About University of Houston
University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers. Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).
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Differential permeability rate and percent clearing of glucose in different regions in rabbit sclera
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Assessing molecular diffusion in tissues using optical coherence tomography
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Imaging of cardiovascular dynamics in early mouse embryos with swept source optical coherence tomography
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Mentioned In 47 Articles
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Postdoctoral Position in The Biomedical Optics Laboratory at the University of Houston
Explore Article Optical Coherence Tomography News (Aug 29 2010)
...dical Optics Laboratory (http://www.egr.uh.edu/bol/) in Department of Biomedical Engineering at the University of Houston, TX invites applications for a postdoctoral scholar position in the area of optical coherence tomog... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston
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Depth-resolved imaging and detection of micro-retroreflectors within biological tissue using Optical Coherence Tomography
Explore Article opticsinfobase.org (Aug 2 2010)
A new approach to in vivo biosensor design is introduced, based on the use of an implantable micron-sized retroreflector-based platform and non-invasive imaging of its surface reflectivity by Optical Coherence Tomography (OCT). The possibility of using OCT for the depth-resolved imaging and detection of micro-retroreflectors in highly turbid media, including tissue, is demonstrated. The maximum imaging depth for the detection of the micro-retroreflector-based platform within the surrounding media was found ... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston Saratov State University
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Comparison of Optical Coherence Tomography and Scanning Laser Polarimetry Measurements in Patients with Multiple Sclerosis
Explore Article LWW Online (May 21 2010)
Purpose. To compare optical coherence tomography (OCT) and scanning laser polarimetry (GDx) measurements of the retinal nerve fiber layer (RNFL) in multiple sclerosis (MS) patients with and without optic neuritis (ON). Methods. OCT and GDx were performed on 68 MS patients. Qualifying eyes were divided into two groups: 51 eyes with an ON history >=6 months before (ON eyes) and 65 eyes with no history of ON (non-ON eyes). Several ... (Read Full Article)
Comment on Article Mentions: University of Houston Han Cheng
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The Embryonic Heart: Imaging Life as it Happens - University of Houston Professor Captures Video of Heart Before it Begins to Beat (Video Snippet)
Explore Article Optical Coherence Tomography News (Apr 2 2010)
... it happens by capturing video of the embryonic heart before it begins beating. A professor at the University of Houston, in collaboration with scientists at Baylor College of Medicine, is doing just that. Kiri...
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Comment on Article Mentions: Kirill V. Larin Baylor College of Medicine University of Houston
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Comparison of multifocal visual evoked potential, standard automated perimetry and optical coherence tomography in assessing visual pathway in multiple sclerosis patients
Explore Article Multiple Sclerosis (Mar 7 2010)
...eural degeneration (reduced amplitude), revealed more abnormality than HVF or OCT in MS patients. 1 University of Houston, College of Optometry, Houston, Texas, USA 2 Section of Ophthalmology, Department of Head and Neck ... (Read Full Article)
Comment on Article Mentions: University of Houston Han Cheng
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Imaging of mouse embryonic eye development using optical coherence tomography
Explore Article SPIE Digital Library (Mar 2 2010)
Congenital abnormalities are often caused by genetic disorders which alter the normal development of the eye. Embryonic eye imaging in mouse model is important for understanding of normal and abnormal eye development and can contribute to prevention and treatment of eye defects in humans. In this study, we used Swept Source Optical Coherence Tomography (SS-OCT) to image eye structure in mouse embryos at 12.5 to 17.5 days post coitus (dpc). ...
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Comment on Article Mentions: Kirill V. Larin Baylor College of Medicine University of Houston
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Measurement of vibrations induced on the surface of crystalline eye lens using PhS-SDOCT
Explore Article SPIE Digital Library (Mar 2 2010)
Experimental assessment of stiffness of crystalline lens of the eye can help in understanding several ocular diseases. Studies have shown that stiffness of the eye lens increases with age that might contribute to loss of accommodation. The stiffness of the lens could be assessed by measuring mechanically induced surface waves propagating on its surface. Here we present preliminary results on phase sensitive spectral domain optical coherence tomography (PhS-SDOCT) measurements of ...
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Comment on Article Mentions: Kirill V. Larin Stepan A. Baranov University of Houston
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Quantification of microbubbles in blood with phase-sensitive SSOCT
Explore Article SPIE Digital Library (Feb 23 2010)
We have developed a phase stabilized swept source optical coherence tomography (PhS-SSOCT), that shows an axial resolution of 10 µm, phase sensitivity of 0.04 radians, imaging depth of up to 6 mm in air and a scanning speed of 20 kHz for a single A-line. In this paper, the PhS-SSOCT is applied to quantify gas microbubbles in blood in vitro. The results indicate that the system is able to detect ...
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Comment on Article Mentions: Kirill V. Larin University of Houston
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Multiple-cardiac-cycle noise reduction in dynamic optical coherence tomography of the embryonic heart and vasculature
Explore Article opticsinfobase.org (Nov 20 2009)
Recent progress in optical coherence tomography (OCT) allows imaging dynamic structures and fluid flow within scattering tissue, such as the beating heart and blood flow in mouse embryos. Accurate representation and analysis of these dynamic behaviors require reducing the noise of the acquired data. Although noise can be reduced by averaging multiple neighboring pixels in space or time, such operations reduce the effective spatial or temporal resolution that can be ...
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Comment on Article Mentions: Kirill V. Larin Baylor College of Medicine University of Houston
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Bio-optics: Everywhere at once
Explore Article BioOptics World (Nov 10 2009)
...e OSA’s Frontiers in Optics (FiO; October 11–15, San Jose, CA) was that done by Kirill Larin of the University of Houston (TX) involving live imaging of cardio dynamics–and measurement of blood flow from individual cells–... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin Sensors Unlimited National Institutes of Health
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Monitoring of Molecular Permeability in Tissues Using Optical Coherence Tomography
Explore Article Optical Coherence Tomography News (Oct 25 2009)
Feature Of The Week 10/25/09: Researchers at the Biomedical Optics Laboratory at the University of Houston led by Dr. Kirill Larin, and the Research Educational Institute of Optics and Biophotonics at Sarat...
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Comment on Article Mentions: Kirill V. Larin Mohamad G. Ghosn Saratov State University
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A 3D Video of the Embryonic Heartbeat
Explore Article Technology Review (Oct 22 2009)
... of providing insights into how these developmental problems might be prevented, researchers at the University of Houston have developed an imaging system they're using to take 3D video of the mammalian heart as it forms.... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston
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Monitoring of glucose permeability in monkey skin in vivo using Optical Coherence Tomography
Explore Article www3.interscience.wiley.com (Oct 12 2009)
Topical trans-dermal delivery of drugs has proven to be a promising route for treatment of many dermatological diseases. The aim of this study is to monitor and quantify the permeability rate of glucose solutions in rhesus monkey skin noninvasively in vivo as a primate model for drug diffusion. A time-domain Optical Coherence Tomography (OCT) system was used to image the diffusion of glucose in the skin of anesthetized monkeys for ... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston Saratov State University
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Live imaging of rat embryos with Doppler swept-source optical coherence tomography
Explore Article Scitation (Oct 1 2009)
The rat has long been considered an excellent system to study mammalian embryonic cardiovascular physiology, but has lacked the extensive genetic tools available in the mouse to be able to create single gene mutations. However, the recent establishment of rat embryonic stem cell lines facilitates the generation of new models in the rat embryo to link changes in physiology with altered gene function to define the underlying mechanisms behind congenital ... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston
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Bio-optics breakthroughs: Highlights of medical and bioscience research at Frontiers in Optics 2009
Explore Article EurekAlert! (Sep 29 2009)
...s a long history of understanding cardiovascular development and diseases, says Kirill Larin of the University of Houston, very little is known about the dynamics of the normal and abnormal embryonic heart. Half a century...
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Comment on Article Mentions: Kirill V. Larin Baylor College of Medicine University of Houston


Recent Comments
Eric Swanson » Jim Fujimoto video: Biophotonics and optical coherence tomography
Great video Jim!
dariemihaela » Gary S. Mintz
Dear Prof. Dr. Gary S. Mintz, You are an extraordinary expert in imaging, an intelligence ...
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