Yu Chen

1. Mentioned In 17 Articles

2. Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT)

   Explore Article IEEE Xplore (Aug 9 2010) Oncology

   Multimodal imaging represents one of the current trends in the development of biophotonics imaging technologies. This paper briefly reviews current multimodal biophotonics imaging platforms in macroscopic, microscopic, and mesoscopic (or millimeter) scales. We also present a combined optical coherence tomography and line-scan fluorescence laminar optical tomography system for co-registered structural and molecular imaging with millimeter-scale imaging depth. Experimental results using a capillary phantom filled with the fluorescence dye Cy5.5 and ... (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Johns Hopkins University   Yu Chen

3. Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT) for Depth-Resolved Subsurface Cancer Imaging

   Explore Article opticsinfobase.org (Apr 11 2010) Oncology

   We developed a combined optical coherence tomography (OCT) and fluorescence laminar optical tomography (FLOT) system for co-registered depth-resolved structural and molecular imaging. Experimental results using a mouse model with human breast cancer xenograft are presented. (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Johns Hopkins University   Yu Chen

4. Optical Coherence Tomography of Human Kidney

   Explore Article The Journal of Urology (Mar 18 2010) Urology

   Purpose To determine histopathological status of living human kidneys in real time and a noninvasive fashion would be a significant advancement in renal disease diagnosis. Recently we reported that optical coherence tomography has the requisite high spatial resolution to noninvasively determine histopathological changes in rodent kidneys with μm scale resolution. We established whether optical coherence tomography could 1) effectively penetrate the connective tissue capsule surrounding human kidneys, 2) provide a ... (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Thorlabs   Alex E. Cable

5. Cellular resolution ex vivo imaging of gastrointestinal tissues with optical coherence microscopy

   Explore Article SPIE Digital Library (Mar 2 2010) Microscopy

   Optical coherence microscopy (OCM) combines confocal microscopy and optical coherence tomography (OCT) to improve imaging depth and contrast, enabling cellular imaging in human tissues. We aim to investigate OCM for ex vivo imaging of upper and lower gastrointestinal tract tissues, to establish correlations between OCM imaging and histology, and to provide a baseline for future endoscopic studies. Co-registered OCM and OCT imaging were performed on fresh surgical specimens and endoscopic ... (Read Full Article)
   

   Comment on Article Mentions:   Yu Chen   Aaron D. Aguirre   James G. Fujimoto

6. Investigation of pore structure and cell distribution in EH-PEG hydrogel scaffold using optical coherence tomography and fluorescence microscopy

   Explore Article SPIE Digital Library (Feb 11 2010) Microscopy

   ...Univ. of Maryland, College Park (USA) James Jiang, Hongzhou Ma, and Alex Cable Thorlabs, Inc. (USA) Yu Chen Univ. of Maryland, College Park (USA) Macroporous^ EH-PEG hydrogels fabricated by porogen-leaching ... (Read Full Article)
   

   Comment on Article Mentions:   Thorlabs   Alex E. Cable   Yu Chen

7. Co-registered optical coherence tomography and fluorescence molecular imaging for simultaneous morphological and molecular imaging

   Explore Article Institute of Physics (Dec 10 2009)

   ...Biying Xu^3, Gary Griffiths^3, James Jiang^4, Hongzhou Ma^4, Alex Cable^4, Ronald M Summers^2,5 and Yu Chen^1,6 ^1 Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA ^... (Read Full Article)
   

   Comment on Article Mentions:   Thorlabs   Alex E. Cable   Yu Chen

8. Multi-modality optical tomography for simultaneous morphological and molecular imaging

   Explore Article SPIE Digital Library (Nov 25 2009)

   ...: Xingde Li, Qingming Luo, Vasilis Ntziachristos, Yoshiaki Yasuno ABSTRACT Shuai Yuan, Qian Li, and Yu Chen Univ. of Maryland, College Park (USA) Optical^ coherence tomography (OCT) is an emerging medica... (Read Full Article)
   

   Comment on Article Mentions:   Yu Chen   Qian Li   University of Maryland

9. Automated Quantification of Microstructural Dimensions of the Human Kidney using Optical Coherence Tomography

   Explore Article Optical Coherence Tomography News (Sep 6 2009)

   ... for diagnosis and management of kidney diseases. For more information see recent Article. Courtesy Yu Chen. (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Thorlabs   Yu Chen

10. Automated quantification of microstructural dimensions of the human kidney using optical coherence tomography (OCT)

    Explore Article opticsinfobase.org (Aug 25 2009)

    ...eter M. Andrews, Chao-Wei Chen, Andrew Paek, Renee Naphas, Shuai Yuan, James Jiang, Alex Cable, and Yu Chen Optics Express, Vol. 17, Issue 18, pp. 16000-16016 doi:10.1364/OE.17.016000 » V... (Read Full Article)
    

    Comment on Article Mentions:   Alex E. Cable   Yu Chen   Qian Li

11. Three-dimensional coregistered optical coherence tomography and line-scanning fluorescence laminar optical tomography

    Explore Article opticsinfobase.org (May 18 2009)

    ...-scanning fluorescence laminar optical tomography Shuai Yuan, Qian Li, James Jiang, Alex Cable, and Yu Chen Optics Letters, Vol. 34, Issue 11, pp. 1615-1617 doi:10.1364/OL.34.001615 » V... (Read Full Article)
    

    Comment on Article Mentions:   Alex E. Cable   Yu Chen   Qian Li

12. Combining optical coherence tomography with fluorescence molecular imaging: towards simultaneous morphology and molecular imaging

    Explore Article SPIE Digital Library (Feb 24 2009)

    ...ngzhou Ma and Alex Cable Thorlabs, Inc. (USA) Ronald M. Summers National Institutes of Health (USA) Yu Chen Univ. of Maryland, College Park (USA) Optical^ coherence tomography (OCT) provides high-re... (Read Full Article)
    

    Comment on Article Mentions:   Thorlabs   Alex E. Cable   University of Maryland

13. Combining optical coherence tomography with fluorescence molecular imaging: towards simultaneous morphology and molecular imaging

    Explore Article SPIE Digital Library (Feb 24 2009)

    ...ngzhou Ma and Alex Cable Thorlabs, Inc. (USA) Ronald M. Summers National Institutes of Health (USA) Yu Chen Univ. of Maryland, College Park (USA) Optical^ coherence tomography (OCT) provides high-re... (Read Full Article)
    

    Comment on Article Mentions:   Thorlabs   Alex E. Cable   University of Maryland

14. Optical Coherence Tomography (OCT) Reveals Depth-Resolved Dynamics during Functional Brain Activation

    Explore Article ScienceDirect (Dec 12 2008)

    Optical intrinsic signal imaging (OISI) provides two-dimensional, depth-integrated activation maps of brain activity. Optical coherence tomography (OCT) provides depth-resolved, cross-sectional images of functional brain activation. Co-registered OCT and OISI imaging was performed simultaneously on the rat somatosensory cortex through a thinned skull during forepaw electrical stimulation. Fractional signal change measurements made by OCT revealed a functional signal that correlates well with that of the intrinsic hemodynamic signals and provides depth-resolved, ... (Read Full Article)
    

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Massachusetts General Hospital

15. High-resolution optical coherence tomography imaging of the living kidney

    Explore Article Nature Publishing Group (Feb 29 2008)

    Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can provide non-invasive, cross-sectional, high-resolution images of tissue morphology in situ and in real-time. In the present series of studies, we used a high-speed OCT imaging system equipped with a frequency-swept laser light source (1.3 m wavelength) to study living kidneys in situ. Adult, male Munich–Wistar rats were anesthetized, a laparotomy was performed and the living kidneys were exposed ... (Read Full Article)
    

    Comment on Article Mentions:   Desmond C. Adler   University of Maryland   Massachusetts Institute of Technology

16. Three-dimensional endomicroscopy using optical coherence tomography

    Explore Article Nature Publishing Group (Feb 26 2008) Gastroenterology

    ...plications. Three-dimensional endomicroscopy using optical coherence tomography Desmond C. Adler^1, Yu Chen^1, Robert Huber^1,^2, Joseph Schmitt^3, James Connolly^4 & James G. Fujimoto^1 Abstract Optical co... (Read Full Article)
    

    Comment on Article Mentions:   LightLab Imaging   Massachusetts Institute of Technology   James G. Fujimoto

17. In vivo endomicroscopy using three-dimensional optical coherence tomography and Fourier domain mode locked lasers

    Explore Article SPIE Digital Library (Feb 19 2008) Gastroenterology

    We report an endoscopic optical coherence tomography (OCT) system based on a Fourier Domain Mode Locked (FDML) laser, a novel data acquisition (DAQ) system with optical frequency clocking, and a high-speed spiralscanning fiber probe. The system is capable of acquiring three-dimensional (3D) in vivo ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684708 (2008)] published Tue Feb 19, 2008. (Read Full Article)
    

    Comment on Article Mentions:   Massachusetts Institute of Technology   Robert A. Huber   Yu Chen

18. Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues

    Explore Article opticsinfobase.org (Feb 8 2008) Gastroenterology

    Yu Chen, Aaron D. Aguirre, Pei-Lin Hsiung, Shu-Wei Huang, Hiroshi Mashimo, Joseph M. Schmitt, James G. Fuji... (Read Full Article)
    

    Comment on Article Mentions:   James G. Fujimoto   Joseph M. Schmitt   Pei-Lin Hsiung

1-17 of 17