1. 1-10 of 10
    1. Retinal Blood Vessel Caliber Estimation for Optical Coherence Tomography Angiography Images Based on 3D Superellipsoid Modeling

      Retinal Blood Vessel Caliber Estimation for Optical Coherence Tomography Angiography Images Based on 3D Superellipsoid Modeling

      Changes of retinal blood vessel calibers may reflect various retinal diseases and even several non-retinal diseases. We propose a new method to estimate retinal vessel calibers from 3D optical coherence tomography angiography (OCTA) images based on 3D modeling using superellipsoids. Taking advantage of 3D visualization of the retinal tissue microstructures in vivo provided by OCTA, our method can detect retinal blood vessels precisely, estimate their calibers reliably, and show the relative flow speed visually.

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    2. Swept-Source Optical Coherence Tomography A Color Atlas 2nd Edition (Textbook)

      Swept-Source Optical Coherence Tomography A Color Atlas 2nd Edition (Textbook)

      This book is written for retinal specialists and clinicians with a special interest in retinal diseases. It presents a collection of images and brief annotations of the microstructures of both the normal and diseased eye captured on swept source optical coherence tomography. The swept-source OCT is a relatively new form of imaging and is able to capture structures and details which previous generations of OCT machines cannot. This type of imaging represents the forefront in ocular imaging. This second edition includes a new chapter on optic nerve conditions and more cases on eye conditions that were imaged with the SS-OCT ...

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    3. Swept-Source Optical Coherence Tomography A Color Atlas (Textbook)

      Swept-Source Optical Coherence Tomography A Color Atlas  (Textbook)

      This book is written for retinal specialists and clinicians with a special interest in retinal diseases. It presents a collection of images and brief annotations of the microstructures of both the normal and diseased eye captured on swept source optical coherence tomography. The swept-source OCT is a relatively new form of imaging and is able to capture structures and details which previous generations of OCT machines cannot. This type of imaging represents the forefront in ocular imaging.

      Read Full Article
    4. Swept-source Optical Coherence Tomography : A Color Atlas (Textbook)

      Swept-source Optical Coherence Tomography : A Color Atlas (Textbook)

      This book is written for retinal specialists and clinicians with a special interest in retinal diseases. It presents a collection of images and brief annotations of the microstructures of both the normal and diseased eye captured on swept source optical coherence tomography. The swept-source OCT is a relatively new form of imaging and is able to capture structures and details which previous generations of OCT machines cannot. This type of imaging represents the forefront in ocular imaging.

      Read Full Article
    5. Geographic mapping of choroidal thickness in myopic eyes using 1050-nm spectral domain optical coherence tomography Read More: http://www.worldscientific.com/doi/10.1142/S1793545815500121

      Geographic mapping of choroidal thickness in myopic eyes using 1050-nm spectral domain optical coherence tomography   Read More: http://www.worldscientific.com/doi/10.1142/S1793545815500121

      Purpose: To provide a geographical map of choroidal thickness (CT) around the macular region among subjects with low, moderate and high myopia. Methods: 20 myopic subjects (n = 40 eyes) without other identified pathologies participated in this study: 20 eyes of ≤ 3 diopters (D) (low myopic), 10 eyes between -3 and -6D (moderate myopic), and 10 eyes of ≥ 6D (high myopic). The mean age of subjects was 30.2 years (± 7.6 years; range, 24 to 46 years). A 1050 nm spectral-domain optical coherence tomography (SD-OCT) system, operating at 120 kHz imaging rate, was used in this study to simultaneously capture ...

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    6. Medical images classication for skin cancer using quantitative image features with optical coherence tomography

      Medical images classication for skin cancer using quantitative image features with optical coherence tomography

      Optical coherence tomography (OCT) is employed in the diagnosis of skin cancer. Particularly, quantitative image features extracted from OCT images might be used as indicators to classify the skin tumors. In the present paper, we investigated intensity-based, texture-based and fractal-based features for automatically classifying the melanomas, basal cell carcinomas and pigment nevi. Generalized estimating equations were used to test for differences between the skin tumors. A modified p value of < 0.001 was considered statistically significant. Significant increase of mean and median of intensity and significant decrease of mean and median of absolute gradient were observed in basal cell carcinomas ...

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    7. Virtual-OCT: A simulated optical coherence tomography instrument

      Virtual-OCT: A simulated optical coherence tomography instrument

      We report the virtual instrumentation of both time-domain (TD) and spectral-domain (SD) optical coherence tomography (OCT) systems. With a virtual partial coherence source from either a simulated or measured spectrum, the OCT signals of both A-scan and B-scan were demonstrated. The spectrometric detector's pixel number, dynamic range, noise, as well as spectral resolution can be simulated in the virtual spectral domain (SD-OCT). The virtual-OCT system provides an environment for parameter evaluation and algorithm optimization for experimental OCT instrumentation, and promotes the understanding of OCT imaging and signal post-processing processes.

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    8. Segmentation And Correlation Of Optical Coherence Tomography And X-RAY Images For Breast Cancer Diagnostics.

      Segmentation And Correlation Of Optical Coherence Tomography And X-RAY Images For Breast Cancer Diagnostics.

      Pre-operative X-ray mammography and intraoperative X-ray specimen radiography are routinely used to identify breast cancer pathology. Recent advances in optical coherence tomography (OCT) have enabled its use for the intraoperative assessment of surgical margins during breast cancer surgery. While each modality offers distinct contrast of normal and pathological features, there is an essential need to correlate image -based features between the two modalities to take advantage of the diagnostic capabilities of each technique. We compare OCT to X-ray images of resected human breast tissue and correlate different tissue features between modalities for future use in real-time intraoperative OCT imaging . X-ray ...

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    9. Optical Coherence Tomography of the Living Human Kidney

      Optical Coherence Tomography of the Living Human Kidney

      Acute tubular necrosis (ATN) induced by ischemia is the most common insult to donor kidneys destined for transplantation. ATN results from swelling and subsequent damage to cells lining the kidney tubules. In this study, we demonstrate the capability of optical coherence tomography (OCT) to image the renal microstructures of living human donor kidneys and potentially provide a measure to determine the extent of ATN. We also found that Doppler-based OCT (i.e., DOCT) reveals renal blood flow dynamics that is another major factor which could relate to post-transplant renal function. All OCT/DOCT observations were performed in a noninvasive, sterile ...

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    10. Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin (World Scientific)

      Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin (World Scientific)

      A major challenge for translating cell-based therapies is understanding the dynamics of cells and cell populations in complex in vivo environments. Intravital microscopy has shown great promise for directly visualizing cell behavior in vivo. However, current methods are limited to relatively short imaging times (hours), by ways to track cell and cell population dynamics over extended time-lapse periods (days to weeks to months), and by relatively few imaging contrast mechanisms that persist over extended investigations. We present technology to visualize and quantify complex, multifaceted dynamic changes in natural deformable skin over long time periods using novel multimodal imaging and a ...

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    1-10 of 10
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