Stephen A. Boppart

About Stephen A. Boppart

Stephen A. Boppart is a professor in the Biophotonics Imaging Laboratory at the University of Illinois Urbana Champaign.  Dr. Boppart received his Ph.D. from the Massachusetts Institute of Technology in 1998, followed by a M.D. from Harvard Medical School in 2000. Currently Prof. Boppart is a full-time faculty member in the Beckman Institute Nanoelectronics and Biophotonics Group as well as an associate professor in the UIUC Department of Electrical and Computer Engineering and the Bioengineering Department. In January 2007, he was named the Founding Director of the Mills Breast Cancer Institute at Carle Foundation Hospital. Dr. Boppart is also a Clinical Research Physician in the UI College of Medicine-Urbana. His fields of professional interest include optical imaging (specifically in Optical Coherence Tomography) and biophotonics in medicine and biology.

Quotes

1. “ What is novel about this whole approach and this work is that we’re using external magnetic forces to move nanoparticles within tissue, to modulate them...Most other particles will localize somewhere and typically sit there. They may provide a signal change, but they don’t physically move. No other particle is dynamic like this, which is a unique way to generate contrast. ”

   In New Imaging Method uses Magnetic Nanoparticles that Move

2. “ So now we have a platform where we can target these to a tumor, find them with contrast, measure the mechanical properties, and treat it right there. ”

   In New Imaging Method uses Magnetic Nanoparticles that Move

3. “ And this is found a day later after the surgery has ended....It means that the patient has to come back for another procedure, with all the risks and costs associated with that, and all the anxiety. Another downside for the patient is if there are any tumor cells left behind. These patients are likely to relapse, as there is a fairly high local recurrence rate of tumors that grow back in that area. ”

   In Optics may speed breast cancer diagnosis

4. “ Intraoperative OCT has the potential to provide diagnostically useful information about margin status in real time, at the point of care, rather than relying on postoperative histopathology. ”

   In Optical Coherence Tomography Identifies Surgical Margins for Breast Cancer Intraoperatively

5. “ The imaging depth was equivalent to the tissue depth that pathologists typically examine postoperatively to determine if the margin is negative, close or positive...Image features could also be used to identify structures such as surface blood or cauterised tissue and distinguish these image artifacts from normal and tumour tissue ”

   In Optical Coherence Tomography Identifies Surgical Margins for Breast Cancer Intraoperatively

1. Mentioned In 69 Articles

2. Magnetomotive optical coherence tomography

   Explore Article uspto.gov (Jul 6 2010) Patents

   A spectral-domain magnetomotive optical coherence tomography apparatus, includes (a) a spectral-domain optical coherence tomography device, and (b) a magnet. The magnet is coupled with the optical coherence tomography device so that changes in the magnetic field are coordinated with collection of data by the optical coherence tomography device. This device may be used to examine a sample by spectral-domain magnetomotive optical coherence tomography, which includes examining the sample with a ... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Vasilica Crecea

3. Dynamic spectral-domain optical coherence elastography for tissue characterization

   Explore Article opticsinfobase.org (Jun 16 2010)

   ...ical coherence elastography for tissue characterization Xing Liang, Steven G. Adie, Renu John, and Stephen A. Boppart Optics Express, Vol. 18, Issue 13, pp. 14183-14190 (2010) doi:10.1364/OE.18.014183 » V... (Read Full Article)
   

   Comment on Article Mentions:   Xing Liang   Steven G. Adie   Stephen A. Boppart

4. Interferometric Synthetic Aperture Microscopy: Microscopic Laser Radar

   Explore Article eweb.osa.org (Jun 4 2010)

   Combining optical coherence tomography instrumentation and the principles of synthetic aperture radar, researchers have developed a new method for reconstructing 3-D optical images—even in regions that are out of focus in the raw data. Doctors may soon be able to use this approach as a noninvasive diagnostic tool in clinical settings. Microscopic 3-D optical imaging provides guidance to tomorrow’s doctors during surgical interventions. In many clinical scenarios, doctors require high-resolution ... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Tyler S. Ralston

5. Simple Equations Power Scott Carney's Research

   Explore Article beckman.illinois.edu (Jun 2 2010)

   ...ey is taking advantage of the power of Maxwell’s equations as he works with Beckman colleagues like Stephen Boppart and Rohit Bhargava from the Bioimaging Science and Technology group to advance imaging modalities s......hematics around it, and make new predictions about the way the world works.” One collaboration with Boppart used Carney’s computational approach to take blurry optical microscopy images and turn them into sh... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   P. Scott Carney

6. New Imaging Method uses Magnetic Nanoparticles that Move

   Explore Article beckman.illinois.edu (May 28 2010)

   ... of the National Academy of Sciences April 19. Corresponding author is Beckman Institute researcher Stephen Boppart, M.D., Ph.D. “What is novel about this whole approach and this work is that we’re using external ma......s that we’re using external magnetic forces to move nanoparticles within tissue, to modulate them,” Boppart said. “Most other particles will localize somewhere and typically sit there. They may provide a sig... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

7. Contrast enhanced spectroscopic optical coherence tomography

   Explore Article uspto.gov (May 25 2010) Patents

   ... nanoparticles, such as those described in copending U.S. patent application Ser. No. 10/753,972 to Boppart et al., filed Jan. 8, 2004, and published as US 2005/0171433 A1. Plasmon-resonant nanoparticles inc... (Read Full Article)
   

   Comment on Article Mentions:   Basler   Stephen A. Boppart   University of Illinois at Urbana-Champaign

8. Cross-validation of interferometric synthetic aperture microscopy and optical coherence tomography

   Explore Article opticsinfobase.org (May 10 2010) Microscopy

   ...ture microscopy and optical coherence tomography Tyler S. Ralston, Steven G. Adie, Daniel L. Marks, Stephen A. Boppart, and P. Scott Carney Optics Letters, Vol. 35, Issue 10, pp. 1683-1685 (2010) » View Full Text: Acro... (Read Full Article)
   

   Comment on Article Mentions:   Steven G. Adie   Tyler S. Ralston   Daniel L. Marks

9. Sonification of optical coherence tomography data and images

   Explore Article opticsinfobase.org (Apr 27 2010) Ophthalmology

   ...ation of optical coherence tomography data and images Adeel Ahmad, Steven G. Adie, Morgan Wang, and Stephen A. Boppart Optics Express, Vol. 18, Issue 10, pp. 9935-9945 (2010) * OCIS Codes: * (100.2960) Image processing... (Read Full Article)
   

   Comment on Article Mentions:   Steven G. Adie   Stephen A. Boppart   University of Illinois at Urbana-Champaign

10. In vivo magnetomotive optical molecular imaging using targeted magnetic nanoprobes

    Explore Article pnas.org (Apr 22 2010)

    ...my L. Oldenburg^a, 6. Marina Marjanovic^a, 7. Justin P. Haldar^a, 8. Bradley P. Sutton^a,^b, and 9. Stephen A. Boppart^a,^b,^c,^1 1. ^aBeckman Institute for Advanced Science and Technology, 2. ^bDepartment of Bioengine... (Read Full Article)
    

    Comment on Article Mentions:   University of Illinois at Urbana-Champaign   Steven G. Adie   Amy L. Oldenburg

11. Optical Coherence Tomography: The Intraoperative Assessment of Lymph Nodes in Breast Cancer

    Explore Article IEEE Xplore (Mar 29 2010) Oncology

    During breast-conserving surgeries, axillary lymph nodes draining from the primary tumor site are removed for disease staging. Although a high number of lymph nodes are often resected during sentinel and lymph-node dissections, only a relatively small percentage of nodes are found to be metastatic, a fact that must be weighed against potential complications such as lymphedema.Without a real-time in vivo or in situ intraoperative imaging tool to provide a microscopic ... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Eric J. Chaney

12. Measurements of Biomechanics by Dynamic Optical Coherence Elastography

    Explore Article Optical Coherence Tomography News (Feb 21 2010)

    ...t from remote excitation and the ability to maintain a sterile in vivo environment Xing Liang and Stephen A. Boppart Beckman Institute of Advanced Science and Technology University of Illinois at Urbana-Champaign F......oc. SPIE 68471B (2008). 3. X. Liang, et al. Opt. Express 16, 11052-11065 (2008). 4. X. Liang and S. A. Boppart, IEEE T. Bio-Med. Eng. (2009). 5. X. Liang, et al. Opt. Lett. 34, 2894-2896 (2009). (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Xing Liang

13. Resonant acoustic spectroscopy of soft tissues using embedded magnetomotive nanotransducers and optical coherence tomography

    Explore Article Institute of Physics (Feb 1 2010)

    ...1088/0031-9155/55/4/019 Help PDF (808 KB) | References Amy L Oldenburg^1,2 and Stephen A Boppart^1,3,4 ^1 Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Ch... (Read Full Article)
    

    Comment on Article Mentions:   University of Illinois at Urbana-Champaign   Stephen A. Boppart   Amy L. Oldenburg

14. Three Dimensional OCT in the Engineering of Tissue Constructs: A Potentially Powerful Tool for Assessing Optimal Scaffold Structure

    Explore Article Comcast.net (Jan 9 2010)

    ... imaging modality in tissue engineering. Phys Med Biol 2006; 51(7): 1649-59. Ko HJ, Tan W, Stack R, Boppart SA. Optical coherence elastography of engineered and developing tissue. Tissue Eng 2006; 12(1): 63-73.... (Read Full Article)
    

    Comment on Article Mentions:   Brigham and Women’s Hospital   Mark E. Brezinski   Harvard University

15. Partially coherent illumination for inverse scattering full-field interferometric synthetic aperture microscopy

    Explore Article uspto.gov (Jan 4 2010) Microscopy , Patents

    Methods and apparatus for three-dimensional imaging of a sample. A source is provided of a beam of light characterized by partial spatial coherence. The beam is focused onto a sample and scattered light from the sample is superposed with a reference beam derived from the source onto a focal plane detector array to provide an interference signal. A forward scattering model is derived relating measurement data to structure of an ... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Daniel L. Marks

16. Optics may speed breast cancer diagnosis

    Explore Article Futurity.org (Dec 10 2009) Oncology

    ...l-time information on breast cancer tissue margins while still in the operating room. Developed by Stephen Boppart, professor of electrical and computer engineering, bioengineering, and medicine, at the University ......echnology for imaging subsurface biological tissue—to provide high-resolution, micron-scale images. Boppart put his system to the test through a collaborative study involving his laboratory at Illinois’s Bec... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

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