography device

      A microscope having an observation beam path including a main objective, an OCT device including a first detection beam path, a wavefront measuring device including a second detection beam path, a first, a second and a third optics group is provided, wherein the first detection beam path contains the main objective and the first to third optics group, and the first to third optics group forms an afocal imaging optical unit of the first detection beam path and the second detection beam path contains the main objective, the first optics group and the second optics group, and the main objective ...

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    23. Automatic three-dimensional segmentation method for OCT and doppler OCT angiography

      Automatic three-dimensional segmentation method for OCT and doppler OCT angiography

      A three-dimensional (three dimensional) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source OCT. The automatic three dimensional segmentation method is used to obtain seven surfaces of intra-retinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers are visualized, and the morphology and contrast images can be improved by using the segmentation method. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases. Each tomographic image is composed of eight repeat scans at the same position ...

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    24. Method to characterize cut gemstones using optical coherence tomography

      Method to characterize cut gemstones using optical coherence tomography

      The invention includes an improvement in a method of assessing a gemstone having at least one planar face with an internally reflecting surface including the steps of optically modifying the at least one planar face of the gemstone to return a sample beam from an internally reflecting plane corresponding to the at least one planar face to an optical coherence tomography (OCT) system; selectively directing the sample beam from an optical coherence tomography (OCT) system onto the gemstone; and generating an OCT image map of the gemstone to determine volume, gem carat weight and/or quality.

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    1-24 of 2070 1 2 3 4 ... 85 86 87 »
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