The Effect of Radiologically Isolated Syndrome on Retinal and Choroidal Hemodynamics - An Optical Coherence Tomography Angiography Study

Purpose: To evaluate vessel density of retinal plexuses and optic nerve head (ONH) and flow of choriocapillaris to detect possible subclinical retinal microvascular changes associated with the radiologically isolated syndrome (RIS). Materials and Methods: We analyzed 26 eyes of 26 participants diagnosed with RIS and 39 age and sex-matched healthy controls in this prospective, cross-sectional study. The superficial (SCP) and deep capillary plexus (DCP), foveal avascular zone (FAZ) parameters, the flow area of choriocapillaris were evaluated using optical coherence tomography angiography (OCTA). Results: Vessel density (VD) of the parafovea (p = 0.045) and parafoveal subregions (p = 0.049 for superior ...