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    1. Vascular imaging leader Volcano acquires IVUS developer Novelis

      May 23, 2008 -- Volcano Corp., provider of intravascular ultrasound (IVUS), functional measurement (FM) and Optical Coherence Tomography (OCT) products designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, has acquired Novelis. Novelis is known for its ultrasonic visualization and therapy technology for minimally invasive diagnostic and therapeutic devices.
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    2. OCT IP landscape more complicated than it looks

      In February 2008, the publishers of BioOptics World and Laser Focus World magazines published the first market research report to quantify the rapidly growing market for optical coherence tomography (OCT) technologies and applications (see www.laserfocusworld.com/articles/318570). Among other things, the report accurately describes the rather complex patent situation in the OCT market:
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    3. What if there were a genie in your microscope?

      What if there were a genie in your microscope?
      My eyes sweep across a lab rat and I can see everything. Images zoom in and out just because my brain starts thinking of looking at different scales. As my eyes pan along the length of the animal, I watch the trafficking of specific biochemicals, and I know which was which—all without labels, even without any apparent device at all.
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    4. Supercontinuum lasers begin to shine in biomedicine

      Supercontinuum lasers begin to shine in biomedicine
      Optical supercontinuum lasers produce light across a broad spectrum in high-power, ultrafast pulses. Originally developed by researchers seeking devices with high power and high speed, they soon found application beyond the lab in metrology, military affairs, and homeland security. Now they have begun to show promise in another field: biomedicine. Recent studies have revealed the lasers’ potential use in flow cytometry, confocal microscopy, and optical coherence tomography, among other areas. Vl
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    5. Microendoscopy takes a practical turn

      Microendoscopy takes a practical turn
      Discussions about how to motivate the medical community to embrace new technologies often focus on form and function—user-friendliness, compactness, ergonomics, speed, cost, and so on. For biomedical optics, these discussions further require demonstrating that a laser-based device can do something more-conventional approaches cannot, or at least do it better (such as laser refractive surgery, skin rejuvenation, hair removal, and optical coherence tomography). But with the advent of more-collabor
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    6. Ultrafast lasers advance deep-tissue imaging

      Ultrafast lasers advance deep-tissue imaging
      Since the first landmark two-photon microscopy images in 1990, a wide range of nonlinear imaging methods that utilize ultrafast lasers have evolved, including three-photon fluorescence excitation, second- and third-harmonic generation (THG), coherent anti-Stokes Raman spectroscopy (CARS), and other types of nonlinear optical effects.1 Two advantages of multiphoton microscopy are its inherent ability to provide high-resolution three-dimensional images at significant depths and to do this in live
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    7. Spectral-domain OCT wows interventional cardiologists

      A live demonstration of a next-generation optical coherence tomography (OCT) system from LightLab Imaging (Westford, MA) drew rave reviews from a crowd of more than 1000 interventional cardiologists attending the Transcatheter Cardiovascular Therapeutics (TFT) conference in Washington D.C. last October. Performed in Germany by Prof. Dr. Eberhard Grube of the Helios Heart Center (Siegburg, Germany) and beamed live to the main hall of the Washington Convention Center, the procedure provided real-time OCT images of a recently implanted stent and the tissues covering the stent struts with a resolution of 15 to 20 µm—more than 10 times the resolution ...
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    8. Michelson Diagnostics Announces Upgraded OCT Product

      Michelson Diagnostics Announces Upgraded OCT Product
      Michelson Diagnostics (Kent, UK) has released upgrades to the EX1301 OCT microscope. The upgrades provide higher imaging resolution, 3D image capture capability, and improved capture frame rate. The EX1301 is now available with the Santec-2000-W wide sweep laser, which provides an increase in the sweep range from 100 nm to 150 nm. The result is improved axial resolution and isotropic pixel size reduced from 6 mm to 4.5 mm (in tissue). 3D image capture is possible with the motorized stage option, enabling researchers to analyze 3D datasets and produce en-face images and 3D rendered graphical models of their samples ...
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    9. Inexpensive OCT glaucoma assessment tool can track MS activity

      January 16, 2008, Buffalo, NY--New research by neurologists at the University at Buffalo has shown that optical coherence tomography (OCT) also could be used as a surrogate marker of disease status in multiple sclerosis (MS) and to assess the effectiveness of new and current MS treatments.
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    10. The ultimate risk

      Any new venture carries with it a certain amount of risk. In this day and age we try to minimize that risk through business models, focus groups, market research, and the like. But I like to think there is still a place for gut instinct and intuition. Look at optical coherence tomography (OCT). Back in the early ’90s, when OCT was just another lab-based experiment in ultrafast technology, who could have imagined that it would one day become the first truly successful commercial application of op
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    11. Imaging technologies take charge in the war on cancer

      Quantitative spectroscopy, elastic light scattering, optical frequency-domain imaging, in vivo fluorescent imaging, vibrational microspectroscopy—these and similar optical techniques have made molecular imaging the fastest-growing approach to understanding and diagnosing cancers today. Researchers in biomedicine and physical science highlighted their efforts last November at Optical Imaging for Medicine and Biology: Applications in Cancer Detection, a one-day seminar hosted by Boston University’
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    12. Volcano sets sights on OCT market with CardioSpectra

      Ophthalmology has been the dominant commercial application for optical coherence tomography (OCT) for the past decade, but Volcano (San Diego, CA), a leading provider of intravascular-ultrasound (IVUS) and functional-measurement products for diagnosing and treating vascular and structural heart disease, is looking to change that with the addition of Fourier-domain OCT to its product-development portfolio. The company announced in mid-December that it would pay $25 million cash to acquire CardioS
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    13. James Fujimoto

      James Fujimoto
      Back in the 1980s, when he was a graduate student in Erich Ippen’s lab at the Massachusetts Institute of Technology (MIT; Cambridge, MA), spent many of his days (and often late nights) studying the effects of ultrafast lasers on semiconductors and organic materials. Little did he know that his research would come to serve as the foundation for one of the most important developments in biomedical optics in the past two decades—optical coherence tomography (OCT). “At the time, much
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    14. CardioSpectra gets boost in OCT development from Volcano

      December 11, 2007, San Diego, CA--Volcano Corporation , a provider of intravascular ultrasound (IVUS) and functional measurement (FM) products designed to enhance the diagnosis and treatment of vascular and structural heart disease, will acquire CardioSpectra (San Antonio, TX), a privately held company developing innovative optical coherence tomography (OCT) technology.
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