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    1. Imaging the adult zebrafish cone mosaic using optical coherence tomography

      Imaging the adult zebrafish cone mosaic using optical coherence tomography

      Zebrafish ( Danio rerio ) provide many advantages as a model organism for studying ocular disease and development, and there is great interest in the ability to non-invasively assess their photoreceptor mosaic. Despite recent applications of scanning light ophthalmoscopy, fundus photography, and gonioscopy to in vivo imaging of the adult zebrafish eye, current techniques either lack accurate scaling information (limiting quantitative analyses) or require euthanizing the fish (precluding longitudinal analyses). Here we describe improved methods for imaging the adult zebrafish retina using spectral domain optical coherence tomography (OCT). Transgenic fli1:eGFP zebrafish were imaged using the Bioptigen Envisu R2200 broadband source OCT ...

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    2. Optical Coherence Tomography in Neurologic Diseases (Textbook)

      Optical Coherence Tomography in Neurologic Diseases (Textbook)

      Optical coherence tomography [OCT] provides tissue morphology imagery at much higher resolution than other imaging modalities such as MRI or ultrasound, and the machines are comparatively cheaper. It is an easy technique to perform; is non-ionizing, and therefore safe. These benefits are driving a rapid transformation of OCT, from its principal application as a research tool, into an extension of the 'neurological examination' in routine office practice. Originally used in assessing the severity of tissue damage and prognosis of multiple sclerosis and various neuro-ophthalmic conditions, OCT is increasingly used in other neurological disorders such as Parkinson's disease, ALS, and ...

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    3. Gastric Cancer (Book)

      Gastric Cancer (Book)
      Gastric adenocarcinoma is the second most common cancer worldwide. It is usually diagnosed at a late stage and prognosis is poor; even with modern diagnostic and treatment methods the 5-year survival is only 10%. Improvements in overall patient survival can only be achieved by earlier diagnosis and by tailored therapeutic strategies based on tumor type, location and stage at presentation. This volume provides a state-of-the-art, integrated diagnostic and therapeutic approach to patient management. The role of the upper GI series, endoscopy, endoscopic ultrasound, MDCT, MRI, and PET/CT in the diagnosis, staging and follow-up of patients with gastric cancer is ...
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