1. 1-6 of 6
    1. Bimodal probe images atherosclerotic plaque

      Bimodal probe images atherosclerotic plaque

      Atherosclerosis is a chronic disease in which artery walls thicken and harden through the accumulation of white blood cells and lipids, forming a plaque. Unstable or "vulnerable" plaques have the potential to rupture, generating dangerous blood clots. "Plaques rich in lipids, or with large lipid pools and a thin fibrotic cap are more likely to rupture," explains paper author Laura Marcu , a biomedical engineer at the University of California Davis. "Sudden plaque rupture can result in acute cardiovascular events, and potentially death." Traditionally, two modalities are used for in vivo imaging of atherosclerotic plaques: intravascular optical coherence tomography (OCT), which ...

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    2. Tethered capsule detects GI tract disease

      Tethered capsule detects GI tract disease

      The diagnosis and subsequent treatment of many diseases of the upper gastrointestinal tract often call for endoscopic examination. Unfortunately, this is typically expensive, uncomfortable, requires patient sedation and only provides limited information on surface tissues. Subsequent biopsies can provide additional information, but only from limited sample sites. This can be especially problematic when attempting to diagnose diseases with patchy presentations, such as Barrett's oesophagus – in which oesophageal tissues change to resemble those that line the intestine.

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    3. OCT helps identify cancerous brain tissue

      OCT helps identify cancerous brain tissue

      A brain cancer diagnosis can represent a death sentence, with remaining life measured in months to a year or so. Neurosurgery can increase the predicted survival time by up to 200%, depending upon the amount of tumour that can be resected. Distinguishing cancerous tissue from healthy brain tissue can be difficult, however, especially when it has infiltrated white matter. Current imaging detection technologies are suboptimal. Optical coherence tomography (OCT) offers the potential to identify cancerous brain tissue during surgery in an efficient and cost-effective manner. OCT can provide high-resolution volumetric imaging to a millimetre depth and deliver continuous, quantitative feedback ...

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    4. OCT mapping tracks skin cancer during PDT

      OCT mapping tracks skin cancer during PDT
      OCT mapping tracks skin cancer during PDT A case study at University College Hospital London has demonstrated the successful use of optical coherence tomography (OCT) for in vivo mapping of non-melanoma skin cancer during photodynamic therapy (PDT). PDT provides a non-invasive alterative to surgical excision for non-melanoma skin cancers. But as no tissue is removed for analysis, it can be difficult to ensure all the tumour is treated. This work showed that the use of OCT (the VivoSight from Michelson Diagnostics) to image skin before, during and after PDT, could solve this problem (Photodiagnosis and Photodynamic Therapy 8 49).
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    5. OCT market set for rapid growth

      The optical coherence tomography (OCT) market looks poised for continued growth, with revenues expected to top $800 million by 2012. That's the conclusion of a new market research report, Optical Coherence Tomography - Technology, Markets and Applications: 2008-2012. The report, published by US media company PennWell (Tulsa, OK), estimates that the global market for OCT systems currently stands at around $200 million and is growing at an annual rate of 34%. OCT is a non-invasive optical imaging
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    1-6 of 6
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