1. Articles from UroToday

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    1. Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Introduction and Objectives: Optical Coherence Tomography (OCT) has potential to provide real-time information on UUT-UC grade and stage. In this study we compare a) biopsy and b) OCT with gold standard histopathology of the resected specimen (HRS) for grading and staging of low- and high-grade UUT-UC. Methods: 16 patients with UUT-UC underwent diagnostic URS, including OCT and biopsy of places with visible tumour. The 2.7 Fr OCT probe was delivered through the ureteroscopes work channel. Subsequently biopsy was performed. At a later stage, patients underwent nephroureterectomy. For staging by OCT, in-house developed protocols were used and visible lesions were ...

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    2. Full field optical coherence tomography (FFOCT) of prostate biopsies: A step towards pre-histological diagnosis?

      Full field optical coherence tomography (FFOCT) of prostate biopsies: A step towards pre-histological diagnosis?

      Full-field optical coherence tomography (FFOCT) may be a potential additional tool in the strategy of prostate cancer detection. If the technique can be performed safely during transrectal ultrasound (TRUS) biopsy, and without adding significant time to the procedure, the information provided by FFOCT imaging during biopsy would increase the performance level of cancer detection. FFOCT imaging would allow immediate additional sampling in an area suspicious of cancer involvement, thus optimizing its characterization. In cases where there’s an absence of suspicious FFOCT image results in other areas, sampling could be limited to one core, thus decreasing the total number of ...

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    3. Exclusive report from the International Society for the Study of Bladder Pain Syndrome (ESSIC) 8th Annual Meeting

      Exclusive report from the International Society for the Study of Bladder Pain Syndrome (ESSIC) 8th Annual Meeting
      Dr. Zaitcev from Moscow discussed a new tool that may help to identify the bladder lesions of BPS. He used optical coherence tomography in 21 women with Hunner’s lesions who underwent bladder distention under anesthesia. Optical coherence tomography is a novel method that can be used to construct cross-sectional images of tissue microstructure with high spatial resolution. It measures optical scattering of light by comparing the backscattered or back reflected light signal to a controlled reference signal. The principle is similar to B-mode ultrasound, except light is the medium rather than sound. In all cases, optical coherence tomograpy allowed ...
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