1. 169-184 of 184 « 1 2 3 4 5 6 7 8
    1. Early Coverage and Vessel Wall Response of the Zotarolimus Drug-Eluting Stent Implanted in AMI Assessed by Optical Coherence Tomography (OCTAMI)

      The objective of this study is to evaluate the completeness of struts coverage and vessel wall response (strut malapposition, neointima disomogeneities in texture) to the ENDEAVOR drug-eluting stent vs the DRIVER stent (bare metal stent of identical metallic platform) implanted for the treatment of the culprit lesion in ST-elevation acute myocardial infarction (STEMI). To investigate the completeness of the coverage as well as the number of uncovered stent struts per section (embedded, uncovered, malapposed) and the neointima texture, high resolution (~ 10-15 ┬Ám axial) intracoronary optical coherence tomography (OCT)will be used
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    2. Coherence Tomography Following Paclitaxel Eluting Stent Implantation in Multivessel Coronary Artery Disease (OCTAXUS)

      A prospective Optical Coherence Tomography (OCT) study on the completeness of strut coverage and vessel wall response, at different time points (3-6-9 Months), following TAXUS Liberte stent implantation (staged procedures) in patients with multi vessel native coronary artery lesions. Major concerns were addressed to the delayed healing process of drug-eluting stents in off-label indications. To date no studies have detailed the in-vivo completeness of DES coverage at different time points. The objective of this prospective study is to measure the completeness of strut coverage and vessel wall response (neointima disomogeneity, acquired late incomplete strut apposition) at different time points following ...
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    3. Optical Coherence Tomography for Drug Eluting Stent Safety (ODESSA)

      Increasing lesion complexity in percutaneous coronary interventions (PCI) has warranted the use of overlapping drug-eluting stents. Whether the substantial impairment of arterial healing observed at sites of overlap in preclinical pathologic studies persists in patients undergoing PCI is unknown. Consecutive patients with long lesions in native coronary vessels requiring stents in overlap are prospectively randomized to receive multiple sirolimus-,paclitaxel polymer-or zotarolimus eluting stents
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    4. Correlation Between Visual Field Defects on Foresee PHP and on Optical Coherence Tomography (OCT) in Eyes of Patients With Choroidal Neovascularization (CNV)

      The Foresee PHP is used in the recent years to detect Age-related Macular Degeneration (AMD) lesions. The device is capable of differentiation as to stages of AMD and early detection of changes including choroidal neovascularization (CNV) The Foresee PHP™ demonstrates a high level of sensitivity and specificity as to the different stages of AMD including newly diagnosed or early detection of CNV. The OCT May be use as well to identify choroidal neovascularization (CNV). Comparisson between the two methods will allow better understanding of both devices. The Foresee PHP can use as an assessment tool for the progression and success ...

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      Mentions: Notal Vision
    5. AREDS 2 Ancillary Spectral Domain Optical Coherence Tomography Study (A2ASDOCT)

      The purpose of this study is to identify whether changes in age-related macular degeneration (AMD) over time as seen with spectral domain optical coherence tomography (SDOCT) imaging, can be used to predict vision loss and the advancement of AMD in people at moderate to high risk for progression.
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    6. Agreement Between Spectral Domain and Time Domain Optical Coherence Tomography (OCT)

      Optical coherence tomography (OCT) is a well-established and safe technique that offers the possibility of visualizing retinal structure and measuring retinal thickness. Time-domain (TD)OCT is considered the "gold standard" technique for retinal thickness measurements. Spectral-domain (SD) OCT has to face the gold standard technique prior to obtain scientific and clinical consensus. In our study in healthy subjects foveal thickness will be measured with both TD and SD OCT , and the data will be compared to evidence any difference between the two retinal measurements techniques.
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    7. Reproducibility of Cirrus Optical Coherence Tomography Measurements

      In this study the reproducibility of optical coherence tomography measurements should be evaluated. Study Type: Observational Study Design: Cohort, Prospective Official Title: Reproducibility of Retinal Thickness and Volume Measurements Determined With the Cirrus Spectral Domain OCT Estimated Enrollment: 18 years of age or older best corrected visual acuity of at least 20/25 clear optical media any kind of retinal pathology any kind of opacity of optical media any kind of intraocular surgery sph
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    8. Comparison of Skin Thickness Under Treatment With Pimecrolimus 1% Cream, Hydrocortisonacetat 1% Cream, Betamethasonvalerat 0,1% Cream and Clobetasol-17-Propionat 0,05% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHZ Ultrasound

      Inclusion Criteria: male and female probands age between 18-40 years skin healthy skintype I-III according to Fitzpatrick Exclusion Criteria: women of childbearing potential without adequate contraception pregnant or breastfeeding genetic defect of epidermal barrier external or systemic treatment with drugs, which probably have an effect to the thickness of skin or to the production of teleangiektasien within the last 6 month before study entry skin disease, which hinder the evaluation with OCT, ultrasound or dermaphot UV treatment within the last 4 weeks before study entry participation to another clinical trial within the last 30 days before study entry allergy against ...
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    9. Optical Coherence Tomography of Airway and Pleural Disorders

      Optical methods for obtaining images in airway passages for early detection of endobronchial lung and pleural cancer are needed. Optical coherence tomography (OCT) is a non-invasive or minimally invasive diagnostic technique that can provide information about tissue abnormalities. OCT can produce images of abnormalities both at and below the surface of the airways without damaging the tissue surface This technique uses a harmless device to emit infrared (not visible) light that can produce images of the specimen under investigation without causing damage or alterations
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    10. OCT for Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer

      Optical coherence tomography (OCT) is a non-invasive diagnostic technique that can provide information about tissue abnormalities. This technique uses a near-infrared diode to emit light that can produce images of the specimen under investigation without causing damage or alterations. The research' want to compare the OCT results with that obtained from conventional histologic examination and to show that the OCT results may be almost as accurate as the standard Pathology results. Optical coherence tomography (OCT) is a new technique being developed that can be used for visualizing human tissue. OCT offers a means of providing information on the characteristics and ...
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    11. Corneal and Anterior Segment Optical Coherence Tomography - Optovue (CAS-OCT)

      Device: OCT measurements Two OCT systems from Optovue Inc. (Fremont, CA) are used to perform preoperative scanning. The first OCT system is called RTVue. It is a FDA-approved Fourier-Domain OCT system. The second OCT sytem is call ACVue. It is an experimental Time-Domain OCT system and used to measure crystalline lens thickness and anterior chamber depth. The measurements from both OCT systems are used in selecting IOL power.
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    12. Optical Coherence Tomography (OCT) Imaging of Post Coil Aneurysm Healing.

      At Beckman Laser Institute, University of California, Irvine, we have developed diagnostic device call 'Optical Coherence tomography (OCT).' OCT is an imaging technique capable of performing high-resolution,cross-sectional imaging. OCT enables real-time, in situ visualization of tissue microstructure without the need to excise and process the specimen as required for conventional biopsy and histopathology. OCT is analogous to ultrasound except that imaging is performed with light instead of acoustic waves. OCT measures light reflected from turbid structures. Consequently, OCT is a powerful method to image biological tissue in-vivo at high resolution. The objective of the study is to demonstrate a ...
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    13. An Exploratory Study on Optical Assessment of Oral Mucositis

      Optical coherence tomography (OCT) works similarly to ultrasound but uses infrared light waves rather than sound waves to create high-resolution pictures. This tool has been approved by the Food & Drug Administration (FDA), is used routinely for standard diagnosis of eye conditions, and is now being used to look inside your mouth for tissue changes. For the OCT procedure, a small probe, about the size of a pencil eraser, will be gently placed against the lining of your mouth and light will be shone through the probe to create pictures of the tissue. The probe will be placed on 1-2 abnormal-looking ...
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    14. Investigate the Diagnostic Value and Possibilities of OCT in Non-Melanoma Skin Cancer

      We will do systematic and functional assessment of non-melanoma skin cancer including precancerous lesions by OCT imaging and other diagnostic methods. The systematic assessment will be comparison of clinical diagnosis, histopathology, OCT images, spectrophotometry and high frequency ultrasound of non-melanoma skin cancer Functional exploration of non-melanoma skin cancer is done with Doppler-OCT and polarization-sensitive-OCT.
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    15. Novel Diagnostics With Optical Coherence Tomography: Retinal Imaging

      The purpose of this research is to evaluate optical coherence tomography (OCT) and FDA approved device used to image diseases of the eye. The ultra-high resolution OCT is a non-significant risk device used in this study. Optical Coherence Tomography may be useful for early diagnosis and monitoring of different types of eye diseases.
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    16. Optical Coherence Tomography of the Gastrointestinal Tract (OCT)

      Optical coherence tomography (OCT) is a non-invasive imaging technique that uses light to create pictures of living tissues and has been successfully used to generate high resolution cross-sectional images of tissue in the human eye and skin. OCT systems are now commercially available for eye and skin use, and several clinical reports on the use of OCT in the gastrointestinal tract have been published as well. The purpose of this study is to develop a high-speed noninvasive OCT probe which can be placed through an endoscope for the early diagnosis of pre-cancerous and cancerous lesions in the gastrointestinal tract. This ...
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    169-184 of 184 « 1 2 3 4 5 6 7 8
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