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    1. Conference Report: Eighth Annual AACR International Conference on Frontiers in Cancer Prevention Research

      Conference Report: Eighth Annual AACR International Conference on Frontiers in Cancer Prevention Research
      The Eighth Annual Frontiers in Cancer Prevention Research meeting was held in Houston, Texas, in November 2009. This report highlights significant presentations that advance the fields of chemoprevention, clinical trial recruitment and retention, cancer screening including optical imaging, energy balance, and nutritional epidemiology, and health communications and decision making. In findings from the randomized Reduction by Dutasteride of Prostate Cancer Events trial, dutasteride reduced the risk of biopsy-detectable prostate cancer in high-risk men by 23% compared with placebo. Important clues about the dosing and window of susceptibility for supplementation with choline, vitamin D, and folate were revealed from epigenetic research ...
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    2. Optical coherence tomography imaging of preneoplastic lung lesion

      Although autofluorescence bronchoscopy improves the detection rate of high grade dysplasia and carcinoma in-situ compares to white-light examination, the natural history of preneoplastic bronchial lesions is still poorly understood because the biopsy procedure for histological confirmation can mechanically remove these small lesions. The lack of accurate information regarding the spontaneous progression and regression rates of preneoplastic lesions make if difficult to assess the effect of chemoprevention agents. It is therefore important to develop non-biopsy methods that can characterize preneoplastic lesions in the bronchial epithelium. Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extra-cellular structures ...

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