1. Articles from uspto.gov

    patft.uspto.gov

  2. 1-24 of 2001 1 2 3 4 ... 82 83 84 »
    1. Optical coherence tomography (OCT) data processing method, storage medium storing program for executing the OCT data processing method, and processing device

      Optical coherence tomography (OCT) data processing method, storage medium storing program for executing the OCT data processing method, and processing device

      An Optical Coherence Tomography (OCT) data processing apparatus includes an acquisition unit configured to acquire three dimensional (3-D) OCT data of an object to be inspected, a generation unit configured to generate a motion contrast image based on the 3-D OCT data, and a detection unit configured to detect a inner surface coordinate of a vessel wall based on position information of an edge of a vessel region in the motion contrast image.

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    2. Systems and methods for quantitative assessment of microvasculature using optical coherence tomography angiography

      Systems and methods for quantitative assessment of microvasculature using optical coherence tomography angiography

      A five-index quantitative analysis of OCT angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of interest and generating a binary vasculature map from the vascular image data. A vessel skeleton map and vessel perimeter map are generated from the binary vasculature map. Based on the three generated maps, a vessel area density, vessel skeleton density, vessel perimeter index, vessel diameter index, and vessel complexity can be determined, in addition to detection of any flow impairment zones in the region of interest. These metrics can be ...

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    3. Systems and methods to compensate for reflectance variation in OCT angiography

      Systems and methods to compensate for reflectance variation in OCT angiography

      Methods and systems for improving quantification of OCT angiography data are disclosed. The disclosure specifically relates to methods for compensating for the effect of tissue reflectance to improve the accuracy and repeatability of OCT angiography measurements. These improvements are effected by deriving and then utilizing a dynamic thresholding approach to process decorrelation data to properly classify flow versus non-flow data in OCT angiograms. The disclosed methods overcome quantification errors associated with within-scan variations in reflectance as well as repeatability problems associated with differences in scan quality over successive imaging sessions.

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    4. Systems and methods for wide field-of-view optical coherence tomography

      Systems and methods for wide field-of-view optical coherence tomography

      An optical coherence tomography (OCT) system includes a light source configured to generate an OCT beam and a beam splitter, configured to split the OCT beam into a reference beam and an imaging beam, direct the reference beam toward a reflector, and direct the imaging beam toward a scanner. The system includes a linear actuator, such as a piezoelectric or voice coil, configured to move the reflector to adjust the length of the reference beam and the scanner, configured to scan the imaging beam onto a target surface at a plurality of scan angles, wherein the scanner and target surface ...

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    5. Post-processing reduction of fixed pattern artifacts and trigger jitter in swept-source optical coherence tomography

      Post-processing reduction of fixed pattern artifacts and trigger jitter in swept-source optical coherence tomography

      Disclosed herein are methods and systems for aligning swept-source optical coherence tomography (SS-OCT) spectral interferograms to a reference spectral interferogram based on signal information (e.g., amplitude or phase) at a fixed-pattern noise location to reduce residual fixed-pattern noise and improve the phase stability of SS-OCT systems.

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    6. Crosstalk elimination or mitigation in optical coherence tomography

      Crosstalk elimination or mitigation in optical coherence tomography

      One or more devices, systems, methods and storage mediums for performing optical coherence tomography (OCT) while reducing and/or eliminating crosstalk noise are provided. Examples of such applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Preferably, the OCT devices, systems methods and storage mediums include or involve a method, such as, but not limited to, a complex conjugate method or a ...

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    7. Step-scanning sensing beam for imaging interferometer

      Step-scanning sensing beam for imaging interferometer

      In interferometer imaging signal acquisition using a movable optical beam to sample a target with specular or non specular reflecting surfaces or internal features, beam moving during interferometer signal acquisition can generate unwanted phase error due to shifting speckle field. Examples include coherent LIDAR, Interferometry Doppler sensing and optical coherence tomography. During an interferometer signal acquisition period, an interferometer sensing beam can be substantially stationary, and active step-scanning can be synchronized with interferometer signal acquisition cycles. For interferometers using repetitive chirping lasers, passive dispersive counter-scan mechanisms can be used to assist step-scanning operation.

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    8. Optical coherence tomography apparatus and method using line confocal filtering

      Optical coherence tomography apparatus and method using line confocal filtering

      An optical tomography apparatus comprises: a polychromatic light source, a one-dimensional optical sensor, an interferometric microscope, a one-dimensional confocal spatial filtering system, an actuation system making it possible to perform a one-way scan depthwise of an object to be observed and a processor for reconstructing a two-dimensional image of a section of the object from a plurality of one-dimensional interferential images acquired by the image sensor during the one-way scan. An optical tomography method based on use of such an apparatus is also provided.

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    9. Detection of missampled interferograms in frequency domain OCT with a k-clock

      Detection of missampled interferograms in frequency domain OCT with a k-clock

      Optical coherence tomography light sources can be non-linear and attempts to linearize them can lead to asynchrony between the light source and A-line scans and missampling in the scans causing signal noise. Accordingly, a system and methods are provided herein to detect missampling by obtaining a plurality of interferograms; providing at least two wavenumber reference signals at different wavenumbers, wherein the wavenumber reference signals comprise attenuated or enhanced portions of each of the plurality of interferograms; aligning each of the plurality of interferograms according to one of the at least two wavenumber reference signals; and for each of the plurality ...

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    10. Systems and methods for quantitative doppler optical coherence tomography

      Systems and methods for quantitative doppler optical coherence tomography

      Methods of obtaining a measure of blood flow using a Fourier domain optical coherence tomography (FDOCT) system is provided. The method includes obtaining a first optical coherence tomography (OCT) survey scan of a retina of a subject using an OCT scan beam and obtaining a second OCT scan of the retina. The second OCT scan is within an area defined by the obtained first OCT scan and includes a region of retinal blood vessels emerging from and returning to an Optic Nerve Head (ONH) of the retina. An optical phase change is determined from the obtained second OCT scan, the ...

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    11. Subtractive en face optical coherence tomography imaging

      Subtractive en face optical coherence tomography imaging

      En face or 3D volumetric OCT imaging during ophthalmic surgery may be performed with an OCT scanning controller that interfaces to an OCT scanner used with a surgical microscope. The OCT scanner may generate en face images before and after surgical operations, such as retinal membrane peeling, are performed. Using digital subtraction on the en face images, an overlay image indicative of the changes from the surgical operations to the eye may be generated and overlaid onto an optical image displayed to a user of the surgical microscope.

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      Mentions: Lingfeng Yu
    12. System and method for providing surgical guidance based on polarization-sensitive optical coherence tomography

      System and method for providing surgical guidance based on polarization-sensitive optical coherence tomography

      Systems and methods are provided for identifying a suitable surgical location and/or trajectory for proceeding with a surgical procedure based on local polarization-sensitive optical coherence tomography imaging (PS-OCT). PS-OCT images are obtained of a tissue region and are processed to provide a spatial map of anisotropic structure within the tissue region. The anisotropic structure is processed to determine one or more suitable surgical locations and/or trajectories for avoiding or reducing damage to local anisotropic tissue structure identified within the tissue region. The spatial map of the anisotropic structure is registered with pre-operative volumetric image data identifying anisotropic tissue ...

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    13. Ophthalmologic information processing apparatus and ophthalmologic information processing method

      Ophthalmologic information processing apparatus and ophthalmologic information processing method

      An ophthalmologic information processing apparatus for performing follow-up of a subject eye based on plural pieces of OCT data obtained at different dates includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the ophthalmologic information processing apparatus to execute: a first acquisition process of acquiring plural pieces of layer thickness information regarding a fundus, the plural pieces of layer thickness information being a processing result of the plural pieces of OCT data of the subject eye; a matching process of matching the pieces of layer thickness information based on the plural pieces of OCT ...

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      Mentions: Nidek
    14. Method and system for three-dimensional imaging

      Method and system for three-dimensional imaging

      A method for three-dimensional imaging stores a first image of field of view from a handheld optical coherence tomography (OCT) scanning device at a first position where a first OCT scan of an object is captured with the scanning device freely operated by a user. A location metric of a second image of field of view of the scanning device is estimated at a second position relative to the first image while the scanning device is moved from the first to the second position. Instructions on providing user feedback are generated based on the location metric. Feedback is provided to ...

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    15. Method and system for optically evaluating drilling proximity to the inferior alveolar nerve in situ

      Method and system for optically evaluating drilling proximity to the inferior alveolar nerve in situ

      A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source for generating low coherence excitation light, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises a low coherence interferometry sub-system and a digital signal processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted ...

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    16. Method and apparatus for OCT-based viscometry

      Method and apparatus for OCT-based viscometry

      Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at a plurality of temporal delays. A cross-correlation function of at least one of amplitude, phase and intensity of a scattered optical field is derived for a plurality of depths relative ...

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    17. Methods and apparatus for retina blood vessel assessment with OCT angiography

      Methods and apparatus for retina blood vessel assessment with OCT angiography

      A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

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    18. Method and apparatus for measuring and displaying dental plaque, gingiva, and alveolar bone

      Method and apparatus for measuring and displaying dental plaque, gingiva, and alveolar bone

      A method and an apparatus for measuring and displaying dental plaque are provided, and the method includes the steps of dividing near infrared light output from a light source into measurement light and reference light, applying the measurement light toward a tooth in an oral cavity and scanning the tooth with the measurement light, producing interference light from reflected light and back-scattered light from the tooth and the reference light, generating an optical coherence tomographic image based on a scattering intensity value of the interference light, extracting a dental plaque region having a specific scattering intensity value from the optical ...

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    19. Image processing apparatus, estimation method, system, and medium

      Image processing apparatus, estimation method, system, and medium

      The position of the fovea is estimated with high accuracy in a manner such that the thicknesses of a first region including at least a partial region of a region from the internal limiting membrane to the boundary between the external plexiform layer and the external granular layer and a second region including at least a partial region of a region from the boundary to the photoreceptor cell inner segment/outer segment junction are compared with each other, and the position of the fovea is estimated.

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    20. Supercontinuum light source comprising microstructured optical fiber

      Supercontinuum light source comprising microstructured optical fiber

      The invention relates to a microstructured optical fiber for generating supercontinuum light upon feeding of pump light. The light can be incoherent light. The microstructured optical fiber has a first section and a second section, where the first and second sections have one or more different features. The invention also relates to a supercontinuum source comprising a microstructured optical fiber according to the invention.

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      Mentions: NKT Photonics
    21. Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Disclosed herein are methods and systems for the identification and characterization of fluid accumulation in the retina using OCT imaging. The disclosed methods and systems are directed to the automated segmentation of retinal fluid using 2D or 3D structural OCT scan images. Approaches for visualization and quantification of both intraretinal and subretinal fluid are presented. Methods are also disclosed for using OCT angiography data to improve the quality of retinal fluid segmentation, and to provide combined visualization of fluid accumulation and retinal vasculature to inform clinical interpretation of results.

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    22. System and method for dynamic focus control

      System and method for dynamic focus control

      En face views of OCT volumes provide important and complementing visualizations of the retina and optic nerve head investigating biomarkers of diseases affecting the retina. We demonstrate the combination of real time processing of OCT volumetric data for axial tracking. In combination with a Controllable Optical Element (COE), this invention demonstrates acquisition, real time tracking, automated focus on depth resolved en face layers extracted from a volume, and focus stacked OCT volumes with high resolution throughout an extended depth range.

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    23. Optical coherence tomography for measurement on the retina

      Optical coherence tomography for measurement on the retina

      An optical coherence tomograph that provides wavelength tunable source radiation and an illumination and measurement beam path, a dividing element that divides source radiation into illumination radiation and reference radiation, and collects measurement radiation. The illumination and measurement beam path has scanner. A detection beam path receives measurement radiation and reference radiation and conducts them onto at least one flat panel detector in a superposed manner. A beam splitter separates the measurement radiation from the illumination radiation. The beam splitter conducts the separated measurement radiation to the detection beam path and sets the numerical aperture of the illumination of the ...

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    24. Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

      Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

      Exemplary apparatus and method can be provided for obtaining data regarding a plurality of samples. For example, using at least one arrangement, it is possible to receive interferometric information that is based on radiations provided from a reference and the samples that are provided in respective chambers. Alternatively and/or in addition, based on the interferometric information, it is possible to discriminate between agents to identify a particular agent that affects a particular function within at least one of the samples.

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    1-24 of 2001 1 2 3 4 ... 82 83 84 »
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