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    1. OCT Vs FFR: Which Is the Better Guide for Revascularization?

      OCT Vs FFR: Which Is the Better Guide for Revascularization?

      Optical coherence tomography goes up against physiological guidance in angiographically intermediate coronary lesions MedpageToday by Nicole Lou, Contributing Writer, MedPage Today September 30, 2019 This article is a collaboration between MedPage Today® and: SAN FRANCISCO -- Optical coherence tomography (OCT) was associated with fewer events down the line for percutaneous coronary intervention (PCI) candidates presenting with intermediate coronary lesions on angiography, the FORZA investigators found. The 13-month primary endpoint of combined major adverse cardiac events (MACE) or significant angina -- comprising all-cause death, non-fatal MI, target vessel revascularization, or Seattle Angina Questionnaire frequency scale score <90 -- was significantly more common after fractional ...

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    2. Are the Eyes Windows to Early Dementia? Thinner retinal nerve fiber layer may be associated with worse cognitive function

      Are the Eyes Windows to Early Dementia? Thinner retinal nerve fiber layer may be associated with worse cognitive function

      Retinal neurodegeneration was linked to cognitive decline, adding to a growing literature that suggests retinal structures may be biomarkers for dementia, according to results from two prospective studies. A thinner retinal nerve fiber layer (RNFL) was tied to worse cognitive function in people without neurodegenerative disease and greater odds of future cognitive decline, reported Paul Foster, PhD, of the University College London, and colleagues, for the U.K. Biobank Eye & Vision Consortium . And among Rotterdam Study participants in the Netherlands, thinner RNFL was associated with increased risk of dementia, including Alzheimer's disease, according to M. Kamran Ikram, MD, PhD ...

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    3. Early, Late Stent Thrombosis Look Different on OCT

      Early, Late Stent Thrombosis Look Different on OCT

      The mechanism behind coronary stent thrombosis may vary depending on the stent type and whether it occurs early or later on, images from optical coherence tomography (OCT) suggested. Overall, stent underexpansion (stent expansion index <0.8) was observed in 44.4% of patients who presented with stent thrombosis in the PRESTIGE registry, Robert Byrne, MB BCh, PhD, of Germany's Deutsches Herzzentrum München, and colleagues reported in Circulation .

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    4. IVUS Guidance for Complex Lesion Stenting Tied to Fewer MIs (CME/CE)

      IVUS Guidance for Complex Lesion Stenting Tied to Fewer MIs (CME/CE)

      To guide implantation of newer-generation drug-eluting stents (DES) in complex lesions, intravascular ultrasound (IVUS) beat angiography for reduced rates of subsequent MI, according to a meta-analysis. One year after stenting, major adverse cardiovascular events -- the composite of cardiac death, MI, and stent thrombosis -- had occurred in 0.4% of IVUS-guided DES recipients and 1.2% of their peers who underwent angiography-guided DES placement (HR 0.36, 95% CI 0.13-0.99), according to Myeong-Ki Hong, MD, PhD , of Korea's Yonsei University College of Medicine, and colleagues. "These findings were consistent across the clinical (lesion/patient) subgroups and were stronger ...

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    5. Guidance Issued for Diagnostic Cath Lab Tools

      Guidance Issued for Diagnostic Cath Lab Tools

      Fractional flow reserve, intravascular ultrasound, and optical coherence tomography all likely have a place in the interventional cardiologist's armamentarium, according to a consensus statement from the Society for Cardiovascular Angiography and Interventions (SCAI). "Fractional flow reserve (FFR) is used to determine the functional significance of a coronary stenosis. Intravascular ultrasound (IVUS) offers excellent visualization of intraluminal and transmural coronary anatomy. Optical coherence tomography (OCT) further improves vascular visualization," stated the guidance, which was published online in Catheterization and Cardiovascular Interventions . ..

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    6. Optical Imaging Safe, Helpful in Carotid Stenting

      Optical Imaging Safe, Helpful in Carotid Stenting

      Intravascular optical coherence tomography (OCT) proved safe, feasible, and capable of providing high-quality images in patients undergoing protected carotid artery stenting, results of a small clinical study showed. Reviews by two independent readers resulted in an average image quality score of 8.1 on a scale of 10. No procedural or in-hospital adverse events occurred in the 25 patients evaluated.

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    7. Party 'Popper' Drugs Damage Eyes

      Party 'Popper' Drugs Damage Eyes
      Experimenting with "poppers" -- inhaled alkyl nitrates used as recreational drugs -- can cause lasting retinal damage, ophthalmologists warned. Four cases over a three-month period in France were reported in a letter to the editors appearing in the Oct. 14 issue of the New England Journal of Medicine. The prolonged visual loss likely resulted from damage to foveal photoreceptors by the acute, massive release of nitric oxide from the drugs, Michel Paques, MD, PhD, of the Quinze-Vingts Hospital in Paris, and colleagues wrote. Poppers' popularity at parties and clubs for the intoxication and enhancement of sexual pleasure they produce has gone unopposed ...
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      Mentions: Michel Pâques
    8. Vision Compromised in Multiple Sclerosis Even Without Symptoms

      "The emergence of optical coherence tomography has allowed us to capture the unique structure-function correlations provided by the anterior visual pathway in multiple sclerosis," Dr. Bisker said in a presentation at the Association for Research in Vision and Ophthalmology.
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    1-9 of 9
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