1. Articles from TCTMD

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    1. Fewer Women Than Men Get Intracoronary Imaging in PCI, but Why?

      Fewer Women Than Men Get Intracoronary Imaging in PCI, but Why?

      Women undergoing PCI in England and Wales are less likely to receive intracoronary imaging than their male counterparts, data from the British Cardiovascular Intervention Society (BCIS) registry show. The situation grew worse, not better, over a 14-year period. Importantly, female patients may be paying a penalty, too, in terms of survival and major adverse outcomes, Muhammad Rashid, MBBS (Keele University, Stoke-on-Trent, England), and colleagues point out in a new paper, which was published online earlier this week in JACC: Cardiovascular Interventions . Rashid told TCTMD that their study comes on the heels of others showing women have worse outcomes when they ...

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    2. Dragonfly OpStar OCT Catheter Recalled for Loose Marker Band

      Dragonfly OpStar OCT Catheter Recalled for Loose Marker Band

      Abbott has recalled its Dragonfly OpStar imaging catheter, used for imaging the coronary arteries with optical coherence tomography, due to the possibility that the marker band farthest from the tip of the catheter could become loose and harm the patient, the US Food and Drug Administration announced Thursday . The recall has been deemed Class I, the most serious type. The issue has been associated with five incidents and one injury, but no deaths. In two cases, the loose band separated completely from the catheter while it was in use. If that happens and the band remains behind in the patient ...

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      Mentions: Abbott FDA
    3. DOCTORS: Optical Coherence Tomography Improves Stent Placement

      DOCTORS: Optical Coherence Tomography Improves Stent Placement

      The addition of optimal coherence tomography (OCT) to standard fluoroscopy can influence physician decision-making and quantitatively improves post-PCI fractional flow reserve (FFR) in patients with non-ST-elevation acute coronary syndromes, results from the DOCTORS trial show. The study, said lead author Nicolas Meneveau, MD, PhD (University Hospital Jean Minjoz, Besançon, France), is the first randomized controlled trial to support a role for OCT in this setting, although hard clinical endpoint studies are warranted. “We need additional data,” he acknowledged in a morning press conference. “We need additional studies with clinical endpoints before considering incorporating OCT as the standard to use ...

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    4. ILUMIEN II Raises Questions as to What OCT Offers Over IVUS

      ILUMIEN II Raises Questions as to What OCT Offers Over IVUS

      Optical coherence tomography (OCT) and intravascular ultrasound (IVUS) guidance each result in comparable levels of stent expansion, according to post-hoc analysis of 2 prospective studies dubbed ILUMIEN II. On IVUS, “the strongest predictor of early stent thrombosis and restenosis is the absolute degree of stent expansion,” Gregg W. Stone, MD, of Columbia University Medical Center (New York, NY), and colleagues write in their paper published in the November 2015 issue of JACC: Cardiovascular Interventions. Lloyd W. Klein, MD, of Rush Medical College (Chicago, IL), while crediting the researchers for “trying to find a way in which OCT could have an ...

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    5. Positive Signs for OCT Guidance in PCI

      Positive Signs for OCT Guidance in PCI

      No fewer than 3 Hot Line presentations on May 20, 2015, at EuroPCR addressed the question of how well optical coherence tomography (OCT) might inform PCI. One focused on how operators might use the imaging technology to guide decision making, while the others compared OCT with IVUS. Presenting data from the observational ILUMIEN I trial, William Wijns, MD, PhD, of Cardiovascular Center Aalst (Aalst, Belgium), said the study was designed to “capture physician behavior.” ILUMIEN I enrolled 418 subjects indicated for PCI in de novo coronary arteries at 40 centers in the United States, Europe, Japan, Hong Kong, Australia, and ...

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      Mentions: Abbott
    6. Early Healing Profile Established for BioFreedom

      Early Healing Profile Established for BioFreedom

      Paris, France, The first study to demonstrate rapid early healing for BioFreedom™, a novel polymer and carrier-free drug-coated stent (DCS), was presented at EuroPCR 2015 by Professor Stephen Lee, Division of Cardiology, Queen Mary Hospital, University of Hong Kong. Results in the first twelve months demonstrate rapid strut coverage, suggesting an early healing profile for patients using BioFreedom. Lee’s Optical Coherence Tomography (OCT) analysis demonstrated that 86% of struts were covered at one month, and 97% at five months. The BioFreedom stent also showed effective neointimal suppression at nine months and favourable clinical outcomes at twelve months. The EGO ...

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    7. OCT Appears to Help Identify ACS Patients Who Can Forgo Stenting

      OCT Appears to Help Identify ACS Patients Who Can Forgo Stenting

      Optical coherence tomography (OCT) facilitates a staged approach to managing patients with acute coronary syndromes (ACS) and a large thrombus burden. Delayed high-resolution imaging after initial angiography and thrombectomy is linked to reduced thrombus, enabling about 40% of patients to avoid stenting, asserts a prospective pilot study published online July 19, 2014, ahead of print in EuroIntervention .

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    8. OCT Imaging Shows Artery Damage Caused by Transradial Intervention

      OCT Imaging Shows Artery Damage Caused by Transradial Intervention
      Transradial access, widely used outside the United States as an alternative to femoral access for coronary intervention, causes acute injuries and chronic intimal thickening that render the radial artery unusable as a conduit for coronary artery bypass grafting. The findings were published online April 22, 2010, ahead of print in the European Heart Journal. Researchers led by Taishi Yonetsu, MD, of Tsuchiura Kyodo Hospital (Tsuchiura, Japan), used optical coherence tomography (OCT) to examine 73 radial arteries in 69 patients who received transradial coronary intervention at their institution from March 2009 to September 2009. In addition to their main analysis, the ...
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    9. Incomplete Apposition Implicated in Stent Thrombosis

      Another idea would be for clinicians to use OCT to evaluate patients who need to stop taking clopidogrel. “If there is no malapposition, if all struts are covered, then you really don’t need dual antiplatelet therapy,” she said “But if someone had to go for surgery and he’s 1 year out and he’s got a lot of uncovered struts, I would say to the surgeon, ‘You’ve got to keep him on Plavix, I’m sorry. Otherwise he’s going to die. You’re going to create late stent thrombosis.’”
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    10. At 3 Years, SES Maintain Lead Over BMS for Stemi

      The superior clinical benefit of sirolimus-eluting stents (SES) over bare-metal stents (BMS) observed in ST-segment elevation myocardial infarction (STEMI) patients 1 year after treatment is sustained out to 3 years, according to a paper in the February 23, 2010, issue of the Journal of the American College of Cardiology. Of note, the cumulative incidence of death and recurrent MI was equivalent in the SES and BMS groups after clopidogrel withdrawal. Three-year findings from the SESAMI (Sirolimus-Eluting Stent Versus Bare-Metal Stent in Acute Myocardial Infarction) trial were previously presented September 22, 2009, as an oral abstract at the annual Transcatheter Cardiovascular ...
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      Mentions: Cordis
    11. Prior Aspirin Therapy Associated with Less Thrombus in Stemi Patients

      Prior Aspirin Therapy Associated with Less Thrombus in Stemi Patients
      A small study linking previous aspirin therapy with lower thrombus burden in patients undergoing primary percutaneous coronary intervention (PCI) shows the potential mechanism by which the antiplatelet drug may prevent or lessen the damage of an ST-segment elevation myocardial infarction (STEMI), according to findings published online January 25, 2010, ahead of print in the American Journal of Cardiology. Researchers led by Giampaolo Niccoli, MD, PhD, of Catholic University of the Sacred Heart (Rome, Italy), looked at the relationship between previous aspirin therapy and angiographic thrombus grade in 91 consecutive patients at their institution undergoing primary PCI for a first STEMI ...
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    1-11 of 11
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