University of Maryland

1. Mentioned In 23 Articles

2. Angioplasty Video: New Imaging Technique Improves Angioplasty (Video)

   Explore Article Insidermedicine (Aug 11 2010) Cardiology

   From Maryland - Advances in imaging may greatly enhance angioplasty, according to a report published in Review of Scientific Instruments. Researchers added optical coherence tomography to the baloon tipped catheter normally inserted into the arteries to flatten plaque and improve blood flow, thereby making it possible to monitor the inflation of the balloon itself. (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Guy Lamouche   Sebastien Vergnole

3. Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT)

   Explore Article IEEE Xplore (Aug 9 2010) Oncology

   Multimodal imaging represents one of the current trends in the development of biophotonics imaging technologies. This paper briefly reviews current multimodal biophotonics imaging platforms in macroscopic, microscopic, and mesoscopic (or millimeter) scales. We also present a combined optical coherence tomography and line-scan fluorescence laminar optical tomography system for co-registered structural and molecular imaging with millimeter-scale imaging depth. Experimental results using a capillary phantom filled with the fluorescence dye Cy5.5 and ... (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Johns Hopkins University   Yu Chen

4. Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT) for Depth-Resolved Subsurface Cancer Imaging

   Explore Article opticsinfobase.org (Apr 11 2010) Oncology

   We developed a combined optical coherence tomography (OCT) and fluorescence laminar optical tomography (FLOT) system for co-registered depth-resolved structural and molecular imaging. Experimental results using a mouse model with human breast cancer xenograft are presented. (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Johns Hopkins University   Yu Chen

5. Optical Coherence Tomography of Human Kidney

   Explore Article The Journal of Urology (Mar 18 2010) Urology

   ...gy. Correspondence: Fischell Department of Bioengineering, 2330A Jeong H. Kim Engineering Building, University of Maryland, College Park, Maryland 20742 (telephone: 301-405-3439; FAX: 301-405-9953 (Read Full Article)
   

   Comment on Article Mentions:   University of Maryland   Thorlabs   Alex E. Cable

6. Investigation of pore structure and cell distribution in EH-PEG hydrogel scaffold using optical coherence tomography and fluorescence microscopy

   Explore Article SPIE Digital Library (Feb 11 2010) Microscopy

   Macroporous EH-PEG hydrogels fabricated by porogen-leaching method are characterized by optical coherence tomography (OCT). High-resolution OCT visualizes the microstructures of the engineered tissue scaffolds in threedimensions. It also enables subsequent image processing to investigate several key morphological design parameters for macroporous scaffolds. Image processing algorithms are then presented to automatically quantify the pore size, porosity, and pore interconnectivity. The results indicated that those parameters highly depend on the porogen size. ... (Read Full Article)
   

   Comment on Article Mentions:   Thorlabs   Alex E. Cable   Yu Chen

7. Co-registered optical coherence tomography and fluorescence molecular imaging for simultaneous morphological and molecular imaging

   Explore Article Institute of Physics (Dec 10 2009)

   ... Ma^4, Alex Cable^4, Ronald M Summers^2,5 and Yu Chen^1,6 ^1 Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA ^2 Imaging Biomarkers and Computer-aided Diagnosis Laboratory, Departm... (Read Full Article)
   

   Comment on Article Mentions:   Thorlabs   Alex E. Cable   Yu Chen

8. Multi-modality optical tomography for simultaneous morphological and molecular imaging

   Explore Article SPIE Digital Library (Nov 25 2009)

   Optical coherence tomography (OCT) is an emerging medical imaging technology that can generate high resolution cross-sectional imaging (1-2 mm in depth) of tissue microstructure in situ and in real time. Fluorescence imaging provides tissue biochemical, metabolism, and molecular information by measuring fluorescence intensity or spectroscopy of either intrinsic fluorophores or exogenous contrast agents. The combination of these two modalities provides complementary morphological, functional and molecular information to comprehensively assess tissue ... (Read Full Article)
   

   Comment on Article Mentions:   Yu Chen   Qian Li   University of Maryland

9. Developmental Aspects of the Upper Airway

   Explore Article pats.atsjournals.org (Sep 10 2009) Otolaryngology , Pulmonology

   The upper airway serves three important functions: respiration, swallowing, and speech. During development it undergoes significant structural and functional changes that affect its size, shape, and mechanical properties. Abnormalities of the upper airway require prompt attention, because these often alter ventilatory patterns and gas exchange, particularly during sleep when upper airway motor tone and ventilatory drive are diminished. Recognizing the relationship of early life events to lung health and disease, ... (Read Full Article)
   

   Comment on Article Mentions:   University of Wisconsin   University of Maryland   Johns Hopkins University

10. Automated Quantification of Microstructural Dimensions of the Human Kidney using Optical Coherence Tomography

    Explore Article Optical Coherence Tomography News (Sep 6 2009)

    ...ally-resolved information for clinical applications. Recenty Qian Li and other researchers from the University of Maryland, Georgetown University, and Thorlabs demonstrated development of an automatic algorithm to quantify... (Read Full Article)
    

    Comment on Article Mentions:   University of Maryland   Thorlabs   Yu Chen

11. Automated quantification of microstructural dimensions of the human kidney using optical coherence tomography (OCT)

    Explore Article opticsinfobase.org (Aug 25 2009)

    Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can non-invasively provide cross-sectional, highresolution images of tissue morphology in situ and in real-time. We previously demonstrated that OCT is capable of visualizing characteristic kidney anatomic structures, including blood vessels, uriniferous tubules,glomeruli, and renal capsules on a Munich–Wistar rat model. Because the viability of a donor kidney is closely correlated with its tubular morphology, and a large amount of ... (Read Full Article)
    

    Comment on Article Mentions:   Alex E. Cable   Yu Chen   Qian Li

12. Three-dimensional coregistered optical coherence tomography and line-scanning fluorescence laminar optical tomography

    Explore Article opticsinfobase.org (May 18 2009)

    We present a combined optical coherence tomography (OCT) and line-scanning fluorescence laminar optical tomography (FLOT) system. This hybrid system enables coregistered structural and molecular imaging in 3D with 10–100 um resolution and millimeter-scale imaging depth. Experimental results on a capillary phantom with fluorescence dye Cy5.5 using an OCT/FLOT imaging system have been demonstrated. (Read Full Article)
    

    Comment on Article Mentions:   Alex E. Cable   Yu Chen   Qian Li

13. Respiratory gating of anatomical optical coherence tomography images of the human airway

    Explore Article opticsinfobase.org (Apr 6 2009) Pulmonology

    Anatomical optical coherence tomography (aOCT) is a longrange endoscopic imaging modality capable of quantifying size and shape of the human airway. A challenge to its in vivo application is motion artifact due to respiratory-related movement of the airway walls. This paper represents the first demonstration of respiratory gating of aOCT airway data, and introduces a novel error measure to guide appropriate parameter selection. Results indicate that at least four gates ... (Read Full Article)
    

    Comment on Article Mentions:   David R. Hillman   University of Maryland   Julian J. Armstrong

14. Intraoperative detection of intimal lipid in the radial artery predicts degree of postoperative spasm

    Explore Article atherosclerosis-journal.com (Mar 5 2009) Cardiology

    Background: The radial artery's (RA) tendency to spasm when used as a bypass graft may relate to features of the RA itself. We imaged RA conduits before and after CABG in order to characterize intimal abnormalities that might relate to the risk of spasm.Methods: RA conduits from thirty-two CABG patients were imaged intraoperatively using catheter-based optical coherence tomography (OCT) and again on day 5 using 64-channel MDCT angiography. The change ... (Read Full Article)
    

    Comment on Article Mentions:   University of Maryland   LightLab Imaging   Boston University

15. Combining optical coherence tomography with fluorescence molecular imaging: towards simultaneous morphology and molecular imaging

    Explore Article SPIE Digital Library (Feb 24 2009)

    Optical coherence tomography (OCT) provides high-resolution, cross-sectional imaging of tissue microstructure in situ and in real-time, while fluorescence molecular imaging (FMI) enables the visualization of basic molecular processes. There are great interests in combining these two modalities so that the tissue's structural and molecular information can be obtained simultaneously. This could greatly benefit biomedical applications such as detecting early diseases and monitoring therapeutic interventions. In this research, a new optical ... (Read Full Article)
    

    Comment on Article Mentions:   Thorlabs   Alex E. Cable   University of Maryland

16. Optical Coherence Tomography (OCT) Reveals Depth-Resolved Dynamics during Functional Brain Activation

    Explore Article ScienceDirect (Dec 12 2008)

    Optical intrinsic signal imaging (OISI) provides two-dimensional, depth-integrated activation maps of brain activity. Optical coherence tomography (OCT) provides depth-resolved, cross-sectional images of functional brain activation. Co-registered OCT and OISI imaging was performed simultaneously on the rat somatosensory cortex through a thinned skull during forepaw electrical stimulation. Fractional signal change measurements made by OCT revealed a functional signal that correlates well with that of the intrinsic hemodynamic signals and provides depth-resolved, ... (Read Full Article)
    

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Massachusetts General Hospital

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